Computational investigation of the social function of domestic cat facial signals.

There is growing interest in the facial signals of domestic cats. Domestication may have shifted feline social dynamics towards a greater emphasis on facial signals that promote affiliative bonding. Most studies have focused on cat facial signals during human interactions or in response to pain.

MAD2L2 Dimerization Is Not Essential for Mitotic Regulation.

MAD2L2 is a small HORMA domain protein that plays a crucial role in DNA repair and mitosis. In both TLS and shieldin, the dimerization of MAD2L2 via its HORMA domain is critical for the stability and function of these complexes. However, in mitosis, the dimerization state of MAD2L2 remains unknown.

Abolishing age criterion to determine organ transplant recipients in Israel: A qualitative study of medical staff perceptions.

Introduction: Since April 2014 the age limitation on candidates listed for organ transplantation in Israel was abolished following the recommendations of a Public Committee. In this research the new policy was examined in light of scarce medical resources and the increased rate of aging in Israel.

Methods: The opinions of twelve medical staff regarding the policy change were analyzed by a qualitative methodology, using semi-structured interviews.

Spontaneous photon emission by shaped quantum electron wavepackets and the QED origin of bunched electron beam superradiance.

It has been shown that the spontaneous emission rate of photons by free electrons, unlike stimulated emission, is independent of the shape or modulation of the quantum electron wavefunction (QEW). Nevertheless, here we show that the quantum state of the emitted photons is non-classical and does depend on the QEW shape. This non-classicality originates from the shape dependent off-diagonal terms of the photon density matrix.

The First Pilot Epigenetic Type Improvement of Neuropsychiatric Symptoms in a Polymorphic Dopamine D2 (-DRD2/ANKK (Taq1A)), OPRM1 (A/G), DRD3 (C/T), and MAOA (4R) Compromised Preadolescence Male with Putative PANDAS/CANS: Positive Clinical Outcome with Precision-Guided DNA Testing and Pro-Dopamine Regulation (KB220) and Antibacterial Therapies.

Pediatric autoimmune neuropsychiatric disorders associated with or without streptococcal and other bacterial infections (PANDAS/CANS) are emerging as a featured pediatric disorder. Although there is some controversy regarding treatment approaches, especially related to the behavioral sequelae, we have hypothesized in other published work that it is characterized by the rapid onset of Reward Deficiency Syndrome (RDS) in children. We propose utilizing a multi-systems biological approach involving the coupling of genetic addiction risk testing and pro-dopamine regulation (KB220/POLYGEN) to help induce "dopamine homeostasis" in patients with PANDAS, especially those with known DNA-induced hypodopaminergia.

Understanding the impact of extreme terrorist events on evacuees and non-evacuees: A study on child aggression and social problems.

This study aimed to examine differences between evacuee and non-evacuee parents regarding their experiences following the October 7th terror attack in Israel, and to assess how parental factors-such as exposure, PTS, functioning, resilience, and trust in authorities-were related to perceived behavioral problems in children. The study included 221 evacuee parents and 262 non-evacuee parents, recruited online through a professional survey company. We hypothesized that perceived child aggression and social problems would increase following the terrorist events, with evacuee parents reporting a greater increase in symptoms due to heightened instability and stress.

Economical-epidemiological analysis of the coffee trees rust pandemic.

Coffee leaf rust is a prevalent botanical disease that causes a worldwide reduction in coffee supply and its quality, leading to immense economic losses. While several pandemic intervention policies (PIPs) for tackling this rust pandemic are commercially available, they seem to provide only partial epidemiological relief for farmers. In this work, we develop a high-resolution spatiotemporal economical-epidemiological model, extending the Susceptible-Infected-Removed model, that captures the rust pandemic's spread in coffee tree farms and its associated economic impact.

Fentanyl Initiation Rate Following the Requirement for Specialist Approval.

Background: Healthcare organizations attempt to address unwarranted fentanyl use, which often leads to increased risk of addiction and overdose.

Objective: To assess the impact of a requirement for a specialist's approval on fentanyl initiation for non-oncological pain.

Design: A retrospective cohort study based on observational data.

Exploring the Interplay of Wavelength, Quantum Yield, and Penetration Depth in In Vivo Fluorescence Imaging.

The intricate interplay between the irradiation wavelength, the fluorophore quantum yield (QY) and penetration depth profoundly influences the efficacy of in vivo fluorescence imaging in various applications. Understanding the complex behavior of fluorescence in vivo, specifically how variations in wavelength affect the QY of commonly used dyes and the depth of imaging is crucial for optimizing fluorescence imaging techniques, as it directly impacts the accuracy and efficiency of imaging in biological tissues. In our study, we explore these dynamics through Monte Carlo simulations conducted under conditions reflective of wide-field fluorescence imaging, examining how variations in wavelength impact the dye's QY and depth of imaging, and consequently, the fluorescence behavior.

