Multicenter investigation of hemostatic dysfunction in 15 dogs with acute pancreatitis.

Objective: To characterize hemostatic profiles in dogs with acute pancreatitis.

Design: Prospective and observational study.

Setting: Tertiary referral centers.

Thoracic radiographic findings for dogs with cardiac tamponade attributable to pericardial effusion.

Objective: To determine the prevalence of various radiographic findings for dogs with cardiac tamponade (CT) attributable to pericardial effusion (PE) and to determine the sensitivity and specificity of such findings for identification of affected dogs.

Design: Retrospective, randomized, blinded, controlled study.

Animals: 50 dogs with CT attributable to PE and 23 control dogs (10 healthy dogs and 13 dogs with cardiac diseases other than CT).

Assessment of the prevalence of heart murmurs in overtly healthy cats.

Objective: To assess the frequency of heart murmurs in overtly healthy cats.

Design: Prospective study.

Sample Population: 103 healthy domestic cats.

Atrial fibrillation in cats: 50 cases (1979-2002).

Objective: To determine signalment, clinical signs, diagnostic findings, treatment, and outcome for cats with atrial fibrillation (AF).

Design: Retrospective study.

Animals: 50 cats.

Wound healing and management in psittacine birds.

Psittacines and other companion avian species often develop wounds requiring some form of medical or surgical therapy. Advancing technology in the field of wound care and management continues to evolve for use by the veterinary clinician. Although not all wounds can be successfully treated, many can be reduced and minimized with therapy.

Ferret urogenital diseases.

Improved nutrition and client education have decreased the incidence of certain urinary tract diseases in ferrets. Early neutering programs at commercial breeding farms in the United States have also led to a marked decrease in the incidence of reproductive tract disease, especially estrogen-induced bone marrow suppression. However, the increased incidence of adrenal disease and its secondary effects on reproductive and associated urinary tract tissue presents an ongoing challenge for the clinician working with pet ferrets.

Nutritional support in critical care patients.

Malnutrition in the form of insufficient nutrient intake to support tissue metabolism undermines appropriate medical or surgical therapeutic management of a case. The major consequences of malnutrition in all patients are decreased immunocompetence, decreased tissue synthesis and repair, and altered intermediary drug metabolism. A practical goal is to begin nutritional support within 24 hours of the injury, illness, or presentation.

Principles of mechanical ventilation.

Mechanical ventilation is an enormous undertaking for a veterinary hospital in general and for any patient in particular. It is a team effort requiring large amounts of space, supplies, labor, and time. It requires committed owners and clinicians who communicate clearly with each other.

Oxygen therapy and toxicity.

Oxygen (O2) supplementation increases the O2 content of blood, increases the partial pressure of oxygen (PO2) in the capillary blood, and improves tissue delivery of O2. In addition to improving tissue oxygenation, the administration of O2 may improve the function of O2-dependent cellular systems, such as the cytochrome P450 system, which is important to drug and toxin metabolism; nitric oxide synthase, which regulates vasodilation; and host defense systems. Improved tissue oxygenation is also beneficial for wound healing.

Diagnosis of urinary bladder rupture using ultrasound contrast cystography: in vitro model and two case-history reports.

Because urinary bladder rupture can be life threatening, a simple, safe technique for evaluating patients is desirable. Current diagnostic protocols involve radiographic imaging, but ultrasound-based contrast techniques have not been methodically evaluated in veterinary patients with urologic trauma. Ultrasound contrast cystography (contrast cystosonography) involves infusion of microbubbled saline solution through a urinary catheter.

Comparison of liver cytology and biopsy diagnoses in dogs and cats: 56 cases.

The results of liver cytology and corresponding biopsy specimens submitted to the Pathology Department at Angell Memorial Animal Hospital during 1998 were retrospectively reviewed to objectively assess the diagnostic value of liver cytology. A "corresponding" biopsy was defined as a biopsy specimen obtained within 1 day of the cytology specimen. Fifty-six cases were reviewed, including 25 from dogs and 31 from cats.

Meningeal enhancement on magnetic resonance imaging in 15 dogs and 3 cats.

A retrospective study of 15 dogs and three cats was done to characterize the appearance of meningeal enhancement on magnetic resonance (MR) images of the brain, and to correlate this appearance with its underlying cause. Two patterns of meningeal enhancement (pial and dural) were identified. Enhancement of the pia mater was evident in four dogs and one cat, while enhancement of the dura mater was seen in 11 dogs and 2 cats.

