52 results match your criteria: "Anesthesia Testicle and Epididymis"
Photobiomodulation Improves Histological Parameters of Testis and Spermatogenesis in Adult Mice Exposed to Scrotal Hyperthermia in the Prepubertal Phase.
J Lasers Med Sci
September 2024
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The study investigates how photobiomodulation (PBM) affects the testis of prepubertal male mice exposed to heat stress, which is known to damage testicular health.
- Twenty-four male mice were divided into three groups: a control group, a hyperthermia group, and a hyperthermia plus PBM group, where heat was applied to induce stress and laser therapy was used to assess its protective effects.
- Results showed that the PBM treatment improved sperm quality, increased testicular cell counts, boosted testosterone levels, and reduced harmful oxidative stress, suggesting that laser therapy can help protect the testis from heat damage during critical developmental periods.
Ameliorative effects of sinapic acid against vancomycin-induced testicular oxidative damage, apoptosis, inflammation, testicular histopathologic disorders and decreased epididymal sperm quality.
Reprod Toxicol
October 2024
Department of Medical Biochemistry, Faculty of Medicine, Aksaray University, Aksaray, Turkey.
Article Synopsis
- This study investigated the effects of sinapic acid (SNP) on testicular damage caused by the antibiotic vancomycin (VCM) in male rats, focusing on the properties of SNP as an antioxidant and anti-inflammatory agent.
- Rats were divided into five groups and treated with either VCM, SNP, or a combination, revealing that SNP significantly mitigated oxidative stress markers and preserved testicular histology compared to the VCM group.
- The results indicated that while VCM led to increased sperm damage and altered testicular structure, SNP administration improved antioxidant levels and helped maintain overall testicular health.
[Well-differentiated papillary mesothelial tumour of the tunica vaginalis: A case report].
Beijing Da Xue Xue Bao Yi Xue Ban
August 2024
Department of Urology, Peking University Third Hospital, Beijing 100191, China.
Article Synopsis
- The mesothelium is a layer of cells covering serosal cavities, and mesothelial tumors are rare, especially those in the tunica vaginalis compared to other areas like the pleura or peritoneum.
- Mesothelial tumors in the tunica vaginalis are classified into three categories: adenomatoid tumors, well-differentiated papillary mesothelial tumors (WDPMT), and mesotheliomas, with WDPMT being particularly rare and lacking established treatment guidelines.
- A case of a 29-year-old man with chronic scrotal pain led to an emergency operation, revealing signs consistent with WDPMT, which was confirmed through postoperative histopathology and immunohistochemical staining.
Ameliorative potentials of diosmin and hesperidin fractions on chlorpyriphos-induced changes in reproductive hormones, sperm characteristics, and testicular glycogen in male Wistar rats.
Naunyn Schmiedebergs Arch Pharmacol
November 2024
Federal University of Agriculture (College of Veterinary Medicine), Abeokuta, Ogun, Nigeria.
Article Synopsis
- Pesticide exposure, specifically from Chlorpyriphos, causes significant reproductive issues in male rats by damaging their sex organs and reducing hormone levels, sperm quality, and testicular glycogen.
- The study examined the effect of flavonoids (diosmin and hesperidin) on recovering reproductive functions in male Wistar rats after they were exposed to Chlorpyriphos for 60 days.
- Results showed that the rats treated with flavonoids had notably better levels of reproductive hormones, improved sperm parameters, and higher testicular glycogen compared to those treated only with Chlorpyriphos, indicating the potential protective effects of these antioxidant compounds against pesticide toxicity.
[Effects of oral exposure to iron oxide nanoparticles on reproductive system of male rats].
Wei Sheng Yan Jiu
May 2024
West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Article Synopsis
- The study aimed to examine how oral exposure to iron oxide nanoparticles (Fe₂O₃NPs) affects male rat reproduction.
- Forty rats were divided into control and three dose groups, receiving different amounts of Fe₂O₃NPs for 28 days, with measures taken on body weight, reproductive organ weights, and sperm analysis.
- Results showed significant disorganization in sperm production and increased sperm deformities in higher dose groups, but no major changes in overall body weight or certain enzyme activities were observed.
A case of liposarcoma of the spermatic cord.
Urol Case Rep
July 2024
Department of Urology, LA RABTA Hospital, University of TUNIS EL MANAR, Tunis, Tunisia.
