171 results match your criteria: "Anagen Effluvium"
The Proportion of Catagen and Telogen Hair Follicles in Occipital Scalp of Male Androgenetic Alopecia Patients: Challenging the Established Dogma.
Exp Dermatol
October 2024
Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Article Synopsis
- Hair follicles undergo a continuous cycle of growth (anagen), regression (catagen), and rest (telogen), with the time spent in each phase affecting hair length and health.
- Traditional beliefs suggest that 85%-90% of hair follicles are in the growth phase, but recent studies indicate that these values may not be accurate due to flaws in assessment methods.
- A new examination of hair follicles during hair transplants revealed that catagen follicles (7.5%) are more prevalent than previously thought, challenging the established belief about the distribution of hair follicles in different stages.
Hair Loss: Diagnosis and Treatment.
Am Fam Physician
September 2024
Boston University Chobanian and Avedisian School of Medicine, Boston, MA.
Article Synopsis
- Over 80 million people in the U.S. experience hair loss, classified mainly as nonscarring alopecias (diffuse, patterned, or focal), with androgenetic alopecia being the most common.
- Treatment options vary: minoxidil is the first line for patterned hair loss, while focal hair loss may require corticosteroids or oral antifungals depending on the cause.
- Hair loss can lead to anxiety, depression, and lower quality of life, emphasizing the importance of patient education on treatment options and realistic expectations.
The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology.
Skin Appendage Disord
August 2024
Dr. Philip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Article Synopsis
- Environmental exposures negatively affect hair follicles (HFs), which are sensitive to contaminants absorbed through the skin or circulated in the bloodstream.
- Pollutants like particulate matter can cause inflammation and are linked to hair loss conditions such as alopecia areata, while substances like tobacco smoke and heavy metals also impact hair health.
- Research on how these environmental factors affect hair pathology is ongoing and highlights the need for more in-depth studies.
[Alopecia due to chemotherapeutics, hedgehog inhibitors, targeted antibody therapies and immune checkpoint inhibitors : Pathogenesis, clinical picture, diagnostics and prophylaxis].
Dermatologie (Heidelb)
June 2024
Campus Kiel, Klinik für Dermatologie und Venerologie, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.
Article Synopsis
- * Chemotherapy-induced hair loss is quite common, affecting up to 65% of patients, often starting 1-3 weeks into treatment, but it is usually reversible.
- * Preventative measures like scalp cooling can be effective during chemotherapy, and it's recommended to connect patients early with support groups and resources for wigs if hair loss is anticipated.
Cutaneous Reactions Following Anticancer Drug Therapy in a Tertiary Care Centre.
JNMA J Nepal Med Assoc
January 2024
Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.
Article Synopsis
- Cutaneous reactions are skin issues that can occur after cancer treatment, varying from mild to severe, impacting patients' quality of life.
- A study at a tertiary care center from October 2021 to December 2022 found a prevalence of 2.22% among 3,288 patients, with anagen effluvium being the most common reaction.
- The overall occurrence of these skin reactions was lower than in other similar studies, suggesting a need for better identification and management of these side effects in cancer treatment plans.
Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin B12 levels.
North Clin Istanb
January 2024
Department of Dermatology and Venereal Diseases, Firat University Faculty of Medicine, Elazig, Turkiye.
Article Synopsis
- Telogen effluvium (TE) is a common type of hair loss in women, influenced by factors like stress, nutritional deficiencies, and hormonal imbalances.
- A study involving 108 female patients aimed to compare blood biochemical markers with findings from digital phototrichograms to better understand diffuse hair loss.
- Results showed that while serum biochemical parameters were normal, the hair pull test indicated a higher incidence in chronic TE, and lower ferritin levels were associated with an increased telogen ratio, suggesting a link between nutritional status and hair loss.
Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
J Cosmet Dermatol
April 2024
Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Article Synopsis
- Non-scarring alopecia encompasses various types of hair loss, including androgenetic alopecia and alopecia areata, with mixed findings regarding the role of vitamin D levels in these conditions.
- A meta-analysis of 23 studies involving over 10,000 participants found that patients with non-scarring alopecia had significantly lower serum 25-hydroxyvitamin D levels and higher rates of vitamin D deficiency compared to healthy individuals.
- The study suggests that vitamin D supplementation could be beneficial for individuals suffering from non-scarring alopecia.
and Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/β-Catenin Signaling Pathway.
