746 results match your criteria: "Annual Review Of Cell And Developmental Biology[Journal]"
Annu Rev Cell Dev Biol
October 2023
Tananbaum Center for Theoretical and Analytical Human Biology, Yale University School of Medicine, New Haven, Connecticut, USA; email:
Annu Rev Cell Dev Biol
October 2023
Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA; email:
Annu Rev Cell Dev Biol
October 2023
Department of Biology, University of Nevada, Reno, Nevada, USA; email:
Our understanding of cell and developmental biology has been greatly aided by a focus on a small number of model organisms. However, we are now in an era where techniques to investigate gene function can be applied across phyla, allowing scientists to explore the diversity and flexibility of developmental mechanisms and gain a deeper understanding of life. Researchers comparing the eyeless cave-adapted Mexican tetra, , with its river-dwelling counterpart are revealing how the development of the eyes, pigment, brain, cranium, blood, and digestive system evolves as animals adapt to new environments.
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October 2023
Instituto Gulbenkian de Ciência, Oeiras, Portugal; email:
The neural retina, at the back of the eye, is a fascinating system to use to discover how cells form tissues in the context of the developing nervous system. The retina is the tissue responsible for perception and transmission of visual information from the environment. It consists of five types of neurons and one type of glia cells that are arranged in a highly organized, layered structure to assure visual information flow.
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October 2023
The Francis Crick Institute, London, United Kingdom; email:
Annu Rev Cell Dev Biol
October 2023
Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom; email:
Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and tissue development. The molecular mechanisms determining how and where filopodia grow and retract need to integrate mechanical forces and membrane curvature with extracellular signaling and the broader state of the cytoskeleton. The involved actin regulatory machinery nucleates, elongates, and bundles actin filaments separately from the underlying actin cortex.
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October 2023
Department of Neuroscience, Yale University School of Medicine, New Haven, Connecticut, USA; email:
The life of eukaryotic cells requires the transport of lipids between membranes, which are separated by the aqueous environment of the cytosol. Vesicle-mediated traffic along the secretory and endocytic pathways and lipid transfer proteins (LTPs) cooperate in this transport. Until recently, known LTPs were shown to carry one or a few lipids at a time and were thought to mediate transport by shuttle-like mechanisms.
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October 2023
Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, California, USA; email:
Annu Rev Cell Dev Biol
October 2023
Lewis-Sigler Institute for Integrative Genomics and Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA; email:
Myriad mechanisms have evolved to adapt to changing environments. Environmental stimuli alter organisms' physiology to create memories of previous environments. Whether these environmental memories can cross the generational barrier has interested scientists for centuries.
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October 2023
Donders Institute for Brain, Cognition, and Behavior, Radboud University, Nijmegen, The Netherlands; email:
Annu Rev Cell Dev Biol
October 2023
Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California, USA; email:
Annu Rev Cell Dev Biol
October 2023
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA; email:
Multicellular organisms generate tissues of diverse shapes and functions from cells and extracellular matrices. Their adhesion molecules mediate cell-cell and cell-matrix interactions, which not only play crucial roles in maintaining tissue integrity but also serve as key regulators of tissue morphogenesis. Cells constantly probe their environment to make decisions: They integrate chemical and mechanical information from the environment via diffusible ligand- or adhesion-based signaling to decide whether to release specific signaling molecules or enzymes, to divide or differentiate, to move away or stay, or even whether to live or die.
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October 2022
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA; email:
Annu Rev Cell Dev Biol
October 2022
Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, USA; email:
Annu Rev Cell Dev Biol
October 2022
Department of Molecular and Cellular Biology, University of California, Davis, California, USA; email:
Ciliates are a diverse group of unicellular eukaryotes that vary widely in size, shape, body plan, and ecological niche. Here, we review recent research advances achieved with ciliate models. Studies on patterning and regeneration have been revived in the giant ciliate , facilitated by modern omics methods.
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October 2022
Department of Molecular and Cellular Physiology and Institute of Stem Cell Biology and Regenerative Medicine, School of Medicine, Stanford University, Stanford, California, USA; email:
Annu Rev Cell Dev Biol
October 2022
Department of Cell Biology, New York University School of Medicine, New York, NY, USA; email:
Annu Rev Cell Dev Biol
October 2022
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; email:
Successful immune responses depend on the spatiotemporal coordination of immune cell migration, interactions, and effector functions in lymphoid and parenchymal tissues. Real-time intravital microscopy has revolutionized our understanding of the dynamic behavior of many immune cell types in the living tissues of several species. Observing immune cells in their native environment has revealed many unanticipated facets of their biology, which were not expected from experiments outside a living organism.
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October 2022
Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, United Kingdom; email:
Annu Rev Cell Dev Biol
October 2022
Department of Molecular and Cell Biology, University of California, Berkeley, California, USA; email:
Annu Rev Cell Dev Biol
October 2022
Department of Cell Biology, Duke University, Durham, North Carolina, USA; email:
During organismal development, organs and systems are built following a genetic blueprint that produces structures capable of performing specific physiological functions. Interestingly, we have learned that the physiological activities of developing tissues also contribute to their own morphogenesis. Specifically, physiological activities such as fluid secretion and cell contractility generate hydrostatic pressure that can act as a morphogenetic force.
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October 2022
Human Technopole, Milan, Italy; email:
Cilia are ubiquitous microtubule-based eukaryotic organelles that project from the cell to generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal dynein motors and other complexes to achieve beating. Primary cilia are immotile and act as signaling hubs, with receptors shuttling between the cytoplasm and ciliary compartment.
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October 2022
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany; email:
Organoids are miniaturized and simplified versions of an organ produced in vitro from stem or progenitor cells. They are used as a model system consisting of multiple cell types forming an architecture relevant to the organ and carrying out the function of the organ. They are a useful tool to study development, homeostasis, regeneration, and disease.
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October 2022
Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA; email: