Facilitating a More Diverse Workforce: The Value of Mentorship in Cardiothoracic Surgery.

Background: Cardiothoracic surgery (CTS) is one of the least diverse surgical specialties in both gender and race. Aside from the inherent benefits of a diverse working environment, mitigating this diversity gap improves patient care. Mentorship is important for creating a diverse, nurturing environment for trainees.

Determinants of Caregiver Burden Among Spouses of Patients With Kidney Failure: A Qualitative Study.

Rationale & Objective: Spousal caregivers participate extensively in the care of patients with kidney failure. Although previous studies suggested that these caregivers experience a high burden, a comprehensive understanding of the determinants of this burden and strategies to alleviate it are needed. Therefore, this study sought to explore the contributing and alleviating determinants of burden in spousal caregivers of patients with kidney failure.

Systematic Review of Interventions in Early Pregnancy Among Pregnant Individuals at Risk for Hyperglycemia.

Objective: The maternal metabolic environment in early pregnancy can influence fetal growth trajectories. Our objective was to identify interventions initiated in early pregnancy (<20 weeks gestation) in pregnant individuals with risk factors for hyperglycemia and report their impact on primary (neonatal adiposity, small for gestational age, large for gestational age, macrosomia) and secondary outcomes (gestational weight gain, maternal hypertensive disorder, birth injury, NICU admission, preterm delivery, emergency cesarean section).

Data Sources: We searched Cochrane Central database, Medline, Embase, CINAHL databases, and clinicaltrials.

Multi-indices approach for comprehensive appraisal of groundwater quality and the implication on human health in the Amaravathi basin, Southern India.

Groundwater is often used directly by the public in several river basins of India. Hence, this study was carried out with the objective of assessing the quality of groundwater in the Amaravathi basin, India, using a multiple indices approach. Groundwater quality data from 96 monitoring wells were obtained from the Central Groundwater Board and used in this study.

'That's kind of under my work blanket'-redeployment experiences of children's hospital staff during the covid-19 pandemic: a qualitative interview study.

Background: During COVID-19 pandemic, a rapid readjustment to continued delivery of healthcare was required. Redeployment is an intentional process to mobilise human resources by reassigning a healthcare worker to a new role or new work location, to achieve sustainable delivery of patient care. We report redeployment experiences of staff from a specialist children's hospital during first and second waves of the United Kingdom COVID-19 pandemic.

Rural Canadian emergency physician experiences using point-of-care ultrasound.

Objectives: Point-of-care ultrasound (POCUS) is a rapidly evolving and clinically significant skill set that has potential for improving patient care for the approximately 7 million Canadians living in rural and under-resourced environments. A national appraisal of rural POCUS training and utilization is needed to understand barriers to funding and training for rural emergency physicians in Canada. The primary objective of this study was to determine the current level of training and types of POCUS utilization by rural emergency physicians in Canada.

Cohort profile: creation of the SAIL MELD-B e-cohort (SMC) and SAIL MELD-B children and young adult e-cohort (SMYC) to investigate the lived experience of the 'burdensomeness' of multimorbidity.

Purpose: We have established the SAIL MELD-B electronic cohort (e-cohort SMC) and the SAIL MELD-B children and Young adults e-cohort (SMYC) as a part of the Multidisciplinary Ecosystem to study Lifecourse Determinants and Prevention of Early-onset Burdensome Multimorbidity (MELD-B) project. Each cohort has been created to investigate and develop a deeper understanding of the lived experience of the 'burdensomeness' of multimorbidity by identifying new clusters of burdensomeness concepts, exploring early life risk factors of multimorbidity and modelling hypothetical prevention scenarios.

Participants: The SMC and SMYC are longitudinal e-cohorts created from routinely collected individual-level population-scale anonymised data sources available within the Secure Anonymised Information Linkage (SAIL) Databank.

Characteristics of the Outdoor Environment Affording Physical Activity, Motor Competence, and Social Interactions in Children Aged 3-7 Years: A Systematic Review.

Unlabelled: Early childhood education (ECE) settings play a crucial role in promoting physical and social development among children aged 3-7 years. This systematic review sought to examine the associations between characteristics of ECE outdoor environments, social interactions, physical activity, and motor competence. The secondary aim examines previously applied methods to capture children's behaviour in the context of their social and physical environment.

Phenotypic and genotypic landscape of antibiotic resistance through One Health approach in Sri Lanka: A systematic review.

Objectives: Antibiotic resistance (ABR) constitutes a significant burden to economies in developing countries. In the 'One-Health' concept, ABR in human, animals, and environment is interconnected. The aim of this study was to critically appraise literature on ABR in all three domains in One Health, within the Sri Lankan geographical context.

Evaluating the psychosocial experiences of participants in HIV cure research before, during, and after analytical treatment interruptions: A longitudinal qualitative study in the United States.

The lack of socio-behavioral research on stress and psychosocial experiences among research participants who undergo analytical treatment interruption (ATI) in HIV cure studies underscores a critical gap in cure science. Existing literature acknowledges mixed and potentially adverse mental health impacts of ATIs among trial participants, but empirical insights before, during, and after clinical studies are scarce. We used longitudinal in-depth interviews with 11 participants in HIV cure-related research to explore their experiences with stress, coping, and psychological well-being before, during, and after an ATI.

How do Psychological Factors Influence Disaster Preparedness? Evidence from Disaster-Stricken Mountainous Areas of China.

Objectives: Disaster preparedness plays a vital role in mitigating risks and strengthening resilience of local communities in rural areas. This study examines the linkage between psychological factors and 4 kinds of disaster preparedness intentions and explores the challenges in translating intentions into actions.

