707 results match your criteria: "Aortic Center[Affiliation]"

Fenestrated Anaconda Endograft for the Treatment of Complex Aortic Aneurysms: Systematic Review and Meta-Analysis.

J Endovasc Ther

January 2025

Department of Vascular Surgery, Swiss Aortic Center Bern, Inselspital, University Hospital of Bern, University of Bern, Bern, Switzerland.

Purpose: To perform a systematic review and meta-analysis of the outcomes of Anaconda fenestrated endograft for the treatment of complex abdominal aortic aneurysms (cAAA).

Material And Methods: A systematic search of all the literature reported until May 2024 was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The pooled 30-day mortality rate, technical success rate, reintervention rate as well as bridging stent occlusion rate, and corresponding 95% confidence intervals (CIs) were estimated using fixed or random effect methods.

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Hybrid Arch Aneurysm Repair With Ascending Aortic Wrap and TEVAR.

J Endovasc Ther

January 2025

Aortic Center, Hôpital Marie-Lannelongue, Groupe Hospitalier Paris Saint Joseph, Université Paris-Saclay, INSERM UMR_S 999, Le Plessis Robinson, France.

Introduction: Management of patients with large aortic arch aneurysms who are considered high risk for frozen elephant trunk technique have been challenging, especially when they have a dilated ascending aorta (AA) that precludes total endovascular branched repair (arch BEVAR). A viable option in our armamentarium is wrapping of the AA (AW), and zone 0 Ishimaru TEVAR.

Methods: Retrospective analysis of our aortic database from 2013 to 2024 to select high-risk patients with aortic arch aneurysm that had an AW and TEVAR.

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Delayed surgical management of an Amplatzer device migration into the aortoiliac bifurcation.

J Vasc Surg Cases Innov Tech

February 2025

Department of Vascular Surgery, Aortic Center, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, INSERM UMR_S 999, Université Paris Saclay, Paris, France.

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Twenty-Year Results of Open Surgical Suprarenal Aortic Fenestration for Acute Complicated Type B Aortic Dissection.

Ann Vasc Surg

December 2024

Department of Interventional Radiology, Semmelweis University, Budapest, Hungary; Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, Budapest, Hungary. Electronic address:

Background: Open surgical suprarenal aortic fenestration (OSSAF) is a technique to treat complicated type B aortic dissection (cTBAD) by resecting the intimal membrane at the level of the visceral arteries. This invasive procedure is largely abandoned since the advent of thoracic endovascular aortic repair (TEVAR), which has become the gold standard for treating cTBAD. Identifying patterns in the late history of patients who underwent OSSAF might help better understand the evolution of type B aortic dissection (TBAD).

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Is Connective Tissue Disorder a Risk Factor for Durability after Valve-Sparing Root Replacement?

Semin Thorac Cardiovasc Surg

December 2024

Aortic Center, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address:

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Impact of arch disease pathology on outcomes of zone 0 branched thoracic endovascular arch repair.

J Vasc Surg

December 2024

Department of Cardiac and Vascular Surgery, Aortic Center, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, INSERM UMR_S 999, Université Paris Saclay, Le Plessis-Robinson, France. Electronic address:

Article Synopsis
  • Z0BTEVAR is a minimally invasive procedure for repairing aortic arch issues in high-risk patients, focusing on chronic aortic dissection (C-AD) versus non-aortic dissection (N-AD) cases.
  • A study involving 213 patients found that N-AD patients had a higher rate of in-hospital complications, including mortality and stroke, compared to those with C-AD, highlighting the impact of disease type on outcomes.
  • The findings suggest that while Z0BTEVAR offers viable outcomes, careful patient selection and techniques to reduce stroke risks are crucial for improving post-operative results.
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Modified-Bentall Single-Patch Konno Enlargement Technique for Aortic Stenosis and Prosthesis-Patient Mismatch.

Ann Thorac Surg

December 2024

Department of Thoracic and Cardiovascular Surgery, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio; Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland Clinic, Cleveland, Ohio.

