67 results match your criteria: "Ankara Yildirim Beyazit University School of Medicine[Affiliation]"

Mapping of functional erectogenic nerves on the rat prostate.

J Sex Med

December 2024

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.

Background: Preservation of erectogenic nerves during radical prostatectomy (RP) is hampered by limited understanding of their precise localization, due to their complex, intertwined paths, and the inherent individual variations across patients. Because erection utilizes a subset of cavernous nerves (CNs) that in response to sexual stimuli reveal phosphorylation of neuronal nitric oxide synthase (nNOS) on its stimulatory site Ser-1412, we hypothesized that delineation of nerves containing phosphorylated (P)-nNOS on Ser-1412 would establish the location of functional erectogenic nerves within the periprostatic region.

Aim: To identify the distribution and quantity of functional erection-relevant ([P-nNOS]-containing) nerves in the periprostatic area and discriminate them among the CNs distribution.

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Article Synopsis
  • - This study evaluated the effectiveness of plasma and urinary metanephrines as diagnostic tools for adrenal lesions in 152 patients, highlighting their importance in a multidisciplinary medical setting.
  • - A variety of adrenal conditions were identified among patients, including pheochromocytoma and adrenocortical carcinoma, with 94 patients undergoing surgery.
  • - Urinary fractionated metanephrine was found to be the most sensitive test for diagnosing pheochromocytoma (90%), while plasma free normetanephrine was the most specific (91.4%), demonstrating a significant correlation between the plasma and urinary tests.
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Malignant mesenchymal thyroid tumors are one of the rarest types of thyroid cancer. Clinically, these tumors present as a rapidly growing thyroid mass. Due to their rarity and nonspecific findings, they are not the first conditions that come to mind during differential diagnosis.

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Article Synopsis
  • The study evaluates the safety and effectiveness of controlled ovarian stimulation (COS) and oocyte retrieval (OR) in prepubertal and peripubertal patients who are seeking oocyte cryopreservation.
  • Researchers reviewed data from 20 patients aged approximately 15, assessing ovarian function through hormone levels and follicle counts, and found no complications related to the procedures.
  • Results showed a mean retrieval of 5 oocytes, with a maturation rate of 75%, and highlighted the positive relationship between antral follicle count and the number of retrieved oocytes.
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Objectives: To develop two ethical checklists to evaluate (i) management of ethical concerns in research projects and (ii) awareness of ethical conduct of healthcare laboratory professionals.

Methods: Comprehensive discussion among the members of IFCC Task Force on Ethics based on pertinent literature.

Results: This Checklist for Clinical Research Projects should be useful to evaluate research proposals from an ethical perspective before submitting it to an IRB or its equivalent, thereby diminishing rejection rates and resulting in more time-effective projects.

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Inflammatory Bowel Disease (IBD) is mostly characterized by gastrointestinal tract involvement, however can also be accompanied with cardiac manifestations. QRS prolongation and the presence of QRS fragmentation (fQRS) have been previously evaluated in many chronic inflammatory diseases, as an independent predictor of cardiac events. In this study, we aimed to evaluate the QRS duration and fQRS in patients with IBD.

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Background And Study Aims: Nonalcoholic fatty liver disease is the most prevalent chronic liver disease globally and is linked to augmented susceptibility to type 2 diabetes mellitus (DM), cardiovascular disease, and microvascular complications inherent to DM, such as nephropathy, neuropathy, and retinopathy. The fibrosis-4 (FIB-4) scoring system, a noninvasive tool, is useful for predicting the extent of liver fibrosis across diverse pathologies. This study aimed to assess the potential predictive role of FIB-4 scores in microvascular complications associated with diabetes.

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Objective: Many healthcare workers (HCWs) hesitated or refused to receive the COVID-19 vaccines during the pandemic. The attitudes of HCWs toward vaccines have an impact on society and patients. In this study, we aimed to investigate the reasons for vaccine hesitancy and refusal among HCWs during the COVID pandemic.

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Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) syndrome is an extremely rare multisystem disorder with autosomal recessive inheritance and impairs mitochondrial DNA replication, which causes myopathy and neurodegeneration. The classical symptoms of this syndrome are progressive gastrointestinal dysmotility and peripheral neuropathy. We are presenting a patient who had MNGIE syndrome and presented with anejaculation for the first time in the literature.

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Background: This study aims to investigate whether thiol/disulfide homeostasis parameters measurements could be used as a new biomarker to predict the pre- and post-cardiopulmonary bypass oxidative status of pediatric patients undergoing congenital heart surgery.

Methods: A total of 40 children with congenital heart disease (17 males, 23 females; mean age: 39.6±40.

