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Overexpression of lncRNA NLIPMT Inhibits Colorectal Cancer Cell Migration and Invasion by Downregulating TGF-β1.
Cancer Manag Res
July 2020
The First Affiliated Hospital of Henan University of TCM, Anorectal Disease Clinic, Zhengzhou City, Henan Province 450000, People's Republic of China.
Background: NLIPMT, as a tumor suppressive lncRNA, has only been investigated in breast cancer, while its roles in other types of cancer remain unknown. This study aimed to explore the role of NLIPMT in colorectal cancer (CRC).
Methods: Expression levels of NLIPMT and TGF-β1 in two types of CRC tissue (Non-tumor tissues and tumor tissues) were measured and compared by qRT-PCR and paired -test, respectively.