Gravitational Hamiltonian Systems and the Retarded Gravity Inequality.

Gravity and electromagnetic interactions are the only fundamental physical interactions (outside the nuclear domain). In this work, we shall concentrate on Hamiltonians containing gravitational interaction, which according to general relativity must be retarded. In recent years, retarded gravity has explained many of the mysteries surrounding the "missing mass" related to galactic rotation curves, the Tully-Fisher relations, and gravitational lensing phenomena.

Dirac Equation and Fisher Information.

Previously, it was shown that Schrödinger's theory can be derived from a potential flow Lagrangian provided a Fisher information term is added. This approach was later expanded to Pauli's theory of an electron with spin, which required a Clebsch flow Lagrangian with non-zero vorticity. Here, we use the recent relativistic flow Lagrangian to represent Dirac's theory with the addition of a Lorentz invariant Fisher information term as is required by quantum mechanics.

Peroxidase-like Nanoparticles of Noble Metals Stimulate Increasing Sensitivity of Flavocytochrome -Based L-Lactate Biosensors.

We report the development of amperometric biosensors (ABSs) employing flavocytochrome (Fc) coupled with nanoparticles (NPs) of noble metals on graphite electrode (GE) surfaces. Each NPs/GE configuration was evaluated for its ability to decompose hydrogen peroxide (HO), mimicking peroxidase (PO) activity. The most effective nanoPO (nPO) was selected for developing ABSs targeting L-lactate.

Ensuring continuity of care in times of crisis: A longitudinal analysis of dementia care delivery during armed conflict.

Background: Individuals with dementia are particularly vulnerable during emergency situations due to challenges with cognition, mobility, and daily functioning. However, little is known about how disruptive events may specifically impact the health of those with dementia.

Objective: To evaluate changes in health outcomes for individuals with and without dementia surrounding the Israel-Gaza war in October 2023.

Spatio-temporal model of combining chemotherapy with senolytic treatment in lung cancer.

Senescent cells are cells that stop dividing but sustain viability. Cellular senescence is the hallmark of aging, but senescence also appears in cancer, triggered by cells stress, tumor suppression of gene activation, and oncogene activity. In lung cancer, senescent cancer cells secrete VEGF, which initiates a process of angiogenesis, enabling the cancer to grow and proliferate.

Sex differences in response to intranasal oxytocin as an adjunctive therapy for patients with severe mental illness.

Studies investigating the potential benefits of intranasal oxytocin (INOT) as an add-on treatment for patients with severe mental illness (SMI) have yielded inconsistent results, potentially due to sex differences in response to INOT. This study explored the differential effects of INOT among male and female patients with SMI. A secondary analysis was conducted on a previously studied group of patients who participated in a double-blind, placebo-controlled trial evaluating the impact of INOT as an add-on treatment for patients with SMI.

Changes in Individual and Dyadic Sexual Behavior Frequencies During Wartime in Israel: How Much, Who, and Why?

Introduction: Understanding the impact of external stressors on human sexuality, especially during war, remains a complex and understudied area. The study's goals were to observe and understand shifts in sexual behavior during the 2023 Israel-Hamas War, with a focus on gender differences. The primary goal is to explore the anticipated decline in sexual activity during wartime, while remaining open to unexpected findings.

Provision of supportive care by an NGO in the face of a dual challenge: cancer and wartime.

Purpose: In this study, we explored the work of Halasartan (Stop Cancer), an Israeli nongovernmental organization (NGO) and unique social support network for cancer patients and survivors aged 18-44, during a war period. Drawing on the conservation of resources (COR) theory, we examined whether self-efficacy, social support, psychological distress, and participation in activities that were geared toward alleviating the war situation at Time 1 (T1) would predict engagement in such activities at Time 2 (T2).

Methods: A longitudinal design with two time-points was used, and NGO members completed self-report questionnaires.

Adolescent Blood Pressure and Early Age Stroke.

Background: Underdiagnosis of relevant risk factors has contributed to the increasing stroke incidence in young adults. Blood pressure cut-off values for adolescents are neither sex specific nor based on cardiovascular outcomes.

Methods: This nationwide, population-based, retrospective cohort study included all Israeli adolescents 16-19 years of age who were medically evaluated before compulsory military service from 1985 to 2013, including routine blood pressure measurements.

His-tag based supramolecular biopolymerization.

The term supramolecular polymer has been applied to polymeric materials in which the individual units, i.e., building blocks-are bound to each other via noncovalent interactions, including electrostatic or hydrogen bonding, as well as metal-ligand conjugation.

Revisiting the alcohol-aggression link: The impact of alcohol consumption patterns.

