2,080 results match your criteria: "Aravind Eye Hospital & Post-Graduate Institute[Affiliation]"

Topic: The systematic review and meta-analysis consolidates the extant body of evidence comparing reliability and agreement between transpalpebral tonometers (TTs) and Goldmann applanation tonometer (GAT).

Clinical Relevance: With a global prevalence of 3.54 percent, glaucoma stands as the second leading cause of preventable blindness.

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To determine the presenting clinical characteristics of patients with rhegmatogenous retinal detachment (RRD) who underwent scleral buckling and the impact on final visual outcomes and to determine the postoperative primary attachment rate, complications, and subsequent management. This retrospective observational study comprised patients with RRD who had scleral buckling surgery from January 2016 to December 2021 with a minimum follow-up of 6 months. The study comprised 307 eyes of 290 patients; 97% of eyes were phakic.

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Purpose: To report an incidence of procedure-related complications in preterm infants with retinopathy of prematurity (ROP) treated with intravitreal anti-VEGFs injection in both eyes on the same day.

Design: Retrospective, multicenter case series.

Subjects: Preterm infants with ROP treated with anti-VEGF bilaterally on the same day.

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Clinical Evaluation of a Novel CRISPR-Cas12a-Based RID-MyC Assay for the Diagnosis of Fungal Endophthalmitis.

Ophthalmol Retina

November 2024

Department of Microbiology, Aravind Medical Research Foundation, Madurai, Tamil Nadu, India; Aravind Medical Research Foundation Regional Centre, Coimbatore, Tamil Nadu, India; Department of Cataract Services, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India. Electronic address:

Objective: This study evaluated the RID-MyC (Rapid Identification of Mycoses using clustered regularly interspaced short palindromic repeats [CRISPR]) assay, a CRISPR/Cas12a-based diagnostic tool, for its efficacy in diagnosing fungal endophthalmitis (FE) compared with panfungal polymerase chain reaction (PCR) and culture methods.

Design: A comparative cross-sectional study assessing the performance of the RID-MyC assay against established diagnostic modalities for FE.

Subjects: The study included 133 intraocular samples from 117 patients with suspected microbial endophthalmitis.

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Purpose: This study aimed to analyze the clinical presentation, treatment outcomes, and histopathology features of ocular surface squamous neoplasia (OSSN) in a South Indian population and correlate the area of lesions to the histopathological grade/severity of carcinoma in situ (CIN) and squamous cell carcinoma (SqCC) invasive and noninvasive tumors.

Methods: The study was a retrospective cross-sectional study. The study reviewed electronic medical records (EMRs) of 99 eyes of 99 South Indian patients who underwent en bloc excision and biopsy for tumors in the corneal and conjunctival epithelium with suspicion of OSSN over 1 year from January 2019 to December 2019.

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Purpose: To evaluate higher order aberrations (HOA) in different types of posterior capsule opacification (PCO) and analyze its changes fosllowing Nd:YAG laser posterior capsulotomy (LPC).

Settings: Tertiary care ophthalmic hospital.

Design: Prospective, comparative, observational study.

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A Computational Framework for Intraoperative Pupil Analysis in Cataract Surgery.

Ophthalmol Sci

August 2024

Kellogg Eye Center, Department of Ophthalmology & Visual Sciences, University of Michigan, 1000 Wall Street, Ann Arbor, Michigan, 48105.

Purpose: Pupillary instability is a known risk factor for complications in cataract surgery. This study aims to develop and validate an innovative and reliable computational framework for the automated assessment of pupil morphologic changes during the various phases of cataract surgery.

Design: Retrospective surgical video analysis.

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Purpose: To compare the rate of re-detachment in patients with rhegmatogenous retinal detachment and Grade-C PVR following vitreoretinal surgery, with and without serial intravitreal injections of methotrexate.

Methods: It was a randomized control trial. Patients aged more than 18 years undergoing pars plana vitrectomy for rhegmatogenous retinal detachment with PVR grade C or more were included in the study.

