Outcome and Determining Characteristics of ICU Patients with Acute Kidney Injury in a Low-Income Country, a Multicenter Experience.

Background: Acute kidney injury (AKI) is a disease that affects millions of people globally making it a major public health concern. It is defined as an abrupt decrease in kidney function that occurs within ours affecting both the structure and functionality of the kidneys.The outcome of AKI and the determinants in Nigeria are largely unknown.

Morphological Patterns of Spinal Degeneration and Trauma in a Nigerian Population: a Retrospective Radio-Anatomic Study.

Background: Understanding the morphological patterns of degenerative and traumatic spinal conditions is essential for precise diagnosis and management plans. This study evaluates the sequence of structural changes in degenerative spinal disorder patients' disco-vertebral unit and the traumatic spinal injury patterns in a northwestern Nigerian population.

Methods: A hospital-based retrospective study reviewed radiologic images of 307 patients with spinal degeneration (n=269) and trauma (n=38) at two tertiary hospitals in Northwest Nigeria.

Rheumatic Heart Disease Burden in Africa and the Need to Build Robust Infrastructure.

Rheumatic heart disease (RHD) is an important public health problem in Africa. Mapping the epidemiology of RHD involves elucidating its geographic distribution, temporal trends, and demographic characteristics. The prevalence of RHD in Africa varies widely, with estimates ranging from 2.

Exploring the impact of interferon-gamma single nucleotide polymorphisms on HTLV-1 infection: Unraveling genetic influences in viral pathogenesis.

Human T-lymphotropic virus-1 (HTLV-1) induces neoplastic adult T-cell leukemia/lymphoma (ATLL) and neurological HTLV-1 associated myelopathy (HAM) in approximately 3 %-5 % of infected individuals. The precise factors that facilitate disease manifestation are still unknown; interaction between the virus and the host's immune response is key. Cytokines regulates physiological activities and their dysregulation may initiate the pathogenesis of various malignant and infectious diseases.

Adapted Counseling Care Model for Management of Female Sexual Dysfunction Among Women Living With and Without HIV.

Background And Objective: Sexual health research among women living with human immunodeficiency virus (HIV) has focused mainly on sexual practices and risk behaviors, with little consideration for treating sexual dysfunction and improving sexual satisfaction. The aim of this pilot study was to assess the effectiveness of an adaptive counseling care model in the management of female sexual dysfunction (FSD) among women living with HIV and without HIV in northern Nigeria.

Methods: This was a prospective cohort study of 200 women with HIV and a matched comparison arm of 200 women without HIV.

Sinonasal Leiomyoma: A Case Report and a Review of the Literature.

Sinonasal leiomyoma is an exceptionally rare neoplasm arising from smooth muscle cells within the sinonasal tract. This abstract presents a case study of a 43-year-old male patient diagnosed with sinonasal leiomyoma, a distinctive and challenging entity in otolaryngology. The patient presented with a complex clinical history, including a 2-year interval between initial evaluation and definitive diagnosis.

Repair of Cleft Palate in Adult Patients; Impact of Speech Therapy Following Surgical Intervention in Africa.

Cleft lip and palate anomalies constitute both aesthetic and functional impairments for affected individuals. While an individual with an unrepaired cleft palate may adjust somewhat to the associated feeding challenges as he or she gets older, the consequent speech impairment is amenable primarily to surgery. It is pertinent to assess how well speech function is restored in individuals with cleft after surgical repairs.

Prevalence and trends of pregnancy-related acute kidney injury in sub-Saharan Africa: a systematic review and meta-analysis.

Background: Pregnancy-Related Acute Kidney Injury (PRAKI) is an important contributor to maternal-fetal morbidity and mortality. The burden of PRAKI in sub-Saharan Africa is not well documented. We conducted a systematic literature review and meta-analysis to estimate the prevalence of PRAKI in sub-Saharan Africa.

Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method.

Purpose: To generate consensus and provide expert clinical practice statements for the management of adult sepsis in resource-limited settings.

Methods: An international multidisciplinary Steering Committee with expertise in sepsis management and including a Delphi methodologist was convened by the Asia Pacific Sepsis Alliance (APSA). The committee selected an international panel of clinicians and researchers with expertise in sepsis management.

HPV vaccine hesitancy among parents and caregivers of adolescents in Northern Nigeria.

Background: The recent introduction of the HPV vaccine into Nigeria's routine immunization schedule has brought parental vaccine hesitancy to the forefront. This cross-sectional study, conducted in Kano State, a region with historically low immunization rates, is crucial in assessing the level of parental hesitancy and uncovering its determinants, potentially informing future public health policies.

Methods: The participants were a representative sample of parents or caregivers of children aged 9-14 years ( = 1071) in Kano State and were selected via a multi-stage sampling method.

Pure tone and speech audiometry of presbyacusis in a tertiary hospital in Kaduna, Nigeria: a cross-sectional study.

Introduction: presbyacusis is age-related hearing loss, manifesting as a bilateral symmetrical sensorineural hearing loss of adult-onset. It has different audiometric configurations and is associated with a decline in speech discrimination sensitivity. The objectives of the study were to determine the degree of hearing loss; types of presbyacusis; and speech discrimination score (SDS) of presbyacusics and to compare the SDS in different types of presbyacusis in patients seen at a tertiary hospital in Kaduna, Nigeria.

