23,098 results match your criteria: "Amherst; †Baystate Franklin Medical Center[Affiliation]"
Int J Nurs Health Care Res (Lisle)
October 2024
Helfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
Introduction: Binge Eating Disorder (BED) has high lifetime prevalence rates, low treatment success rates, and high rates of treatment dissatisfaction, early discontinuation of care, and recurrence. Complementary and integrative health (CIH) interventions (non-mainstream practices used with conventional approaches for whole-person treatment) hold potential to overcome many treatment barriers and improve BED treatment outcomes. Some CIH interventions have empirical support for use in eating disorders.
View Article and Find Full Text PDFJ Pediatric Infect Dis Soc
January 2025
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH Bethesda, MD, USA.
Background: Vertical HIV-1 transmission despite antiretroviral therapy may be mitigated by use of long-acting, broadly neutralizing, monoclonal antibodies (bNAb) such as VRC07523LS. The present study was designed to determine the safety and pharmacokinetics of VRC07523LS.
Methods: VRC07523LS, 80 mg/dose, was administered subcutaneously after birth to non-breastfed (Cohort 1; N=11, enrolled in USA) and breastfed (Cohort 2; N=11, enrolled in South Africa and Zimbabwe) infants exposed to HIV-1.
Nat Commun
January 2025
Morphing Matter Lab, Human-Computer Interaction Institute, Carnegie Mellon University, Pittsburgh, PA, USA.
Compliant mechanisms with reconfigurable degrees of freedom are gaining attention in the development of kinesthetic haptic devices, robotic systems, and mechanical metamaterials. However, available devices exhibit limited programmability and form-customizability, restricting their versatility. To address this gap, we propose a metastructure concept featuring reconfigurable motional freedom and tunable stiffness, adaptable to various form factors and applications.
View Article and Find Full Text PDFJ Phys Condens Matter
January 2025
School of Physical Sciences, NISER, Jatni, Bhubaneswar, 752050, INDIA.
We study topological charge pumping (TCP) in the Rice-Mele (RM) model with irreciprocal hopping. The non-Hermiticity gives rise to interesting pumping physics, owing to the presence of skin effect and exceptional points. In the static one-dimensional (1D) RM model, we find two independent tuning knobs that can drive the topological transition, namely, non-Hermitian parameter $\gamma$ and system size $N$.
View Article and Find Full Text PDFTrauma Violence Abuse
January 2025
Department of Psychology, University of Wisconsin-Madison, Madison, WI, USA.
Although sexual violence (SV) has been hypothesized to increase shame, the relationship between SV and shame has not been quantified. Addressing this gap is essential for developing targeted interventions for survivors, as shame is a transdiagnostic risk factor for numerous forms of psychopathology and a barrier to service-seeking. This meta-analysis first examines whether individuals exposed to SV demonstrate higher shame than individuals who reported no SV exposure.
View Article and Find Full Text PDFJ Appl Psychol
January 2025
Advanced Research Institute of Business, School of Economics and Management, Tongji University.
Leaders, often perceived as possessing exceptional confidence and competence, are not immune to feelings of self-doubt. Leader impostorism describes the experience that one's attributes, experiences, skills, and abilities fall short of the standards expected in the leadership role, resulting in a sense of deception in fulfilling leadership responsibilities. While existing research has examined the antecedents and individual outcomes of leader impostorism, its implications for leaders' treatment of subordinates remain largely unexplored.
View Article and Find Full Text PDFScience
January 2025
The reviewer is at the School of Science and Mathematics, Hampshire College, Amherst, MA, USA.
A data-driven portrait of racism exposes the persistent reality of racial biases.
View Article and Find Full Text PDFEpidemics
December 2024
Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, United States.
Over the last ten years, the US Centers for Disease Control and Prevention (CDC) has organized an annual influenza forecasting challenge with the motivation that accurate probabilistic forecasts could improve situational awareness and yield more effective public health actions. Starting with the 2021/22 influenza season, the forecasting targets for this challenge have been based on hospital admissions reported in the CDC's National Healthcare Safety Network (NHSN) surveillance system. Reporting of influenza hospital admissions through NHSN began within the last few years, and as such only a limited amount of historical data are available for this target signal.
