13 results match your criteria: "Appasaheb Birnale College of Pharmacy[Affiliation]"
Anal Sci
November 2023
Department of Pharmaceutics, Adarsh College of Pharmacy, Vita, Vita, Maharashtra, India.
The goal of the current work was to establish a simple, reproducible, and reliable UV spectrophotometric method for determining naringenin in phytosomal formulations. The solvent methanol was optimized and spectrophotometric analysis was carried out at 289 nm. The proposed method was also validated for linearity, specificity, accuracy, precision, ruggedness, and robustness in accordance with the International Council for Harmonisation (ICH).
View Article and Find Full Text PDFAAPS PharmSciTech
April 2023
Tatyasaheb Kore College of Pharmacy, Warananagar, Tal: Panhala, Dist , Kolhapur, Maharashtra, India, 416113.
Simvastatin (SMV) is noticed as a repurposed candidate to be effective against breast cancer (BC). However, poor solubility, dose-limiting toxicities, and side effects are critical hurdles in its use against BC. The above drawbacks necessitate the site-specific (localized) delivery of SMV via suitable nanocarriers.
View Article and Find Full Text PDFJ Control Release
January 2022
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai, Maharashtra, India, 400019.
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of cancer deaths throughout the world. The shortfall of affordable and effective first-line chemotherapeutics, the existence of resistant tumors, and the non-optimal route of administration contribute to poor prognosis and high mortality in LC. Administration of repurposed non-oncology drugs (RNODs) loaded in nanocarriers (NCs) via inhalation may prove as an effective alternative strategy to treat LC.
View Article and Find Full Text PDFCurr Drug Targets
September 2021
Department of Pharmaceutical Chemistry, Arvind Gavali College of Pharmacy, Satara Shivaji University, Satara- 415015, India.
Fluoroquinolones are one of the world's most valuable and popularly used categories of antimicrobial agents. This paper attempts to review the substantial progress of fluoroquinolones from their discovery to black box warning. Antibiotic drug choice will remain difficult in the presence of increasing resistance, but the introduction of fluoroquinolones has created a new and exciting era in antimicrobial treatment.
View Article and Find Full Text PDFComb Chem High Throughput Screen
October 2021
Departement of Pharmacy, Govt. College of Pharmacy, Karad, Maharashtra, India.
Unlabelled: The extracts and the compounds isolated from Phyllanthus amarus Schumm and Thonn (Family: Euphorbiaceae) have shown a wide spectrum of pharmacological activities including antiviral, antibacterial, antiplasmodial, antimalarial, antimicrobial, anticancer, antidiabetic, hypolipidemic, antioxidant, hepatoprotective, nephroprotective and diurectic properties.
Background: This investigation was aimed at exploring the anxiolytic potential of Phyllanthus amarus standardized extracts and predict probable role of marker phyto constitutents.
Objective And Methods: Three standardized extracts of Phyllanthus amarus plant viz.
Iran J Pharm Res
January 2018
Department of Chemistry, Rajarambapu College of Pharmacy, Kasegaon Maharastra, India.
Tuberculosis still remains a leading cause of death in the world. Currently considerable interest in natural products and their derivatives in the area of drug research for multidrug resistant tuberculosis (MDR-TB). The present investigation focused on identification, isolation, characterization of lead constituents and to determine the antitubercular activity of their enriched fractions and isolated compounds by Nitrate reductase assay (NRA) method.
View Article and Find Full Text PDFJ Microencapsul
June 2018
b Department of Pharmaceutics , Bharati Vidyapeeth College of Pharmacy, Kolhapur , India.
An objective of the present study was to prepare colon-specific microspheres of curcumin (CUR) containing ascorbic acid (AA) for improved oral bioavailability. 3 factorial design was used to optimise chitosan microspheres (CSMS) containing CUR and AA. Subsequently, optimised CSMS were coated with Eudragit S-100, for delivery to colon.
View Article and Find Full Text PDFJ Tradit Complement Med
October 2018
Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur 416013, Maharashtra, India.
Objective: The rhizome of Tectaria cicutaria has been used in Indian traditional medicine for the treatment of various disorders. The objective of present investigation is to screen various extracts of the rhizomes of for anti-cancer activity and to investigate the mechanism involved.
Materials And Methods: The rhizomes of were extracted with different solvents.
J Ayurveda Integr Med
November 2015
Department of Appasaheb Birnale College of Pharmacy, Sangli, India.
Background: Vetiveria zizanioides (VZ) (family: Poaceae), an aromatic plant commonly known as "Vetiver" has been used for various ailments. Concerning the various ailments being listed as the traditional uses of VZ, no mention about anxiety and memory was found.
Objective: The present study examined the anxiolytic and memory enhancing activity of ethanolic extract of V.
Pharmacol Rep
June 2014
Department of Pharmacology, Appasaheb Birnale College of Pharmacy, India.
Background: Previous studies have shown that unilateral injection of carrageenan into the gastrocnemius muscle produces chronic thermal and mechanical hyperalgesia.
Aim: In the present study, we have characterized this model of muscoskeletal inflammatory pain, by evaluating the antihyperalgesic effects of selective and non-selective COX-2 inhibitors after systemic administration.
Materials And Methods: Rats were injected with 3% carrageenan in the left gastrocnemius muscle and hyperalgesia to heat stimuli (measured as decreased withdrawal latency) to paws was assessed before and at varying times after injection, till end of 2nd week.
Food Chem
May 2012
Department of Biochemistry, Shivaji University, Kolhapur, Maharashtra 416004, India. Electronic address:
Foeniculum vulgare fruits are routinely consumed for their carminative and mouth freshening effect. The plant was evaluated for aldose reductase inhibition and anti-diabetic action. Bioguided fractionation using silica gel column chromatography, HPLC, and GC-MS analysis revealed trans-anethole as the bioactive constituent possessing potent aldose reductase inhibitory action, with an IC50 value of 3.
View Article and Find Full Text PDFIndian J Pharmacol
March 2012
Department of Pharmacology, Appasaheb Birnale College of Pharmacy, Sangli, Maharashtra, India.
Objectives: To investigate the effect of methanolic extract of Ixora coccinea Linn. (MEIC) leaves against doxorubicin-induced cardiac toxicity in rats.
Material And Methods: Albino Wistar rats were pretreated with the methanolic extract of Ixora coccinea Linn.
Iran J Pharm Res
December 2013
Appasaheb Birnale College of Pharmacy, Sangli, India.
A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation.
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