33,834 results match your criteria: "Annals of surgery[Journal]"

Target Artery Outcomes Following Endovascular versus Open Surgical Repair of Thoracoabdominal Aortic Aneurysms - A Single Center Comparative Study.

Ann Surg

November 2024

Department of Cardiothoracic and Vascular Surgery, Advanced Aortic Research Program at the University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX.

Objective: To compare target artery (TA) outcomes after fenestrated or branched endovascular aortic repair (FB-EVAR) versus open surgical repair (OSR) of thoracoabdominal aortic aneurysms (TAAAs).

Background: Few studies have compared TA outcomes after endovascular incorporation and open reconstruction.

Methods: Among consecutive patients who underwent elective OSR or FB-EVAR of TAAAs (2008-2020), we reviewed those who had postoperative imaging studies evaluating TA.

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Objective: To assess the incidence of posthepatectomy liver failure (PHLF) and the role of the future liver remnant (FLR) in children undergoing major hepatectomy.

Summary Background Data: Incidence and risk factors of PHLF in children are unclear, with no validated definition for this age group. Consequently, the role of the FLR in pediatric hepatectomy and evidence-based preoperative guidelines remain undefined.

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Objective: The aim of this study was to evaluate the different phases of the learning curve for robotic distal pancreatectomy (RDP) in international expert centers.

Summary Background Data: RDP is an emerging minimally invasive approach; however, only limited, mostly single center data are available on its safe implementation, including the learning curve.

Methods: Consecutive patients undergoing elective RDP from 16 expert centers across three continents were included to assess the learning curve.

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Metabolic surgery - operating on a normal organ for a beneficial metabolic gain - is not only an emerging discipline of surgery but the progenitor of therapy for the major global afflictions of atherosclerotic cardiovascular disease, cancer, type 2 diabetes, and obesity, as well as at least 18 other disease entities.

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Background: Postoperative morbidity can reduce quality of life, physical performance, and tolerability of postoperative chemotherapy in patients with colorectal liver metastases (CRLM). Exercise can improve these outcomes in some cancer populations. However, it remains unknown whether exercise can be delivered in the early postoperative period following surgery for CRLM without increasing the risk of harms.

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Importance: The current research aimed to conduct a detailed analysis of intraoperative surgical performance, short-term outcomes, identify and categorize technical errors, and hazard-zones enacted during total gastrectomy performed robotically and laparoscopically by surgeons. Prospective research is needed to determine whether the technical advantages of robotic surgery translate to patient outcomes.

Objective: Identify and process risk areas in robot-assisted total gastrectomy (RTG) and laparoscopic total gastrectomy (LTG) to get the best patient results.

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Objective: To determine the association between residence in racialized neighborhoods with direct healthcare expenditure and days at home (DAH) after moderate to severe traumatic brain injury (TBI).

Summary Background Data: Differences in ethno-racial background have been associated with health outcome disparities. Much of this prior research was conducted in settings without universal healthcare coverage.

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Objective: To investigate patency and clinical outcomes of alloplastic and other venous interposition graft materials in pancreatic surgery.

Background: Vascular pancreatic surgery is increasingly performed for locally advanced pancreatic neoplasms. Different than other centers, we prefer to use alloplastic vascular graft materials for superior mesenteric vein and portal vein interposition in pancreatic surgery.

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Article Synopsis
  • The study aims to assess how socioeconomic deprivation affects postoperative outcomes in patients who have undergone surgery for sigmoid diverticulitis (SD).
  • Conducted across 41 French hospitals from 2010 to 2021, researchers found that 20% of the 6,415 patients experienced severe complications within 90 days post-surgery.
  • Results indicated that higher levels of socioeconomic deprivation are linked to an increased risk of severe complications, even after adjusting for factors like age, sex, and surgery type.
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Objective: To examine perceived OR ergonomics facilitators and barriers, with a focus on the interdisciplinary team.

Summary Background Data: Poor ergonomics causes musculoskeletal injuries affecting all operating room (OR) staff with repercussions on patient care, outcomes, and sustainability. Lack of ergonomic awareness and education are risk factors.

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Objective: To quantify recent trends in access to timely, high-quality, affordable surgical care in the US.

Background: Insufficient access to surgical care remains an ongoing concern in the US. Previous attempts to understand and quantify barriers in access to surgical care in the US lack a comprehensive, policy-relevant lens.

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Objective: To evaluate machine learning models' performance in predicting acute pancreatitis severity using early-stage variables while excluding laboratory and imaging tests.