Curr Issues Mol Biol
October 2023
Department of Convergence Korean Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Article Synopsis
- The YH complex, a new formula containing specific ingredients, was studied for its effects on hair growth and potential molecular mechanisms.
- Results showed that it promoted hair regrowth and increased hair thickness in mice with hair loss, along with enhancing the proportion of hair follicles in the growth phase.
- The study revealed that YH complex boosts growth factors and activates the Wnt/β-catenin signaling pathway, suggesting it could be a viable treatment for various types of hair loss disorders.
Trichoscopic Patterns and Confocal Microscopy Features of Chemotherapy-Induced Alopecia.
Skin Appendage Disord
October 2023
Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Article Synopsis
- Chemotherapy-induced alopecia (CIA) can significantly impact cancer patients' quality of life, yet its detailed features have not been extensively studied.
- This research examined the trichoscopic and reflectance confocal microscopy (RCM) characteristics of CIA in 24 patients (19 females and 5 males) who recently underwent chemotherapy.
- Findings revealed specific trichoscopic traits, including features of anagen effluvium, but with varied dot appearances, indicating that chemotherapy causes intermittent damage to hair follicles and affects hair production; however, more extensive studies are needed for confirmation.
Dermatological perspectives on pressure alopecias: A call for awareness.
J Am Acad Dermatol
April 2024
Trichology Clinic, Department of Dermatology, Hospital General Dr. Manuel Gea González, Mexico City, Mexico. Electronic address:
Medication-induced hair loss: An update.
J Am Acad Dermatol
August 2023
The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, New York. Electronic address:
Article Synopsis
- - Drug-induced hair loss can result from various medications, including cytotoxic agents, biologics, and immunomodulating agents.
- - The article highlights how to diagnose and manage alopecia caused by these drugs.
- - There is a particular emphasis on recently identified medications that may contribute to hair loss.
A Rare Type of Radiation-Induced Alopecia: Proton-Induced Alopecia.
Skin Appendage Disord
August 2023
Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Article Synopsis
- Radiation-induced alopecia (RIA) can occur after cranial radiation therapy, often leading to permanent hair loss, and proton-induced alopecia (PIA) is a rare subtype associated with proton therapy for brain tumors.
- A case study of a 38-year-old woman shows she experienced widespread hair loss in the frontal area after receiving proton therapy for a meningioma, where trichoscopy revealed various types of hair damage.
- Following a diagnosis of PIA, the patient was treated with minoxidil, resulting in total hair regrowth within 4 months, highlighting the need for more research on this condition.
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center.
Dermatol Pract Concept
July 2023
Department of Dermatology, University of Kırıkkale, Kırıkkale, Turkey.
Article Synopsis
- Telogen effluvium (TE) leads to significant hair shedding and its relation to vitamin and mineral deficiencies remains debated among researchers.
- This study analyzed data from 973 TE patients to assess deficiencies in vitamins and minerals, alongside their impact on anagen hair ratios using advanced phototrichogram technology.
- Results showed that while hemoglobin (HGB) levels positively correlated with hair growth ratios in women, other deficiencies, including ferritin and vitamins B12, D, and zinc, did not show significant links, suggesting HGB measurement can be a cost-effective initial test for TE management.
Pressure alopecias: A review.
J Am Acad Dermatol
January 2024
Trichology Clinic, Department of Dermatology, Hospital General "Dr. Manuel Gea González," Mexico City, Mexico. Electronic address:
Article Synopsis
- Pressure-induced alopecias (PAs) are a rare hair loss condition triggered by restricted blood flow to the scalp due to external pressure, occurring in two types: type 1 from prolonged pressure (such as during surgeries) and type 2 from cosmetic procedures involving injectables.
- Type 2 PA is becoming more common and can be confused with vascular occlusion-induced alopecia, highlighting the need for accurate diagnosis through clinical evaluation and potential use of trichoscopy.
- While hair loss can be evident, the condition is often self-limiting, with most cases seeing hair regrowth; treatment is generally unnecessary, but prognosis varies based on the extent of ischemia and response to timely interventions
Commonly prescribed medications associated with alopecia.
J Am Acad Dermatol
June 2023
Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Dermatology Service, US Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, Colorado. Electronic address:
Article Synopsis
- The study examines the relationship between commonly prescribed medications and alopecia (hair loss), focusing on those with strong evidence of association.