Article Synopsis
- Para-testicular liposarcoma is a rare type of cancer that arises from the fatty tissue around the spermatic cord, affecting the testicle and epididymis.
- A case study details a 58-year-old African man who had a sizable tumor on his right spermatic cord.
- Surgical treatment involved a right orchidectomy and extensive tumor removal, and analysis of the specimen confirmed it as paratesticular liposarcoma.
The role of cur ole of curcumin against paclitax cumin against paclitaxel-induced o el-induced oxidativ xidative stress and DNA damage in testes of adult male rats.
Turk J Med Sci
February 2023
Department of Histology and Embryology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.
Article Synopsis
- Paclitaxel is a common cancer treatment known to harm the male reproductive system, prompting research into ways to mitigate its toxic effects using antioxidants like curcumin.
- A study involving 40 male rats tested the protective effects of curcumin against paclitaxel-induced testicular damage, comparing different treatment groups (control, curcumin only, paclitaxel only, and a combination of curcumin and paclitaxel).
- Results showed that curcumin significantly reduced testicular damage and improved testosterone levels in the group receiving both curcumin and paclitaxel, indicating a potential protective role for curcumin in mitigating paclitaxel's adverse effects on the testes.
Nerve and Glial Cell Expressions in the Testes and Epididymides of Different Age Groups of Cane Rat ().
J Microsc Ultrastruct
January 2021
Department of Veterinary Anatomy, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Article Synopsis
- - This study explored how the presence of neuronal and glial cell markers changes in cane rats of different ages by using specific staining techniques on their testes and epididymides.
- - Researchers analyzed 32 male cane rats across four age groups, assessing structures in the testes and epididymis after anesthetizing the animals and applying histochemical methods.
- - Findings revealed that both neuronal and glial cell expressions increased with age, indicating a potential link between these variations and heightened reproductive activity in cane rats.
Repeated Doses of Ketamine Affect the Infant Rat Urogenital System.
Drug Des Devel Ther
October 2021
Medical Faculty, Department of Biochemistry, Gazi University, Ankara, Turkey.
Article Synopsis
- - This study investigates the impact of long-term ketamine use on various organs, specifically focusing on potential damage to the kidneys, testicles, epididymis, and ductus deferens, in addition to the previously known bladder issues.
- - Male Wistar Albino rats were divided into two groups, one receiving ketamine and the other saline, for three weeks, after which their kidney and testicular tissues were analyzed for biochemical and histopathological changes.
- - Results indicated significant kidney and testicular damage in the ketamine group, marked by increased tissue congestion and altered enzyme activity, suggesting further clinical and research exploration is needed regarding the effects of repeated ketamine administration in medical settings.
Research on the protective effect of caffeic acid phenethyl ester on testicular damage caused by cisplatin.
Turk J Med Sci
December 2020
Department of Histology and Embryology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Article Synopsis
- Cisplatin (CP), a chemotherapy drug, causes severe damage to male reproductive cells in rats, which prompted a study to explore if caffeic acid phenethyl ester (CAPE), found in propolis, could protect against such damage.
- The experiment involved four groups of rats: a control group, a CP-only group, a CP + CAPE group, and a CAPE-only group, with various treatments over 12 days followed by analysis of testicular health and testosterone levels.
- Results showed that rats given CAPE along with CP had significantly reduced testicular damage, lower levels of the harmful compound malondialdehyde, and improved enzyme and testosterone levels, indicating CAPE's potential protective effects against CP-induced testicular damage
The theoretical method and clinical application of testicular torsion.
Int Urol Nephrol
June 2020
Department of Ultrasound Imaging, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 of Nanlishi road, Xicheng District, Beijing, 100045, China.
Article Synopsis
- This study examined methods to reduce testicular torsion, focusing on the elastic retraction and push-and-turn techniques in a clinical setting.
- Out of 28 patients treated, 22 received manual reduction, achieving an 86.36% success rate, with 19 patients successfully restored, showing improved pain relief and blood flow to the affected testis.
- The findings suggest that these manual techniques could enhance treatment success and should be taught to primary care hospitals to preserve testicular function and reduce the need for surgery.
Ameliorating effects of agomelatine on testicular and epididymal damage induced by methotrexate in rats.
J Biochem Mol Toxicol
March 2020
Department of Clinical Biochemistry, Antalya Education and Research Hospital, Antalya, Turkey.
Article Synopsis
- The study aimed to explore if agomelatine (AGO) can prevent damage to testicular and epididymal tissues caused by methotrexate (MTX) in rats.
