1,765 results match your criteria: "Amiens University[Affiliation]"

Article Synopsis
  • - Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent among obese individuals and shows differences between sexes. A study sought to create a noninvasive blood test using mid-infrared (MIR) metabolic fingerprinting to diagnose metabolic dysfunction-associated steatohepatitis (MASH) in those with severe obesity.
  • - The study involved 382 patients undergoing bariatric surgery, with liver biopsies assessed to establish a scoring algorithm based on MIR spectroscopy. In women, MASH was diagnosed in 14.3% of cases, showing high sensitivity (86%) and specificity (81%) for correctly identifying the condition.
  • - For men, the test's performance was notably less effective, with a MASH diagnosis
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Is an excessively high posterior tibial slope a predisposition to knee injuries in children? Systematic review of the literature.

Orthop Traumatol Surg Res

October 2024

Service d'Orthopédie et Traumatologie Pédiatrique, CHU Amiens-Picardie, 80054, Amiens Cedex 1, France; GRECO (Groupement de Recherche et d'Etudes en Chirurgie Robotisée), Amiens University Hospital and Jules Verne University of Picardie, Amiens, France.

Article Synopsis
  • * Out of 294 identified studies, 11 were included, which highlighted a significant correlation between elevated PTS and ACL injuries, showing an increase in PTS by 2.1° to 4.3° in affected patients compared to healthy individuals.
  • * The findings suggest that a high PTS may be linked to an increased risk of knee pathologies in children, necessitating careful consideration when assessing young athletes with ACL injuries.
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Article Synopsis
  • The incidence of inflammatory bowel disease (IBD) in Northern France was studied over a 30-year period, revealing 22,879 new cases, with Crohn's disease (CD) and ulcerative colitis (UC) making up the majority.
  • The incidence rates for both CD and UC increased significantly over the years, particularly in children and young adults, indicating a rising trend in these demographics.
  • The findings suggest ongoing environmental factors contributing to the increasing prevalence of IBD, especially among women with UC, with projections indicating that nearly 0.6% of the population will have IBD by 2030.
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Article Synopsis
  • The study investigates the presence of human papillomavirus (HPV) in the semen of men seeking infertility treatment at Amiens University Hospital from May to October 2021, involving 461 participants who provided informed consent.
  • Semen samples were analyzed for HPV using PCR, revealing that 22.3% of men carried HPV, with high-oncogenic-risk types being the most common (57.6%).
  • The analysis found significant associations between HPV carriage and factors like abnormal sperm quality, type of infertility, presence of varicocele, and certain testicular conditions, indicating that HPV may contribute to infertility risks.
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Individuals with neurodevelopmental disorders (NDDs) are more susceptible to developing severe or resistant mood disorders. However, they often face challenges in accessing specific treatments. To understand the barriers to treatment in this group, we conducted a secondary analysis of a multicenter observational study on 305 adolescents referred to specialized care (mean age 14.

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Background: The anti-neutrophil cytoplasmic antibody (ANCA) renal risk score (ARRS) for predicting renal survival in ANCA-associated vasculitis (AAV) had not previously been validated in adults over 65 years of age and presenting impairments associated with an aging kidney, a high cardiovascular comorbidity burden and prevalent microscopic polyangiitis.

Methods: We retrospectively studied a cohort of 192 patients over 65 years of age [median (interquartile range) age: 73 (68-78) years], including 17.2% with renal-limited vasculitis, 49.

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Cerebral air embolism following a hemodialysis session successfully treated with hyperbaric oxygen: a case report.

Ther Adv Neurol Disord

October 2024

Department of Nephrology, Dialysis, and Transplantation, Amiens University Hospital, University of Picardie Jules Verne, F-80054 Amiens, France.