Article Synopsis
  • The BeSPoKE technique is a surgical method used to enlarge the aortic outflow tract in adults with complex heart issues, specifically those facing aortic stenosis and prosthesis-patient mismatch.
  • A study involving 25 adults showed significant improvement in aortic valve gradients post-surgery, with a median size increase of the prosthesis and no reports of operative mortality.
  • Postoperative complications included atrial fibrillation and heart block, but overall survival at two years was high at 92%, indicating that this technique is a safe and effective option for patients with small left ventricular outflow tracts.
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Article Synopsis
  • The physician-modified endograft technique is gaining popularity as a viable option to traditional fenestrated endovascular aortic repair.
  • A new workflow incorporating a bifurcation endograft, punch card, and Hungaroring reinforcement was tested on 11 patients with 43 vessels and showed a 100% clinical success rate.
  • No major complications or deaths occurred within 30 days, suggesting these innovative methods may enhance repair safety and durability.
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Article Synopsis
  • - The study evaluated the early and mid-term results of using a physician-modified candy-plug (pmCP) technique for occluding false lumen in patients with type-B aortic dissection, involving analysis of 17 patients treated between September 2018 and May 2024.
  • - Results showed a 100% technical success rate, an 82% clinical success rate, and a low postoperative mortality of 6%. Notably, 82% of patients achieved early complete false lumen occlusion.
  • - The pmCP technique demonstrated promising long-term outcomes with 75% of patients experiencing complete thoracic false lumen thrombosis and stable aneurysm sizes during follow-up, indicating reduced need for further aortic interventions. *
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Background: This study aimed to evaluate the suitability of a coronary-branched ascending aortic endograft, paired with aortic valve (AV) prosthesis (Endo-Bentall), for the endovascular repair of ascending aortic aneurysms.

Methods: Preoperative ≤1 mm computed tomography angiographies of consecutive patients managed with Bentall procedure or ascending aortic replacement and AV reconstruction/replacement, in a single institution (from January 1, 2008, to December 31, 2023), were retrospectively analyzed. Dedicate software was used to assess (1) vascular access, (2) proximal landing zone, (3) coronary artery anatomy, and (4) distal landing.

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Article Synopsis
  • Pharmacological inhibition of megalin in mice helps reduce atherosclerosis, but the study aimed to see if specifically deleting megalin in renal proximal tubule cells (PTCs) could have similar effects against hypercholesterolemia-induced atherosclerosis.
  • The experiments involved creating mice with and without megalin (PTC-LRP2 -/-) and inducing atherosclerosis by using a Western diet, but results showed that deleting megalin did not reduce atherosclerosis in any mice.
  • Instead, male PTC-LRP2 -/- mice exhibited severe kidney issues, including CD68+ cell infiltration and tubular atrophy, indicating that high-fat diets can lead to kidney damage independent of cholesterol levels, while female P
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: Vascular access site complications (VASCs) after endovascular interventions requiring a large-bore access are frequent and known to be associated with increased morbidity and mortality. Although balloon-expandable covered stents (BECSs) are increasingly used in such indications, their performance in this rather hostile territory is currently unknown. We aimed to evaluate the safety and efficacy of BECSs in common femoral artery (CFA) VASCs management.

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Objectives: The goal of this project was to assess the efficacy of a reoperative frozen elephant trunk (FET) operation for treating residual type A aortic dissections.

Methods: Between April 2015 and October 2023, a total of 237 patients underwent elective redo surgical aortic arch replacement via the FET technique to treat residual type A aortic dissection in 11 European aortic centres. Data were pooled and analysed retrospectively.

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Purpose: The purpose of this study was to collect all the available evidence concerning technical success and early and mid-term clinical outcomes of physician-modified endografts (PMEGs) for the treatment of aortic arch pathologies in zones 0 to 2.

Material And Methods: We performed a systematic review to identify all the eligible studies that reported outcomes to the PMEGs for aortic arch pathologies in zones 0 to 2 and then conducted a qualitative synthesis and meta-analysis of the results. The main outcomes were technical success, mortality, stroke rate, bridging stents' complications, and reintervention rate.

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Thoracic endovascular aortic repair has become the first-line treatment modality for descending thoracic aortic diseases. Coverage of the aortic arch branches is often required to extend the proximal seal zones during thoracic endovascular aortic repair. The thoracic branch endoprosthesis (TBE) is the first US Food and Drug Administration-approved branched device for thoracic endovascular repair allowing for incorporation of the left subclavian artery.

