10,874 results match your criteria: "Amblyopia"

Effects of Prolonged Waiting Time on Visual Outcomes of Patients with Pediatric Cataract in a Tertiary Public Hospital.

Acta Med Philipp

September 2024

Department of Ophthalmology and Visual Sciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

Article Synopsis
  • Pediatric cataracts are a major preventable cause of childhood blindness, and early intervention is crucial for improving visual outcomes and rehabilitation.
  • This study analyzed medical records to assess the time from initial consult to cataract surgery and how delays affected visual results, focusing on a range of patients from 2015 to 2022.
  • Results showed that, despite quicker surgeries during the pandemic, overall waiting times remained the same, and no significant differences were found in visual outcomes between those who had surgery immediately versus those who experienced delays.
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Pediatric keratoconus.

Surv Ophthalmol

October 2024

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India. Electronic address:

Keratoconus is a common pediatric corneal disease, leading to vision impairment and amblyopia. Compared to its adult counterpart, pediatric keratoconus has an advanced presentation, rapid progression, higher incidence of complications such as corneal hydrops, and greater potential impact on the quality of life. It typically manifests during puberty and can evolve rapidly to more severe stages if left untreated.

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Refractive surgery is one of the most commonly performed elective procedures in ophthalmology; it is mostly performed in patients who are older than 18 years of age. This routine procedure has been time-tested and is proven to be both safe and effective in adults. However, little is known about the safety and efficacy of refractive surgery in pediatric patients.

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Article Synopsis
  • A study evaluated three treatments for amblyopia in children, comparing two methods that included patching with active vision therapy and one method that used patching alone.
  • Results showed significant improvement in visual acuity (VA) and stereoacuity (STA) for the groups that combined patching with vision therapy or monocular perceptual learning, while patching alone was the least effective.
  • The findings suggest that effective amblyopia treatment should involve active vision exercises alongside patching to enhance visual performance, particularly for children with poorer initial vision.
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Article Synopsis
  • - The study investigates how fixational eye movements (FEMs) vary among children, adolescents, and adults under different viewing conditions (binocular and monocular).
  • - A total of 68 healthy participants were divided into three age groups and assessed for various metrics including fixation stability and saccade characteristics using a high-resolution video tracker.
  • - Results show that younger children demonstrate more fixation instability and larger saccade amplitudes compared to adults, but factors like inter-ocular fixation stability remain consistent across age groups, suggesting their utility in diagnosing conditions like amblyopia.
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Epidemiological Characteristics Associated with Astigmatism in a Population of 3- to 5-Year-Old Children in Los Angeles, CA.

Ophthalmic Epidemiol

October 2024

Department of Ophthalmology, Stein Eye Institute, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, USA.

Article Synopsis
  • The study aimed to assess the prevalence of astigmatism in a large group of 79,330 preschool children, focusing on different age, gender, and racial/ethnic subgroups.
  • Results showed that 11% of the children had astigmatism, with Latino children experiencing the highest rates and no decline in prevalence as they aged.
  • The findings highlight the importance of regular vision screenings in schools, particularly in Latino communities in Los Angeles, to address these disparities in eye health.
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Article Synopsis
  • Amblyopia is a neurodevelopmental visual disorder linked to poor depth perception, typically studied in animals using monocular deprivation during critical visual development stages.
  • This study assessed two behavioral tests, the Visual Cliff Assay (VCA) and the Pole Descent Cliff Task (PDCT), to evaluate their effectiveness in detecting binocular issues in mice, especially after manipulating vision.
  • Results showed that while both tests were useful, the PDCT was more effective in identifying stereoscopic deficits with fewer mice needed, establishing it as a valuable tool for future studies on binocular vision and amblyopia treatment.
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Clinical Relevance: Vision screening is important for detecting undiagnosed vision conditions that are common in school-aged children. However, current vision screening protocols are poor at detecting vision conditions that are most common in the Aotearoa New Zealand paediatric population.

Background: Uncorrected refractive error and amblyopia are the most common causes of visual impairment in children.

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A retinal detachment based strabismus detection through FEDCNN.

Sci Rep

October 2024

Artificial Intelligence and Data Analytics (AIDA) Lab, CCIS, Prince Sultan University, Riyadh, 11856, Saudi Arabia.