Summary Background Data: Severe acute pancreatitis (SAP) affects approximately 20% of acute pancreatitis (AP) patients and is associated with high mortality rates. Accurate early prediction of SAP and in-hospital mortality is crucial for effective management.

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Objective: To review the surveillance of IPMN, the risk of pancreatic cancer and the cost of surveillance.

Background: The increasing IPMN prevalence and low pancreatic cancer associated with IPMN question the necessity and cost-effectiveness of surveillance. Guidelines favour a 'watch and wait' approach, lacking clarity on stopping surveillance.

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Objective: This study aimed to compare the ability of a deep-learning platform (the MACSSwin-T model) with healthcare professionals in detecting cerebral aneurysms from operative videos. Secondly, we aimed to compare the neurosurgical team's ability to detect cerebral aneurysms with and without AI-assistance.

Background: Modern microscopic surgery enables the capture of operative video data on an unforeseen scale.

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Population-Based Cohort Study on Treatment and Overall Survival of Patients Clinically Diagnosed With T1 Ampullary Cancer.

Ann Surg

October 2024

Department of Surgery and School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.

Article Synopsis
  • The study aimed to assess treatment outcomes, overall survival (OS), and factors influencing OS in patients with T1 ampullary cancer, a rare type of gastrointestinal cancer.
  • Out of 244 patients with clinical T1 ampullary cancer, 75% underwent surgery, but a significant number were found to have more advanced disease upon further examination.
  • The results indicated a stark difference in survival based on disease classification, with poor prognostic factors including higher pathological N classification and poorly differentiated tumors, emphasizing the need for aggressive treatment like pancreatoduodenectomy for T1 cases.
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Article Synopsis
  • The study aimed to assess the prognostic significance of circulating tumor DNA (ctDNA) in patients with localized pancreatic ductal adenocarcinoma (PDAC) undergoing neoadjuvant chemotherapy (NAC) using a specific testing method called digital droplet PCR (ddPCR).
  • Researchers enrolled 84 patients and found that mutant KRAS ctDNA was present in a significant percentage of patients at various treatment stages, with clearance of ctDNA during NAC linked to better overall survival (OS).
  • The presence of the KRAS G12V mutation after surgery was strongly associated with poorer survival outcomes, indicating its potential as a negative prognostic marker in this patient group.
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Article Synopsis
  • - The study examined issues in emergency inter-hospital transfers of severely injured patients, specifically at high-level trauma centers, finding that the re-triage process often takes longer than the recommended two-hour window, which increases mortality risk.
  • - Researchers conducted a thorough analysis involving 64 healthcare professionals to identify failures in the re-triage process, mapping out 178 issues, with the most critical being insufficient transport staff, problems with imaging transmission, and gaps in clinical information exchange.
  • - The study concludes that significant failures in the transfer process stem from inadequate transportation resources and incomplete clinical information sharing, highlighting the need for improvements in these areas to enhance patient outcomes.
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Article Synopsis
  • This study investigates how financial toxicity (FT)—the financial strain from medical treatment—affects emotional (EWB) and social well-being (SWB) in patients post-gastrointestinal (GI) surgery.
  • Conducted between January 2022 and January 2023, the research involved 188 patients, and key findings included that nearly a third experienced FT, with specific risk factors like being single or not receiving chemotherapy/radiation identified.
  • The results indicate a direct correlation between higher levels of FT and poorer emotional and social well-being, suggesting that pre-operative screening for FT could help in providing supportive interventions for affected patients.
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Objective: To understand mortality and secondary outcomes in patients with both end-stage kidney disease (ESKD) and chronic limb-threatening ischemia (CLTI) after no procedural treatment, primary amputation, endovascular treatment, and open surgery.

Summary Background Data: ESKD and CLTI commonly cooccur and limited prior work has demonstrated poor outcomes including one-year survival despite treatment.

Methods: We conducted a retrospective national cohort study of United States Renal Data System data from January 1, 2016 to December 31, 2019 to determine mortality, major postoperative complications, and other outcomes.

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Article Synopsis
  • This study investigated the impact of Flavin Mononucleotide (FMN) levels in the flush solution used during liver cold storage on transplant outcomes, involving 62 liver transplant recipients.
  • The results showed that higher FMN levels were linked to worse graft survival rates, with the low-FMN group having a 100% one-year survival compared to 77% for the high-FMN group.
  • The study concluded FMN level is a reliable biomarker for predicting post-transplant success, suggesting that strategies like machine perfusion could improve outcomes for livers with high FMN levels.
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