Factors associated with adherence to preventive measures against COVID-19, among adult Bahraini residents.

The COVID-19 pandemic has been a life-altering experience. It compelled individuals to alter their attitudes and habits and adopt measures to prevent the risks of infection. This research discusses factors that determine adherence to these measures, with the aim of enhancing compliance in future pandemics.

The Predictive Role of Personality Disorders and Personality Traits in Death Anxiety.

The current study investigates the interplay between personality traits, personality disorders, and death anxiety in a sample of 2331 participants (49% males; 51% females) across two phases. The Death Anxiety Scale, the Psychosocial Personality Inventory, and the Personality Diagnostic Questionnaire were utilized. The findings revealed significant predictive relationships between personality disorders and death anxiety.

Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy.

Platelet-derived growth factor receptor beta (PDGFRβ) belongs to the receptor tyrosine kinase (RTK) protein family and is implicated in several disorders such as hematopoietic, glial, and soft-tissue cancer, non-cancerous disorders, including skeletal defects, brain calcification, and vascular anomalies. The research on small molecule inhibitors targeting PDGFRβ in cancer treatment has seen promising developments, but significant gaps remain. PDGFRβ, receptor tyrosine kinase, is overexpressed in various cancers and plays an important role in tumor progression, making it a potential therapeutic target.

Translating and validating the Ghosting Questionnaire into Arabic: results from classical test theory and item response theory analyses : Short title: the arabic version of the Ghosting Questionnaire.

Background: Ghosting refers to the sudden cessation of communication in interpersonal relationships. Ghosting has gained attention as a phenomenon commonly encountered in the context of digital communication. Earlier studies on ghosting mostly focused on Western societies while, in Arab societies, research into this practice has yet to be initiated.

Berberine-styrene--maleic acid nanomicelles: unlocking opportunities for the treatment and prevention of bacterial infections.

The global spread of multi-drug-resistant (MDR) bacteria is rapidly increasing due to antibiotic overuse, posing a major public health threat and causing millions of deaths annually. The present study explored the potential of nanocarriers for delivering novel and alternative antibacterial agents using nanotechnology-based approaches to address the challenge of MDR bacteria. The purpose was to enhance the solubility, stability, and targeted delivery of berberine (BER) and its synthetic derivative NR16 using Styrene--Maleic Acid (SMA) nanoparticles.

Association of Leukocyte Telomere Length and the Risk of Disease Severity and Metabolic Comorbidities in Arab Patients with Psoriasis.

Introduction: Several studies have related shortened leukocyte telomere length (LTL) with age-related diseases and worse prognosis. Telomere length attrition has recently been associated with inflammatory diseases, including psoriasis (Ps). However, no study has demonstrated an association between LTL and the risk of disease severity and metabolic comorbidities in Arab patients with Ps.

Mapping illegal trade routes of live cheetahs from the Horn of Africa to the Arabian Peninsula.

Less than 7000 cheetahs (Acinonyx jubatus) persist in Africa. Although human-wildlife conflict, habitat degradation, and loss of prey are major threats to cheetah populations, illegal trade in live cubs for pets may have the most significant impact on populations in the Horn of Africa. We developed a novel, stepwise decision support tool to predict probable trafficking routes by leveraging the power of distinct modeling approaches.

Valsalva Maneuver Versus Carotid Sinus Massage for Supraventricular Tachycardia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Supraventricular tachycardia (SVT) is one of the most common cardiac arrhythmias, characterized by a sudden increase in heart rate. Initial management often involves vagal maneuvers, including the Valsalva maneuver (VM) and carotid sinus massage (CSM). VM can be categorized into standard VM (sVM) and modified VM (mVM).

Sarcopenia in the foot on magnetic resonance imaging in patients with diabetes mellitus - a systematic review.

Introduction: Sarcopenia is defined by low measures of muscle quantity, quality and reduced physical performance. It is associated with higher levels of frailty. Individuals with diabetes mellitus (DM) undergo sarcopenia at an accelerated rate resulting in structural changes potentially culminating in limb loss.

From likes to luggage: The role of social media content in attracting tourists.

The tourism industry has become increasingly information-driven where tourists need reliable information to make their travel decisions. Social media content creators have emerged as prominent figures in disseminating authentic and credible information about tourist destinations worldwide. However, scant attention has been paid to explore the role of social media content in influencing tourist inflows and tourist engagement with tourism-related content on social media.

Relationship Between the Serum Cortisol, Insulin, Adrenocorticotropic Hormone (ACTH), and Blood Glucose Levels of Pregnant Women With Gestational Diabetes Mellitus in the Kingdom of Bahrain.

Background Gestational diabetes mellitus (GDM) can be defined as hyperglycemia that develops during pregnancy. GDM poses both maternal and fetal potential risks. Elevated maternal cortisol levels have been linked to maternal hyperglycemia and insulin resistance.

Expanding families: a pilot study on preconception expanded carrier screening in Bahrain.

Background: Preconception expanded carrier screening (ECS) is a genetic test that enables the identification of at-risk carriers of recessive disorders by screening for up to hundreds of genes. Next-generation sequencing (NGS) development has paved the way for its integration into ECS. This study aims to identify the carrier genetic status of couples experiencing or anticipating conception challenges through NGS-based ECS and to gain an overview of the rare genetic disorders in a population with increased consanguinity.

The translation and validation of the surgical anxiety questionnaire into the modern standard Arabic language: results from classical test theory and item response theory analyses.

Background: Preoperative anxiety is commonly found in patients who are waiting for surgery and can lead to negative surgical outcomes. Understanding the sources of surgical anxiety allows healthcare providers to identify at-risk patients and implement psychosocial interventions such as counseling, relaxation techniques, and cognitive‒behavioral therapy to minimize anxiety. Few comprehensive psychiatric measures are available to assess preoperative anxiety in Arabic.

Biogeography of the Iranian snakes.

The events of the Cenozoic era such as mountain formation caused Iran to become one of the most amazing biodiversity hotspots in the world today. This pioneering study on Iranian snake biogeography integrates historical and ecological analyses. A phylogeographic review traces speciation and dispersal, while cluster analysis with a new snake checklist assesses faunistic similarities within Iran and its surroundings.

How accurately can supervised machine learning model predict a targeted psychiatric disorder?

Background: Hoarding disorder (HD) is characterized by a compulsion to collect belongings, and to experience significant distress when parting from them. HD is often misdiagnosed for several reasons. These include patient and family lack of recognition that it is a psychiatric disorder and professionals' lack of relevant expertise with it.

Investigating the capabilities of advanced large language models in generating patient instructions and patient educational material.

Objectives: Large language models (LLMs) with advanced language generation capabilities have the potential to enhance patient interactions. This study evaluates the effectiveness of ChatGPT 4.0 and Gemini 1.

Ingestion of marine debris in juvenile sea turtles in Abu Dhabi, United Arab Emirates.

Marine plastics and other debris constitute a major threat to many marine species. Over 12 million tons of plastics are estimated to reach the oceans annually, causing adverse effects on hundreds of marine species. The Arabian Gulf is a small, sub-tropical and semi-enclosed gulf with extreme environmental conditions with high potential to accumulate marine debris.