Changes of blood cholinesterase activities among pesticides-exposed agricultural workers in Iraq: A meta-analysis.

Numerous studies in Iraq have attempted to determine blood cholinesterase (ChE) activities with varying results in agricultural workers and veterinarians exposed to pesticides. This meta-analysis answers the specific inquiry of whether or not blood ChE activities decrease in agricultural workers exposed previously to pesticides. The meta-analysis included 14 records of blood ChE activities extracted from 12 studies after employing the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA).

The Potential Risk of Reduced Serum Cholinesterase Activity in COVID-19 Patients Suffering From Cytokine Storm.

Background and objective Several blood biochemical parameters are used to biomonitor coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Reduced serum cholinesterase (ChE) has been suggested to be a predictive indicator of the severity and outcome of COVID-19 infection. This study aimed to examine serum ChE activity in hospitalized and terminally ill COVID-19 patients with cytokine storm and evaluate the enzyme for the in vitro ChE-inhibitory activity of the organophosphate dichlorvos.

An Explicit Data-Driven Model for Estimation of Free and Absorbed Gas Volumes in Shale Gas Reservoirs.

Shale gas reservoir fluid flow is characterized by complex interactions between a number of variables, including stress sensitivity, matrix shrinkage, and critical desorption pressure. The behavior and productivity of shale gas reservoirs are significantly influenced by these variables. Therefore, in this study, an in-house finite element poro-elastic simulator was integrated with an in-house Fortran-coded artificial neural network model for accurate estimation of free and absorbed gas volumes in shale gas reservoirs, taking into account the combined effects of stress sensitivity, matrix shrinkage, and critical desorption pressure.

Antidotal Effects of the Antihistamine Diphenhydramine Against Cholinesterase Inhibitor Poisoning: A Meta-Analysis of Median Lethal Doses in Experimental Animals.

The H-antihistamine diphenhydramine antagonizes cholinesterase inhibitor poisoning in various animal species. One aspect of acute antidotal actions of diphenhydramine is increasing the median lethal doses (LD50) of toxicants. The objective of this meta-analysis was to assess the antidotal action of diphenhydramine against short-term toxicity (LD50) of cholinesterase inhibitors in experimental animals.

Explicit Data-Based Model for Predicting Oil-Based Mud Viscosity at Downhole Conditions.

One of the functions of drilling mud is to transport cuttings out of a drilled well. To fulfill this purpose, the mud must possess optimal viscous characteristics. The main goal of this study is to develop a model for estimating the plastic viscosity (PV) of oil-based muds (OBMs) at downhole conditions, especially when high-temperature, high-pressure wells are drilled.

Oxidative Stress-Induced Adverse Effects of Three Statins Following Single or Repetitive Treatments in Mice.

Background and objective The hypolipidemic statins have been associated with various side effects, and in some cases, adverse reactions in humans and experimental animals, such as myotoxicity, neurobehavioral toxicity, as well as liver and kidney injuries. The purpose of the present study was to examine the possibility of the induction of oxidative stress in the brain and plasma of mice dosed with single or repetitive doses of three statins (atorvastatin, simvastatin, and rosuvastatin). Methods Male Swiss-origin mice were dosed orally with single doses of each of the three statins at 500 or 1000 mg/kg of body weight.

Plasma Cholinesterase Activity in Patients With Rheumatoid Arthritis and Toxoplasmosis.

Background and objective Rheumatoid arthritis (RA) is a chronic autoimmune disease causing synovium inflammation and functional impairment. Toxoplasmosis is an intracellular zoonotic parasitic infection and a risk factor in immunosuppressed diseases including RA. The involvement of the cholinergic mechanism is not clear when both diseases exist in combination.

Polypharmacy and the In Silico Prediction of Potential Body Proteins Targeted by These Drugs Among Hospitalized COVID-19 Patients With Cytokine Storm.

Background and objective Polypharmacy is prevalent in coronavirus disease 2019 (COVID-19) patients with severe disease. However, information on polypharmacy among COVID-19 patients who also suffer from cytokine storm is scarce. In light of this, the purpose of the present study was to assess the incidence of polypharmacy and in silico prediction of potential body proteins targeted by these drugs among hospitalized COVID-19 patients who were identified to have the additional burden of cytokine storm in the city of Duhok, Kurdistan Region, Iraq.

