27,629 results match your criteria: "American Journal Of Medicine[Journal]"

Objectives: This study aimed to compare the demographic features and socioeconomic status of patients who underwent coronary artery calcium screening to that of their local population.

Background: Coronary artery calcium scores provide important evidence of subclinical atherosclerosis. However, insurance often does not cover coronary artery calcium testing, which could exclude people of lower socioeconomic status.

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Comparative Analysis of First-Line Antihypertensive Treatment Classes.

Am J Med

October 2024

Department of Internal Medicine B, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: The best first-line monotherapy for hypertension remains uncertain, as current guidelines suggest that thiazides, angiotensin-converting enzyme inhibitors (ACEis), angiotensin receptor blockers (ARBs), and calcium channel blockers (CCBs) are appropriate in the absence of specific comorbidities. We aimed to compare the outcomes of first-line antihypertensive classes in a real-life setting with a long follow-up period.

Methods: This nationwide retrospective new-user cohort study included patients insured by the largest health maintenance organization in Israel.

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Post-Acute COVID-19 Syndrome: Prevalence of Peripheral Microvascular Endothelial Dysfunction and Associations with NT-ProBNP Dynamics.

Am J Med

October 2024

Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

Article Synopsis
  • Post-acute COVID-19 syndrome (PACS) occurs in patients even after mild infections, and this study investigates the link between PACS and microvascular endothelial dysfunction.* -
  • Out of 92 PACS patients, 41% showed signs of microvascular endothelial dysfunction, with increased levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) correlated to this dysfunction.* -
  • The findings suggest that microvascular endothelial dysfunction is common in PACS, particularly in those with rising NT-proBNP levels, highlighting the need for further research on this condition.*
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A Persistent Abdominal Pain With High Blood Pressure.

Am J Med

October 2024

Emergency Department, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; Faculté de médecine, Université de Strasbourg, Strasbourg, France. Electronic address:

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Background: Postlicensure observational studies are the mainstay of vaccine safety evaluation. However, these studies have well-known methodological limitations, rendering them particularly vulnerable to unmeasured confounding. We sought to describe high-impact observational studies of vaccine safety, investigate the authors' attitudes toward their study's findings and limitations, and report on spin practices.

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Veins Tell the Tale: Visible Clues of Budd-Chiari Syndrome.

Am J Med

October 2024

Department of Emergency and General Medicine, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, Japan. Electronic address:

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Fitz-Hugh-Curtis Syndrome.

Am J Med

October 2024

Department of General Medicine, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan; Department of General Medicine, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan.

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Effectiveness of Audit and Feedback and Academic Detailing Interventions to Support Safer Opioid Prescribing in Primary Care.

Am J Med

January 2025

Women's College Research and Innovation Institute, Women's College Hospital, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Article Synopsis
  • Opioids, while commonly prescribed for pain management, pose safety risks; the study explores whether strategies like audit and feedback can improve prescription practices among primary care physicians in Ontario.
  • The research used a matched-cohort design to compare the effects of audit and feedback, with or without academic detailing, on opioid prescribing rates over a 30-month period, focusing on family physicians.
  • Results indicated a general decline in opioid prescriptions pre-intervention across all groups, with significant reductions in high-prescribing physicians in the audit and feedback group, but no notable difference post-intervention between the groups, suggesting future efforts should target high-volume prescribers.
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Rethinking Our Roots: The Ground-Up Approach to Heart Health & Planetary Sustainability.

Am J Med

October 2024

Division of Cardiology, University of Florida, Gainesville; Cardiologist, Advent Health, Orlando, FL; CHIEF MEDICAL OFFICER, 4Roots Farm, Orlando, FL. Electronic address:

Article Synopsis
  • * Our food system is influenced by complex agricultural practices and human behaviors, requiring a deeper understanding and reforms in nutrition education, food insecurity, and nutritional security.
  • * Plant-forward diets are highlighted as a key solution to improve individual health and environmental sustainability, linking human health and planetary health through better dietary practices.
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The Four Ts of Mentoring Minorities.

Am J Med

January 2025

Department of Medicine, The Ottawa Hospital, Ottawa, Canada; The Ottawa Hospital, Research Institute (OHRI), Ottawa, Canada; School of Public Health and Epidemiology, University of Ottawa, Ottawa, Canada. Electronic address:

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Increased Risk of Chronic Respiratory Disease among Individuals with Inflammatory Bowel Disease in a Prospective Cohort Study.

Am J Med

January 2025

Department of Big Data in Health Science School of Public Health, Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

Background: Cross-sectional evidence suggests a higher burden of chronic respiratory diseases in people with inflammatory bowel disease, but there is a lack of prospective evidence to clarify the direction of their associations. We aimed to investigate the association of inflammatory bowel disease with the risk of 2 major chronic respiratory diseases, chronic obstructive pulmonary disease, and asthma.

