13 results match your criteria: "Argentine Catholic University[Affiliation]"
Treatment of Chronic Haemophilic Synovitis with PRP: Clinical and Studies.
Int J Mol Sci
August 2024
Department of Medicine, Argentine Catholic University, Buenos Aires C1032ABS, Argentina.
Intra-articular blood, iron and hemosiderin, hydroxyl radical cytokines, and neo-angiogenesis cause synovial inflammation, which leads to cartilage and joint damage. Platelet-rich plasma (PRP) inhibits most of the mediators that produce and maintain synovitis. We compile here our work showing the clinical effectiveness of intra-articular PRP injections and their potential role in stopping articular cartilage damage due to bleeding and its possible repair.
View Article and Find Full Text PDFDeterminants of clinical response to empirical antibiotic treatment in patients with cirrhosis and bacterial and fungal infections-Results from the ICA "Global Study" (EABCIR-Global Study).
Hepatology
May 2024
Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Background: The administration of an appropriate empirical antibiotic treatment is essential in cirrhosis and severe bacterial infections. We aimed to investigate the predictors of clinical response of empirical antibiotic treatment in a prospective cohort of patients with cirrhosis and bacterial and fungal infections included in the International Club of Ascites "Global Study."
Methods: Patients hospitalized with cirrhosis and bacterial/fungal infection were prospectively enrolled at 46 centers.
Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved.
Nat Med
December 2022
Université de Lorraine, INSERM INI-CRCT, CHRU, Nancy, France.
The EMPEROR-Preserved trial showed that the sodium-glucose co-transporter 2 inhibitor empagliflozin significantly reduces the risk of cardiovascular death or hospitalization for heart failure (HHF) in heart failure patients with left ventricular ejection fraction (LVEF) > 40%. Here, we report the results of a pre-specified analysis that separately evaluates these patients stratified by LVEF: preserved (≥ 50%) (n = 4,005; 66.9%) or mid-range (41-49%).
View Article and Find Full Text PDFRegulation of the cellular redox state and the expression of DNA methyltransferase-1 in peripheral blood mononuclear cells from patients with Graves' disease.
Endocrinol Diabetes Nutr (Engl Ed)
July 2022
Institute of Biomedical Research (BIOMED-CONICET), Argentine Catholic University (UCA), Buenos Aires, Argentina. Electronic address:
Background: Graves' disease is an autoimmune disorder characterised by excessive production of thyroid hormones, which induces increased cellular metabolism in most tissues and increased production of reactive oxygen species (ROS). The aim of this work was to analyse the effect of ROS on cell viability and the expression of catalase (CAT), glutathione peroxidase-1 (GPx-1), superoxide dismutase (SOD-1) and DNA methyltransferase-1 (DNMT-1) in peripheral blood mononuclear cells (PBMC) from patients with newly diagnosed Graves' disease or treated with methimazole.
Patients And Methods: For this study, women patients with newly diagnosed Graves' disease (n=18), treated with methimazole (n=6) and healthy subjects (n=15) were recruited.
Quality of life assessed 6 months after hospitalisation for acute heart failure: an analysis from REPORT-HF (international REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure).
Eur J Heart Fail
June 2022
Vanderbilt University Medical Center, Nashville, TN, USA.
Aims: Recovery of well-being after hospitalisation for acute heart failure (AHF) is a measure of the success of interventions and the quality of care but has rarely been quantified. Accordingly, we measured health status after discharge in an international registry (REPORT-HF) of AHF.
Methods And Results: The analysis included 4606 patients with AHF who survived to hospital discharge, had known vital status at 6 months, and were enrolled in the United States of America, Russian Federation, or Western Europe, where the Kansas City Cardiomyopathy Questionnaire (KCCQ) was administered.
Determining the Likelihood Ratio From Perceptual Attributes of Voice.
J Voice
July 2024
Faculty of Medicine, University of Buenos Aires, Ciudad de Buenos Aires, Argentina.
Purpose: To provide voice experts with a method for determining the likelihood ratio (LR) from the perceptual evaluation of distinctive voice attribute scores. The proposed method aims to obtain the similarity and typicality judgments made by forensic voice experts (FVEs) during the comparison of attributes in voice pairs.
Method: It is based on the scoring method for LR calculation.
Empagliflozin in Heart Failure with a Preserved Ejection Fraction.