- Researchers identified 192 unique drugs, finding 13 with robust evidence linking them to alopecia, including medications like adalimumab and docetaxel.
- Limitations of the study include a focus on English-language articles and a possible bias towards more expensive drugs based on sales data rather than prescription volume.
Azathioprine Induced Anagen Effluvium- An Uncommon Adverse Effect of a Commonly Used Drug.
Indian J Dermatol
January 2022
Department of Dermatology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India E-mail:
Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
Regen Ther
December 2022
Department of Plastic and Reconstructive Surgery, School of Medicine, Fujita Health University, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan.
Article Synopsis
- Hair loss, or alopecia, has various psychosocial impacts and medical concerns, creating a significant economic burden for both individuals and society.
- Traditional medical treatments for alopecia have limitations, prompting research into newer regenerative therapies like mesenchymal stem cell (MSC) implantation and platelet-rich plasma treatments.
- The review explores existing studies from multiple medical databases to summarize promising regenerative treatments and discusses potential enhancements and innovative strategies for better clinical application in the future.
Hair Loss and Telogen Effluvium Related to COVID-19: The Potential Implication of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma as Regenerative Strategies.
Int J Mol Sci
August 2022
Plastic and Reconstructive Surgery, Department of Surgical Science, "Tor Vergata" University, 00133 Rome, Italy.
Article Synopsis
- The spread of SARS-CoV-2 has led to an increase in hair loss (HL) and telogen effluvium (TE) among COVID-19 patients, prompting a review of existing literature on the subject.
- The review highlights potential factors contributing to HL and TE, including psychological stress, systemic inflammation, and oxidative stress, which impact the normal function of hair-related proteins.
- Limited existing studies on treatments like Platelet-Rich Plasma (PRP) exist, indicating a need for more controlled trials to assess their effectiveness in addressing hair loss in COVID-19 patients.
Azathioprine-Induced Anagen Effluvium with Myelosuppression.
Skinmed
July 2022
Department of Dermatology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Article Synopsis
- Anagen effluvium and myelosuppression are uncommon side effects of the medication azathioprine.
- Hair loss from azathioprine occurs more often in transplant patients compared to those who aren't undergoing transplantation.
- The report discusses three patients who experienced hair loss and bone marrow suppression after being treated with azathioprine for skin conditions.
Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium.
J Eur Acad Dermatol Venereol
November 2022
Departamento de Dermatologia da FMB-Unesp, Botucatu, Brazil.
Azathioprine-Induced Marrow Suppression in Dermatology Patients - Analysis of 18 Patients.
Indian J Dermatol
January 2022
Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India.
Article Synopsis
- Azathioprine is an immunosuppressant used for various dermatological disorders but can cause serious marrow suppression, particularly affecting blood cell production.
- A study analyzed 18 patients (average age 25.88, mostly female) who experienced marrow suppression while on azathioprine, showing issues like leukopenia, thrombocytopenia, and low hemoglobin levels.
- Symptoms such as hair loss and oral ulcers appeared as early warning signs of marrow suppression, which generally resolved within a month after discontinuing the drug.
Article Synopsis
- - This study focuses on comparing the dermoscopic features of female androgenetic alopecia (FAGA) and telogen effluvium (TE) to healthy controls, emphasizing the differences in how hair loss appears microscopically.
- - A total of 124 female patients were observed, revealing significant differences in hair characteristics like hair diameter diversity and the prevalence of vellus hairs between FAGA, TE, and healthy controls.
- - The findings suggest that recognizing specific dermoscopic traits, such as the number of thin hairs and the presence of discoloration, can aid in the early diagnosis of FAGA and TE.
Management of hair loss after severe acute respiratory syndrome coronavirus 2 infection: Insight into the pathophysiology with implication for better management.
J Dermatol
October 2022
Clinical Development, Research and Development Headquarters Self-Medication, Taisho Pharmaceutical Co.Ltd, Tokyo, Japan.
Article Synopsis
- COVID-19, caused by SARS-CoV-2, has various lingering health effects post-recovery, including hair loss, which significantly impacts mental health and social life.
- * A narrative review analyzed 28 articles on hair loss related to COVID-19, identifying conditions like telogen effluvium and androgenetic alopecia as potential causes, with telogen effluvium being most common.
- * Treatment options, particularly topical minoxidil, show promise for alleviating hair loss symptoms, but further research is necessary to validate these findings.