12,341 results match your criteria: "Aortic Coarctation"

Pinning down the accuracy of physics-informed neural networks under laminar and turbulent-like aortic blood flow conditions.

Comput Biol Med

December 2024

Department of Electrical, Computer and Biomedical Engineering, Toronto Metropolitan University, 350 Victoria Street, Toronto, M5B 2K3, Canada. Electronic address:

Background: Physics-informed neural networks (PINNs) are increasingly being used to model cardiovascular blood flow. The accuracy of PINNs is dependent on flow complexity and could deteriorate in the presence of highly-dynamical blood flow conditions, but the extent of this relationship is currently unknown. Therefore, we investigated the accuracy and performance of PINNs under a range of blood flow conditions, from laminar to turbulent-like flows.

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Immediate Use of Impella CP for High-Risk Percutaneous Coronary Intervention After Repair of Thrombosed Aortic Coarctation.

Catheter Cardiovasc Interv

December 2024

Interventional Cardiology Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.

Aortic coarctation represents up to 7% of congenital heart diseases and is associated with hypertension and coronary artery disease, which continues to be the leading cause of death even after successful surgical repair. However, there is limited knowledge of managing both conditions, especially in the setting of an acute coronary syndrome. We herein present the case of a 53-year-old man with a history of hypertension who initially presented with an ST-elevation myocardial infarction successfully treated with thrombolysis and hemodynamic compromise.

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Introduction And Clinical Importance: Shone complex (SC) is a rare multilevel congenital heart disease (CHD) characterized by four left-sided heart obstructive lesions: parachute mitral valve, supravalvular mitral ring, subaortic stenosis, and coarctation of the aorta (CoA), accounting for 0.6-0.7 % of CHD cases.

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The global effect of aortic coarctation on carotid and renal pulsatile hemodynamics.

PLoS One

December 2024

Department of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, California, United States of America.

Coarctation of the aorta (CoA) is a congenital disease characterized by the narrowing of the aorta, typically the descending portion after the left subclavian artery. If left untreated, by the time individuals reach 50 years of age, the mortality rate can reach 90%. Previous studies have highlighted the adverse effects of CoA on local hemodynamics.

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Background: Aortic arch obstruction and/or coarctation of aorta is uncommon (5-20%) in balanced atrioventricular septal defects. Although technically challenging, prenatal diagnosis of aortic arch obstruction in atrioventricular septal defect is critical for delivery planning and improves prenatal counselling regarding the timing of cardiac surgery. We sought to identify prenatal predictors of coarctation of aorta in atrioventricular septal defect.

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Objectives: The bicuspid aortic valve (BAV) is the most common congenital heart defect. Patients with BAV frequently develop aortopathy, which depends on the dysfunction and morphotype of the BAV.

Aim: The aim of our study was to compare the echocardiography and cardiac magnetic resonance (CMR) findings in BAV patients, and to define the risks of BAV dysfunction and aortopathy.

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Background: Congenital heart defects (CHD) being the most common congenital malformation, significantly impact mortality and morbidity in children and adults. Early detection greatly improves treatment and prognosis. Routine pulse oximetry screening and fetal echocardiography in Germany have advanced early CHD diagnosis.

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Repair of aortic coarctation in neonates less than two kilograms.

Interdiscip Cardiovasc Thorac Surg

December 2024

Department of Cardiac Surgery, Bristol Royal Hospital for Children, University of Bristol, Bristol, UK.

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Role of stimulated by retinoic acid 6 in 46 children of coarctation of the aorta.

Heliyon

December 2024

National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, PR China.

(1) ObjectiveCoarctation of the aorta (CoA) is a complex congenital heart disease. Research on differential genes in patients with CoA and other groups of aortas and investigating the pathogenesis of aorta coarctation is essential for prevention and diagnosis. This study was conducted between January 2019 and December 2021.

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Reliability of 4D Flow MRI for Investigation of Fetal Cardiovascular Hemodynamics in the Third Trimester.

Radiol Cardiothorac Imaging

December 2024

From the Departments of Radiology (E.K.E., T.F., M.L.M., L.P.B., A.J.B.), Pediatrics-Cardiology (R.M.F.), and Bioengineering (A.J.B.), University of Colorado Anschutz Medical Campus, 13123 E 16th Ave B125, Aurora, CO 80045; and Department of Radiology, Children's Hospital Colorado, Aurora, Colo (S.A.S., A.J.B.).

Article Synopsis
  • The study aimed to establish reference values for fetal 4D flow MRI and assess its reliability in measuring blood flow in healthy fetuses and those with suspected aortic coarctation (CoA).
  • Researchers conducted MRI scans on 34 pregnant patients, collecting data from both healthy fetuses and those with potential cardiovascular issues, analyzing the accuracy and consistency of the flow measurements obtained.
  • The results indicated that fetal 4D flow MRI provides reliable hemodynamic measurements with high precision and repeatability, although it tends to underestimate blood flow compared to traditional 2D phase contrast MRI techniques.
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Successful Treatment of Aortic Coarctation in an Extremely Low Birth Weight Infant with Balloon Angioplasty.