View Article and Find Full Text PDFDis Mon
January 2025
NYU Grossman School of Medicine, Department of Population Health, New York, NY, USA.
3,4-methylenedioxymethamphetamine (MDMA; commonly referred to as "ecstasy" or "molly") is a substituted amphetamine drug that is used recreationally for its acute psychoactive effects, including euphoria and increased energy, as well as prosocial effects such as increased empathy and feelings of closeness with others. Acute adverse effects can include hyperthermia, dehydration, bruxism, and diaphoresis. Post-intoxication phenomena may include insomnia, anhedonia, anxiety, depression, and memory impairment, which can persist for days following drug cessation.
View Article and Find Full Text PDFN Engl J Med
January 2025
From the Office of Diversity Inclusion and Community Partnership (J.Y.R.), the Department of Medicine (J.Y.R.), and the Department of Global Health and Social Medicine (D.S.J.), Harvard Medical School; the Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health (J.Y.R.); the Department of Medicine, Section of General Internal Medicine, Boston University Chobanian and Avedisian School of Medicine (C.G.S.); and the GenderCare Center, Boston Medical Center (C.G.S.) - all in Boston; the Department of the History of Science (B.M., J.M., A.H., S.S.R.), and the Committee on Degrees in Studies of Women, Gender, and Sexuality (S.S.R.), Harvard University, Cambridge, MA; Board of Directors, Tegan and Sara Foundation, Santa Monica, CA. (J.H.); and the Departments of History and of Sexuality, Women's, and Gender Studies, Amherst College, Amherst, MA (J.M.).
J Acquir Immune Defic Syndr
November 2024
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA.
Background: Limited data exist on bictegravir pharmacokinetics in pregnancy among persons with HIV (PWH) and infant washout.
Setting: Nonrandomized, open-label, multi-center phase-IV prospective study of bictegravir pharmacokinetics and safety in pregnant PWH and their infants.
Methods: Steady-state 24-hour pharmacokinetic sampling of oral bictegravir 50 mg once daily (a component of fixed-dose combination bictegravir/emtricitabine/tenofovir alafenamide) during the 2nd and 3rd trimesters and postpartum was performed.
J Occup Environ Hyg
January 2025
Finance Department, University of Texas at Austin, Austin, Texas.
The present paper provides an assessment of how the scientific and national policy achievements/goals of Hermann J. Muller were impacted by his ethics and provides several documented episodes in which Muller acted unethically to promote his personal gain-at the expense of others-within the scientific community. Muller manipulated the scientific community in self-serving ways to suppress perspectives that challenged his own views on radiation-induced gene mutation, and hereditary and cancer risk assessment in ways that influenced his significant awards (e.
View Article and Find Full Text PDFCrit Rev Food Sci Nutr
January 2025
School of Food Science and Technology, Jiangnan University, Wuxi, China.
Traditionally, food packaging was used to extend the shelf life of food or to monitor its condition. Inspired by many biological structures found in nature, bio-inspired functional materials for bio-based food packaging have been shown to have significantly improved capabilities over traditional bio-based food packaging materials in various aspects and to attract consumers through novel freshness preservation features. This review synthesizes recent advances in bio-inspired bio-based food packaging materials that mimic the structure of natural organisms with specific functionalities, with examples of specific biomimetics in different enhancement areas.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Polymer Science and Engineering, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Direct translocation of RNA with secondary structures using single-molecule electrophoresis through protein nanopores shows significant fluctuations in the measured ionic current, in contrast to unstructured single-stranded RNA or DNA. We developed a multiscale model combining the oxRNA model for RNA with the 3-dimensional Poisson-Nernst-Planck formalism for electric fields within protein pores, aiming to map RNA conformations to ionic currents as RNA translocates through three protein nanopores: α-hemolysin, CsgG, and MspA. Our findings reveal three distinct stages of translocation (pseudoknot, melting, and molten globule) based on contact maps and current values.
View Article and Find Full Text PDFACS Med Chem Lett
January 2025
Laboratory of Organic and Medicinal Chemistry, Department of Chemistry, Malaviya National Institute of Technology, Jawaharlal Nehru Marg, Jaipur 302017, India.
