277 results match your criteria: "Apocrine Hidrocystoma"

In this case report, we demonstrate a rare co-occurrence of multiple eyelid apocrine hidrocystomas with a prolactinoma.

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Background/objectives: Hidrocystomas, eccrine and apocrine, are rare cystic lesions that form benign tumors of the sweat glands. This study aimed to describe the clinical features of hidrocystomas and evaluate the role of non-invasive imaging techniques, including dermoscopy, Line-field Confocal Optical Coherence Tomography (LC-OCT), Reflectance Confocal Microscopy (RCM), and Ultra-High-Frequency Ultrasound (UHFUS), in their diagnosis.

Methods: In total, seven cases of hidrocystomas were collected from the Dermatologic Clinic of the University of Siena, Italy.

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Article Synopsis
  • Tumor collisions, a rare occurrence with a 0.0017% incidence rate, often involve seborrheic keratosis, melanocytic nevi, and basal cell carcinoma (BCC), and are generally considered incidental events.
  • A retrospective study was conducted analyzing hospital records to identify collisions between BCCs or squamous cell carcinoma (SCC) and apocrine-sebaceous-follicular unit (ASFu) neoplasms from 2005 to 2017.
  • The study identified 12 collision cases involving BCC and ASFu tumors, primarily in immunosuppressed patients, with many neoplasms located beneath the BCC, leading to new insights and hypotheses about these tumor interactions
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Article Synopsis
  • The study focuses on a case of conjunctival apocrine hidrocystoma that developed 60 years after a strabismus surgery in a 71-year-old man, highlighting its clinical features.
  • The cystic lesion was diagnosed through surgical excision, revealing characteristic cell structures associated with apocrine hidrocystomas, and a review of seven similar cases found that all presented after age 50.
  • The findings suggest that previous trauma or surgery, like strabismus surgery, might lead to the development of apocrine hidrocystomas due to ectopic gland deposition.
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Article Synopsis
  • Apocrine hidrocystomas are non-cancerous cysts that develop from the apocrine sweat glands and usually appear on the head and neck, particularly around the eyes.
  • * They can also occur in other areas like the armpits, nipples, and ears, but these sites are less common.
  • * The article highlights a rare case of a hidrocystoma found in the nail bed of a 55-year-old woman, which has not been documented in prior medical literature.*
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Article Synopsis
  • Hidrocystomas are infrequent benign cystic tumors originating from sweat glands, and this case is unique as it involves the nasolacrimal duct, which has not been previously reported.
  • A 28-year-old woman with no major medical history had a growing mass near her right lower eyelid for two years, leading to a CT scan that revealed soft tissue in the nasolacrimal duct.
  • After surgically removing the cyst, the histopathological examination confirmed it was an apocrine hidrocystoma, highlighting its rarity.
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Peri-ocular proliferative apocrine hidrocystoma (cystadenoma): A clinicopathological case series.

Int J Surg Case Rep

January 2024

Ophthalmology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia; King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia; Pathology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia. Electronic address:

Article Synopsis
  • - Apocrine cystadenomas are uncommon benign tumors that can develop near the eyes, originating from glands of Moll, and are identifiable by specific histopathological features that set them apart from similar conditions like hidrocystomas.
  • - A study analyzed four male patients aged 20 to 62, all initially misdiagnosed with hidrocystomas; upon surgical removal, histopathological evaluations confirmed apocrine cystadenomas without atypical or infiltrative traits.
  • - These cysts can be mistaken for other skin lesions, particularly in the eyelid area, highlighting the need for awareness among ophthalmologists and recommending further research into their characteristics.
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Article Synopsis
  • Apocrine cystadenoma is a rare, benign cystic tumor with unclear origins, linked to long-term apocrine hidrocystomas, and primarily occurs on the scalp of older adults.
  • A study analyzed 13 cases revealing they typically presented as slow-growing, multilocular lesions with distinct dermatoscopic features, including a range of colors and prominent peripheral vessels.
  • Histologically, the tumors displayed a mix of nonproliferative apocrine lining and proliferative adenomatous components, with specific immunohistochemical staining patterns noted, but findings are limited by the study's single-institution, retrospective design.
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Article Synopsis
  • Two cases of orbital hidrocystoma are reported, highlighting clinical features and management strategies for an enlarging orbital mass.
  • One patient was a 48-year-old man with a mass near the supraorbital area, and the other was a 70-year-old man with a lesion near the lacrimal gland; both diagnoses were confirmed as apocrine hidrocystomas through histopathology.
  • Post-surgery, mild nerve sensation loss in the first patient resolved quickly, and no recurrences were observed in either case during follow-up; these findings suggest that apocrine hidrocystomas, though rare in the orbit, should be included in the differential diagnosis for similar cystic masses.
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Article Synopsis
  • - A child was diagnosed with a rare type of skin cyst called pericanalicular eccrine hidrocystoma located on the upper eyelid.
  • - The child underwent surgical removal of the cyst along with repair of the affected canalicular area.
  • - The surgery was successful, leading to a positive outcome for the child.
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Nipple apocrine hidrocystoma in a male adolescent: A rare lesion site.

