4 results match your criteria: "Amrita Institute Medical Sciences[Affiliation]"

Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians.

J Am Coll Cardiol

August 2020

Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

Background: Genome-wide polygenic scores (GPS) integrate information from many common DNA variants into a single number. Because rates of coronary artery disease (CAD) are substantially higher among South Asians, a GPS to identify high-risk individuals may be particularly useful in this population.

Objectives: This analysis used summary statistics from a prior genome-wide association study to derive a new GPS for South Asians.

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Near-infrared measurements of brain oxygenation in stroke.

Neurophotonics

July 2016

University of Calgary, Department of Radiology, Foothills Medical Centre, Room 812, North Tower, 1403-29th Street NW Calgary, Alberta T2N 2T9, Canada; University of Calgary, Hotchkiss Brain Institute, Health Research Innovation Centre, Room 1A10, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada; University of Calgary, Experimental Imaging Center, TRW building, Basement level P2, Foothills Medical Centre, 1403-29th Street NW Calgary, Alberta T2N 2T9, Canada.

We investigated the feasibility of using frequency-domain near-infrared spectroscopy (fdNIRS) to study brain oxygenation in the first few hours of stroke onset. The OxiplexTS(®) fdNIRS system was used in this study. Using a standard probing protocol based on surface landmarks, we measured brain tHb and [Formula: see text] in healthy volunteers, cadavers, and acute stroke patients within 9 h of stroke onset and 3 days later.

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