4 results match your criteria: "Ankara City Hospital Neurology Clinic[Affiliation]"

Introduction: Fingolimod is the first oral immunomodulatory treatment used as secondary care therapy in the treatment of multiple sclerosis for the last 10 years. The objective of our study is to reveal the experiences of the first generic fingolimod active ingredient treatment in different centers across Turkey.

Method: The first generic fingolimod efficacy and safety data of patients followed-up in 29 different clinical multiple sclerosis units in Turkey were analyzed retrospectively.

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Article Synopsis
  • The study investigates genetic counseling and clinical features of Turkish Huntington's disease (HD) patients since 2018, evaluating 141 individuals for symptoms and genetics.
  • Among 84 participants who received counseling, 42% were genetically confirmed to have HD, with a mean onset age of 42.4 years; chorea was the most common initial symptom.
  • Higher CAG repeat numbers correlated with earlier onset and more severe motor symptoms, indicating that paternal inheritance is linked to more severe disease traits, highlighting the need for collaborative management strategies in HD care.
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