Association of Triglyceride-Glucose Index, Triglyceride to High-Density Lipoprotein Cholesterol Ratio, and Related Parameters With Prehypertension and Hypertension.

The objective of this study was to investigate the association between triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-c), triglyceride-glucose index (TyG), and related parameters (TyG-BMI, TyG-WC) with prehypertension and hypertension over 45 years old. According to the blood pressure diagnosis, the enrolled individuals were divided into two groups, which were prehypertension and hypertension. In multivariate logistic regression analysis, after adjusting for confounders, the highest quartile groups of TG/HDL-c, TyG, and related parameters showed a significantly increased risk of hypertension compared to the lowest quartile groups, and there was associated with hypertension when comparing the highest TG/HDL-c to the lowest TG/HDL-c and corresponding ORs were 1.

Panax Quinquefolium Saponins enhances angiogenesis in rats with diabetes and myocardial infarction.

Ethnopharmacological Relevance: Xi Yang Shen (Panax quinquefolium L.) was originally recorded in "Ben Cao Cong Xin" edited by Wu Yiluo during the Qing Dynasty. Panax Quinquefolium Saponins (PQS) is the main component derived from Panax quinquefolium L, and has been wildly used in the treatment of coronary heart disease.

[Current status of the clinical practice and analysis on the ratioanl prescription of antiarrhythmic drugs in Chinese patients with atrial fibrillation: Results from the Chinese Atrial Fibrillation Registry (CAFR) trial].

To explore the practice patterns and the related factors of oral antiarrhythmic drug (AAD) treatment in Chinese patients with atrial fibrillation (AF), and to evaluate the compliance of AAD application to atrial fibrillation management guidelines. From August 2011 to August 2016, medical records from 18 014 patients with AF were analyzed based on data from the Chinese Atrial Fibrillation Registry trial. Patients were divided into AAD group (7 788 cases, 43.

[Comparison of safety between continued warfarin therapy and bridging anticoagulation therapy in patients undergoing coronary intervention].

To compare the safety of continued warfarin therapy and bridging anticoagulation therapy during hospital stay in patients undergoing percutaneous coronary intervention (PCI). We retrospectively analyzed patients on warfarin therapy referred for PCI in Beijing Anzhen Hospital from January 2008 to December 2016. The patients were divided into continued warfarin therapy (195) or bridging anticoagulation therapy (311) groups.

A Review on the Effect of Traditional Chinese Medicine Against Anthracycline-Induced Cardiac Toxicity.

Anthracyclines are effective agents generally used to treat solid-tumor and hematologic malignancies. The use of anthracyclines for over 40 years has improved cancer survival statistics. Nevertheless, the clinical utility of anthracyclines is limited by its dose-dependent cardiotoxicity that adversely affects 10-30% of patients.

Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis.

The persistence of cholesterol-engorged macrophages (foam cells) in the artery wall fuels the development of atherosclerosis. However, the mechanism that regulates the formation of macrophage foam cells and impedes their emigration out of inflamed plaques is still elusive. Here, we report that adhesion receptor CD146 controls the formation of macrophage foam cells and their retention within the plaque during atherosclerosis exacerbation.

Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia.

Craniofacial microsomia (CFM) is a rare congenital anomaly that involves immature derivatives from the first and second pharyngeal arches. The genetic pathogenesis of CFM is still unclear. Here we interrogate 0.

Identification of a Mutation in FGF23 Involved in Mandibular Prognathism.

Mandibular prognathism (MP) is a severe maxillofacial disorder with undetermined genetic background. We collected a Chinese pedigree with MP which involved in 23 living members of 4 generations. Genome-wide linkage analysis were carried out to obtain the information in this family and a new MP-susceptibility locus, 12pter-p12.

Ambra1 modulates starvation-induced autophagy through AMPK signaling pathway in cardiomyocytes.