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The Thoracoabdominal Multibranch Endoprosthesis (TAMBE) is a commercially available off-the-shelf four-vessel inner branched endograft for complex abdominal and thoracoabdominal aortic aneurysms. As post-dissection thoracoabdominal aortic aneurysms (PD-TAAAs) were excluded from the pivotal trials, there is paucity of data on the use of TAMBE in PD-TAAAs. Here, we present a case demonstrating the feasibility of TAMBE in conjunction with iliac branch endoprosthesis to repair PD-TAAAs, with focus on the deployment technique specific to PD-TAAAs.

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Infliximab versus Cyclophosphamide for Severe Behçet's Syndrome.

NEJM Evid

November 2024

Department of Internal Medicine and Clinical Immunology, Sorbonne Universités, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière University Hospital, Centre national de références Maladies Autoimmunes et systémiques rares, National Reference Centre for Rare Autoinflammatory Diseases and Inflammatory Amyloidosis, INSERM, UMR S959, Immunology-Immunopathology-Immunotherapy, Paris.

Article Synopsis
  • A study compared the effectiveness and safety of infliximab and cyclophosphamide as induction therapies for severe Behçet's syndrome involving major vascular or CNS issues.
  • Infliximab showed a higher complete response rate (81%) compared to cyclophosphamide (56%), indicating it may be more effective.
  • Additionally, infliximab had fewer adverse events (29.6%) compared to cyclophosphamide (64%), suggesting it may also be safer for patients.
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Tabular review of contemporary open surgical repair experiences for treatment of thoracoabdominal aortic aneurysms.

J Cardiovasc Surg (Torino)

October 2024

Advanced Aortic Research Program, Department of Cardiothoracic and Vascular Surgery, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX, USA -

Open surgical repair of thoracoabdominal aortic aneurysms (TAAAs) is one of the most challenging operations due to extensive surgical dissection and exposure, risk of complications and need for reconstruction of the aorta and its branches. In the last two decades, endovascular techniques have evolved and now are considered a viable alternative to open surgical repair in patients with suitable anatomy. Regardless of which technique is selected, open or endovascular, reduction of postoperative morbidity and mortality requires large clinical volume, optimal patient selection and a multidisciplinary team that can take care of the surgical, anesthetic, critical care and postoperative issues that occur after these operations.

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Progressive Understanding of Aortic Disease.

Circulation

October 2024

Aortic Center, Department of Vascular Surgery, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, Université Paris Saclay, Le Plessis-Robinson, France (S.H.).

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Midterm single-center results with the use of custom-made endografts with inner branches, a call for attention.

J Vasc Surg

February 2025

Department of Vascular Medicine, German Aortic Center Hamburg, University Heart and Vascular Center UKE Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Article Synopsis
  • The study aimed to assess the effectiveness and safety of bridging covered stents (BCS) connected to inner branches of custom-made thoracoabdominal endografts during endovascular aortic repair procedures.
  • Conducted between 2019-2022, it involved 69 patients, reporting a high technical success rate of 99%, but also noted a 23% complication rate and 9% perioperative mortality.
  • Follow-up results showed varying rates of stent occlusion, with 6% for visceral and 14% for renal BCS, and identified misalignment of the target vessel ostium and the infrarenal aortic angle as significant factors influencing renal BCS
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Objectives: The aim of the study was to investigate the safety and feasibility of branched endovascular arch repair (b-TEVAR) with a custom-made double or triple inner branched arch endograft using a short dilator tip (35 mm) in patients with aortic arch pathologies.

Methods: Retrospective analysis of all consecutive patients undergoing b-TEVAR with a short dilator tip for the treatment of aortic arch pathologies in a high-volume tertiary center between January 2019 and July 2023. The combined primary endpoint was technical success and perioperative complications caused by the endograft, including tip-induced cardiac injury and trackability issues.

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Article Synopsis
  • A study analyzing the surgical treatment of aortoesophageal fistula (AEF) from 2020 to 2021 in Japan revealed that 61% of cases were secondary AEF, often arising from previous aortic surgeries.
  • Among 123 patients, the operative mortality rate was 18.7%, with significant factors contributing to mortality including postoperative complications like bleeding, stroke, and pneumonia.
  • The findings highlight the need for improved treatment strategies for AEF, as both surgical methods (open repair and TEVAR) were linked to high mortality rates and specific risk factors like dyslipidemia.
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