4,628 results match your criteria: "Anesthesia Local with Sedation"

Advances in foetal anaesthesia.

Best Pract Res Clin Anaesthesiol

June 2024

Department of Anaesthesiology, UZ Leuven, Department of Cardiovascular Sciences, Group Biomedical Sciences, KU Leuven, Herestraat 49, 3000, Leuven, Belgium. Electronic address:

Article Synopsis
  • Advances in antenatal ultrasound have led to earlier detection of congenital anomalies, prompting research into foetal surgery to treat these conditions.
  • Surgical interventions can be minimally invasive with local anaesthesia or involve open procedures requiring general anaesthesia to manage pain and optimize conditions.
  • While administering anaesthesia directly to the foetus or through the mother can alleviate pain, animal studies suggest potential risks to foetal brain development, complicating its clinical application.
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  • The study evaluated the feasibility and safety of monitored anesthesia care (MAC) versus intubated general anesthesia (IGA) for cardiac surgery involving cardiopulmonary bypass (CPB).
  • A total of 11 patients received MAC while 13 received IGA, with no major complications in either group, and both groups showed similar demographic and operative characteristics.
  • Results indicated that MAC led to lower opioid use, quicker resumption of oral intake, and reduced ICU length of stay, suggesting MAC may improve postoperative recovery compared to IGA.
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Ischemic stroke, caused by the interruption of the blood supply to the brain, requires prompt medical intervention to prevent irreversible damage. Anesthetic management is pivotal during surgical treatments like mechanical thrombectomy, where precise strategies ensure patient safety and procedural success. This narrative review highlights key aspects of anesthetic management in ischemic stroke, focusing on preoperative evaluation, anesthetic choices, and intraoperative care.

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Electroencephalographic depression after abruptly increasing partial pressure of end-tidal carbon dioxide: a case series.

BMC Anesthesiol

October 2024

Laboratory of Anesthesia and Critical Care Medicine, West China Hospital, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Sichuan University, Chengdu, 610041, China.

Article Synopsis
  • Prolonged electroencephalographic (EEG) depression during surgery is linked to negative patient outcomes, but there's limited research on how sudden increases in carbon dioxide levels affect EEG.
  • In a case study of four patients undergoing laparoscopic liver surgery, EEG monitoring revealed a notable depression in EEG activity shortly after a rise in carbon dioxide levels, indicated by slower frequencies and reduced EEG amplitude.
  • The findings suggest that anesthesiologists should be vigilant for EEG depression during sudden increases in carbon dioxide, recommending the use of EEG monitoring in patients at risk of elevated carbon dioxide levels.
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Adult Simultaneous Cochlear Implantation: Local Anesthesia.

Ear Nose Throat J

October 2024

King Abdullah Ear Specialist Center, College of Medicine, King Saud University Medical City (KSUMC), King Saud University, Riyadh, Saudi Arabia.

: Cochlear implant (CI) surgery is conventionally done under general anesthesia (GA). However, many patients are unable to undergo GA due to various reasons, raising the need for an alternative safe option. CI under local anesthesia is feasible and safely done in patients who can't tolerate GA.

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  • This study explores the safety and effectiveness of combining local infiltration anesthesia (LIA) with monitored anesthesia care (MAC) for patients with end-stage renal disease undergoing peritoneal dialysis catheter placement.
  • Conducted as a retrospective analysis of 123 ESRD patients, it compares two anesthesia methods: LIA alone versus LIA combined with MAC, which includes preoperative sedation and intraoperative analgesia.
  • Results indicate that the LIA + MAC group experienced significantly lower pain levels during and after surgery compared to the LIA group, along with a shorter surgical duration.
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  • A study was conducted to compare the effects of intrathecal bupivacaine combined with either fentanyl or midazolam for patients undergoing lower abdominal and limb surgeries, involving 60 participants divided into two groups.
  • Group F received bupivacaine and fentanyl, while Group M received bupivacaine and midazolam, with outcomes measured in terms of onset time and duration of sensory and motor blocks.
  • Results showed that Group F had significantly longer sensory and motor blockade durations and quicker onset times compared to Group M, as well as better overall analgesia.
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Background: Lengthening of the extensor hallucis longus (EHL) is performed to address various forefoot pathologies. The retraction of this tendon is strongly associated with the Hallux Abductus Valgus (HAV) deformity. Minimally Invasive Surgery (MIS) lengthening of the EHL is carried out in combination with other surgical techniques for HAV bone realignment.