Methods: We included 430,414 participants from UK Biobank and followed them from recruitment (2006-2010) to 2021.

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Misconceptions and Facts About Orthostatic Hypotension.

Am J Med

October 2024

Beth Israel Deaconess Medical Center, Harvard Medical School, Department of Medicine, Division of General Medicine, Boston, Mass.

Article Synopsis
  • Orthostatic hypotension is when your blood pressure drops a lot when you stand up, making you feel dizzy or weak.
  • It can cause falls and other serious health problems but many people don’t know they have it because they don't always feel symptoms.
  • There are also common misunderstandings about this condition that make it harder to recognize and treat.
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Low-Risk Chest Pain Patients: Exploring the Impact of Socioeconomy on Emergency Department Revisits.

Am J Med

October 2024

Theme of Acute and Reparative Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden; Department of Medicine, Clinical Epidemiology Division, Karolinska Institutet, Solna, Stockholm, Sweden.

Article Synopsis
  • * Analysis of data from over 61,000 patients revealed that those with lower disposable income had a significantly higher risk of revisiting the ED within 30 days and during long-term follow-ups compared to those with higher income.
  • * Despite the high revisit rates, overall cardiovascular event risks were low across different income levels, indicating that while income may influence ED utilization, the long-term health risks for this patient group remain minimal.
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Article Synopsis
  • - This review investigates cognitive and immune differences in individuals suffering from post-COVID syndrome, focusing on changes occurring twelve or more weeks after COVID-19 infection.
  • - Eleven studies were analyzed, revealing significant cognitive impairments, particularly in executive function, alongside increased inflammation markers in post-COVID patients compared to healthy controls.
  • - The findings suggest a link between elevated immune responses and cognitive deficits, indicating immune status may predict cognitive function after COVID-19 infection.
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Vitamin K Antagonist Anticoagulation in Antiphospholipid Syndrome: Time in Therapeutic Range and Clinical Outcomes.

Am J Med

October 2024

School of Medicine, Faculty of Medicine and Health Sciences, Tel Aviv University, Israel; Hematology Institute and Blood Bank, Meir Medical Center, Kfar Saba, Israel. Electronic address:

Article Synopsis
  • Antiphospholipid syndrome patients often receive vitamin K antagonists, but only 29.9% achieve an optimal therapeutic range (INR ≥ 70%), which is linked to better outcomes.* -
  • Those with three or more comorbidities are significantly less likely to reach this therapeutic range (9.1%) compared to those with fewer comorbidities (40%).* -
  • Patients maintaining an INR ≥ 70% experience fewer recurrent thrombotic events, particularly arterial ones, highlighting the need for close monitoring in this population.*
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New Clinical and Public Health Challenges in Vaccinations in US Adults.

Am J Med

September 2024

Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton; Departments of Medicine & Populations Health and Social Medicine, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton. Electronic address:

Article Synopsis
  • Rising recidivism is threatening the positive effects of vaccinations in the US, largely due to vaccine hesitancy and other complex factors.
  • The future looks promising thanks to advancements in vaccine technology and the commitment of healthcare professionals and public health systems, which are crucial for eliminating infectious diseases.
  • To effectively increase vaccination rates, healthcare providers must focus on rapid detection, isolation, and a comprehensive response strategy, including antiviral medications and social distancing measures.
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Article Synopsis
  • - The study investigates HIV-related mortality trends among young adults in the U.S. from 1999 to 2020, revealing significant demographic and regional differences in mortality rates.
  • - Findings show that while the age-adjusted mortality rates (AAMRs) declined from 1999 to 2018, there was a stabilization from 2018 to 2020, with males and non-Hispanic Blacks experiencing much higher death rates compared to females and Whites, respectively.
  • - The Southern region of the U.S. and urban areas reported notably higher mortality rates, urging the need for urgent action to address these disparities in HIV-related deaths.
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Use of Complementary Medicine Among US Adults with Post-COVID-19: Results from the 2022 National Health Interview Survey.

Am J Med

September 2024

Institute of General Practice and Interprofessional Care, University Hospital Tübingen, Tübingen, Germany & Bosch Health Campus, Stuttgart, Germany.

Objective: The aim of this study was to investigate the prevalence and type of complementary medicine (CM) use as well as potential factors related to CM use in a representative sample of US adults with self-reported post-COVID-19.

Methods: This secondary data analysis was based on data from the 2022 National Health Interview Survey 2022 about presence of post-COVID-19 symptoms and CM use in a representative adult sample (weighted n = 89,437,918).

Results: Our estimates indicate that 19.

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Red Lunulae, White Nails, and Cirrhosis.

Am J Med

January 2025

Department of Emergency and General Medicine, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, Japan. Electronic address:

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