1,175 results match your criteria: "Anisocoria"

Oculomotor and trochlear nerve neuritis following botulinum toxin injection for masseter hypertrophy - a case report with literature review.

Eur J Ophthalmol

November 2023

University of Malaya Eye Research Centre (UMERC), Department of Ophthalmology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.

Objective: To report a rare complication of oculomotor and trochlear nerve neuritis following botulinum toxin injection for masseter hypertrophy.

Case Presentation: A previously healthy 31-year-old man presented with a two-week history of left eye (OS) ptosis and diplopia, following botulinum toxin injection over the masseter area for masseter hypertrophy at an aesthetic centre. He had no proptosis or facial asymmetry.

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Asymmetric Bilateral Traumatic Epidural Hematoma: A Report of a Rare Traumatic Lesion.

Korean J Neurotrauma

October 2022

Department of Neurosurgery, Trauma and Burns Center, University of Tunis-El Manar, Faculty of Medicine of Tunis,Ben Arous, Tunisia.

Bilateral epidural hematoma is a rare presentation in head trauma injuries, accounting for only 1%-2% of all epidural hematomas, but with a higher mortality rate than the unilateral form. Herein, we report the case of a 27-year-old man admitted to our department following a road traffic accident. On admission,his Glasgow Coma Scale (GCS) score was 13/15.

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Intimal sarcomas (ISAs) are extremely rare malignant tumors that histologically occur in the tunica intima of large blood vessels of the systemic and pulmonary circulation. Herein, we describe a case of an ISA-based neoplastic aneurysm in the middle cerebral artery (MCA) that resulted in a subarachnoid hemorrhage (SAH). The patient presented to our hospital with severe consciousness disturbance (Glasgow Coma Scale E1V1M2) and anisocoria.

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A 38-year-old woman presented with impaired consciousness and anisocoria due to a subarachnoid hemorrhage and an intracerebral hemorrhage of the left temporal lobe. Examination revealed severe tortuosity in the left middle cerebral artery and three sequential bead-like aneurysms. She underwent a craniotomy in the acute phase to stop rebleeding at the rupture site and remove the intracerebral hematoma.

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A 34 years old female presented with complains of photophobia since 6-7 months. On examination, she had anisocoria of 4 mm in room light which increased in bright light. The left pupil was dilated and unresponsive to direct and indirect light stimuli.

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Here, we report a case of unilateral ocular mydriasis in a pediatric patient with longstanding hyperhidrosis, as well as similar findings in her cat. The patient had been undergoing treatment of her hyperhidrosis with topical glycopyrrolate. This case highlights the potential side effect profile of topical antimuscarinics and the importance of counseling patients on proper precautions.

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Moyamoya disease (MMD) is a rare progressive steno-occlusive cerebrovascular disorder. Currently, revascularization surgery is used as optimal treatment to overcome MMD. However, revascularization for MMD has reported several complications.

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Background: Aneurysm compression, diabetes, and traumatic brain injury are well-known causative factors of oculomotor nerve palsy (ONP), while cases of ONP induced by neurovascular conflicts have rarely been reported in the medical community. Here, we report a typical case of ONP caused by right posterior cerebral artery (PCA) compression to increase neurosurgeons' awareness of the disease and reduce misdiagnosis and recurrence.

Case Summary: A 54-year-old man without a known medical history presented with right ONP for the past 5 years.

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A 5-month-old healthy infant presented with acute flaccid weakness, anisocoria, and urinary retention with clinical suspicion of acute flaccid myelitis versus acute transverse myelitis.

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Apraclonidine-An eye opener.

Front Ophthalmol (Lausanne)

August 2022

Department of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Pharmacological testing with apraclonidine eye drops induces a typical reversal of anisocoria in patients with Horner's syndrome. Moreover, apraclonidine was observed to have an elevating effect on the upper eyelid in Horner's syndrome as well as in healthy subjects, which is thought to be mediated by alpha-1 adrenergic receptors present in the Muller's muscle. We aim to quantitatively investigate the effect of apraclonidine on eyelid position in patients with Horner's syndrome compared to physiological anisocoria based on infrared video recordings from pupillometry.

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Case Series Summary: Three domestic shorthair cats from California presented to veterinary ophthalmologists with immature cataracts. Other presenting clinical signs included corneal edema, anisocoria, anterior uveitis, elevated intraocular pressure, blepharospasm and/or lethargy. All patients were immunocompromised due to concurrent diseases and/or immunomodulatory drugs.

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Kernohan Woltman Notch Phenomenon (KWNP) is caused by a supratentorial lesion pressing the contralateral cerebral peduncle against the free edge of the tentorium of the cerebellum. It is manifested by neurological signs of ipsilateral localization; cerebral MRI is the most sensitive examination for KWNP. Our patient is a 50-year-old woman, operated in 2011 for aortic and mitral valve replacement by mechanical prosthesis, under oral anticoagulant, consults for headaches evolving for 20 days without any notion of head trauma with installation of a progressively worsening left hemibody deficit.

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Background: Adult lead encephalopathy is a rare but critical condition to recognize in modern healthcare settings. Few reports have described the medical and neurosurgical management of severe adult lead encephalopathy.

Case Presentation: A 22 year old woman presented with severe headache, anemia, vomiting, 40-lb weight loss, and constipation.

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Anisocoria and mydriasis after scalp nerve block: a case report.