Article Synopsis
  • - Ocular strabismus is a widespread issue that can lead to serious visual problems like amblyopia, yet diagnosing it accurately remains difficult despite advancements in eye-tracking technology.
  • - The study introduces a novel model, FedCNN, which integrates Convolutional Neural Networks (CNNs) and eXtreme Gradient Boosting (XGBoost) to improve the precision of strabismus detection using dynamic eye movement data.
  • - With an impressive diagnostic accuracy of 95.2%, this innovative approach has the potential to significantly improve eye disease diagnosis for many patients.
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Article Synopsis
  • The study aimed to compare the effectiveness of a new 4D digital visual function correction system (4D-DSAAVFCS) combined with standard treatments against standard treatments alone for treating anisometropic amblyopia in children.
  • Data was collected on various visual functions like best-corrected visual acuity and stereoscopic vision from 393 children aged 3 to 12 over a year, using different statistical tests to analyze the results.
  • Results indicated that the group using the 4D system had a significantly higher cure rate compared to the traditional treatment group, although no substantial differences were found in other visual measurements such as BCVA and latency of P100 wave.
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Article Synopsis
  • The study analyzes data from the Primary School Nurse Health Readiness Program (PSNHRP) in Queensland, Australia, to understand the prevalence of visual impairments in children aged 4 to 7 over a four-year period.
  • Out of 164,890 screened children, 12,148 (7.4%) failed the screening and 6,011 of those who attended further review were diagnosed with a visual abnormality, showcasing significant rates of conditions like anisometropia and refractive errors.
  • The findings suggest that certain visual abnormalities were more common in females except for anisometropic amblyopia, highlighting the need for better understanding of risk factors to enhance future vision screening efforts.
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Article Synopsis
  • In binocular vision, the balance between the inputs from each eye is crucial, and conditions like amblyopia can cause one eye to dominate over the other.
  • The Dichoptic Contrast Ordering Test (DiCOT) is a new tool designed to measure these imbalances by using perceived contrast rankings on a tablet device.
  • Results show that while both DiCOT and the Dichoptic Letter Test (DLT) are reliable, they highlight different aspects of binocular imbalance, suggesting that using both tests together could enhance future research.
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Article Synopsis
  • Hubel and Wiesel's research in the 1950s and 1960s transformed visual neuroscience by discovering key concepts like orientation selectivity, where neurons react specifically to line orientations, aiding in edge detection.
  • They identified ocular dominance columns, which are areas in the visual cortex that preferentially process input from one eye, highlighting the importance of binocular vision.
  • Their work revealed the critical period for visual development, showing that early visual experiences are vital for a properly functioning visual system, influencing both therapeutic strategies for visual disorders and current research on brain plasticity.
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Introduction: Little is known about the prevalence of refractive errors and amblyopia among school children on the islands of East Coast Malaysia. This study aimed to investigate the prevalence of these conditions and their associated factors in this unique and remote geographical location.

Materials And Methods: This multicentre cross-sectional school-based study included 480 children aged 7 to 12 year from primary schools on the islands of the East Coast of Malaysia.

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Disparities in Amblyopia Treatment Outcomes: The Impact of Sociodemographic Factors, Treatment Compliance, and Age of Diagnosis.

Ophthalmology

September 2024

Department of Ophthalmology, University of Southern California, Los Angeles, California; Division of Ophthalmology, Children's Hospital Los Angeles, Los Angeles, California. Electronic address:

Article Synopsis
  • The study aimed to find out what clinical and sociodemographic factors affect the success of amblyopia (lazy eye) treatment in children.
  • It analyzed data from 168 children who were diagnosed and treated for amblyopia between 2012 and 2022, focusing on whether their condition improved or persisted.
  • The findings revealed that younger age at diagnosis, higher income, and being a native English speaker were linked to better treatment outcomes, while factors like being on government insurance showed a potential connection to poorer outcomes.
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Article Synopsis
  • * A 32-year-old woman experienced sudden vision loss in her right eye and was found to have extensive myelinated retinal nerve fibers and a retinal detachment, leading to a complex surgical procedure.
  • * The surgery successfully closed the macular hole and reattached the retina, showcasing the effectiveness of the PFCL-assisted inverted ILM flap technique for difficult cases of MHRD, while also raising questions about potential damage to the nerve fibers from the detachment or treatment.
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Introduction And Clinical Importance: Goldenhar syndrome (GS) manifests as a triad of ocular, auricular, and vertebral anomalies. We present a rare case report presenting with monocular elevation deficiency (MED) in association with GS secondary to radiologically proven vascular insufficiency.