- Twenty-four male Wistar albino rats were divided into three groups: a control group, an MTX-only group, and an MTX+AGO group, which received AGO after MTX.
- Results showed that MTX led to significant tissue damage, increased oxidative stress, and inflammatory responses, while AGO treatment improved these harmful effects and helped restore normal tissue conditions.
Effects of lidocaine on equine ejaculated sperm and epididymal sperm post-castration.
Theriogenology
August 2019
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, 1 Garrod Drive, Davis, CA, 95616, USA. Electronic address:
Article Synopsis
- * They hypothesized that higher doses of lidocaine would negatively impact various sperm parameters, including progressive motility and membrane integrity.
- * Results indicated that lower lidocaine concentrations (1 μg/ml and 10 μg/ml) did not significantly affect sperm, but higher concentrations (100 μg/ml and above) led to notable decreases in motility and membrane integrity, while morphology remained unchanged.
Effect of Electroacupuncture on Spermatogenesis in Rats with Oligozoospermia of Insufficiency of Shen (Kidney) Essence Syndrome.
Chin J Integr Med
April 2019
Department of Andrology, China-Japan Friendship Hospital, Beijing, 100029, China.
Article Synopsis
- The study aimed to evaluate the impact of electroacupuncture (EA) on cytoskeletal protein expression in Sertoli cells and sperm production in rats with a specific fertility issue called oligozoospermia.
- Twenty healthy male rats were divided into four groups to compare normal conditions, treatment with a drug (tripterygium glycosides), a sham procedure, and actual EA treatment at specific acupuncture points over 30 days.
- Results showed that EA treatment significantly improved sperm count and movement, increased specific proteins in Sertoli cells, and reduced cell death in germ cells compared to the other groups, indicating its positive effect on fertility.
Article Synopsis
- - Intracytoplasmic sperm injection (ICSI) helps men with severe infertility issues like azoospermia by allowing sperm retrieval directly from the epididymis or testis for potential biological parenthood.
- - The review explores the evolution of surgical sperm retrieval techniques, detailing their use for both azoospermic and non-azoospermic men, as well as the technical details involved in these methods.
- - Additionally, it evaluates the success rates of ICSI with non-ejaculated sperm and discusses the implications for the health of the resulting children.
Investigations into the Risk of Reproductive Toxicity Following Exposure to Highly Active Anti-Retroviral Drugs in Rodents.
Tokai J Exp Clin Med
July 2018
Department of Pharmacology, Therapeutics and Toxicology, College of Medicine, University of Lagos, Lagos-Nigeria P.M.B 12003, Lagos-Nigeria. or
Article Synopsis
- The introduction of Highly Active Antiretroviral Therapy (HAART) has significantly reduced HIV/AIDS-related illness and death, but it may cause harmful side effects due to its toxicity.
- A study examined the impact of HAART on reproductive hormones and organs in male and female rats, revealing significant reductions in reproductive metrics like hormone levels, sperm quality, and ovarian follicle counts.
- The findings suggest that both single and combination antiretroviral drugs can lead to reproductive toxicity, highlighting the need for further research on their effects.
Article Synopsis
- * Fifty male guinea pigs were divided into five groups; different doses of saline, CaCl2, and VCM were administered to assess impacts on sperm production and hormone levels, with a focus on determining effective sterilization without significant health risks.
- * Results showed a decrease in epididymal sperm count across treatment groups, with Group V exhibiting azoospermia and altered hormone levels; histopathological analysis indicated no signs
Retained fertilizing capability in cryopreserved feline spermatozoa.
Reprod Domest Anim
April 2017
Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Article Synopsis
- * In endangered felids, efforts to recover viable sperm from the epididymis and testis are ongoing to enhance future breeding opportunities; sperm from the caudal epididymis has shown some success, but recovery methods and storage conditions are critical for preserving DNA quality.
- * Studies indicate that while sperm from ejaculated and epididymal sources maintain better DNA integrity during cold storage and cryopreservation, testicular sperm often suffers damage, leading to lower fertilization success
A Minimally Invasive Method in Diagnosing Testicular Torsion: The Initial Experience of Scrotoscope.
J Endourol
June 2016
Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China .
Article Synopsis
- The study aimed to evaluate the effectiveness of scrotoscopy for diagnosing testicular torsion in patients aged 12 to 24 who presented with acute scrotal pain.