J Int Med Res

May 2022

Department of Anesthesiology, Second Affiliated Hospital of Army Medical University, PLA, No. 83 Xinqiao Road, Shapingba, Chongqing, China.

Strategies for the assessment of abnormal neurological findings during general anesthesia are limited. However, pupil abnormalities may represent serious neurological complications. We herein present a case of new-onset anisocoria and mydriasis that developed after scalp nerve block.

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Can Quantitative Pupillometry be used to Screen for Elevated Intracranial Pressure? A Retrospective Cohort Study.

Neurocrit Care

October 2022

Department of Clinical Neuroscience, Karolinska Institutet, Central Intensive Care Unit E5:67, Karolinska University Hospital, Stockholm, 17176, Sweden.

Background: Elevated intracranial pressure (ICP) is a serious complication in brain injury. Because of the risks involved, ICP is not monitored in all patients at risk. Noninvasive screening tools to identify patients with elevated ICP are needed.

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Pharmacologic Mydriasis Secondary to Topical Glycopyrronium Tosylate Cloths: Clinical Characterization From a Multicenter Analysis.

J Neuroophthalmol

December 2022

Department of Ophthalmology and Visual Sciences (ARK, SG, PWM, BTJ, KMC), Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois; NorthShore University Health System (JHP), Evanston, Illinois; Department of Ophthalmology (TMJ, NRC), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Neurology (NRC), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Des Peres Eye Center (EC), Des Peres, Missouri; Department of Ophthalmology (EAS), Rush University Medical Center, Chicago, Illinois; Department of Ophthalmology (KCG), University of Cincinnati College of Medicine (KCG), Cincinnati, Ohio; Cincinnati Eye Institute (KCG), Cincinnati, Ohio; and Midwest Retina Consultants (EG-V), Arlington Heights, Illinois.

Background: Topical glycopyrronium tosylate (GT) is an anticholinergic medication for treatment of axillary hyperhidrosis. Pharmacologic mydriasis and anisocoria from topical GT has been reported and may be underrecognized. This study aims to clinically characterize patients presenting with pharmacologic mydriasis from exposure to this medication.

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Anisocoria Due to Ocular Ischemic Syndrome.

J Neuroophthalmol

December 2023

Department of Ophthalmology (ATL, JAD, CEF), University of Washington, Seattle, Washington; and Department of Neurological Surgery (CEF), University of Washington, Seattle, Washington.

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Background: Elderly patients operated for an acute subdural hematoma (ASDH) frequently have a poor outcome, with a high frequency of death, vegetative status, or severe disability (Glasgow Outcome Score [GOS] 1-3). Minicraniotomy has been proposed as a minimally invasive surgical treatment to reduce the impact of surgery in the elderly population. The present study aimed to compare the influence of the size of the craniotomy on the functional outcome in patients undergoing surgical treatment for ASDH.

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Muscular and collagenous cerebellar choristoma in a dog.

J Vet Sci

March 2022

Departamento de Clínica de Pequenos Animais, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil.

This report aims to describe the first case of muscular and collagenous choristoma in a dog. A 10-yr-old female mixed-breed dog presented with lateral recumbence, vocalization, positional vertical nystagmus, divergent strabismus, anisocoria, and status epilepticus. The clinical condition evolved to stupor and ultimately, death.

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Giant Cell Arteritis: Updates and Controversies.

Front Ophthalmol (Lausanne)

March 2022

University of Southern California Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, United States.

Article Synopsis
  • Giant cell arteritis (GCA) is a serious vascular condition mostly affecting older adults, particularly those of Scandinavian descent, but may also be more prevalent in African Americans and Hispanics; it rarely affects Asians and Middle-Eastern individuals.
  • The disease mainly presents with vision issues such as arteritic anterior ischemic optic neuropathy, along with other complications like retinal artery occlusions, and various diagnostic tools are used to identify these manifestations.
  • Diagnosing GCA typically involves a clinical assessment supported by lab tests and imaging, with a temporal artery biopsy (TAB) being the standard method, though newer techniques like ultrasounds may provide quicker and more cost-effective alternatives.
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It is considered a neurological emergency when a patient presents with anisocoria. It is important that the anisocoria whether or not accompanied by the neurological findings. Other reasons of anisocoria should be considered when the absence of neurological or ophthalmological signs such as change of mental status, hemiparesis, ophthalmoplegia, ptosis.

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Objectives: This study retrospectively investigated the prevalence and clinical features of trephine syndrome, which is a late complication of craniectom, in patients who underwent craniectomy decompression.

Methods: Trephine syndrome was defined as an increase of ≥2 points in the functional independent measure (FIM) score at 7 days after cranioplasty compared with that 3 days before cranioplasty. Patients who underwent craniectomy at Kawasaki Medical School Hospital between January 1, 2010, and March 15, 2020, were included in the study.

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Background: Physiological anisocoria is an asymmetry of pupil size in the absence of pathology.

Methods: Images of the pupils under standard illumination were collected in the course of a whole-genome association study of a range of visual functions in 1060 healthy adults. DNA for each participant was extracted from saliva samples.

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Introduction: The management of complex trauma patient with concomitant brain injury and extra-cranial lesions is challenging since the requirement of a low pressure to limit the bleeding clashes with the need to maintain an adequate cerebral perfusion and to obtain a brain CT-scan.Here we present the use of REBOA as a bridge to CT scan in complex head and torso trauma.

Case Presentation: A 59 years old male patient involved in a road traffic crash was admitted to our hospital after a car accident.

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