Brachial-Ankle Pulse Wave Velocity Reflects Regional Arterial Stiffness and Distensibility in Patients with Abdominal Aortic Aneurysm.

We investigated the association between brachial-ankle pulse wave velocity (PWV) and arterial stiffness and distensibility in the aneurysmal sac of abdominal aortic aneurysm (AAA). Data from 49 patients with AAA from June 2020 to November 2022 at Tokyo Medical University Hospital were retrospectively analyzed. Brachial-ankle PWV (cm/s) was obtained via an automated oscillometric method.

Quantifying Muscle Volume Deficits Among 38 Lower Extremity Muscles in Collegiate Football Athletes After Anterior Cruciate Ligament Reconstruction.

Background: Quadriceps dysfunction is ubiquitous after anterior cruciate ligament (ACL) reconstruction (ACLR). Addressing quadriceps dysfunction is crucial to improve function, reduce the reinjury risk, and maintain long-term knee health. While deficits specific to the quadriceps are well documented, less is known about the effect of an ACL injury on other lower extremity muscle groups.

Knee phenotypes distribution according to CPAK classification in Turkish population.

Objective: This study aimed to investigate the distribution of knee phenotypes based on the CPAK classification in healthy nonarthritic subjects and osteoarthritic patients in Türkiye.

Methods: Radiological EOS analysis of nonarthritic 1172 knees and osteoarthritic 571 knees was evaluated to clarify the distribution of CPAK classification. The knees were categorized into 9 subgroups according to the arithmetic hip-knee-ankle (aHKA) angle and joint-line obliquity (JLO).

Implementation of a clinical pathway for diabetes-related foot ulcers reduced the number of amputations and shortened hospital stay.

Introduction: Diabetes-related foot ulcer (DFU) is the leading cause for lower extremity amputations (LEAs) in western countries, and may cause social isolation, depression, and death. However, people with DFU are not offered the same prioritized care as cancer patients, despite comparable mortality rates. We therefore decided to create a clinical pathway for patients with DFU.

Radiological safety atlas of minimally invasive midfoot fusion: A cadaver study.

Purpose: The popularity of minimally invasive (MIS) foot surgery continues to grow. However, it comes with certain limitations that present notable challenges. One significant hurdle is the absence of direct visualization of neurovascular structures and tendons.

Preoperative Optimization of Patients Undergoing Orthopedic Foot and Ankle Surgery: A Single Institution Cohort.

Introduction: Careful preoperative patient preparation for orthopedic foot and ankle surgery can help manage postoperative expectations and avoid suboptimal outcomes. Our quality improvement initiative aimed to reduce emergency department (ED) visits within 30 days postsurgery by enhancing preoperative education.

Methods: We focused on four outcomes associated with receipt of written preoperative information: (1) related ED visits within 30 days of surgery, (2) average number of patient portal messages, (3) phone calls initiated by patients, and (4) staff team experience survey results.

The effect of sciatic nerve block on sciatic nerve depth and pain level in patients with ankle fracture based on different approaches under ultrasound guidance.

To investigate the clinical efficacy of using different approach sciatic nerve blocks on the sciatic nerve depth and pain degree in patients with ankle fracture. A retrospective analysis was conducted on 151 patients with ankle fractures who were admitted to the hospital from May 2020 to May 2023. The patients were divided into a control group (n=76) using the greater trochanteric plane approach (GTA) and an observation group (n=75) using the suprapopliteal approach (PA).

Musculoskeletal model predictions sensitivity to upper body mass scaling during gait.

Musculoskeletal modeling based on inverse dynamics provides a cost-effective non-invasive means for calculating intersegmental joint reaction forces and moments, solely relying on kinematic data, easily obtained from smart wearables. On the other hand, the accuracy and precision of such models strongly hinge upon the selected scaling methodology tailored to subject-specific data. This study investigates the impact of upper body mass distribution on internal and external kinetics computed using a comprehensive musculoskeletal model during level walking in both normal weight and obese individuals.

The impact of running experience and shoe longitudinal bending stiffness on lower extremity biomechanics: a cross-sectional study.

: The impact of shoe stiffness on running biomechanics is well-documented, while the specific effect on the performance of biomechanically distinct groups such as novice runners and experienced runners is still largely unexplored. The study aimed to evaluate the biomechanical effect of different shoe longitudinal bending stiffness on the lower limb during running in novice runners and experienced runners. : Twelve experienced runners and ten novice runners ran at a speed of 4.

