From Whole-Brain Radiotherapy to Immunotherapy: A Multidisciplinary Approach for Patients with Brain Metastases from NSCLC.

Non-small cell lung cancer patients with brain metastases have a multitude of treatment options, but there is currently no international and multidisciplinary consensus concerning their optimal treatment. Local therapies have the principal role, especially in symptomatic patients. Advances in surgery and radiation therapy manage considerable local control.

Telemedicine Systems in Uterine Transplant: A Feasibility and Reliability Study of the Pre-Grafting Teleradiological Evaluation of the Uterus Graft.

The pre-grafting Tele-Radiological (TRE) evaluation of the Uterus Graft (UG) on Telemedicine Systems, in Uterus Transplant (UT) is studied by diagnostic sensitivity-specificity analysis based on simulation of TRE of the UG on 10 MR sets of female pelvic digital images by two radiologists, assessing a. The vascular variations of the grafts, and b. The inflammatory and neoplastic lesions of the UG.

The Digital Microscopy in Organ Transplantation: Ergonomics of the Tele-Pathological Evaluation of Renal and Liver Grafts.

Aim: Ergonomics of Digital Microscopy (DM) based on virtual slides, on Telemedicine Systems (TS) for Tele-Pathological (TPE) evaluation of the grafts (G) in organ transplantation (OT).

Material And Methods: Simulation of DM on TS based TPE by 2 specialists on a total of 238 human Renal Graft (RG) and 172 Liver Graft (LG) tissues digital microscopic images diagnosing inflammatory and neoplastic lesions on four different electronic spaces (ES).

Results: DM on TS for TPE in OT is elaborated perfectly on the ES of a Desktop, followed by the ES of the applied Exp.

Mobile tele-medicine systems in the multidisciplinary approach of diabetes management : the remote prevention of diabetes complications.

Aim: Evaluation of feasibility and reliability of Mobile-Telemedicine Systems (M-TS) in the remote prevention of diabetes related complications.

Material And Methods: A feasibility-reliability evaluation based on a simulating experimentation by ten specialists (N=10) who examined a diabetic patient on the electronic space of a mobile experimental telemedicine system (MU-Exp.-TS).

Telemedicine systems in organ transplantation: a feasibility and reliability study of the integrated teleradiological and tele-pathological evaluation of the cardiac graft.

Unlabelled: Aim. Feasibility and reliability of the integrated Tele-Radiological (TRE) and Tele-Pathological (TPE) evaluation of the Cardiac Graft (CG) on Telemedicine Systems.

Material And Methods: Sensitivity-specificity analysis by a simulation of TRE of CG on 15 MR thoracic images by two radiologists and of TPE by 20 specialists based on total 100 human CG digital images, assessing injuries/trauma and lesions.

Integrated Tele-radiological and Tele-pathological Evaluation of Pulmonary Grafts for Reducing the Rate of Injured and Diseased Grafts, in Lung Transplant.

Aim: Feasibility and reliability assessment of the integrated Tele-Radiological (TRE) and Tele-Pathological (TPE) evaluation of the Pulmonary Graft (PG) on Telemedicine Systems, in Lung Transplant (LT).

Material And Methods: Sensitivity-specificity by simulating TRE of PG on 15 MR thoracic images by two radiologists and TPE by 20 specialists based on a total of 100 human PG digital images.

Results: Integration of TRE and TPE of PG showed an accuracy of 94.

Telemedicine systems in organ transplantation: a feasibility and reliability study of the integrated teleradiological and tele-pathological evaluation of liver graft.

Aim: To determine feasibility and reliability of the integrated Tele-Radiological (TRE) and Tele-Pathological (TPE) evaluation of the Liver Graft (LG) on Telemedicine Systems (TS).

Material And Methods: A sensitivity-specificity analysis by a simulation of the TRE of LG on 15 MR abdominal images by a radiologist and of the TPE of LG by 26 specialists based on 130 human LG images assessing damages and lesions.

Results: The integrated analysis of TRE and TPE of LG showed: Sensitivity=96.

Telemedicine systems in organ transplantation: a feasibility and reliability study of the integrated teleradiological and tele-pathological evaluation of pancreas graft.

Aim: To determine feasibility and reliability of the integrated Tele-Radiological (TRE) and Tele-Pathological (TPE) evaluation of the Pancreas Graft (PG) on Telemedicine Systems (TS).

Material And Methods: A sensitivity-specificity analysis by a simulation of the TRE of PG on 15 MR abdominal images by a radiologist and of the TPE of PG by 26 specialists based on 130 human PG images assessing damages and lesions.

