15 results match your criteria: "Arak University of Medical Sciences and Khansari Hospital[Affiliation]"

Article Synopsis
  • This study explored how well machine learning models using mpMRI radiomic features can classify Gleason grade groups (GG) in prostate cancer.
  • It involved analyzing data from 203 patients who had pre-biopsy mpMRI scans, using various feature selection methods and machine learning classifiers to assess model performance.
  • The best-performing model achieved impressive accuracy and sensitivity (97.0% and 98.0% respectively) for classifying prostate cancer into five GG categories, demonstrating the effectiveness of this non-invasive approach.
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Quantification of the Most Effective X-Ray Dosage for Inhibiting Invasion of Glioma Cell Line.

Asian Pac J Cancer Prev

December 2024

Department of Biotechnology and Molecular Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran.

Background: One key feature that distinguishes cancerous cell populations from their normal counterparts is a heightened tendency towards uncontrolled growth and invasive activity. Therapeutic techniques like radiotherapy can impact the viability and invasive behavior of cancer cells by modifying the structure of DNA and inducing programmed cell death.

Methods: This research is an experimental study and involved a comprehensive investigation into the effects of 6MV X-ray radiotherapy on various absorbed doses (ranging from 4 to 10 Gy by steps 2Gy) on toxicity, migration, and colony formation in C6 glioblastoma cellular cultures.

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Professionalism and medical ethics, while similar, are often viewed in different contexts. An historical and social science analysis reveals that professionalism is a complex skill that can be developed over time. The key components of professionalism, as defined by the American Physical Therapy Association, include accountability, altruism, compassion, excellence, integrity, professional duty, and social responsibility.

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Occurrence of clear cell carcinoma of the prostate is exceedingly rare and presents a diagnostic dilemma. We describe a case of a 47-year-old male nonsmoker, who presented with a history of frequency, dribbling urination, and dysuria for 6 months. In a digital rectal exam, enlarged prostate with a hard consistency was identified.

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The effect of resistance training on serum levels of sex hormones and sperm quality in male rats under X-ray radiation.

Horm Mol Biol Clin Investig

December 2022

Department of Sports Physiology, Faculty of Sport Sciences and Research Institute of Applied Studies of Sports Sciences, Arak University, Arak, Iran.

Objectives: The present study aims to investigate the effects of resistance training on sex hormones and sperm parameters in male rats under X-ray.

Methods: In this experimental study, 24 Sprague Dawley rats (200-250 g) were randomly assigned into four groups: healthy control, irradiated control, healthy training and irradiated training. Irradiation was induced at a dose of 4 Gy on the whole body.

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Background: Current cancer treatments include surgery, radiotherapy, chemotherapy, and immunotherapy. Despite these treatments, a main issue in cancer treatment is early detection. microRNAs (miRNAs) can be used as markers to diagnose and treat cancers.

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Article Synopsis
  • The study evaluates symmetry and flatness in electron beam radiotherapy using three dosimeters in various field sizes.
  • Measurements were taken in a water phantom for different energy levels (10, 15, and 18 MeV) with a Diode E detector and two types of ionization chambers.
  • Results show minor differences in dosimeter responses, with symmetry and flatness generally increasing with larger field sizes and higher energy, but these differences are not practically significant.
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Electromagnetic fields (EMF) can generate reactive oxygen species and induce oxidative modifications. We investigated the effects of extremely low-frequency electromagnetic fields (ELF-EMF) on oxidative status of plasma and erythrocytes in β-thalassemia major patients and design artificial neural networks (ANN) for evaluating the oxyHb concentration. Blood samples were obtained from age and sex-matched healthy donors (n = 12) and major β-thalassemia patients (n = 12) and subjected to 0.

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The usage of dosimetry of small fields in radiotherapy to measure radiation dose is difficult because of high-dose gradients, lateral electronic disequilibrium, and detector volume effects. In this study, three dosimeters namely, Markus, Semiflex 3D, and Diode E were tested using the Elekta-accelerator electron beams. The electron beam parameters, penumbra, and output factor were determined using these dosimeters for each field size and energy.

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The aim of radiotherapy is to deliver the highest possible radiation dose to the tumor and the lowest radiation to normal tissues surrounding the tumor. In the present study, lymph nodes of the supraclavicular region were treated using two therapeutic techniques, namely photon technique (PT) and combinatory photon-electron technique (CPET). We recruited 50 patients with local lymph node metastasis.

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Background: Metal prostheses in patients affect the radiotherapy dose distribution. Metal prostheses with high density and atomic number cause major changes in scattering and attenuation of radiation. The present study aims to assess the impact of metal knee prosthesis with various dimensions and materials on radiotherapy dose distribution.

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Background: Considering that some vital organs exist in the head and neck region, the treatment of tumors in this area is a crucial task. The existence of air cavities, namely sinuses, disrupt the radiotherapy dose distribution. The study aims to analyze the effect of maxillary, frontal, ethmoid and sphenoid sinuses on radiotherapy dose distribution by Monte Carlo method.

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Purpose: This study investigates the protective properties of Myrtus communis extract against the oxidative effects of extremely low-frequency magnetic fields (ELFMF). Also, this study is aimed to analyze the conformational changes of hemoglobin, oxidative damages to plasma proteins and antioxidant power of plasma following exposure to ELFMF.

Materials And Methods: Adult male rats were divided into 3 groups: (1) control, (2) ELFMF exposure, and (3) ELFMF exposure after M.

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Background: Radiotherapy can often lead to thyroid dysfunction. Some studies demonstrated that treatment of breast cancer by RT can expose thyroid gland to high doses of radiation. The aim of this systematic review is to evaluate consideration of thyroid gland as an organ at risk.

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Background: Megavoltage beams used in radiotherapy are contaminated with secondary electrons. Different parts of linac head and air above patient act as a source of this contamination. This contamination can increase damage to skin and subcutaneous tissue during radiotherapy.

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