Methods: This study utilized survey data from 325 households in Chongqing, China, that are threatened by geological disasters.

Environmental exposure and cancer occurrence in dogs: a critical appraisal of evidence.

Cancer is a significant contributor to morbidity and mortality in humans and is also the leading cause of death in dogs. It is estimated that up to 20 % of human cancers can be explained by environmental exposures to carcinogens. It has been hypothesized that companion animals such as dogs could not only be a model for the complex pathogenic processes of human cancers, but also act as sentinels for environmental carcinogens due to their relative shorter longevity, spontaneous occurrence of tumours, and intimate relationship with our everyday environments.

The impact of exposure to phthalates in thyroid function of children and adolescents: a systematic review.

Phthalic acid esters, or phthalates, are plasticizers commonly used in the plastics industry and they are known for their endocrine-disrupting effects. Numerous epidemiological studies have been conducted to evaluate the effects of phthalate exposure on thyroid function, both in adults and children. However, there is still considerable debate surrounding this issue.

Antarctic Expeditions: A Systematic Review of the Physiological, Nutritional, Body Composition and Psychological Responses to Treks Across the Continental Ice.

Background: Antarctic expeditions, although supported by scientific knowledge, face various challenges, with little research conducted to explore the physical demands that explorers experience.

Objective: To summarise physiological, psychological, body composition and nutritional changes faced during trek expeditions in the Antarctic's continental portion.

Design: Systematic review.

Earth's most needed uncultivated aquatic prokaryotes.

Aquatic ecosystems house a significant fraction of Earth's biosphere, yet most prokaryotes inhabiting these environments remain uncultivated. While recently developed genome-resolved metagenomics and single-cell genomics techniques have underscored the immense genetic breadth and metabolic potential residing in uncultivated Bacteria and Archaea, cultivation of these microorganisms is required to study their physiology via genetic systems, confirm predicted biochemical pathways, exploit biotechnological potential, and accurately appraise nutrient turnover. Over the past two decades, the limitations of culture-independent investigations highlighted the importance of cultivation in bridging this vast knowledge gap.

Depoliticization of Violence: Critical Limits of Risk Environment Frameworks in Drug Use Research.

The risk environment framework (REF) is a widely-accepted tool in policy research related to drug use. Its prevalence warrants a critical exploration of its strengths and weaknesses. This critical appraisal is a comprehensive analysis of the REF by definition and through relevant examples of its use within the context of public health evaluations, social science research, and epidemiological strategies in substance use-related policy.

Challenge or threat? A Q-methodological study into nursing students' perceptions on learning to collaborate under stress.

Introduction: Nursing students will come across stressful situations during their internships and will continue to do so in future practice. Because of the impact stress can have on performance, nursing students need to be equipped to work and collaborate in such situations. Careful consideration of the needs and desires of nursing students should be taken in account, in order to create a training environment that fosters students' ability to learn to collaborate under stress.

Economic Evaluations of Worksite Health Centers: A Systematic Review.

Objective: To systematically review the cost-effectiveness or return on investment (ROI) from worksite health centers (WHCs) in the US.

Methods: We searched four databases and the grey literature for studies that conducted economic evaluation and provided economic outcomes of US-based WHCs. The quality and risk of bias were assessed using JBI Critical Appraisal Tools of Economic Evaluations.

Membrane fouling characteristics and cleaning strategies for rural decentralized nanofiltration drinking water station based on groundwater source.

Groundwater is an important source of drinking water in rural areas. In this study, the performance of water purificat ion in a rural water station equipped with nanofiltration (NF) membranes based groundwater source was investigated, as well as the contamination morphology, foulant composition and distribution characteristics of NF membrane. Results showed that significant differences of membrane foulants were observed in different sections of NF membrane.

Prooxidant state in anticancer drugs and prospect use of mitochondrial cofactors and anti-inflammatory agents in cancer prevention.

An extensive body of literature has associated cancer with redox imbalance and inflammatory conditions. Thus, several studies and current clinical practice have relied on the use of anticancer drugs known to be associated with prooxidant state. On the other hand, a number of studies have reported on the effects of several antioxidants, anti-inflammatory agents and of mitochondrial cofactors (also termed mitochondrial nutrients, MNs) in counteracting or slowing carcinogenesis, or in controlling cancer growth.

Spontaneous Emergence of Lipid Vesicles in a Coacervate-Based Compartmentalized System.

The spontaneous emergence of lipid vesicles in the absence of evolved biological machinery represents a major challenge for bottom-up synthetic biology. We show that coacervate microdroplets could create a compartmentalized environment that enriches lipid molecules and facilitates their spontaneous assembly into lipid vesicles. These vesicles can escape from the coacervate microdroplets in a continuous process under non-equilibrium conditions, resembling a constant production process akin to a "primitive enzyme" factory assembly line.

Patients' Experiences of Healthcare Professionals' Competence in Digital Counselling in Healthcare Settings-A Qualitative Systematic Review.

Aim: To critically appraise and synthesise qualitative evidence about patients' experiences of healthcare professionals' competence in digital counselling in healthcare settings.

Design: A qualitative systematic review.

Methods: The review followed the Joanna Briggs Institute methodology for systematic reviews of qualitative evidence.

Migrant students' self-reported executive function skills in relation to mental health, postmigration stress, and positive appraisals of self and the social context.

Refugee and non-refugee migrant youths may carry a double burden of past adversities and post-migration stress while trying to continue schooling and adapt to their new social and cultural environment. Executive functioning skills are central to learning and navigating in the new context. Knowledge of how young migrants' executive functioning is associated with stressful factors and positive or potentially protective factors, could contribute to understanding and possibly finding ways to support these young learners.