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Background and objective Artificial intelligence (AI) applications such as Chat Generative Pre-Trained Transformer (ChatGPT) created by OpenAI, which represent the revolutionary aspects of today's technology, have benefitted professionals in many fields and society at large. In this study, we aimed to assess how effective is ChatGPT in helping both the patient and the physician manage thyroid nodules, a very common pathology. Methods Fifty-five questions frequently asked by patients were identified and asked to ChatGPT.

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Objective: This study aimed to examine the psychiatric diagnoses, parenting attitudes, family functioning among children and adolescents with epilepsy, coping styles of their mothers, and psychiatric symptoms of their mothers and fathers.

Methods: Forty children and adolescents between the ages of 8 and 18 with epilepsy and 40 healthy controls were included in the study. The clinical interview and other measurements were used to assess psychiatric disorders and familial factors.

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Cavernous nerve mapping methods for radical prostatectomy.

Sex Med Rev

September 2023

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.

Introduction: Preserving the cavernous nerves, the main autonomic nerve supply of the penis, is a major challenge of radical prostatectomy. Cavernous nerve injury during radical prostatectomy predominantly accounts for post-radical prostatectomy erectile dysfunction. The cavernous nerve is a bilateral structure that branches in a weblike distribution over the prostate surface and varies anatomically in individuals, such that standard nerve-sparing methods do not sufficiently sustain penile erection ability.

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Introduction: Tibial slope is a parameter that is important to recognize in knee kinematics and knee surgery. A very wide range of values governing posterior tibial slope exist in the literature. This study is based on the hypothesis that age, gender and region may have an effect on the tibial slope.

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Ileocecal valve that cannot be intubated in Crohn's disease: is this a sign of poor prognosis?

Int J Colorectal Dis

April 2023

Department of Gastroenterology, Ankara City Hospital, Bilkent Avenue, 06800, Cankaya, Ankara, Turkey.

Background: In Crohn's disease (CD), the inability to intubate the ileocecal valve during colonoscopy may be associated with a poor disease prognosis. In this study, we aimed to compare the long-term outcomes of CD patients with and without ileocecal valve intubation during colonoscopy to assess its value as a prognostic parameter.

Methods: This retrospective study involved CD patients with isolated ileal involvement who underwent colonoscopy between 1993 and 2022.

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Background: To evaluate corneal topography and densitometry features in patients with polycystic ovary syndrome (PCOS) and compare them with healthy individuals.

Methods: 53 eyes of 53 female patients diagnosed with PCOS and 53 eyes of 53 age-matched female volunteers were analyzed in the study. In addition to the detailed ophthalmological and gynecological examination, anterior segment analysis was performed using Pentacam.

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Background: Inflammatory bowel disease (IBD), a multisystemic inflammatory disorder, has been associated with increased risk of cardiovascular problems, including complications such as conduction defects and arrhythmias. Therefore, the early assessment of the risk factors predisposing to ventricular arrhythmias is crucial, since it can improve clinical outcomes. The objective of the present study is to evaluate ventricular repolarization by using Tp‑e interval and Tp-e/QTc ratio as candidate markers of ventricular arrhythmias in patients with IBD.

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Objective: In mixed acid-base disorders, it is essential to identify the dominant disorder, either metabolic or respiratory. The calculation of expected partial carbondioxide (pCO2) value obtained from arterial blood gas sample can give a clue to the physician about the main disorder. There are several formulas to calculate the expected pCO2 which are not practical to use and require an arterial blood gas sample.

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Comparison of urgent and early endoscopy for acute non-variceal upper gastrointestinal bleeding in high-risk patients.

Gastroenterol Hepatol

March 2023

Department of Gastroenterology, Ankara City Hospital, Bilkent Avenue, 06800 Çankaya, Ankara, Turkey; Department of Gastroenterology, Ankara Yildirim Beyazit University School of Medicine, Bilkent Avenue, 06800 Çankaya, Ankara, Turkey.

Objective: Data regarding early (within 24h) and urgent endoscopy (within 12h) in non-variceal upper gastrointestinal bleeding (NV-UGIB) revealed conflicting results. This study aimed to investigate the impact of endoscopy timing on the outcomes of high-risk patients with NV-UGIB.

Patients And Methods: From February 2020 to February 2021, consecutive high-risk (Glasgow-Blatchford score ≥12) adults admitted to the emergency department with NV-UGIB were analyzed retrospectively.

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Objectives: The most common complications after radical prostatectomy (RP) are erectile dysfunction (ED) and urinary incontinence (UI). After RP, patients may require endoscopic urethral procedures (EUP) for other urological diseases such as hematuria, urinary system stone disease, and suspicion of bladder tumor. In clinical practice we observed that EUP performed after robot assisted RP (RARP) can cause an increase in the UI level.

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