Results: The integrated analysis of TRE and TPE of PG showed: Sensitivity=93.

Telemedicine systems in organ transplantation: a feasibility and reliability study of the integrated teleradiological and tele-pathological evaluation of renal graft.

Aim: To determine feasibility and reliability of the integrated Tele-Radiological (TRE) and Tele-Pathological (TPE) evaluation of the Renal Graft (RG) on Telemedicine Systems (TS).

Material And Methods: A sensitivity-specificity analysis by a simulation of the TRE of RG on 15 MR abdominal images by a radiologist and of the TPE of RG by 26 specialists based on 130 human RG images assessing damages and lesions.

Results: The integrated analysis of TRE and TPE of RG showed: Sensitivity=96.

Telepathology as a method to optimize quality in organ transplantation: a feasibility and reliability study of the virtual benching of liver graft.

Aim: To search feasibility and reliability of Telemedicine Systems (TS) in the procurement of Liver Transplantation.

Material And Methods: By an experimental TS, twenty six (n=26) specialists based on a hundred and thirty (N=130) simulated remote image examinations, assessed sensitivity-specificity of the remote examination of Liver Graft (LG) about diseases and damages (Virtual Benching=VB).

Results: Analysis showed: injuries (sensitivity=96%), injuries of the capsula (sensitivity=91.

Telepathology as a method to optimize quality in organ transplantation: a feasibility and reliability study of the virtual benching of pancreas graft.

Aim: To search feasibility and reliability of Telemedicine Systems (TS) in the procurement of Pancreas Transplantation.

Material And Methods: By an experimental TS, twenty six (n=26) specialists based on a hundred and thirty (N=130) simulated remote image examinations, assessed sensitivity-specificity of the remote examination of Pancreas Graft (PG) about diseases and damages (Virtual Benching=VB).

Results: Analysis showed: Injuries (sensitivity=100%), injuries of the capsula (sensitivity=84.

Tele-medicine systems in the coordination process of organ transplantation.

Aim: To search feasibility and reliability of Telemedicine Systems (TS) in the Coordination Process (CP) of Organ Transplantation (OT).

Material & Methods: Forty participants (n=40) were divided in two groups, the specialists and the non specialists and comparatively simulated the telephone/fax and the TS based CP of a renal transplant scenario.

Results: There was no statistically significant difference between the two groups regarding feasibility and reliability of TS in CP.

Acupuncture as an adjunctive therapy to pharmacological treatment in patients with chronic pain due to osteoarthritis of the knee: a 3-armed, randomized, placebo-controlled trial.

The efficacy of acupuncture as an adjunctive therapy to pharmacological treatment of chronic pain due to knee osteoarthritis was studied with a 3-armed, single-blind, randomized, sham-controlled trial; it compared acupuncture combined with pharmacological treatment, sham acupuncture including pharmacological treatment, and pharmacological treatment alone. A total of 120 patients with knee osteoarthritis were randomly allocated to 3 groups: group I was treated with acupuncture and etoricoxib, group II with sham acupuncture and etoricoxib, and group III with etoricoxib. The primary efficacy variable was the Western Ontario and McMaster Universities (WOMAC) index and its subscales at the end of treatment at week 8.

Infected Venous Leg Ulcers: Management With Silver-releasing Foam Dressing .

The aim of this work was to study the safety and effectiveness of silver foam dressing (Contreet® Ag, Coloplast, Humlebaek, Denmark) in promoting the healing of infected venous ulcers over 9 weeks of treatment. Forty-two patients with infected venous ulcers were included and randomized into two groups. Group A had 21 patients (12 women and 9 men, mean age 61.

Altered expression of adhesion molecules in inflammatory cervical smears.

Objective: The aim of the present study was to evaluate the expression of pan-cadherin and beta-catenin in cervical smears with various types of infectious agents.

Patients And Methods: Cervical smears obtained from 53 women, aged 21-65 years, with a diagnosis of specific inflammation were examined in our study. Eighteen subjects were infected by Candida albicans, 18 by Gardnerella vaginalis, nine by Bacteroides spp.

Interstitial magnetic resonance lymphography with gadobutrol in rabbits and an initial experience in humans.

The purpose of this study was first to evaluate gadobutrol as a contrast agent for interstitial Magnetic Resonance Lymphography (MRL) in rabbits, and second, to extend the study to humans, if the initial results were satisfactory. In our experiment, gadobutrol was injected into twelve white New Zealand rabbits. In nine animals, 0.