1 results match your criteria: "Amsterdam. Zuiderzee Hospital[Affiliation]"
Patterns of resistance associated with integrons, the extended-spectrum beta-lactamase SHV-5 gene, and a multidrug efflux pump of Klebsiella pneumoniae causing a nosocomial outbreak.
J Clin Microbiol
March 2003
Municipal Public Health Laboratory, Amsterdam. Zuiderzee Hospital, Lelystad, The Netherlands.
Article Synopsis
- A nosocomial outbreak of multiresistant Klebsiella pneumoniae was investigated, revealing varied resistance patterns among patients and a need for improved screening methods.
- Genetic strain typing via pulsed-field gel electrophoresis confirmed the clonality of outbreak strains and identified at least one missed patient due to inadequate ESBL screening.
- The presence of the SHV-5 ESBL gene was found in almost all outbreak strains, and correlations between ciprofloxacin and cefoxitin MICs suggested that low-level expression of ESBL genes could evade detection, indicating the need for better screening criteria.