1,272 results match your criteria: "Antalya Training and Research Hospital.[Affiliation]"

Purpose: To determine whether there are quantitative changes in macular, choriocapillary, and peripapillary microvascular structures using optical coherence tomography angiography (OCTA) due to the presence of lupus nephritis (LN) in patients with systemic lupus erythematosus (SLE) and to investigate the correlation between these quantitative values and disease duration.

Methods: Fifty -five patients followed up in the rheumatology clinic with an SLE diagnosis were evaluated. As the control group, 61 eyes of 61 age- and gender-matched healthy individuals were included.

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  • * A study conducted whole-exome sequencing (WES) on 303 IEI patients in Türkiye, achieving likely genetic diagnoses for 41.1% and discovering 52 novel variants, as well as new potential IEI genes in six patients.
  • * The findings emphasize the importance of cross-cohort outcomes in IEI research and aim to enhance collaboration between clinical and scientific communities.
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Purpose: To compare the results of intravitreal bevacizumab (IVB) monotherapy and combined intravitreal bevacizumab and laser photocoagulation (LPC) therapies applied in the same session to patients with aggressive retinopathy of prematurity (A-ROP) in our clinic.

Methods: The study included 67 eyes of 37 patients diagnosed with A-ROP and treated. Forty-nine eyes treated with anti-vascular endothelial growth factor agent injection monotherapy for A-ROP treatment were included in the first group.

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Objectives: This study aimed to examine the frequency of anxiety disorder, coronavirus anxiety and health anxiety in tinnitus patients during the pandemic and also, determined the psychophysiological impact of COVID-19 on tinnitus.

Methods: This cross-sectional study was conducted in a tertiary central pandemic hospital from 15 July 2021 to 15 December 2022. In total, 124 patients with tinnitus and 77 healthy controls participated in the study.

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The Effect of Etrasimod on Fecal Calprotectin and High-sensitivity C-reactive Protein: Results From the ELEVATE UC Clinical Program.

Inflamm Bowel Dis

June 2024

Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

Article Synopsis
  • Biomarkers like fecal calprotectin (fCAL) and high-sensitivity C-reactive protein (hsCRP) may be useful in tracking ulcerative colitis (UC) progression and treatment response, potentially replacing endoscopies.
  • In the ELEVATE UC clinical trials, patients receiving the drug etrasimod showed significant differences in fCAL and hsCRP levels compared to those on placebo, correlating with better clinical outcomes.
  • The results indicated that lower levels of fCAL and hsCRP after treatment with etrasimod are predictive of effective long-term responses in patients with moderately to severely active UC.
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Objective: To determine whether patients with atypical squamous cells, cannot exclude high grade squamous intraepithelial neoplasia (ASC-H) cytology have a correlation between high-risk human papillomavirus (HPV) type and CIN 2+ lesion in final pathology.

Material And Methods: The study was conducted retrospectively, using data from three tertiary gynecologic oncology centers located in various regions of Turkey. Data from 5,271 patients who had colposcopy between January 2003 and January 2021 were analyzed.

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  • - The study focused on distinguishing tuberculous lymphadenitis (TBLN) from non-tuberculous lymphadenitis (NTBLN) in adults in Turkiye, analyzing demographic, clinical, and laboratory data from patients with swollen lymph nodes.
  • - A total of 812 patients were studied, revealing that TBLN was the most common diagnosis (53.69%), with higher occurrence in females and those who had elevated erythrocyte sedimentation rate and positive test results for tuberculosis (p < 0.05).
  • - The findings suggest that identifying specific variables can help clinicians improve their diagnosis and treatment strategies for adult lymphadenopathy.
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Objective: It was aimed to investigate the role of tonsil ultrasonography(USG) in the diagnosis of pediatric OSAS.

Methods: Before tonsillectomy (±adenoidectomy) for OSAS, all patients tonsil USG and polysomnography (PSG) tests were performed. Tonsil volume was measured preoperatively with the Brodsky tonsil grading scale and by postoperative water displacement test.

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Objectives: This study aimed to evaluate serum biomarker values measured during second-trimester aneuploidy screening in terms of their predictive ability for the development of retinopathy of prematurity (ROP) in premature infants.

Methods: This retrospective cohort study evaluated the data of 1985 idiopathic premature infants who underwent ROP screening from 2016 to 2022. The infants were divided into two groups according to the presence of ROP, and those with ROP were further evaluated in two subgroups based on the presence of proliferation.

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  • The study aimed to compare the effectiveness of myoinositol combined with folic acid against metformin, and their combination in treating insulin-resistant polycystic ovary syndrome (PCOS) in women.
  • Researchers analyzed data from 68 PCOS patients over three months, measuring various hormone levels and conducting oral glucose tolerance tests before and after treatment.
  • Results showed significant improvements in menstrual regularity and hormone levels for all groups, but no additional benefits were found when combining myoinositol and metformin compared to using them individually.
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  • A study evaluates patients with antibodies against myelin oligodendrocyte glycoprotein (anti-MOG-IgG), assessing their clinical, radiological, and demographic characteristics in relation to conditions like optic neuritis and myelitis.
  • Among the 104 participants, the majority were women, and the most common diagnoses included NMOSD, isolated optic neuritis, and ADEM, with a notable percentage showing symptoms resembling MS.
  • Findings indicate that older patients (>40 years) experienced more severe disability and poorer responses to treatment, highlighting the significance of anti-MOG-IgG in diagnosing NMOSD in patients without anti-NMO antibodies.
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Background: In this study, we aimed to analyze the temporal distribution of polymicrobial periprosthetic joint infections (PJIs), while also evaluating the patient risk factors associated with these infections following total joint arthroplasty at our institution across 2 distinct periods.

