Tricuspid Annuloplasty Using a Handmade Gore-Tex Band: A Retrospective Study, Case Series, and Literature Review.

Background Tricuspid valve regurgitation is frequently overlooked by cardiologists and cardiac surgeons alike; consequently, the tricuspid valve is often referred to as "the forgotten" valve. It is the most common complication of left heart valve disease. Ring annuloplasty and suture (De Vega) annuloplasty represent two common surgical treatment techniques.

Secondary congenital nephrotic syndrome complicated by acute mesenteric ischemia: A case report.

Thromboembolic events are among the most serious, yet rare complications of nephrotic syndrome. While peripheral venous thrombosis and pulmonary embolism are the most common, superior mesenteric artery thrombosis is a rare but life-threatening occurrence. We present a case of severe cytomegalovirus (CMV) infection complicated by congenital nephrotic syndrome, leading to mesenteric ischemia.

Neuroichthyosis With a De Novo Variant c.494C>T in ELOVL1 and Severe Pruritus Relieved by Dupilumab.

We report a patient with neuroichthyosis with an ELOVL1 variant associated with severe pruritus who responded well to dupilumab therapy. Our case is the third known patient reported with this de novo heterozygous dominant variant. The feature of severe progressive pruritus greatly impairing quality of life is unique among these reports.

Comparison of short TE CT-like MRI sequences and UHR-CT in cadaveric wrist study.

Rationale And Objectives: To evaluate the performance of CT-like MRI sequences (gradient echo with radial k-space filling (GRE), pointwise encoding time reduction with radial acquisition (PETRA), radial Ultrashort Echo Time (UTE)) versus ultra-high-resolution CT (UHR-CT) in assessing carpal bones and soft tissue calcifications in cadaveric wrists.

Materials And Methods: Five anonymized cadaveric forearm specimens were imaged using a 3 T MRI system with GRE, PETRA, and radial UTE sequences, alongside UHR-CT. Evaluated parameters included bone contours, carpal bone dimensions, cortical thickness, lesion size and soft tissue calcifications.

Real-World Treatment Patterns and Outcomes in Patients With Bacillus Calmette-Guérin-Unresponsive High-Risk Non-Muscle-Invasive Bladder Cancer: A Multicountry Medical Chart Review.

Introduction: Treatment patterns for patients with bacillus Calmette-Guérin (BCG)-unresponsive high-risk non-muscle-invasive bladder cancer (NMIBC) who are ineligible for or decline radical cystectomy (RC) are inconsistently reported. We retrospectively described demographic, clinical, and treatment characteristics for these patients and assessed their clinical outcomes.

Patients And Methods: Medical charts of patients with BCG-unresponsive high-risk NMIBC (carcinoma in situ [cohort A] or T1/high-grade Ta [cohort B]) who were ineligible for or declined RC documented between January 1, 2011, and December 31, 2018, at 15 academic centers were reviewed.

Bedtime vs. morning aspirin intake on the diurnal variability of blood pressure and platelet aggregation for the prevention of coronary artery diseases: a systematic review and meta-analysis.

Purpose: Low-dose aspirin had been widely used for secondary prevention of cardiovascular disease. Chronopharmacology of arterial hypertension and platelet aggregation impacts the long-term thromboembolic risk in patients with cardiovascular disease. Therefore, clinical studies have proposed optimising aspirin dosing time.

Reducing invasiveness in liver surgery-where is the limit?

In this article, we comment on the article by Wang published in the recent issue of the . Most prominent advancements in liver surgery in the last two decades are related to refinements in surgical technique (extraglissonean approach) and advancements in surgical technology (laparoscopy and robotics). In this article, authors present both these aspects: Laparoscopic segmentectomy using extraglissonean approach.

Twists and turns: unraveling the mystery of ileosigmoidal knotting, a rare and intriguing acute intestinal obstruction (a report of 3 cases).

Among the rare and complex causes of acute intestinal occlusion: volvulus due to the ileosigmoid node. The latter is secondary to the terminal ileum which will wrap around the base of the sigmoid colon and its meso, resulting in the formation of a node. Its natural evolution is the ischemia of the ileum and sigmoid, necessitating prompt emergency surgical intervention as the primary treatment approach.

Spontaneous left pneumothorax revealing an atypical carcinoid tumor: a case report.

The association between spontaneous pneumothorax and a bronchial tumor is rare, and even more so with an atypical carcinoid tumor. This rare and unexpected case highlights the importance of raising clinician awareness about investigating the underlying cause of pneumothorax through endoscopic exploration. A 52-year-old female was exposed to passive smoking by her husband for 20 years.

Effectiveness of the XBB.1.5 COVID-19 Vaccines Against SARS-CoV-2 Hospitalisation Among Adults Aged ≥ 65 Years During the BA.2.86/JN.1 Predominant Period, VEBIS Hospital Study, Europe, November 2023 to May 2024.

We estimated the effectiveness of the adapted monovalent XBB.1.5 COVID-19 vaccines against PCR-confirmed SARS-CoV-2 hospitalisation during the BA.

Anatomical osteocartilaginous reconstruction of MacLaughlin lesion in chronic locked posterior shoulder dislocation: A novel technique.

Introduction: Chronic Posterior shoulder dislocation presents significant challenges, with treatment decisions influenced by the duration of the injury and the severity of humeral head damage. This report highlights an innovative technique for reconstructing humeral head defects using an osteocartilaginous graft from costal cartilage, offering insights into the surgical procedure and the patient's favorable recovery outcomes.