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Thermo-expandable intraprostatic nitinol stents in the treatment of bladder outlet obstruction: a consecutive case series.

Scand J Urol

October 2024

Department of Urology, Copenhagen University Hospital - Herlev & Gentofte Hospital, Gentofte, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Objective: In high-risk patients, prostatic stents may alleviate obstruction at the prostate level. Since 2020 we have used thermo-expandable intraprostatic nitinol stents. Here we document outcomes through the first years with the procedure.

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Transient bradycardia during local anaesthesia to the oral cavity under intravenous sedation and its associate factors: a prospective observational study.

BMC Oral Health

October 2024

Department of Dental Anesthesiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8549, Japan.

Background: Local anaesthesia in dental procedures is generally safe, although the occurrence of transient bradycardia (TB) has occasionally been reported. TB is often associated with two reflexes, the trigeminal cardiac reflex (TCR) and the vasovagal reflex (VVR) and is characterised by a rapid decrease in heart rate (HR) and blood pressure (BP). The prevalence of TCR is considered low, and its predictors have not been thoroughly investigated, although an association with the gag reflex has been suggested in recent years.

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Introduction: This study was aimed to evaluate the feasibility, safety, and advantages of the use of transurethral intraprostatic anesthesia (TUIA) using Schelin Catheter (SC) in patients undergoing holmium laser enucleation of the prostate (HoLEP).

Material And Methods: TUIA was performed using SC, a catheter equipped with an operative channel with a retractile needle, a standard drainage outlet, and a balloon port. After inserting the SC into the patient's urethra and filling the balloon to anchor it in the bladder neck, four target injections with local anesthetic were performed, one in each quadrant in the base area of the prostate.

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Objective: Uncooperative behavior in pediatric dentistry is one of the most common manifestations of dental anxiety. Managing anxious patients can be attained by moderate sedation. This study aimed to compare the effect of sedation by dexmedetomidine-ketamine combination (DEX-KET) versus dexmedetomidine (DEX) on behavior of uncooperative pediatric dental patients.

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Article Synopsis
  • - Clonidine, an α2 agonist, improves hypotensive and analgesic outcomes when added to scalp blocks during surgery, particularly enhancing ropivacaine's effectiveness for postoperative pain management.
  • - A study involved 60 ASA grade I and II patients undergoing supratentorial craniotomy, divided into two groups: one receiving ropivacaine alone and the other receiving ropivacaine with clonidine.
  • - Results showed that the combination of ropivacaine and clonidine significantly prolonged analgesia duration (9.10 hours vs. 4.30 hours) and reduced tramadol consumption compared to the ropivacaine-only group, with notable differences in blood pressure readings.
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  • This retrospective study examined the effects of sedation with remimazolam versus dexmedetomidine during awake endotracheal intubation (AEI) in 98 patients undergoing scoliosis correction surgery.
  • Results showed that dexmedetomidine caused greater reductions in mean arterial pressure (MAP) and heart rate (HR) compared to remimazolam, but remimazolam led to a smaller increase in MAP during intubation.
  • Ultimately, both sedatives allowed for successful AEI with local anesthesia, but remimazolam provided more stable hemodynamics for patients.
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Is the combination of interfascial plane blocks sufficient for awake breast cancer surgery? An observational, prospective, proof-of-concept study.

BMC Anesthesiol

September 2024

Department of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, Samsun Training and Research Hospital, Barış Bulvarı Kadıköy Mahallesi No : 199 PK : 55090 İlkadım, Samsun, Turkey.

