399 results match your criteria: "Aristotle University Medical School[Affiliation]"

Background: We investigated the accuracy of targeted resection thickness in patients undergoing primary Total Knee Arthroplasty (TKA) using the ROSA robotic system.

Methods: Calliper measurements of the distal femur (DF), proximal tibia (PT), and posterior condyles (PC) were taken in 44 patients from June 2023 to January 2024.

Results: Planned and actual resection depth difference was 0.

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European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.

J Eur Acad Dermatol Venereol

December 2024

European Hidradenitis Suppurativa Foundation e.V., Dessau, Germany.

Introduction: This second part of the S2k guidelines is an update of the 2015 S1 European guidelines.

Objective: These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS).

Methods: The chapters have been selected after a Delphi procedure among the experts/authors.

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Purpose: The dual mobility cup (DMC) reduces the dislocation rates in total hip arthroplasty (THA). DMC systems include anatomical (non-modular or monoblock) (ADM) and modular dual mobility (MDM) components (Stryker Orthopaedics, Mahwah, NJ, USA). This review aims to assess differences between these two types of DMC implants concerning dislocation and revision rates, as well as patient-reported outcomes.

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What Is the Optimal Interval Between Bilateral Total Knee Arthroplasty when Performed Under Separate Anesthesia?

J Arthroplasty

October 2024

Department of Anaesthesiology, Critical Care & Pain Management, Hospital for Special Surgery, New York, New York; Department of Anaesthesiology, Weill Cornell Medical College, New York, New York.

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Article Synopsis
  • - Current research indicates that asymptomatic atrial fibrillation (AF) may lead to similar risks of stroke and mortality as symptomatic AF, despite conflicting previous findings.
  • - A review of 36 studies, involving over 217,000 participants, showed no significant differences in all-cause mortality, stroke, or other major health outcomes between symptomatic and asymptomatic AF patients; however, symptomatic patients had a higher risk of developing new heart failure.
  • - Symptomatic patients tended to receive more aggressive treatments like antiarrhythmic drugs and ablation therapy, while asymptomatic patients had a higher chance of progressing to permanent AF.
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Article Synopsis
  • This study analyzed long-term outcomes of young patients under 65 with femoral neck fractures (FNFs) treated with closed reduction and internal fixation (CRIF) over the past decade.
  • Involving 52 patients, results showed that no cases of non-union occurred, but 17.3% developed avascular necrosis (AVN) requiring total hip arthroplasty (THA) after about 1.68 years.
  • Factors like age, trauma type, sex, and treatment conditions did not significantly impact patient outcomes, but the time from trauma to surgery was shorter for those who later underwent THA.
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Objective: Aneurysmal degeneration of the common iliac artery (CIA) can pose a challenge to achieve distal landing zone sealing at the time of endovascular abdominal aortic aneurysm repair (EVAR). The aim of this study was to summarize the current literature regarding the bell-bottom technique (BBT) for ectatic CIAs during EVAR.

Methods: This study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines.

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Piriformis preserving posterior approach STAR for primary and primary complex total hip arthroplasty: Excellent safety and efficacy in a single blinded prospective single surgeon cohort of 522 patients with a mean follow-up of 2 years.

SICOT J

September 2024

Academic Orthopaedic Department, Aristotle University Medical School, General Hospital Papageorgiou, Ring Road Efkarpia, Thessaloniki 56403, Greece - Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI)-Aristotle University of Thessaloniki (AUTH), Balkan Center, Buildings A & B, 10th km Thessaloniki-Thermi Rd, P.O. Box 8318, Thessaloniki 57001, Greece - Tsiridis Orthopaedic Institute - ICAROS Clinic, Thessaloniki 55535, Greece.

Introduction: STAR (Superior Transverse Anatomic Reconstruction), a piriformis-preserving posterior approach, has not been extensively studied. Our study aimed to assess the STAR approach's safety and efficacy by recording postoperative complication rates and measuring implantation accuracy in a single surgeon prospective cohort with a mean follow-up of two years.

Methods: The study involved 522 patients with elective primary or complex primary total hip arthroplasty (THA) performed by a senior surgeon using the STAR approach between 2019 and 2023.

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Introduction: Despite the technological advancements in catheter ablation strategies, the recurrence of atrial fibrillation (AF) post-ablation remains a concern that requires further investigation. Glucagon-like peptide 1 (GLP-1) receptor agonists have shown a significant effect on weight reduction, which in turn is associated with freedom from AF recurrence in both patients who are obese and not obese undergoing ablation. Therefore, we aimed to summarize the available evidence on the efficacy of GLP-1 receptor agonists in maintaining sinus rhythm post-ablation.

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Understanding Type II Endoleak: A Harmless Imaging Finding or a Silent Threat?

J Clin Med

July 2024

Division of Vascular and Endovascular Surgery, Department of Surgery, Stony Brook University Hospital, Stony Brook, NY 11794, USA.

Type II endoleak (T2EL) represents a challenging clinical entity following endovascular abdominal aortic aneurysm repair (EVAR). Although several studies have suggested that T2ELs are related to an increased risk of aneurysm sac growth and subsequent rupture, the exact role that T2ELs play in long-term outcomes remains debatable. Understanding the pathophysiology, diagnostic modalities, and management options of T2ELs is important for patients' safety and proper resource utilization.