Ferret orthopedics.

Orthopedic conditions requiring surgical intervention and correction frequently occur in the ferret patient. Elbow luxations and long bone fractures are among the most common syndromes affecting the ferret patient, which often presents in an emergency setting. Orthopedic conditions in the ferret, as in other mammalian species, are often the result of trauma.

Electrolyte disorders.

Abnormal electrolyte concentrations occur commonly in hospitalized patients and may produce a variety of clinical symptoms, cause lack of response to therapeutics for primary clinical conditions, and affect clinical outcome. Recognition of electrolyte disturbances requires a high index of suspicion by the clinician for such a disturbance and prompt therapy to ensure a positive and timely outcome for the patient. This article discusses electrolyte abnormalities that occur in critically ill patients, with a review of diseases commonly associated with each electrolyte disturbance, and their recommended management.

Cardiovascular pharmacotherapy. Hemodynamic drugs and antiarrhythmic agents.

Successful management of the patient presenting with acute cardiovascular compromise requires a thorough working knowledge of the therapeutic agents available for treatment. This article focuses on the indications for, dosing, and monitoring employed for successful use of the vasoactive agents and antiarrhythmic medications in current widespread use in the veterinary intensive care setting.

Cardiogenic shock and cardiac arrest.

Severe heart disease may cause hypotension and hypoperfusion, and ultimately circulation may cease altogether. These two clinical syndromes are cardiogenic shock and cardiac arrest, respectively. This review summarizes the causes and clinical features of each, and describes the treatment options available to clinicians managing patients in cardiogenic shock.

Pathophysiologic characteristics of hypovolemic shock.

In the late 1800s, while caring for a trauma victim, Warren characterized shock as "a momentary pause in the act of death." A great deal about shock has been discovered since this first description. Dorland's Medical Dictionary defines shock as a condition of profound hemodynamic and metabolic disturbance characterized by failure of the circulatory system to maintain adequate perfusion of vital organs.

An investigation of the relationship between caloric intake and outcome in hospitalized dogs.

Malnutrition in veterinary patients is thought to increase morbidity and mortality, but this has not been statistically quantified. A study was designed to estimate the proportion of hospitalized canine patients in negative-energy balance; relate calories consumed in-hospital to appetite at home shortly after discharge; determine why these dogs were in a negative-energy balance; and assess the relationship between body condition score, physical status score (PSS), diagnosis, and caloric intake with patient outcome. Data were collected from 276 dogs over several days in one of the various referral hospitals.

Emergency and critical care of ferrets.

Gastrointestinal disease, neoplasia, cardiac disease, and endocrinopathy are among the most common syndromes affecting the ferret that presents in an emergency situation. Knowledge of these and other disease processes, indicated diagnostic testing, and immediate treatment protocols are critical to provide efficient and effective care to the ferret in crisis.

Transvenous cardiac pacing.

Transvenous pacing therapy is a life-saving technique for patients with clinically significant bradyarrhythmias. For most symptomatic bradyarrhythmias in small animals, there is no effective substitute for cardiac pacing. The methods employed for pacemaker placement, although potentially time-consuming, are not technically difficult.

Idiopathic hyperostosis of the calvaria in five young bullmastiffs.

A new calvarial hyperostotic syndrome (CHS) in young bullmastiffs is described. Calvarial hyperostotic syndrome clinically resembles canine craniomandibular osteopathy (CMO) and human infantile cortical hyperostosis (ICH), but it is unique in that there is progressive and often asymmetric skull bone involvement, and the population affected appears to be only young, male bullmastiff dogs. Characteristic radiographic findings consist of cortical thickening of the calvaria with irregular, bony proliferation over the frontal, temporal, and occipital bones.

Use of an external skin-stretching device for wound closure in dogs and cats.

Use of an externally applied, noninvasive skin-stretching device in 24 dogs and cats is described. The device uses adhesive-coated pads that are applied to the skin of an animal; pads are positioned on opposite sides of a surgical site and are connected by means of adjustable elastic cables. The cables maintain continuous tension, and cable tension is adjusted and progressively increased at intervals of 6 to 8 hours to promote skin recruitment (stretching), using the cutaneous viscoelastic properties of mechanical creep and stress relaxation.