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Low-dose oral vitamin K is safe and effective for outpatient management of patients with an INR>10.

Thromb Res

December 2004

Department of Molecular Medicine and Haematology, National Health Laboratory Service, Area 454 Johannesburg Hospital, P.O. Box 2000, Johannesburg Gauteng, South Africa.

Background: Low-dose oral vitamin K effectively returns an international normalized ratio (INR) between 4.5 and 10.0 to an INR of 2.

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