Change of the anterior talus-fibular ligament length of asymptomatic patients during inversion stress test.

Objective: Aim: To study the ATFL length among asymptomatic population of young patients on both joints by using the method of ultrasound examination of the ankle joint and applying the inversion stress test.

Patients And Methods: Materials and Methods: the length of the ATFL was measured among 60 boys and 60 girls during the research. Sonography was performed on both joints, in each of the two studied positions, three times per position in order to obtain the average ligament length.

Arthroscopically Assisted Reduction and Fixation of Acute Tillaux, Pilon, Bosworth, Talar, and Calcaneal Fractures: A Systematic Review.

Increased use of arthroscopically assisted techniques for the treatment of ankle fractures has been reported. Despite their rapid development, there is only one systematic review regarding arthroscopically assisted treatment of ankle fractures, in which, however, only malleolar fracture studies are included. Various other types of ankle fractures have also been treated with arthroscopically assisted procedures.

Primary Antiphospholipid Syndrome Causing Critical Limb Ischemia and Ultimately Amputation in an Otherwise Healthy Young Female.

This case report describes an otherwise healthy 43-year-old female who presented with severe pain, foot drop, and critical limb ischemia to her left foot caused by thrombosis of a peripheral artery secondary to antiphospholipid syndrome. Antiphospholipid syndrome is an autoimmune disease that frequently manifests as recurrent arterial and/or venous thrombotic events, ischemic strokes, and miscarriages. Antiphospholipid syndrome affecting primarily the arteries is less common as compared to venous thrombosis.

Posterior cruciate ligament resection increases intraoperative lateral and medial flexion laxity during total knee arthroplasty.

Purpose: This study reports the relationship between posterior cruciate ligament (PCL) retention vs resection and soft tissue laxity and balance throughout flexion using a robotically controlled ligament tensioner.

Methods: 55 robotic-assisted TKAs (Total knee arthroplasty) were retrospectively reviewe. The robotic ligament tensioner collected laxity data both before and after PCL resection.

Biomechanics of the bobsleigh push phase.

The purpose of this work was to provide a fundamental, in-depth analysis of kinematics and kinetics of the bobsleigh push phase to establish a basis for performance analysis and enhancement. Fifteen elite male athletes performed maximal effort push starts, while ground reaction forces (GRF) and 3D marker trajectories were simultaneously recorded for ground contacts of different sub-sections of the push phase (start acceleration phase: first and second ground contact after the initial push-off from the start block, acceleration phase: 10 m and high-velocity phase: 30 m). To obtain a comprehensive view of the push phase, whole-body kinematics as well as joint kinetics were analysed and compared across the push phase.

Diversity in Medical School, Orthopaedic Surgery Residency, and ACGME-Accredited Foot and Ankle Orthopaedic Surgery Fellowship Training by Gender, Race, and Ethnicity.

Introduction: Increasing diversity in the US health care workforce is a topic of increasing scrutiny and interest. This study analyzes the pipeline of demographic diversity for Accreditation Council for Graduate Medical Education (ACGME)-accredited foot and ankle orthopaedic surgery fellowship training.

Methods: This was a cross-sectional study of medical students, orthopaedic surgery residents, and orthopaedic foot and ankle fellows at US-accredited training programs from 2013 to 2022.

Rhabdomyosarcoma With EWSR1::NF2 Gene Fusion: A Case Report Potentially Expanding Its Genetic Spectrum.

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, presenting with heterogeneous clinical and molecular subtypes. While gene fusions are predominantly associated with alveolar RMS, spindle cell RMS, especially congenital and intraosseous variants, are also linked to specific gene fusions. Furthermore, recently, FGFR1 kinase-driven RMSs were published.

Comparing the Efficacy of a Unique Advanced Bioengineered Type-I Collagen-Based Skin Substitute Versus an Amnion Graft With Standard of Care in the Treatment of Non-healing Diabetic Foot Ulcers: A Randomized Clinical Trial.

The increased cost and morbidity associated with diabetic foot ulcers (DFUs) place a substantial strain on the entire global healthcare system. In this trial, 24 subjects with a chronic DFU, Wagner grade 1 (University of Texas grade 1A), were treated with Standard of Care (SOC) therapy and randomized, one-half to receive advanced high-purity Type-I collagen-based skin substitute (HPTC; manufactured by Encoll Corp., Fremont, CA, USA), and the other half to receive a dehydrated human amnion/chorion membrane (dHACM) or viable cryopreserved human placental membrane (vCHPM).