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Aims: This report summarizes clinical findings, diagnosis, management, and long term outcomes of a recalcitrant and keratitis.

Methods And Materials: An otherwise healthy male patient presented with a corneal infiltrate with predominantly fungal characteristics, but atypical in terms of progression. The infiltrate remained undiagnosed even after several scrapings, and aqueous tap cultures.

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Purpose: Surgical outcome of presumed Autosomal Recessive Bestrophinopathy (ARB)with full thickness macular hole and retinal detachment managed by pars plana vitrectomy.

Methods: A retrospective observational case series of two eyes of two patients who underwent 25 G pars plana vitrectomy with peeling of internal limiting membrane and SF6 tamponade and were assessed with respect to best corrected visual acuity, fundus photographs and spectral domain optical coherence tomography.

Results: Type 1 closure of macular hole was achieved along with resolution of retinal detachment in both patients.

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Background: Glaucoma is an irreversible silent and dangerous eye condition that leads to damage of the optic nerve head. This study aimed to determine the outcome of targeted glaucoma outreaches done in the University of Ilorin Teaching Hospital over three years with a view to early detection and timely institution of management.

Methods: The study is a retrospective review of 3 targeted hospital-based glaucoma screenings, World Sight Day of 2019 (140 participants), World Glaucoma Week of 2020 (176 participants), and World Glaucoma Week of 2022 (183 participants).

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Objective: Characteristics of individuals with angle closure may be useful in targeted screening of family members. Here, we assess if findings gathered during examination and imaging of patients with a known angle-closure diagnosis (probands) could better determine the risk of angle closure in the patients' siblings.

Design: Cross-sectional study of patients with known angle closure and their siblings.

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Article Synopsis
  • Secondary angle closure glaucoma (SACG) differs from primary angle closure glaucoma, often presenting acutely and involving various ocular and systemic associations, which can complicate diagnosis and treatment.
  • *Prompt diagnosis is crucial, and the video outlines different imaging techniques like optical coherence tomography and ultrasound biomicroscopy to identify the causes of SACG effectively.
  • *The video highlights the various mechanisms behind SACG, including those with and without pupillary block, and offers insights on their treatment options.*
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Purpose: To document how acute cerebrovascular accidents (CVAs) present first to an ophthalmologist.

Methods: Retrospective, observational, unicentric hospital-based study. The electronic medical records of new patients who presented to the Neuro-ophthalmology department of a tertiary eye hospital in the month of August 2022 were reviewed.

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Purpose: To report the incidence, etiology, and risk factors for tube explantation in patients undergoing patch-free glaucoma drainage device (GDD).

Methods: Of the total 1303 patients who underwent patch-free GDD (703 non-valved GDD and 600 valved GDD) for refractory glaucoma during January 2020-October 2023, we identified five cases of postoperative complications following GDD that required tube or shunt removal.

Results: Median (IQR) age of our study cohorts was 54.

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Article Synopsis
  • The study investigates the use of botulinum toxin A (BTX-A) in treating acute acquired comitant esotropia (AACE) in children and young adults, particularly related to increased screen time during the COVID-19 pandemic.
  • Researchers analyzed data from 27 patients who received BTX-A injections to correct misalignment of the eyes caused by excessive use of devices like laptops and smartphones, focusing on the changes in eye deviation and binocular vision post-treatment.
  • Results indicated that BTX-A was effective, with significant improvements in eye alignment and visual function noted, especially when treatment was administered early after symptom onset.
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Article Synopsis
  • The study examined the occurrence and characteristics of hemifacial spasm (HFS) in 85 patients at a South Indian eye care center, focusing on potential links to systemic diseases.
  • The average age of patients was around 56 years, with a majority experiencing left-side involvement and primary HFS; MRI showed neurovascular conflicts in some cases.
  • The findings suggested a significant association between HFS and hypertension, indicating that further research is needed to clarify this relationship.
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