Method: This retrospective cross-sectional study evaluated 259 patients who had knee or hip PJI from 2001 to 2006 and 2018 to 2022. A PJI was diagnosed using the 2018 International Consensus Meeting criteria.

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Introduction: This prospective cohort study examines the relationship between post-sleeve gastrectomy (SG) weight loss and serum citrulline, I-FABP levels, and the I-FABP/citrulline ratio in obese patients, alongside the correlation with type 2 diabetes mellitus (T2DM) remission.

Methods: 88 participants were enrolled, including 48 undergoing SG and 21 with T2DM. 40 healthy individuals served as controls.

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Background/aim: This study investigated the possible degeneration in cochlear morphology induced by preeclampsia (PE) and the therapeutic/preventive effect of vitamin D (Vit D) and magnesium sulfate (MgSO) used separately and together on feto-maternal outcomes.

Materials And Methods: We created PE in rats using a reduced uterine perfusion pressure (RUPP) animal model and recorded blood pressure (BP), embryonic survival (ES), and embryonic weight (EW) and evaluated cochlear morphology by electron microscopy.

Results: The PE group had elevated BP, a decreased number and weight of live pups, and significant degeneration in the cochlea compared to the sham group.

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Background: It is important to accurately determine the blood ethanol concentration (BEC) to ensure appropriate diagnosis and treatment of patients in the emergency department (ED) and protect their legal rights. This study aimed to determine whether sterilization of venipuncture site with ethanol, which is frequently used in practice in the ED would affect BEC.

Methods: Venous blood samples were collected by two consecutive techniques from 94 individuals who were admitted to the ED, had an indication for BEC measurement, and volunteered to participate in the study.

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Background/aim: In this study, it was aimed to retrospectively compare the effect of greater occipital nerve (GON) block performed with ultrasonography using low (0.3%) and high (0.5%) concentrations of bupivacaine on pain scores and patient satisfaction in chronic migraine (CM).

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Background: Migraine is a disease characterized by headache attacks. The disease is multifactorial in etiology and genetic and environmental factors play role in pathogenesis. Migraine can also be accompanied by psychiatric disorders like neurotism and obsessive compulsive disorder.

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  • The study aimed to compare the sputum microbiota of community-acquired pneumonia patients with COPD and asthma in Turkey, considering differences in their clinical presentation and microbiological findings.
  • It included 246 hospitalized patients, revealing that a significant portion had COPD (52.9%) or asthma (14.2%), with Pseudomonas aeruginosa being the most commonly identified pathogen.
  • Results indicated that CAP patients with COPD had more severe disease presentations and specific treatment needs compared to those with asthma, highlighting the importance of tailored management for pneumonia patients.
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Pseudoaneurysm (PA) and carotid cavernous fistula (CCF) of the internal carotid artery (ICA) is an uncommon complication of endoscopic endonasal surgery that occurs in 1% of cases. We report on the successful placement of flow-diverting stents (FDS) to ICA pseudoaneurysm and caroticocavernous fistula caused by iatrogenic ICA injury for a pituitary adenoma in a 37-year-old female. After placement of the pipeline shield given a certain time, dual antiplatelet agents (DAPT) and follow-up angiogram verified complete aneurysm obliteration and effective endoluminal reconstruction of the injured vessel.

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Introduction: Several prognostic factors have been identified in patients with metastatic bladder cancer (BC). As it is known, older adult patients are prone to nutritional deficiency. The knowledge about nutrition and impact on survival in older patients with metastatic bladder cancer is missing.

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Objective: Primary immune thrombocytopenia (ITP) is an acquired disorder of platelets with a complex and unclear mechanism of increased immune destruction or impaired production of platelets. While the management of ITP is evolving, there is still a need for guidance, particularly in certain circumstances such as pregnancy, emergencies, or patients requiring co-medications. We aimed to determine the tendencies of hematologists in Türkiye in the event of such special considerations.

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Objectives: Head and neck cancers (HNCs) represent a significant global health concern due to high morbidity and mortality rates. Despite therapeutic advances, the prognosis for advanced or recurrent cases remains challenging. Nivolumab obtained approval for recurrent or metastatic HNC based on the Phase III CheckMate 141 trial.

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  • The study focused on understanding how common fibromyalgia syndrome (FS) and widespread pain are among patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS), while also examining related clinical and demographic factors.
  • Conducted over 14 centers in Türkiye, the research included 661 patients, differentiating those with FS from those with widespread pain but not meeting FS criteria.
  • Results showed that significant percentages of both RA (34.1% with FS) and AS (29.2% with FS) patients had high polysymptomatic distress (PSD) scores, indicating a high level of discomfort and symptomatology associated with their conditions.
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