Delayed diagnosis of posterior tibialis tendon interposition in the distal tibiofibular and tibiotalar joints after open fracture-dislocation of the ankle joint: A case report with a 10-year follow-up.

Irreducible ankle fracture-dislocations due to posterior tibialis tendon (PTT) interposition in the distal tibiofibular and tibiotalar joints are rarely reported, and their diagnoses are often missed and delayed. In addition, previous reports lacked a longer clinical follow-up period, and objective and subjective evaluations of such cases have not been reported. A 22-year-old man sustained an open fracture-dislocation of the ankle joint associated with a distal third of the fibular shaft fracture and diastasis of the distal tibiofibular joint.

Tibiotalocalcaneal nailing as a treatment for ankle fractures in the elderly population: A systematic review.

This study evaluated patient outcomes of tibiotalocalcaneal (TTC) nailing for ankle fractures in an elderly population. A systematic literature search of PubMed and Google Scholar identified 24 studies involving 657 patients aged over 65. Key outcome measures included union rates, healing time, functional scores, and complications.

Radiographic Soft Tissue Thickness is not a Risk Factor for Infection after Primary Total Ankle Arthroplasty.

As the incidence of total ankle arthroplasty (TAA) for the management of end-stage arthritis is on the rise, identification of risk factors for periprosthetic joint infection (PJI) is essential. There has been limited research exploring the use of radiographic soft tissue thickness in TAA despite its predictive value in other forms of arthroplasty. This study evaluated the predictive capabilities of radiographic soft-tissue thickness for PJI following TAA.

Age-related Arterial Stiffening is Associated with A Body Shape Index (ABSI) and Lean Body Mass Index -A Retrospective Cohort Study in Healthy Japanese Population.

Introduction: Several anthropometric indices reflecting cardiometabolic risks have been developed, but the relationship of body composition with arterial stiffness remains unclear. We aimed to determine the interaction between age-related anthropometric changes and progression of arterial stiffness.

Methods: This research analyzed cross-sectional data (N=13,672) and 4-year longitudinal data (N=5,118) obtained from a healthy Japanese population without metabolic disorders.

PFKFB3 decreases α-ketoglutarate production while partial PFKFB3 knockdown in macrophages ameliorates arthritis in tumor necrosis factor-transgenic mice.

Objective: Aberrant 6-phosphofructo-2kinase/fructose-2,6-bisphoshatase 3 (PFKFB3) expression is tightly correlated with multiple steps of tumorigenesis; however, the pathological significance of PFKFB3 in macrophages in patients with rheumatoid arthritis (RA) remains obscure. In this study, we examined whether PFKFB3 modulates macrophage activation and promotes RA development.

Method: Peripheral blood mononuclear cells (PBMCs) from patients with RA, THP-1 cells, and bone marrow-derived macrophages from conditional PFKFB3-knockout mice were used to investigate the mechanism underlying PFKFB3-induced macrophage regulation of RA.

A rare case of ankle peri-implant infection by multi drug resistant Chryseobacterium indologenes.

Chryseobacterium indologenes is a rare human pathogen which is nowadays considered an emerging fearsome organism because of its upcoming antibiotic resistance. We present a quite unique case of a multi drug resistant C. indologenes surgical wound infection in a patient submitted to cannulated screw fixation of a displaced medial malleolus fracture.

The real rotational capacity of the human joints - the muscular and gravitational torques and the foot as a platform.

The purpose was to answer what is the relationship between torques acting on the human body, how does the triceps calf muscle balance the weight of a tilted body and what is the foot's role in the titling body? Two research models were developed. Model 1 - the one-sided lever system consists of a flat bar with, an axis of rotation, used to determine the weight and torque at a given point on it. Model 2 - the two-sided lever system consists of a flat bar imitating a tilted body counteracted by the Achilles tendon, and a platform imitating a foot.

Comparison of Bicortical versus Unicortical Medial Malleolus Fixation.

Background: Ankle fractures continue to increase in incidence and severity in an older, more challenging geriatric population. Medial malleolus fixation with partially threaded cancellous 4.0-mm screws, a common fixation method, has been shown to fail due to pullout strength.