Recent research has revealed a role for Ambra1, an autophagy-related gene-related (ATG) protein, in the autophagic pro-survival response, and Ambra1 has been shown to regulate Beclin1 and Beclin1-dependent autophagy in embryonic stem cells and cancer cells. However, whether Ambra1 plays an important role in the autophagy pathway in cardiomyocytes is unknown. In this study, we hypothesized that Ambra1 is an important regulator of autophagy and apoptosis in cardiomyocytes.

Genome-wide linkage study suggests a susceptibility locus for isolated bilateral microtia on 4p15.32-4p16.2.

Microtia is a congenital deformity where the external ear is underdeveloped. Genetic investigations have identified many susceptibility genes of microtia-related syndromes. However, no causal genes were reported for isolated microtia, the main form of microtia.

WITHDRAWN: Ambra1 modulates starvation-induced autophagy through AMPK signaling pathway in cardiomyocytes.

This article has been withdrawn at the request of the author(s). The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.

Analysis of risk factors for recurrence after video-assisted pulmonary vein isolation of lone atrial fibrillation--results of 5 years of follow-up.

Objective: The purpose of the present study was to assess the efficacy of the long-term results after video-assisted pulmonary vein isolation and left atrial appendage excision for lone atrial fibrillation (AF) and to determine the most significant risk factors for the long-term results.

Methods: From December 2006 to December 2012, 332 consecutive patients with lone AF underwent minimally invasive surgical ablation at our center. Of the 332 patients, 91, who had undergone video-assisted pulmonary vein isolation>5 years earlier, were evaluated in the present study (48 with paroxysmal AF, 21 with persistent AF, and 22 with long-standing persistent AF).

A successful team treatment for left main shock syndrome.

Acute myocardial infarction complicated by cardiogenic shock and left main coronary artery disease is called left main shock syndrome. It is reported that the morbility and mortality of the syndrome is approximately 0.46% and 55%-80%, respectively.

Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci on chromosomes 3q25-26 and 21q22.

Background: Familial hypercholesterolemia (FH) is a heritable disorder that can increase the risk of premature coronary heart disease. Studies suggest there are substantial genetic heterogeneities for different populations. Here we tried to identify novel susceptibility loci for FH in a Chinese pedigree.

Pentacuspid aortic valve with severe aortic regurgitation.

Pentacuspid aortic valve is an extremely rare congenital aortic valve anomaly. In this case, pentacuspid aortic valve with severe aortic regurgitation was detected by transthoracic echocardiography and multiple-detector computed tomography; the patient recovered smoothly after aortic valve replacement.

[Effect of periodontal mechanical treatment on periodontal pathogenic bacteria in gingival crevicular fluid of chronic periodontitis patients].

Objective: To evaluate the subgingival prevalent rates of 6 periodontal pathogenic bacteria in gingival crevicular fluids of CP patients before and after treatment, to analyze the relationship between the prevalent variance and periodontal clinical parameters, and to provide a microbiologic method of evaluating curative effect and estimating the prognosis.

Methods: Gingival crevicular fluids of 13 CP patients were collected at baseline, 2 weeks, 2 months and 4 months after periodontal mechanical treatment. Also, gingival crevicular fluids were collected from 11 healthy subjects.

[Evaluation of MODS score system and its modified system for the postoperative patients with cardiac surgery].

Objective: To establish a feasible postoperative score system for cardiac surgery patients.

Methods: A prospective study was assigned of the 1 935 consecutive patients entering a single cardiac postoperative intensive care unit of Anzhen Hospital between Octorber, 2007 and January, 2008. Mutiple organ dysfunction score (MODS score) and modified mutiple organ dysfunction score (modified MODS score) were calculated daily at least three days, or until intensive care discharge or death.

Prospective versus retrospective ECG gating for dual source CT of the coronary stent: comparison of image quality, accuracy, and radiation dose.