Deployment stressors, mental health outcomes, and protective factors among wives of reserve soldiers during the Israel-Hamas War: A latent profile analysis approach.

Deployment to active conflict zones significantly affects military families, with spouses often experiencing heightened stress and mental health challenges. However, research on non-US military spouses, particularly those of reserve soldiers, who may face unique stressors compared to active-duty personnel, remains scarce. This study examined perceived stress profiles among Israeli spouses of reserve soldiers during the ongoing Israel-Hamas War, and their associations with deployment stressors, mental health outcomes, and psychological protective factors.

Can Massive Religious Festival Celebrations Encourage a Faster Spread of a Pandemic? The Case of COVID-19 in Israel.

This paper attempts to evaluate how massive religious festival celebrations can encourage the faster spread of any pandemic according to our problem statement, such as the case of COVID-19. For example, we evaluate Israel's three major religions, namely  Judaism, Christianity, and the Islamic festival  celebrations, respectively. Firstly, we have the traditional Jewish festivities such as Hanukkah, Yom Kippur, Sukkot, and Rosh Hashanah.

Can the subjective perception of trauma effectively differentiate between International Classification of Diseases-11 PTSD and complex PTSD? The 2022 Russian invasion analysis.

Objective: This study is aimed to test the association of the Subjective Traumatic Outlook (STO) concept for distinguishing between posttraumatic stress disorder (PTSD) and complex PTSD. Focusing on identity dimensions within identity theory, the research aims to understand how subjective factors influence psychological outcomes, especially in the context of trauma during prolonged war. Findings can inform our understanding of the perception of trauma during wartime.

Homeopathy for Rheumatological Diseases: A Systematic Review.

Homeopathy has mainly been used to treat several diseases. On the other hand, it has been used in a few rheumatic disorders. The aim of this article is to review the use of homeopathy in rheumatic diseases (RDs).

Community composition and seasonal dynamics of microplastic biota in the Eastern Mediterranean Sea.

Marine plastic pollution poses a growing environmental threat, with microplastics accumulating in the global oceans. This study profiles the seasonal dynamics and taxonomic composition of the plastisphere, the microplastic ecosystem, in the Eastern Mediterranean Sea. Using long-read 16 S and 18 S metabarcoding, we analyzed offshore microplastic and whole seawater samples across each season over a two-year period.

Parenting-related abuse among women survivors of attempted intimate partner homicide.

Background: Despite increasing attention to intimate partner homicide (IPH), there is a significant gap in understanding the continuation of abuse after women survive attempted IPH, particularly in cases involving shared parenthood. The goal of this research is to fill this gap by exploring the specific parenting-related post-separation abuse tactics used by perpetrators, providing critical insights into the ways coercive control extends into shared parenting arrangements and the implications for survivors' healing as well as their children's safety and well-being.

Objective: Coercive control was used as a theoretical framework to explore attempted IPH survivors' experiences of parenting-related post-separation abuse tactics.

The reconstruction of evolutionary dynamics of processed pseudogenes indicates deep silencing of "retrobiome" in naked mole rat.

Approximately half of mammalian genomes are occupied by retrotransposons, highly repetitive interspersed genetic elements expanded through the mechanism of reverse transcription. The evolution of this "retrobiome" involved a series of explosive amplifications, presumably associated with high mutation rates, interspersed with periods of silencing. A by-product of retrotransposon activity is the formation of processed pseudogenes (PPGs)-intron-less, promoter-less DNA copies of messenger RNA (mRNA).

Investigating mood-modification, withdrawal, and sensitization in compulsive sexual behaviour.

Background And Aims: Compulsive Sexual Behaviour (CSB), defined as a persistent failure to control repetitive sexual impulses, has been discussed as a pathological phenomenon for centuries. Various terms, such as excessive sexual behaviour, hyper-sexuality, compulsive sexual behaviour disorder (CSBD), or sexual addiction (SA), have been used to describe it, contributing to ongoing debates about its theoretical framework. The following three studies aim to empirically assess whether CSB exhibits key elements of behavioural addiction (mood-modification, sensitization/tolerance, and withdrawal).

Behavioral and Psychosocial Dynamics of Engagement: The Digital Divide in Artificial Intelligence [AI]-Driven Sports Podcasts.

The digital divide, particularly within the context of Artificial Intelligence (AI) sport podcasts, presents significant behavioral and psychosocial challenges for student engagement. This study examines the disparities in access to and proficiency with Information Communication Technologies (ICTs) across different demographic groups, focusing on gender, age, and religious level. The advent of the commercial web has heightened the significance of these divides, as the first-level digital divide concerns access to the internet, while the second-level digital divide pertains to the ability to use technology proficiently.