Asian J Surg

December 2023

Division of Pediatric Surgery, Department of Surgery, Taichung Veterans General Hospital, No. 1650, Sec. 4, Taiwan Boulevard, Situn District, Taichung City, 407219, Taiwan.

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Article Synopsis
  • The study investigates the relationship between the presence of neuroendocrine marker INSM1 in cutaneous mucinous sweat gland carcinoma and its implications for patient prognosis, based on newly developed staining techniques.
  • Out of 12 adenocarcinoma cases, most mucinous types were found to express INSM1, which was associated with lower risk of metastasis, while nonmucinous cases showed higher potential for lymph node involvement.
  • The findings suggest that routine testing for INSM1 in skin tumors could improve patient screening and follow-up, as those with neuroendocrine tumors may have different cancer risks compared to non-neuroendocrine types.
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Article Synopsis
  • A 51-year-old Japanese woman had translucent papules on her face that worsened over five years, diagnosed as multiple apocrine hidrocystomas.
  • To relieve her symptoms that affected her vision, she had surgery to remove some tumors on her lower eyelids, which successfully improved her eyesight.
  • About 1.5 years later, she received carbon dioxide fractional laser therapy for remaining lesions, showing improved symptoms and good cosmetic outcomes, though minor scarring and color changes were noted.
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Unusual location of apocrine hidrocystoma in children: Case series.

Int J Surg Case Rep

July 2023

Pediatric Surgery Unit, Department of Woman, Child, General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy. Electronic address:

Article Synopsis
  • Apocrine Hidrocystoma is a rare benign tumor that arises from the apocrine sweat glands, particularly in the head and neck, and this case series focuses on children with tumors located in the urogenital area.
  • Four boys, ages 9 to 17, presented with cystic masses, leading them to require surgical intervention due to aesthetic concerns or issues with urination.
  • The study concludes that surgery is the main treatment option with a low chance of the tumor returning afterward.
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Article Synopsis
  • * The analysis revealed a cystic tumor filled with mucin and characteristic secretion patterns, with specific immunohistochemical markers indicating its apocrine nature.
  • * This case is notable as it represents the fourth documented occurrence of an eyelid apocrine cystadenoma in medical literature, and the tumor showed very low cell proliferation.
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Article Synopsis
  • Mucinous metaplasia, specifically the goblet cell type, is extremely rare in the skin, and this case report discusses the second occurrence involving an apocrine papillary hidrocystoma.
  • The patient, an elderly man, presented with a blue-pigmented nodule on his scalp, which was found to be histologically composed of cystic structures with goblet cells and papillary formation.
  • Most instances of this type of metaplasia have been noted in genital skin after chronic inflammation, but this case illustrates its occurrence in nongenital skin, emphasizing differences in histological features compared to typical apocrine glands.
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Article Synopsis
  • - Syringocystadenoma papilliferum (SCAP) and apocrine hidrocystoma (AH) are benign skin tumors that usually occur separately, with SCAP found mainly on the head and neck and AH in the periorbital area.
  • - A 68-year-old male presented with a painless red nodule on his back, which upon histological examination revealed features of both SCAP and AH within a single lesion.
  • - Despite being advised to remove the lesion after a biopsy, the patient chose not to pursue additional surgical treatment, marking a rare case of a complex apocrine tumor in an unusual location.
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Median raphe cysts: A clinico-pathologic and immunohistochemical study of 52 cases.

J Cutan Pathol

June 2023

Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

Article Synopsis
  • - Median raphe cysts (MRC) are non-communicating cystic lesions in the genital area, showing positivity for various immunohistochemical markers including CK5-6, CK7, and p63.
  • - A study of 52 patients over 26 years employed monoclonal antibodies to investigate these markers, revealing significant expression of GATA3 and CK7 among the cases.
  • - Findings suggest MRC may originate from urothelial cells, and no significant differences were observed between HMFG1 expression in MRC and apocrine hidrocystomas.
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Orbital apocrine hidrocystoma with ptosis.

Am J Ophthalmol Case Rep

December 2022

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, USA.

Purpose: To describe a patient with orbital apocrine hidrocystoma presenting with ptosis and subsequent management.

Observations: A 43-year-old woman presented to the oculoplastic surgery clinic with a left-sided ptosis and enlarging but painless mass in the sulcus of the left upper eyelid. Magnetic resonance imaging demonstrated a large, circumscribed T2 bright cystic lesion in the extraconal space.

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