1 results match your criteria: "An-Institute of RWTH[Affiliation]"
Impact of Latanoprost Antiglaucoma Eyedrops and Their Excipients on Toxicity and Healing Characteristics in the Ex Vivo Eye Irritation Test System.
Ophthalmol Ther
October 2023
Aachen Centre of Technology Transfer in Ophthalmology (ACTO E.V.), An-Institute of RWTH, Aachen, Germany.
Introduction: Corneal epithelial toxicity and delayed healing process have already been attributed to preservatives or some excipients. We study the effects of galenic components in antiglaucoma drugs such as benzalkonium chloride (BAC) or surfactants like macrogolglycerol hydroxystearate 40 (MGHS 40) on corneal toxicity in an ex vivo system mimicking chronic use.
Methods: Latanoprost-containing eyedrops are available with and without preservatives on the market.