- In the research, 14 patients were assessed using both Doppler ultrasound and a 10F pediatric cystoscope, resulting in a 100% diagnostic accuracy for scrotoscopy, compared to 77.8% for ultrasound.
- The findings suggest that scrotoscopy is a minimally invasive and reliable method for early detection of testicular torsion, with no observed complications during the procedure.
Intratesticular and intraepididymal injections to sterilize male cats: From calcium chloride to zinc gluconate and beyond.
J Feline Med Surg
September 2015
Associate Professor of Companion Animal Industries, Department of Animal and Rangeland Sciences, Oregon State University, Corvallis, Oregon, USA
Article Synopsis
- * Sclerosing agents like calcium chloride dihydrate, zinc gluconate, and chlorhexidine digluconate have been used for these injections; however, there's a lack of standardization in dosage and application.
- * Both injection methods do not fully reduce testosterone production and typically require sedation, making them less desirable for pet cats compared to castration, with the potential for residual fertility to last for 1-2 months post-treatment.
[Scrotal desmoid tumor in a patient with familial adenomatous polyposis].
Hinyokika Kiyo
January 2015
The Department of Diagnostic Pathology, Osaka Red Cross Hospital.
Article Synopsis
- * Colonoscopy revealed multiple adenomatous polyps and colon cancer, leading to a diagnosis of familial adenomatous polyposis, and a CT scan showed a tumor in the scrotum.
- * The patient underwent surgery to remove the scrotal mass and part of the corpus cavernosum penis, which was identified as a desmoid tumor, and he has been disease-free for 24 months post-surgery.
Effects of vasectomy on seminal plasma alkaline phosphatase in male alpacas (Vicugña pacos).
Reprod Domest Anim
December 2013
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA; Center for Reproductive Biology, Washington State University, Pullman, WA, USA.
Article Synopsis
- Azoospermia, a condition of infertility in male alpacas, poses a diagnostic challenge in distinguishing between testicular and non-testicular causes.* -
- This study tested the use of alkaline phosphatase (AP) levels in seminal plasma to differentiate the origins of azoospermia by conducting an experiment on 22 male alpacas with induced bilateral outflow obstruction.* -
- The results showed that while AP levels decreased post-surgery in most animals, the assay was not reliable for determining the cause of azoospermia, indicating that a testicular biopsy remains the best diagnostic option.*
Prospective randomised controlled trial comparing sub-epididymal orchiectomy versus conventional orchiectomy in metastatic carcinoma of prostate.
Indian J Surg
June 2011
Ratna Memorial Hospital, Pune, 411053 Maharashtra India.
Article Synopsis
- Androgen blockade through surgical castration is common for patients with metastatic prostate cancer, and this study compares two techniques: sub-epididymal orchiectomy and total orchiectomy.
- The study involved 60 patients who were randomly assigned to either procedure, measuring outcomes like serum testosterone levels, surgery duration, and patient satisfaction after the surgeries.
- Results showed that both procedures effectively lowered testosterone to castrate levels, but patients who underwent sub-epididymal orchiectomy reported significantly higher satisfaction scores and found it a simpler, safer option suitable for outpatient treatment.
Epididymis ligation: a minimally invasive technique for preparation of teaser rams.
Vet Surg
January 2010
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Article Synopsis
- A minimally invasive technique for preparing teaser rams involves using a needle-assisted ligation method to block the epididymis without causing external wounds or extensive recovery needs.
- The study involved six mature rams and showed that the ligation effectively resulted in no motile or live sperm in ejaculates after three weeks, without affecting the rams' attraction or libido towards ewes.
- This technique is deemed simple and adaptable for use in other animal species, offering a practical alternative for veterinary practices.
Open epididymal sperm aspiration (OESA): minimally invasive surgical technique for sperm retrieval.
Arch Esp Urol
April 2006
Department of Urology, Institute H. S. Raffaele, Milan, Italy.
Article Synopsis
- The study explores a new technique for sperm retrieval called OESA, used for treating male infertility caused by obstructive azoospermia, comparing it with existing methods like MESA, TESE, and PESA.
- Over a period from 1998 to 2003, 153 sperm retrieval procedures were conducted; OESA was successful in 78 cases, while TESE was performed in 75 instances when OESA failed.
- The results showed higher sperm retrieval counts and pregnancy rates of 26.6% for OESA versus 6.4% for TESE, indicating OESA's effectiveness and safety, with no reported complications.