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Article Synopsis
  • Right ventricular (RV) failure significantly affects survival rates in heart failure (HF) patients, prompting the investigation of cardiac resynchronization therapy (CRT) for improving RV function.
  • A systematic review analyzed data from 30 studies, revealing CRT significantly enhances RV function metrics such as fractional area change and tricuspid annular plane systolic excursion while lowering pulmonary artery pressure.
  • Despite positive findings for some RV function indices, further research is needed to understand the long-term benefits of CRT and identify which patients gain the most from the treatment.
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Liposarcoma is the most common soft tissue sarcoma type in adults, originating mainly from the retroperitoneum and lower extremities. Mediastinal liposarcomas constitute an extremely rare clinical entity of mesenchymal origin. Among subtypes, dedifferentiated liposarcoma is characterized by poor survival, but little is known about its biological behavior.

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Background Clinical and translational research suggests that mineralocorticoid receptor antagonists (MRAs) may prevent atrial fibrosis and electrical remodeling associated with atrial fibrillation (AF). This study aimed to consolidate existing evidence from randomized controlled trials (RCTs) evaluating the effect of MRAs on incident or recurrent AF. Methods Medline, Cochrane Library and Scopus were searched until February 12, 2024.

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Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Acute Coronary Syndrome: A Modern Cinderella?

Clin Ther

November 2024

School of Medicine, Department of Health Promotion, Mother and Child Care (Promise), Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.

Purpose: Atherosclerotic cardiovascular disease remains a prominent global cause of mortality, with coronary artery disease representing its most prevalent manifestation. Recently, a novel class of antidiabetic medication, namely sodium-glucose cotransporter-2 (SGLT2) inhibitors, has been reported to have remarkable cardiorenal advantages for individuals with type 2 diabetes mellitus (DM), and they may reduce cardiorenal risk even in individuals without pre-existing DM. Currently, there is no evidence regarding the safety and efficacy of these drugs in acute coronary syndrome (ACS), regardless of diabetes status.

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Background: Effective surgical wound management in total knee arthroplasty (TKA) is crucial for optimal healing and patient outcomes. Despite surgical advances, managing wounds to prevent complications remains challenging. This study aimed to identify and address evidence gaps in TKA wound management, including preoperative optimization, intraoperative options, and postoperative complication avoidance.

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Background: There is currently no staging system for cutaneous squamous cell carcinoma (cSCC) that is adapted to decision-making and universally used. Experts have unconscious ability to simplify the heterogeneity of clinical situations into a few relevant groups to drive their therapeutic decisions. Therefore, we have used unsupervised clustering of real cases by experts to generate an operational classification of cSCCs, an approach that was successful for basal cell carcinomas.

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maturation of oocytes in light of ovarian mitochondrial improvement: effectiveness and safety.

Zygote

June 2024

Unit for Human Reproduction, 1st Department of Obstetrics and Gynaecology, Aristotle University Medical School, Papageorgiou General Hospital, Thessaloniki, Greece.

maturation of oocytes (IVM) represents an assisted reproductive technique that involves the minimal or absence of ovarian stimulation and is beneficial to specific groups of patients. These may include women with polycystic ovarian syndrome and/or patients who need a fertility preservation option before undergoing gonadotoxic treatment. However, when IVM is applied in cases where it is not recommended, it can be considered as an add-on technique, as described by the ESHRE Guideline Group on Female Fertility Preservation.

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Letter to the Editor on "Increased Rates of Late Periprosthetic Fractures in Larger Hydroxyapatite-Coated Cementless Stems: Are Collared Stems a Better Alternative for Total Hip Arthroplasty?".

J Arthroplasty

June 2024

Academic Orthopaedic Department, Aristotle University Medical School, General Hospital Papageorgiou, Thessaloniki, Greece; Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI)-Aristotle University of Thessaloniki (AUTH), Balkan Center, Thessaloniki, Greece.

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Article Synopsis
  • Inconsistent reporting of outcomes in rosacea clinical trials is hindering accurate data analysis and meta-analyses, highlighting the need for standardized outcome measures.
  • A core outcome set (COS) was developed through systematic literature reviews and a Delphi process, involving feedback from physicians and patients to identify essential outcomes in rosacea trials.
  • The final COS includes 8 key domains, such as skin symptoms and patient satisfaction, which aim to enhance the comparability and relevance of future rosacea research and interventions.
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Surveillance of adults with congenital heart disease: Current guidelines and actual clinical practice.

Int J Cardiol

July 2024

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton & Harefield Hospitals, Guys & St Thomas's NHS Trust, London, UK; Department of Cardiology III - Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Albert-Schweitzer Campus 1, Muenster, Germany; School of Cardiovascular Medicine & Sciences, Kings College, London WC2R 2LS, UK.

Article Synopsis
  • Congenital heart disease (CHD) is the most prevalent birth defect, with over 90% of affected children now surviving into adulthood due to advances in medical care.* -
  • A survey of cardiologists showed that ECG and echocardiography are the most common diagnostic tests used for adults with CHD, and many doctors also focus on the psychosocial aspects of care.* -
  • There are inconsistencies between current clinical practices and established guidelines, especially in managing patients with mild CHD lesions, with American guidelines recommending more frequent monitoring compared to European guidelines.*
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