Objective: To compare image quality, diagnostic accuracy and radiation dose of prospective and retrospective electrocardiogram (ECG) gated dual source computed tomography (DSCT) for the evaluation of the coronary stent, using conventional coronary angiography (CA) as a standard reference.

Design, Setting And Patients: Sixty patients (heart rates ≤ 70 bpm) with previous stent implantation who were scheduled for CA were divided in two groups, receiving either prospective or retrospective ECG gated DSCT separately. Two reviewers scored coronary stent image quality and evaluated stent lumen.

[Serum triglyceride is an independent risk factor for acute coronary heart disease events in 35 - 64 years old Chinese-Chinese Multi-provincial Cohort Study.].

Objective: To evaluate the association between serum triglyceride (TG) and the cardiovascular diseases (CVD) risk in Chinese population.

Methods: A total of 30, 378 men and women aged 35 - 64 years old were recruited in the Chinese-Chinese Multi-provincial Cohort Study (CMCS). The serum TG and other CVD risk factors were measured.

[The differences of hard tissue changes and stability of Angle's Class II division 1 extraction cases treated by Begg appliance and Edgewise appliance].

Objective: The purpose of this investigation is to compare the differences of hard tissue changes and stability in patients with Class II division 1 treated with extraction of four first premolars by Begg appliance and Edgewise appliance.

Methods: The study was conducted using lateral cephalometric radiographs taken pretreatment, posttreatment and following-up. Thirty patients who had an Angle's Class II division 1 malocclusion were treated with first premolar extractions (19 by Begg appliance and 11 by Edgewise appliance).

[Efficacy of integrated three-dimensional electroanatomic mapping with preacquired magnetic resonance images guide catheter atrial fibrillation ablation].

Objective: To investigate the efficacy of integrated electroanatomic mapping with preacquired magnetic resonance (MR) images guided catheter atrial fibrillation (AF) ablation.

Methods: From September 2005 to September 2006, 100 consecutive drug-refractory AF patients underwent catheter ablation (circumferential pulmonary vein (PV) linear ablation and electrical isolation) guided by a three-dimensional (3D) electroanatomic mapping system. Patients were randomly divided into two groups (n = 50 each group).

[Clinical features of late stent thrombosis after successful sirolimus-eluting stent implantation].

Objective: To analyze the potential risk factors for patients developing late stent thrombosis (LST) after successful sirolimus-eluting stents (SES) implantation.

Methods: The clinical, angiographic, procedural as well as antiplatelet therapy data were retrospectively analyzed in 8 patients with LST after successful SES implantation.

Results: The patient's mean age was (51 +/- 10) years old and indication for SESs was mostly acute coronary syndrome with multiple risk factors of cardiovascular diseases.

[A prospective study on relationship between blood uric acid levels, insulin sensitivity and insulin resistance].

Objective: To assess the effect of the serum uric acid (UA) on insulin resistance (IR).

Methods: In 1999, an investigation on risk factors of cardiovascular disease was carried out using stratified-random sampling method in 1056 participants. In 2004 another investigation was carried out in the same population.

[Cardiopulmonary responses to exercise in patients with hypertrophic obstructive cardiomyopathy].

Objective: The aim of this study was to observe the cardiopulmonary responses to exercise in patients with hypertrophic obstructive cardiomyopathy (HOCM) and to evaluate the effectiveness of percutaneous transluminal septal myocardial ablation (PTSMA).

Methods: Eighty-five patients with HOCM received cardiopulmonary exercise test using a cycle ergometer. Twenty sedentary volunteers served as controls.

A simple and feasible technique for repair of anomalous origin of the left pulmonary artery from the ascending aorta.

Anomalous origin of the left pulmonary artery from the ascending aorta is a rare congenital cardiac malformation and the direct reimplantation technique has been the strategy of choice, although postoperative restenosis across the anastomosis site is frequently observed. In the described case, a simple and feasible technique was used with satisfactory results at 20-month follow-up.