Genomic analysis of SARS-CoV-2 omicron sublineage BA.5.2.1 in Erbil/Iraq.

Due to several mutations in its genomic sequence, particularly in the spike protein region, the recently-discovered SARS-CoV-2 variant B.5.2.

Experimental study of thermal conductivity coefficient of GNSs-WO3/LP107160 hybrid nanofluid and development of a practical ANN modeling for estimating thermal conductivity.

In the present study, the effects of nanoparticles, mass fraction percentage and temperature on the conductive heat transfer coefficient of Graphene nanosheets- Tungsten oxide/Liquid paraffin 107160 hybrid nanofluid was investigated. For this purpose, four different mass fractions were used in the range of 0.005%-5% in a number of examinations.

Investigation of the effects of porosity and volume fraction on the atomic behavior of cancer cells and microvascular cells of 3DN5 and 5OTF macromolecular structures during hematogenous metastasis using the molecular dynamics method.

Background And Objective: The molecular dynamics (MD) simulation is a powerful tool for researching how cancer patients are treated. The efficiency of many factors may be predicted using this approach in great detail and with atomic accuracy.

Methods: The MD simulation method was used to investigate the impact of porosity and the number of cancer cells on the atomic behavior of cancer cells during the hematogenous spread.

Effects of chopped CFRP fiber on mechanical properties of concrete.

Enhancing concrete's mechanical properties has become a prominent field in recent years. Numerous studies investigated the possibility of enhancing the mechanical properties of concrete by adding additive materials. Few studies investigated the effects of copped CFRP on the tensile strength of normal-strength concrete (NSC) and low-strength concrete (LSC).

Mode-locked ytterbium-doped fiber laser with zinc phthalocyanine thin film saturable absorber.

A stable mode-locked laser was demonstrated using a newly developed zinc phthalocyanine (ZnPc) thin film as passive saturable absorber (SA) in ytterbium-doped fiber laser (YDFL). The ZnPc thin film was obtained using a casting method and then inserted between the two fiber ferrules of a YDFL ring cavity to generate mode-locked pulses. The resulting pulsed laser operated at a wavelength of 1034.

Novel Correlation for Calculating Water Saturation in Shaly Sandstone Reservoirs Using Artificial Intelligence: Case Study from Egyptian Oil Fields.

The accurate determination of water saturation in shaly sandstone reservoirs has a significant impact on hydrocarbons in place estimation and selection of possible hydrocarbon zones. The available numerical equations for water saturation estimation are unreliable and depend on laboratory core analysis. Therefore, this paper attempts to use artificial intelligence methods in developing an artificial neural network model (ANN) for water saturation (Sw) prediction.

Finite Element Model to Simulate Two-Phase Fluid Flow in Naturally Fractured Oil Reservoirs: Part I.

Naturally fractured reservoirs host more than 20% of the world's total oil and gas reserves. To produce from such reservoirs efficiently, a good understanding of the reservoir behavior at various conditions is essential. This allows us to predict the reservoir performance in advance and assess its economic feasibility.

Green communication for cognitive radio networks based on game and utility-pricing theories.

The most crucial challenge in the functioning of the wireless networks is the efficient utilization of radio resources. A significant element of resource handling is power regulation. With increasing requirement of wireless data transmission services, it is essential to devise energy harvesting techniques for mobile devices.

Parental Discipline and Child Psychosocial Outcomes in Iraq and Kurdistan: Evidence From a Nationally Representative Sample.

Few empirical studies have been conducted on populations in the Middle-East, particularly in Iraq and Iraqi Kurdistan, regarding the relationships between the type of discipline used by caregivers and its subsequent effect on children. Our analyses, which are based on data from the Iraq Multi-Cluster Survey 2018, replicate the prior work of scholars using Western samples, and suggest that variation in parental practices pertaining to the discipline of children is a robust predictor of several negative psychosocial outcomes among Iraqi and Kurdish youth. Specifically, we found that children who were subjected to various forms of violent physical discipline, psychological aggression, and neglectful parenting were more likely to exhibit an array of symptoms of psychosocial disorder, relative to measures of adequate parenting.