Article Synopsis
  • A 39-year-old woman developed cerebral air embolism (CAE) during hemodialysis due to a faulty central venous catheter, which can be a rare but serious complication, especially affecting the brain.
  • She initially presented with a seizure and was monitored in the Intensive Care Unit, later experiencing worsening symptoms such as aphasia and hemiplegia before being treated with hyperbaric oxygen therapy (HBOT).
  • After three sessions of HBOT, she fully recovered, with post-treatment seizures linked to hyperoxia, underscoring the need for vigilant monitoring and immediate treatment in lung transplant patients undergoing hemodialysis.
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Article Synopsis
  • The study focuses on improving the distinction between brain metastasis progression (BMP) and brain radionecrosis (BRN) using advanced F-FDOPA PET/CT technology.
  • A new method involves a quick 3-second sampling during a 4-minute acquisition, applied to 15 patients with 19 metastases, to analyze activity ratios in brain lesions.
  • Results showed the VOImax/CLmean ratio had high diagnostic accuracy (94.7%) and successfully differentiated BMP from BRN, suggesting the new approach is more efficient than traditional methods.
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Background: Virological failure (VF) among children remains concerning, with high risks of HIV drug resistance (HIVDR) emergence and increased disease progression. Therefore, monitoring of viral non-suppression and emerging HIVDR is crucial, especially in the frame of sociopolitical unrest.

Objective: The study sought to determine the prevalence of VF and evaluate the acquired HIVDR and viral genetic diversity among children in the Northwest region of Cameroon during the ongoing sociopolitical crisis.

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Article Synopsis
  • * Despite advancements in understanding and treating aortic stenosis, there are still significant gaps in knowledge about its causes, severity assessment, and treatment strategies.
  • * The review, from the Heart Valve Council of the French Society of Cardiology, highlights these gaps and suggests areas for future research to enhance patient outcomes.
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Dupilumab in atopic-dermatitis-like eczema associated with inborn errors of immunity: A nationwide study.

J Am Acad Dermatol

January 2025

Department of Dermatology, Reference Center for Genodermatoses (MAGEC), Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris Cité University, Paris, France; Imagine Institute, INSERM UMR1163, Paris Cité University, Paris, France. Electronic address:

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Abstracts accepted for the 2021-2023 French Orthopaedic and Traumatology Society meetings: Proportion of women submitters.

Orthop Traumatol Surg Res

September 2024

University Institute for Spine Surgery, Armand Trousseau Hospital, Sorbonne Université, 26 avenue du Dr Netter, 75012 Paris, France.

Background: Women are underrepresented in orthopaedic and trauma surgery worldwide, with proportions of 4%-17% across countries and 9.1% in France. The annual meeting of the French Society for Orthopaedic and Trauma Surgery (SOFCOT) provides opportunities for quantifying the representation of women, which has not yet been accurately evaluated.

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Article Synopsis
  • Patients with inflammatory bowel disease (IBD), specifically children with Crohn's disease (CD) and ulcerative colitis (UC), have a higher risk of thromboembolic events (TE), but more information is needed regarding the incidence and risk factors for better preventative care.
  • The study followed 1,344 pediatric patients from 1988 to 2013, finding very few instances of arterial (ATE) and venous thromboembolic events (VTE) during the follow-up period, with VTE being more frequent in specific circumstances.
  • Overall, while the risk of TE in this population is low, it was significantly linked to periods of active disease, post-surgery conditions, and hospitalization, while treatment with
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Article Synopsis
  • Advanced systemic mastocytosis (AdvSM) is a complex condition linked to poor outcomes, and while midostaurin is the first approved treatment, its long-lasting effectiveness is limited.
  • Various prognostic scoring systems like MARS, IPSM, and GPSM have been developed to assess patients' outcomes, but it's essential to tailor these scores to specific AdvSM subtypes for better accuracy.
  • A study of patients treated with midostaurin revealed that MARS and AdvSM subtype significantly predict overall survival, identifying five distinct patient subgroups with varying median survival times, highlighting the need for personalized management strategies.
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Article Synopsis
  • * Researchers analyzed data from 88 patients with 96 strictures over nearly 30 years, noting that a significant percentage of the strictures were nonpassable and symptomatic, leading to surgical interventions for many.
  • * Ultimately, 8% of patients were diagnosed with cancer at the stricture site, often at the same time as the stricture; however, no patients were reported to have malignant strictures after one year of follow-up.
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An accurate diagnosis of lower limb deep vein thrombosis (DVT) recurrence is mandatory. The diagnosis is difficult and has not been well investigated. Our objective was to define the role of clinical probability assessment, D-dimer assay, venous ultrasound and other imaging methods in the diagnosis of this condition based on a review of published data.

