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INTRAVITREAL DEXAMETHASONE IMPLANT AS ADJUVANT TREATMENT FOR BEVACIZUMAB- AND RANIBIZUMAB-RESISTANT NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Prospective Pilot Study.

Retina

July 2017

*Department of Ophthalmology, American University of Beirut, Beirut, Lebanon; †Department of Ophthalmology, American Hospital of Dubai, Dubai, United Arab Emirates; and ‡Department of Health Policy and Research, Weill Cornell Medicine, Doha, Qatar.

Purpose: To study the benefit of intravitreal dexamethasone implant in the management of neovascular age-related macular degeneration resistant to bevacizumab and ranibizumab.

Methods: Patients with persistent macular fluid on optical coherence tomography despite monthly treatment with at least three consecutive bevacizumab injections followed by at least three ranibizumab injections were prospectively enrolled. A single dexamethasone implant was administered followed by intravitreal ranibizumab 1 week later.

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