Presentation Of Case: The patient, a 23-year-old male with no significant medical history, was treated for a neglected posterior shoulder dislocation of two months' duration, complicated by a reverse Hill-Sachs lesion.

Correlation between non-motor symptoms and eye movements in Parkinson's disease patients.

Introduction: Parkinson's disease (PD) presents with a variety of non-motor symptoms such as sleep disorders, hyposmia, pain, cognitive dysfunction, neuropsychiatric and autonomic symptoms. One of the most neglected motor symptoms is the impairment of eye movements, which occurs in 75% of PD patients. The aim of our study was to investigate the relationship between the severity of non-motor symptoms and the impairment of different types of eye movements.

Genotypic diversity of the c region and its correlation with gastric disease outcomes.

infection is a major cause of peptic ulcer and gastric adenocarcinoma. The infection progression to severe diseases depends on several factors, including bacterial ones. CagA and VacA are two major virulence factors widely studied and implicated in diseases.

Thrombogenicity assessment of surface-modified flow diverters: the impact of different surface modification strategies on thrombin generation in an acute test.

Background: New generation flow-diverting stents have benefited from recent technological advances to reduce their thrombogenicity. This in vitro study is the first of its kind to compare multiple surface modified flow diverters with their bare metal counterparts.

Methods: A thrombin generation assay (TGA) was used to compare thrombin generation resulting from different stent types with glass beads (positive control) and plasma (negative control).

Spinal muscular atrophy type 3 and treatment adherence in a changing therapeutic landscape: a national-center experience.

Aim: To report on treatment outcomes in adult patients with spinal muscular atrophy type 3 (SMA3) who had their nusinersen treatment initiated in adulthood.

Methods: The study enrolled 11 adults treated with nusinersen for SMA3 at the Croatian National Referral Centre for Neuromuscular Disorders from 2019 to 2022. We prospectively collected validated SMA outcome measures: Revised Hammersmith score (RHS), Revised Upper Limb Module, and 6-minute walk test (6MWT) as motor function outcomes and the Individualized Neuromuscular Quality of Life questionnaire.

Effectiveness of biological therapy in severe asthma: a retrospective real-world study.

Unlabelled: Aim- To compare the effectiveness of different biologic medications for the treatment of severe asthma.

Methods: We retrospectively collected data on 74 patients treated with one of four different biologics (omalizumab, mepolizumab, reslizumab, or benralizumab) at the Jordanovac Clinic for Pulmonary Diseases, Zagreb, Croatia for at least two years. The patients were compared in terms of the number of exacerbations, dose of oral corticosteroids (OCS), asthma control test (ACT), forced expiratory volume in 1 second (FEV1), forced vital capacity, fraction of exhaled nitric oxide (FeNO), number of blood eosinophils, and total immunoglobulin E (IgE).

Clinical relevance of engineered cartilage maturation in a randomized multicenter trial for articular cartilage repair.

Cartilage lesions do not heal spontaneously and predispose to osteoarthritis. Functional cartilage tissues, engineered using autologous chondrocytes, have a therapeutic advantage over conventional cellular therapies in preclinical studies. Here, we tested whether ex vivo maturation of engineered grafts for cartilage repair leads to improved patient benefit.

Pulsed field ablation for atrial fibrillation.

Introduction: Atrial fibrillation is the most common sustained arrhythmia, associated with substantial morbidity and a reduced quality of life. The current standard of care, transcatheter pulmonary vein isolation using thermal ablation techniques, provides symptom relief but carries a risk of collateral tissue damage. In recent years, pulsed field ablation, a nonthermal technique based on irreversible electroporation, has emerged as a promising alternative to conventional thermal ablation methods.

Longitudinal Associations Between Self-reported Schizotypy Dimensions and White Matter Integrity Development During Adolescence.

Background: Alterations of white matter microstructure have been reported in the psychosis spectrum. However, the development of these alterations during preclinical stages remains poorly understood. The framework proposed by schizotypy research as the personality base for liability to develop psychosis spectrum disorders offers 3 interconnected dimensions thought to impact neurodevelopment, affording an opportunity to investigate premorbid risk.

Management of vaginal leiomyomas during pregnancy - A case report.

Introduction: Uterine fibroids (leiomyomas) are the most common benign tumors of the female genital tract, affecting about 20 % of women over 35 years of age. Although these tumors are common in the uterus, their occurrence in the vagina is extremely rare. Vaginal fibroids may present as a vaginal mass, often diagnosed at an advanced stage, as they can be mistaken for other benign conditions.

Development of a diagnostic checklist to identify functional cognitive disorder versus other neurocognitive disorders.

Background: Functional cognitive disorder (FCD) poses a diagnostic challenge due to its resemblance to other neurocognitive disorders and limited biomarker accuracy. We aimed to develop a new diagnostic checklist to identify FCD versus other neurocognitive disorders.

Methods: The clinical checklist was developed through mixed methods: (1) a literature review, (2) a three-round Delphi study with 45 clinicians from 12 countries and (3) a pilot discriminative accuracy study in consecutive patients attending seven memory services across the UK.

The moderating effect of the psychosocial working conditions (effort/reward/overcommitment) on the association between noise annoyance and cognitive performance among adolescents.

Objectives: The primary objective of the current study was to evaluate the correlation between noise-induced annoyance and the cognitive performance within the Lebanese adolescent population and the moderating effect of psychosocial work aspects-namely effort, reward, and overcommitment- in this association.

Methods: An anonymous online survey was conducted in Lebanon between April and May 2023, using a snowball sampling technique and distributed across various social media platforms, to gather data from Lebanese adolescents. The sample was composed of 1269 adolescents.