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Purpose: To evaluate the accuracy of ultra-low dose (ULD) chest computed tomography (CT), with a radiation exposure equivalent to a 2-view chest x-ray, for pulmonary nodule detection using deep learning image reconstruction (DLIR).

Material And Methods: This prospective cross-sectional study included 60 patients referred to our institution for assessment or follow-up of solid pulmonary nodules. All patients underwent low-dose (LD) and ULD chest CT within the same examination session.

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Fluid responsiveness in acute respiratory distress syndrome patients: a post hoc analysis of the HEMOPRED study.

Intensive Care Med

November 2024

Medical and Surgical intensive care unit, University Hospital Ambroise Paré, GHU Paris-Saclay, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, France.

Purpose: Optimal fluid management in patients with acute respiratory distress syndrome (ARDS) is challenging due to risks associated with both circulatory failure and fluid overload. The performance of dynamic indices to predict fluid responsiveness (FR) in ARDS patients is uncertain.

Methods: This post hoc analysis of the HEMOPRED study compared the performance of dynamic indices in mechanically ventilated patients with shock, with and without ARDS, to predict FR, defined as an increase in aortic velocity time integral (VTI)  > 10% after passive leg raising (PLR).

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Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis.

Haematologica

January 2025

Université Paris Cité, INSERM UMR-S1151, CNRS UMR-S8253, Institut Necker Enfants Malades, F-75015 Paris, France; Hôpital Necker Enfants-Malades, Laboratoire d'Onco-Hématologie, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris.

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Smoking and diabetes.

Ann Endocrinol (Paris)

December 2024

Champagne-Ardenne University, UMR CNRS 7369 MEDyC & Cardio-Thoracic Department, Reims University Hospital, Reims, France.

Article Synopsis
  • Smoking contributes to insulin resistance and negatively impacts beta-cell function, both of which are poorly understood factors linked to the development of type-2 diabetes.
  • Active smoking harms glycemic control in both type-1 and type-2 diabetics, increasing all-cause mortality and exacerbating diabetes-related complications, while its effects on specific complications are still debated.
  • There’s a lack of comprehensive data on smoking cessation strategies tailored for diabetic patients, highlighting the need for diabetes specialists to actively engage in supporting smoking cessation efforts.
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The role of SEEG in the presurgical decision-making process in MRI-normal mesial temporal lobe epilepsy.

Rev Neurol (Paris)

December 2024

Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Lyon 1 University, Lyon, France; Lyon Neuroscience Research Center, Inserm U1028, CNRS UMR5292, Lyon 1 University, Lyon, France.

Article Synopsis
  • In patients with mesial temporal lobe epilepsy (mTLE) who have normal MRI results, there is debate about whether to perform anterior temporal lobectomy while sparing the hippocampus due to potential memory loss risks.
  • A study examined 17 patients with normal MRIs and EEG data that indicated unilateral seizure activity, categorizing them into two groups based on the timing of hippocampal involvement during seizures.
  • The results showed no significant difference in post-operative seizure and neuropsychological outcomes regardless of whether the hippocampus was removed during surgery, suggesting that SEEG should be part of the surgical planning for these patients.
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Background And Aims: Severe tricuspid regurgitation is associated with increased mortality rates, but benefit of its correction and ideal timing are not clearly determined. This study aimed to identify patient subsets who might benefit from the surgery.

Methods: In TRIGISTRY, an international cohort study of consecutive patients with severe isolated functional tricuspid regurgitation (33 centres, 10 countries), survival rates up to 10 years were compared between patients who underwent isolated tricuspid valve surgery (repair or replacement) and those conservatively managed, overall and according to TRI-SCORE category (low: ≤3, intermediate: 4-5, and high: ≥6).

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Article Synopsis
  • * Conducted across 40 hospitals in France, the trial involved 2,222 patients who were randomly assigned to either keep using RASIs until surgery or stop them 48 hours prior.
  • * The results showed no significant difference in all-cause mortality or major complications within 28 days after surgery between the two groups, suggesting that either strategy can be safely applied.
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