Article Synopsis
  • Breast cancer surgery often requires anesthesia, with awake surgery gaining traction due to risks associated with general anesthesia and patient preference.
  • A study from July 2022 to July 2023 tested ultrasound-guided fascial plane blocks for anesthesia in awake breast surgeries, enrolling 17 patients who met specific criteria.
  • Results showed that 15 out of 17 patients achieved effective anesthesia, with high satisfaction rates and no complications, suggesting this method could reduce the need for general anesthesia in breast cancer surgeries.
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  • This study investigates the impact of cervical plexus block (CPB), combined with local anesthesia and sedation, on post-operative pain in patients undergoing thermal ablation (TA) of thyroid nodules.
  • Patients were divided into two groups: one receiving standard pain management without CPB and the other receiving CPB, with results showing significantly lower pain scores immediately and four hours after the procedure in the CPB group.
  • The study concludes that adding CPB improves pain control without affecting recovery quality or discharge timing, indicating it's a beneficial addition to the pain management regimen for thyroid ablation patients.
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Purpose: This study aimed to evaluate the efficacy and safety following treatment with Bulkamid for stress urinary incontinence (SUI) or stress-predominant mixed urinary incontinence (MUI).

Methods: We retrospectively analyzed data of women diagnosed with SUI or stress-predominant MUI who underwent Bulkamid periurethral injection between November 2020 and January 2023 and completed 12 months of follow-up. The primary outcome of the study was to assess patient satisfaction, which was measured on a four-point scale, ranging from cured to worse, and through validated questionaries such as the International Consultation on Incontinence Questionnaire-short Form (ICIQ-UI SF) and Contilife Quality of Life questionnaire.

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Background: Fear and anxiet are significant barriers of dental care in children. Sedation emerged as a valuable behaviour guidance technique to manage uncooperative children.

Aim: To evaluate the sedative and behavioral effectiveness of midazolam administered via nebulizer in comparison with intranasal atomizer in the behavior management of anxious children during dental treatment.

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The search for the ideal pain management strategy after knee arthroscopy continues. For patients unable to receive regional anesthesia, peri-articular or intra-articular injections of local anesthetics with other medications offer a promising solution. Dexmedetomidine (a short-term sedative analgesic marketed under the names Dexdor and Precedex), when added to local anesthetics, may offer an increase in the length of time between surgery and the need for a rescue analgesic agent.

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This study assesses the efficacy of the quadratus lumborum block (QLB) in the management of procedural and periprocedural pain associated with small renal mass cryoablation. To the best of our knowledge, this is the first study that examines the use of QLB for pain management during percutaneous cryoablation of renal cell carcinoma (RCC). A single-center retrospective review was conducted for patients who underwent cryoablation for RCC with QLB between October 2020 and October 2021.

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Introduction: Managing blood pressure in patients with large vessel occlusion affects infarct size and clinical outcomes. We examined how restoring blood flow impacts systemic blood pressure during mechanical thrombectomy.

Patients And Methods: Patients with large vessel occlusion in the anterior circulation undergoing mechanical thrombectomy between June 2016 and January 2018 were screened.

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Introduction: In stroke patients with acute large vessel occlusion, endovascular therapy (EVT) may be performed with or without sedation. Our aim is to describe self-reported intraprocedural comfort in patients undergoing EVT depending on sedation type.

Methods: We performed a prospective observational single-center study of patients undergoing EVT.

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Objective: To prospectively assess surgical outcomes, complications, and patient-reported tolerability of invasive scrotal surgeries under local anesthesia (LA) alone, without sedation, compared to tolerability of penile procedures commonly performed in this manner.

Methods: Adult patients undergoing penile and scrotal surgeries under LA only were enrolled from August 2022 to June 2023 (NCT05617261). Demographics, surgeon-perceived and patient-reported pain, and surgical variables were collected.

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Article Synopsis
  • Percutaneous ultrasound-guided radiofrequency ablation (RFA) is an effective treatment for liver tumors like hepatocellular carcinoma (HCC) and colorectal liver metastases (CRLMs), with sedation being crucial for a safe procedure.
  • A retrospective study involving 35 patients showed that RFA was done without any anesthesia-related complications, using a step-up sedation approach, leading to excellent local tumor-free survival rates within one to six months.
  • The findings suggest that performing RFA in a non-operating room anesthesia (NORA) setting is well-tolerated by patients and results in positive postoperative and oncological outcomes.
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Objective: This study aimed to investigate whether the administration of intrathecal dexmedetomidine as a bupivacaine adjuvant for caesarean section can prolong the duration of analgesia compared with bupivacaine alone. Secondary outcomes included postoperative pain, the time interval to the first analgesic request, the level of sedation, the incidence of adverse effects, and the fetal outcomes.

Materials And Methods: A systematic review and meta-analysis were conducted.

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