A series of novel N-arylsulfonylated C-homoaporphine alkaloids were synthesized under microwave irradiation and evaluated for their antiplatelet and antimicrobial activities. Among the series, compounds , , , , , , , , and demonstrated highly potent (∼3-fold) platelet aggregation inhibitory activity than acetylsalicylic acid (IC = 21.34 μg/mL).
View Article and Find Full Text PDFJ Undergrad Neurosci Educ
December 2024
Department of Biology, Amherst College, Amherst, MA 01002.
Course-based undergraduate research experiences (CUREs) provide a variety of benefits to student learning outcomes. Here we describe an upper-level semester-long CURE that was implemented in Spring 2024 at Amherst College, a small liberal arts college, as part of the NEUR 313: Social Neuroendocrinology course. In the CURE students conducted behavioral and immunohistochemical assays in the fighting fish .
View Article and Find Full Text PDFRev Sci Instrum
January 2025
NASA Goddard Space Flight Center, Greenbelt, Maryland 20771, USA.
This work describes the design and implementation of optics for EXCLAIM, the EXperiment for Cryogenic Large-Aperture Intensity Mapping. EXCLAIM is a balloon-borne telescope that will measure integrated line emission from carbon monoxide at redshifts z < 1 and ionized carbon ([CII]) at redshifts z = 2.5 - 3.
View Article and Find Full Text PDFFront Psychol
December 2024
Digital Cognitive Dx, Philips, Eindhoven, Netherlands.
We evaluated a digital cognitive assessment platform, Philips IntelliSpace Cognition, in a case-control study of patients diagnosed with mild cognitive impairment (MCI) and cognitively normal (CN) older adults. Performance on individual neuropsychological tests, cognitive -scores, and Alzheimer's disease (AD)-specific composite scores was compared between the CN and MCI groups. These groups were matched for age, sex, and education.
View Article and Find Full Text PDFPNAS Nexus
January 2025
Department of Mathematics and Statistics, University of Massachusetts Amherst, Amherst, MA 01002, USA.
Every protein progresses through a natural lifecycle from birth to maturation to death; this process is coordinated by the protein homeostasis system. Environmental or physiological conditions trigger pathways that maintain the homeostasis of the proteome. An open question is how these pathways are modulated to respond to the many stresses that an organism encounters during its lifetime.
View Article and Find Full Text PDFSmall
January 2025
Polymer Science & Engineering Department, Conte Center for Polymer Research, University of Massachusetts, 120 Governors Drive, Amherst, MA, 01003, USA.
J Phys Condens Matter
January 2025
School of Physical Sciences, NISER, Jatni, Bhubaneswar, 752050, INDIA.
We study topological charge pumping (TCP) in the Rice-Mele (RM) model with irreciprocal hopping. The non-Hermiticity gives rise to interesting pumping physics, owing to the presence of skin effect and exceptional points. In the static one-dimensional (1D) RM model, we find two independent tuning knobs that can drive the topological transition, namely, non-Hermitian parameter $\gamma$ and system size $N$.
View Article and Find Full Text PDFAnnu Rev Food Sci Technol
January 2025
1Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; email:
Foodborne illnesses are a significant global public health challenge, with an estimated 600 million cases annually. Conventional food microbiology methods tend to be laborious and time consuming, pose difficulties in real-time utilization, and can display subpar accuracy or typing capabilities. With the recent advancements in third-generation sequencing and microbial omics, nanopore sequencing technology and its long-read sequencing capabilities have emerged as a promising platform.
View Article and Find Full Text PDFMatern Child Health J
January 2025
Faculty of Medicine, University of Parakou, Parakou, Benin.
Introduction: Globally, the prevalence of undernutrition is highest in the sub-Saharan African region with over a third of the world's stunted children residing in this region. Many studies have explored child nutrition in sub-Saharan Africa, but they often overlook the intricate nuances of maternal knowledge. We examined the association between maternal nutritional knowledge and childhood nutritional outcomes.
View Article and Find Full Text PDFJ Exp Psychol Learn Mem Cogn
December 2024
University of Massachusetts-Amherst, Department of Psychological and Brain Sciences.
Listeners can use both lexical context (i.e., lexical knowledge activated by the word itself) and lexical predictions based on the content of a preceding sentence to adjust their phonetic categories to speaker idiosyncrasies.
View Article and Find Full Text PDF