Z Geburtshilfe Neonatol

December 2024

Pediatric Cardiology, TC Sağlık Bakanlığı Ankara Etlik Şehir Hastanesi, Ankara, Turkey.

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Aortic uncrossing for right circumflex aorta with coarctation and arch hypoplasia in a neonate.

J Thorac Cardiovasc Surg

November 2024

Department of Cardiothoracic Surgery, University of Louisville School of Medicine, Norton Children's Hospital, Louisville, Ky.

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Article Synopsis
  • - This study investigated aortic valve disease in adults with repaired coarctation of the aorta, focusing on differences between male and female patients regarding cardiac condition and symptoms.
  • - Despite similar baseline conditions for aortic valve disease in both sexes, female patients exhibited more severe heart-related changes and a quicker onset of symptoms.
  • - While female patients faced greater cardiac remodelling and symptom development, the overall likelihood of undergoing aortic valve replacement (AVR) was comparable between genders.
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Long-Term Results of Transcatheter Intervention of Coarctation of the Aorta: A 12-Year Single-Center Experience.

Am J Cardiol

November 2024

Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

Article Synopsis
  • * A study analyzed the outcomes of 103 patients (aged 21 days to 63 years) who underwent transcatheter intervention for CoA over a 12-year span, focusing on clinical and echocardiographic data.
  • * Results showed significant improvements, including lower systolic blood pressure and reduced left ventricular mass, with a high survival rate of 98.1% and minimal need for reintervention, supporting the efficacy of the treatment and innovative techniques used.
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Article Synopsis
  • Mycotic aneurysms are localized expansions of blood vessels caused by infections that weaken the vessel walls, making them serious but rare medical conditions.
  • They can arise from bacteria invading healthy blood vessels or infecting existing abnormalities like aneurysms or plaques.
  • The case of a four-year-old with an abdominal aortic mycotic aneurysm and pericarditis highlights the diagnostic challenges due to non-specific symptoms, along with a discussion on risk factors and treatment options.
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Aortic Pseudodissection After Stenting of Coarctation of the Aorta.

JACC Cardiovasc Interv

October 2024

Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada. Electronic address:

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Article Synopsis
  • * Four patients with congenital heart conditions successfully underwent IVL-assisted procedures such as stenting and valve replacement, with no major complications reported.
  • * IVL can help in the implantation and dilation of stents in severely calcified vascular conduits; however, caution is advised due to the risk of vascular injury, suggesting consideration of covered stents before extensive dilation.
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Berry syndrome: First Successful neonatal single-stage repair in India.

Ann Pediatr Cardiol

October 2024

Department of Pediatric Cardiology, Medanta-The Medicity, Gurgaon, Haryana, India.

Article Synopsis
  • Berry syndrome involves a combination of rare cardiovascular conditions, including a distal aortopulmonary window and aortic origin of the right pulmonary artery.
  • The text discusses the first neonatal case of single-stage repair of Berry syndrome in India, highlighting its significance.
  • Successful short-term and long-term outcomes are attributed to timely surgical intervention and skilled postoperative care, with a preference for single-stage repair when possible.
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  • * A 22-year-old patient who had undergone bypass surgery for aortic coarctation developed a pseudoaneurysm 30 years later, prompting treatment with total arch replacement using a frozen elephant trunk technique.
  • * The use of the frozen elephant trunk approach for revising aortic surgeries can be an effective and suitable option based on individual patient needs.
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Article Synopsis
  • Ascending-to-descending aortic bypass is a repair method for complex aortic coarctation, showing low early complications, but long-term results were previously unclear.
  • A study of 81 patients who had the procedure from 1985 to 2012 revealed 5, 10, and 20-year survival rates of 94%, 90%, and 85%, with no perioperative deaths and no significant complications related to the bypass.
  • Overall, this technique is considered safe with excellent long-term outcomes, improving systemic hypertension, and does not interfere with future surgeries through the same chest incision.
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Giant cell aortitis combined with arteritis and coarctation of the aorta in 3.5-month child: A case report and literature review.

Cardiovasc Pathol

November 2024

Department of Pathology and Forensic Medicine, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, Lviv, 69, Pekarska str., 79010. Electronic address:

Article Synopsis
  • The case details a rare instance of giant cell aortitis (GGA) combined with aortic coarctation in a 3.5-month-old girl, showcasing its uniqueness in medical literature.
  • The infant experienced severe symptoms following a viral infection, leading to multiple organ failure and death just 20 hours after hospitalization.
  • Pathological examinations revealed significant inflammation and structural abnormalities in the aorta and its branches, marking this case as the youngest documented patient with this rare combination of conditions.
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Article Synopsis
  • The study focuses on comparing two surgical techniques—sternotomy and thoracotomy—for treating aortic coarctation, aiming to find an effective approach that minimizes complications and avoids recoarctation.
  • 103 procedures were divided between the two techniques, with a matching analysis of 25 patients from each group to ensure fair comparison.
  • Results showed similar mortality rates and early complications for both methods, but the sternotomy approach indicated a lower rate of recoarctation, suggesting it might be the preferred option for surgical repair.
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