Laboratory studies have repeatedly reported a link between alcohol and aggression, yet many rely on single-dose administration methods and overlook variations in alcohol consumption patterns. The present study investigates the effects of alcohol on aggressive behavior using a double-blind, placebo-controlled cumulative drinking administration approach that mirrors the natural drinking behaviors often observed in pubs within a laboratory setting. This study also pioneers the examination of how alcohol consumption patterns (light or heavy) moderate the relationship between precise Breath Alcohol Concentration (BrAC) levels and extreme aggressive behavior.

The impact of a 20-h rotating watch schedule on cognitive and mood states in submarine operations.

This is the first study to provide valuable insights into the effects of the Israeli Navy's 20-h rotating watch schedule on submariners' alertness, mood states, risk-taking behaviours, and sleep. Specifically, we assessed the impact of the non-circadian-aligned schedule on cognitive performance, mood, and behavioural outcomes in a highly controlled submarine environment. A total of 20 male submariners participated in an at-sea mission, where their cognitive performance, mood states, risk-taking propensity, and caffeine consumption were measured.

Automated video-based pain recognition in cats using facial landmarks.

Affective states are reflected in the facial expressions of all mammals. Facial behaviors linked to pain have attracted most of the attention so far in non-human animals, leading to the development of numerous instruments for evaluating pain through facial expressions for various animal species. Nevertheless, manual facial expression analysis is susceptible to subjectivity and bias, is labor-intensive and often necessitates specialized expertise and training.

Reevaluating ADHD and its First-Line Treatment: Insights from DSM-5-TR and Modern Approaches.

Is Attention Deficit Hyperactivity Disorder (ADHD) a "brain disorder"? Should it be managed regularly with stimulant drugs? This article critically examines the evolving biomedical discourse surrounding these questions through a close inspection of the latest edition of the influential psychiatric manual - the DSM-5-TR - as well as additional authoritative sources (e.g., previous DSM editions, consensus statements, FDA communications).

Proposal for a new classification of intrauterine adhesions by sites.

The authors propose a new classification of intrauterine adhesions (IUAs) to facilitate understanding for both the gynecologist and the patient, documenting the location and characteristics of the adhesions in a single image. This tool significantly improves surgical planning and patient outcomes in the treatment of intrauterine adhesions. In addition, having a simple and consistent method of describing IUAs will facilitate longitudinal studies tracking the outcomes of various surgical techniques, adhesion barriers and the impact of hormonal treatment.

An international core outcome set for primary progressive aphasia (COS-PPA): Consensus-based recommendations for communication interventions across research and clinical settings.

Introduction: Interventions to treat speech-language difficulties in primary progressive aphasia (PPA) often use word accuracy as a highly comparable outcome. However, there are more constructs of importance to people with PPA that have received less attention.

Methods: Following Core Outcome Set Standards for Development Recommendations (COSSTAD), this study comprised: Stage 1 - systematic review to identify measures; Stage 2 - consensus groups to identify important outcome constructs for people with PPA (n = 82) and care partners (n = 91); Stage 3 - e-Delphi consensus with 57 researchers.

[ASSOCIATION BETWEEN TREATMENT FOR DIABETES MELLITUS AND HYPOGLYCEMIA AMONG HOSPITALIZED PATIENTS WITH HYPOALBUMINEMIA TREATED WITH MEDICAL FOOD].

Introduction: Hypoglycemia may be related to malnutrition or treatment of diabetes. An association between treatment with medical food and lower incidence of hypoglycemia among patients with diabetes and hypoalbuminemia has recently been shown.

Aims: To study the association between hypoglycemia incidence and medical and nutrition treatment for diabetes.

Perspectives on Half-Century of Combat Casualty Care in the Israel Defense Forces Medical Corps.

Background: Military medicine has evolved significantly over the past 50 years, advancing from basic treatments and limited evacuations to sophisticated combat casualty care. Innovations such as hemorrhage control, early blood product administration, and telemedicine have greatly improved battlefield care. Rapid evacuation systems and skilled medical teams have reduced mortality and morbidity rates.

Emotional resilience and sense of danger among doctors in hospitals during periods of heightened tensions and warfare in Israel.

Background: The "Iron Swords" War beginning in October 2023 led to unprecedented levels of shock and trauma across Israel, significantly impacting the Israeli population and medical personnel. This study aimed to evaluate and compare the perceived personal resilience and sense of danger among physicians in hospitals located in different conflict zone proximities in Israel during this period.

Methods: A quantitative, cross-sectional study was conducted from March to August 2024, during an active phase of the war, using a structured anonymous questionnaire.

Computational investigation of the social function of domestic cat facial signals.

There is growing interest in the facial signals of domestic cats. Domestication may have shifted feline social dynamics towards a greater emphasis on facial signals that promote affiliative bonding. Most studies have focused on cat facial signals during human interactions or in response to pain.