Case Presentation: A 9-year-old male presented with drooping of the upper eyelid in the right eye (OD), absence of right ear, and swelling near the ear remanent.

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Background Amblyopia, often linked to high astigmatism in children, presents challenges in understanding the contributing factors and visual outcomes. Methods A total of 132 samples were included in this prospective pre- and post-interventional study using the purposive sampling technique. Descriptive statistics were applied for age, gender, uncorrected visual acuity, corrected visual acuity, type, and magnitude of astigmatism.

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True or pseudo optic disc edema: clinically-based approach to the differential diagnosis.

Int Ophthalmol

September 2024

Dünyagöz Hospital, Halk Sokak, No: 26, Sahilevleri, 35320, Narlıdere, İzmir, Türkiye.

Article Synopsis
  • This study focuses on differentiating cases of optic disc edema (DE), a condition frequently encountered in neuro-ophthalmology, through clinical evaluations.
  • It involved 119 patients, finding that 75% had true optic disc edema (ODE) caused by conditions like non-arteritic anterior ischemic optic neuropathy, while the remaining 25% had pseudo optic disc edema (PODE) due to anatomical variations.
  • The research highlights the importance of thorough history and neuro-ophthalmological exams in achieving a preliminary diagnosis with an accuracy of 79%.
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Purpose: To evaluate the effects of oral fluoxetine on visual acuity and visual-evoked potential (VEP) parameters in adults patching for amblyopia.

Methods: In this randomized clinical trial, adults (>18 years of age) with anisometropic or strabismic amblyopia were assigned randomly to a treatment (fluoxetine) group or a placebo group. Standard treatments for amblyopia (glasses prescription and patching) were prescribed for 4 months for all patients beforehand.

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Purpose: To assess the validity of the GoCheck Kids photoscreening application (Gobiquity Mobile Health, Scottdale, AZ) on iPhone, which was used (2018-2022) as standard of care by Child and Family (Kind en Gezin) to detect amblyopia risk factors in children 12-30 months of age.

Methods: Between August 2021 and May 2022, 453 children 11-16 months of age underwent a confirmatory ophthalmic examination within 2 months of GoCheck Kids photoscreening at Child and Family, Flanders, Belgium. Additionally, manual review was performed by specialists of GoCheck Kids.

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Article Synopsis
  • A risk factor model was developed to predict the likelihood of posterior capsule rupture (PCR) during cataract surgery based on data from over 961,000 operations between 2016 and 2022 in the UK.
  • Key factors contributing to a higher risk of PCR included less experienced trainee surgeons, existing eye conditions like pseudoexfoliation, younger males, and advanced cataracts.
  • The model helps assess individual risks for patients and supports surgeons in adjusting their surgical strategies based on the complexity of cases to better manage PCR rates.
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Unilateral pigmented posterior lenticonus with retinochoroidal coloboma: a case report.

J AAPOS

October 2024

Department of Pediatric Ophthalmology and Strabismus, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Posterior lenticonus is a rare congenital anomaly of the crystalline lens characterized by the conical herniation of the posterior lenticular surface with or without cortex herniation into the anterior vitreous. It is usually unilateral and axial; bilateral cases are usually familial and have syndromic associations. The irregular lenticular surface produces high myopia and irregular astigmatism producing optical distortion and hence deprivation amblyopia.

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Posterior subcapsular cataract in a patient with Straatsma syndrome.

J AAPOS

October 2024

Department of Ophthalmology, Mayo Clinic Rochester, Rochester, Minnesota. Electronic address:

Article Synopsis
  • - Straatsma syndrome is a rare eye condition that includes myelinated retinal nerve fibers, nearsightedness (myopia), and reduced vision (amblyopia)! - It can be linked to other eye issues like crossed eyes (strabismus), uncontrollable eye movements (nystagmus), underdeveloped optic nerve (optic nerve hypoplasia), and differences in iris color (iris heterochromia)! - The case presented is of a 6-year-old girl with the syndrome in one eye, who also developed a cataract that needed surgical removal!
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