Survey of anatomic and clinical pathology services and infrastructure in Nigeria.

Objectives: The paucity of data regarding the availability and extent of diagnostic medical services across sub-Saharan Africa hinders appropriate allocation of resources to improve health care in these regions. We assessed anatomic pathology (AP) and clinical pathology (CP) services in Nigeria, one of the most populous and fastest-growing countries in the world.

Methods: Two individual surveys (AP focused and CP focused) were developed by subject matter experts and administered to individuals involved in pathology and laboratory medicine diagnostic services at hospitals and laboratories across Nigeria between June and August 2022 using the American Society for Clinical Pathology email listserv.

Plantar sensory stimulation and its impact on gait and lower limb motor function in individuals with stroke: A systematic review and meta-analysis.

Background: Stroke frequently leads to motor impairments, with almost half of the affected individuals experiencing diminished sensation, impacting their overall quality of life and autonomy. Rehabilitation efforts, however, often overlook somatosensory functions of the lower limbs. While plantar sensory stimulation activates receptors in the foot sole, its precise impact on the motor functions and gait of individuals with stroke is yet to be ascertained.

Assessment of patients' satisfaction with healthcare services provided under the Nigeria national health insurance authority.

Background: The Nigeria National Health Insurance Authority (NHIA) is the official Social Health Insurance Agency of the Federal Government established to provide quality healthcare services to Nigerians at affordable cost, sufficient to address catastrophic health expenditures. One key indicator of quality healthcare services is patient satisfaction. This National Survey aimed to assess enrollees' satisfaction with healthcare services under this organization.

Prevalence and Factors Associated with Zero-Dose Children amongst Nomadic and Non-Nomadic Fulani in Yobe State, North-East Nigeria.

Background: Immunization is a very cost-effective and readily available intervention capable of preventing Vaccines Preventable Diseases (VPDs). This study aimed to identify and compare the prevalence and factors associated with zero-dose immunization status among children of nomadic and non-nomadic Fulani in Yobe State, North-East Nigeria.

Methodology: A comparative cross-sectional design was used to study 348 nomadic, and 345 non-nomadic under-five children, selected using a multi-staged sampling technique.

Left Ventricular Mass, Geometric Patterns, and Diastolic Myocardial Performance in Children with Obstructive Sleep Apnea.

Background: Obstructive sleep apnea (OSA), characterized by recurrent partial or complete upper airway obstructions during sleep, is an established risk factor for cardiovascular diseases in children. This study aims to determine the prevalence of left ventricular hypertrophy (LVH), abnormal left ventricular (LV) geometric patterns, and diastolic dysfunction in children with OSA and compare them with healthy controls.

Materials And Methods: This was a cross-sectional comparative study conducted on 75 eligible children with OSA aged 2-14 years and 75 age- and sex-matched healthy children.

Sustainable menstrual solutions: a scoping review of novel eco-friendly materials for reusable menstrual pads.

Background: Reusable menstrual pads (RMPs) offer a sustainable alternative, but the effectiveness and properties of novel eco-friendly materials for RMPs remain unclear. The objective of this scoping review is to identify novel eco-friendly materials used for RMPs.

Methods: This review adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews.

Correlates of Food Contamination by Heavy Metals in Northwest Nigeria.

Background: The increasing cases of chronic kidney disease is a global public health concern. The potential link between consumption of food contaminated with heavy metals and development of end stage renal disease is becoming an emerging challenge. This study aimed to identify heavy metal contaminants in food and environmental risk factors for development of chronic kidney disease in Nigeria.

A comparative study of food safety knowledge among mobile food vendors and canteen food handlers in markets in Kano Metropolis, Northwest Nigeria.

Introduction: foodborne diseases are an emerging public health challenge due to the global increase in vended food. This study aimed to compare food safety knowledge among mobile and canteen food handlers in Kano metropolis.

Methods: a comparative cross-sectional design was used to study 310 mobile food vendors and 310 canteen food handlers selected using a multi-stage sampling technique.

PATHWAYS TO CARE AMONG PATIENTS WITH MENTAL ILLNESS AT USMANU DANFODIYO UNIVERSITY TEACHING HOSPITAL, SOKOTO, NIGERIA.

Background: The first line of care is a paramount stage in the management of the mentally ill persons. In Nigeria, traditional and faith-based healers compete with medical professionals in providing care.

Aim: Pathway to care among patients with Mental Illness at Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.

DEPRESSION AS A PREDICTOR OF OPIOID USE DISORDER IN SICKLE CELL DISEASE PATIENTS.

Background: Sickle cell disease (SCD) is highly prevalent in Africa, especially in Nigeria, the most populous country, and is associated with a high mortality rate. Depression, common among individuals with SCD, correlates with increased pain intensity and opioid misuse, leading to poorer outcomes and diminished quality of life in these patients.

Aim: To determine whether major depressive disorder is a predictor of opioid use disorder among patients with sickle cell disease.