N Engl J Med
October 2021
From the Department of Cardiology (CVK) and the Berlin Institute of Health Center for Regenerative Therapies (BCRT), German Center for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin Berlin, Berlin (S.D.A.), Universitätsklinikum des Saarlandes, Homberg (M. Böhm), RWTH Aachen University, Aachen (N.M.), Boehringer Ingelheim Pharma, Biberach (C.Z., S.S.), Boehringer Ingelheim International, Ingelheim (W.J., M. Brueckmann), and the Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann) - all in Germany; the University of Mississippi Medical Center, Jackson (J.B.); National and Kapodistrian University of Athens School of Medicine, Athens (G.F.); Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, and INSERM Unité 1116, CHRU, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists) (J.P.F.), and Université de Lorraine, INSERM INI-CRCT, CHRU (F.Z.) - both in Nancy, France; the Cardiovascular Research and Development Center, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal (J.P.F.); Unidade de Insuficiência Cardíaca, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo (E.B.); Maastricht University Medical Center and the School for Cardiovascular Disease CARIM - both in Maastricht, the Netherlands (H.-P.B.-L.R.); the Department of Medicine, Seoul National University Bundang Hospital, Seoul, South Korea (D.-J.C.); Max Superspeciality Hospital, Saket, New Delhi, India (V.C.); the National Institute of Cardiology, Mexico City (E.C.-V.); McGill University Health Centre, Montreal (N.G.), and St. Michael's Hospital, University of Toronto, Toronto (S.V.) - both in Canada; the Cardiology Service, Fundación Valle del Lili, Universidad Icesi, Cali, Colombia (J.E.G.-M.); the Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium (S.J.); Massachusetts General Hospital and Baim Institute for Clinical Research, Boston (J.L.J.); University Hospital, Santiago de Compostela, Spain (J.R.G.-J.); Heart and Vascular Center, Semmelweiss University, Budapest, Hungary (B.M.); Victorian Heart Institute, Monash University, Melbourne, VIC, Australia (S.J.N.); Argentine Catholic University, and Medical Advisor in Heart Failure, Pulmonary Hypertension and Intrathoracic Transplant at FLENI and IADT Institute - both in Buenos Aires (S.V.P.); Central Michigan University, Mount Pleasant (I.L.P.); Wroclaw Medical University, Wroclaw, Poland (P.P.); the Cardiovascular Department, Cardiology Division, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and Università di Pisa, Pisa (S.T.) - both in Italy; National Heart Centre Singapore, Singapore (D.S.); the Internal Cardiology Department, St. Ann University Hospital and Masaryk University, Brno, Czech Republic (J.S.); the University of Leicester, Glenfield General Hospital, Leicester (I.S.), the University of Glasgow, Glasgow (N.S.), the London School of Hygiene and Tropical Medicine (S.J.P.), and Imperial College, London (M.P.) - all in the United Kingdom; Kyushu University, Fukuoka, Japan (H.T.); the University of Medicine and Pharmacy, Carol Davila University and Emergency Hospital, Bucharest, Romania (D.V.); the Heart Failure Center, Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing (J.Z.); the Veterans Affairs Medical Center, Washington, DC (P.C.); National Heart Centre Singapore, Duke-National University of Singapore, Singapore (C.S.P.L.); Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J.M.S.); and Baylor Heart and Vascular Institute, Dallas (M.P.).
Background: Sodium-glucose cotransporter 2 inhibitors reduce the risk of hospitalization for heart failure in patients with heart failure and a reduced ejection fraction, but their effects in patients with heart failure and a preserved ejection fraction are uncertain.
Methods: In this double-blind trial, we randomly assigned 5988 patients with class II-IV heart failure and an ejection fraction of more than 40% to receive empagliflozin (10 mg once daily) or placebo, in addition to usual therapy. The primary outcome was a composite of cardiovascular death or hospitalization for heart failure.
Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure.
J Hepatol
February 2021
Unit of Internal Medicine and Hepatology (UIMH), Department of Medicine - DIMED, University of Padova, Padova, Italy; European Foundation of Chronic Liver Failure (EF-Clif), Barcelona. Electronic address:
Background & Aims: Bacterial infections can trigger the development of organ failure(s) and acute-on-chronic liver failure (ACLF). Geographic variations in bacteriology and clinical practice could lead to worldwide differences in ACLF epidemiology, phenotypes and associated outcomes. Herein, we aimed to evaluate regional differences in bacterial infection-related ACLF in patients with cirrhosis admitted to hospital.
View Article and Find Full Text PDFChagas Disease and Heart Failure: An Expanding Issue Worldwide.
Eur Cardiol
July 2019
Cardiovascular Division, Sanatorio Güemes Hospital Buenos Aires, Argentina.
Article Synopsis
- Chagas disease, once limited to South America, is spreading globally due to migration and primarily impacts the cardiovascular system, often leading to heart failure.
- The disease causes myocardial damage through immune-inflammatory reactions, resulting in conditions like fibrosis, cardiomyopathy, and arrhythmias.
- Diagnosis involves lab tests for the parasite and assessments of cardiac function, with treatment similar to that for dilated cardiomyopathy, while prevention and early diagnosis are emphasized by international health organizations.
Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide.
Gastroenterology
April 2019
Unit of Internal Medicine and Hepatology, Department of Medicine, University of Padova, Padova, Italy. Electronic address:
Article Synopsis
- Bacterial infections in patients with cirrhosis are common and can be life-threatening, with a multicenter study highlighting the need for better understanding of their prevalence and outcomes across different regions.
- Data from over 1300 patients in 46 hospitals revealed a global multidrug-resistant (MDR) bacteria prevalence of 34%, varying significantly by region, with Asia showing the highest rates.
- MDR infections are linked to higher mortality and complications, emphasizing the importance of timely and effective antibiotic treatment to improve patient survival outcomes.
The mechanisms of spontaneous termination of reentrant supraventricular tachycardias.
Int J Cardiol
July 2015
National Academy of Medicine, Buenos Aires, Argentina.
Article Synopsis
- The study focused on understanding why certain heart arrhythmias (AVNRT and AVRT) can stop on their own during tests, despite the reasons being unclear.
- It analyzed 70 patients who experienced spontaneous termination of these arrhythmias and noted the characteristics leading up to these events, such as changes in heart rhythm intervals.
- Findings revealed that most terminations were linked to prolonged signals in the heart before stopping (Mobitz type-I), while a significant portion ended suddenly without warnings (Mobitz type-II), suggesting that fatigue in the heart's electrical pathways plays a role in this spontaneous termination.
Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina.
Anthropol Anz
October 2015
University of Buenos Aires, Argentine Society of Radiology.
Prostate carcinoma is a common malignant neoplasia that mostly metastasizes to bone in males. Nonetheless, the number of paleopathological cases reported is very small. Most of them were identified in Europe, and only two came from South American individuals.
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