Correction to: Drug repurposing using computational methods to identify therapeutic options for COVID-19.

[This corrects the article DOI: 10.1007/s40200-020-00546-9.].

Non-viral and viral delivery systems for hemophilia A therapy: recent development and prospects.

Recent advancements have focused on enhancing factor VIII half-life and refining its delivery methods, despite the well-established knowledge that factor VIII deficiency is the main clotting protein lacking in hemophilia. Consequently, both viral and non-viral delivery systems play a crucial role in enhancing the quality of life for hemophilia patients. The utilization of viral vectors and the manipulation of non-viral vectors through targeted delivery are significant advancements in the field of cellular and molecular therapies for hemophilia.

Functional analysis of a putative HER2-associated expressed enhancer, Her2-Enhancer1, in breast cancer cells.

HER-2/neu (HER2) is a member of the epidermal growth factor receptors family, encoding a protein with tyrosine kinase activity. Following the gene amplification or increased HER2 transcription, carcinogenesis has been observed in some cancers. Genetic and epigenetic changes occurring in enhancer sequences can deeply affect the expression and transcriptional regulation of downstream genes, which can cause some physiological and pathological changes, including tumor progression.

A new nanobiotic: synthesis and characterization of an albumin nanoparticle with intrinsic antibiotic activity.

Background And Objectives: With entering the "post-antibiotic era", antibiotic resistance is one of the most important problems in food security, health and medicine. Invention of nanoparticles with intrinsic antimicrobial activity has been provided a new tool to combat the problem, including some metal nanoparticles. But protein nanoparticles have been often used as nano-carrier for antibiotic drugs, not for their own antibiotic activity.

Natural Phenolic Compounds with Neuroprotective Effects.

Neurodegenerative disorders are characterized by mitochondrial dysfunction and subsequently oxidative stress, inflammation, and apoptosis that contribute to neuronal cytotoxicity and degeneration. Huntington's (HD), Alzheimer's (AD), and Parkinson's (PD) diseases are three of the major neurodegenerative diseases. To date, researchers have found various natural phytochemicals that could potentially be used to treat neurodegenerative diseases.

Biochemical changes and enhanced accumulation of phenolic compounds in cell culture of Perilla frutescens (L.) by nano-chemical elicitation.

Perilla frutescens (L.) Britt is a renowned medicinal plant with pharmaceutically valuable phenolic acids and flavonoids. The present study was aimed to study the eliciting effect of silver and copper nanoparticles (AgNPs and CuNPs, 50 and 100 mg/L), and methyl jasmonate (MeJa, 50 and 100 μM) on the biochemical traits, the accumulation of phenolic compounds and antioxidative capacity of P.

Validation of the online version of the sharenting evaluation scale (SES) in Iranian parents: Psychometric properties and concurrent validity.

Introduction: This study examines the psychometric properties of the online version of the sharenting evaluation scale (SES) with a sample of Iranian parents.

Methods: A sample population of 240 parents (25% fathers and 75% mothers) with an average age of 39.63 (standard deviation = 10.

Prevention and control of violence and aggression in football fans: Implications for sport psychologists, fans, and policymakers.

This research was conducted to design an interpretive structural model of factors affecting the prevention and control of violence and aggression in football fans. The statistical population of this study was entirely composed of sport experts, executive managers, sociologists, and management professors in Iran. Thirteen individuals were accordingly selected as the research sample using non-probability purposeful sampling.

Enhancing Rheological and Textural Properties of Gelatin-Based Composite Gels through Incorporation of Sesame Seed Oleosome-Protein Fillers.

In this study, the protein and oleosomes of sesame seeds were extracted individually and used to prepare a gel composed of gelatin, protein, and oleosomes. Mixtures of gelatin and sesame seeds protein were prepared, and oleosomes with different percentages (0, 10, 20 and 30% of their weight) were used. Different amounts of oleosomes in the composite gel samples were examined for their morphological, rheological, and textural properties.

Molecular study on virulence and resistance genes of ST131 clone (uropathogenic/enteropathogenic ) hybrids in children.

To analyze ST131 clones and other characteristics in uropathogenic and atypical enteropathogenic hybrids. Samples were collected from children with urinary tract infections and underwent testing for antimicrobial susceptibility, multidrug resistance and extended-spectrum β-lactamases, biofilm formation and virulence, resistance genes, hybrid pathotypes and ST131 clones. isolates showed high levels of antibiotic resistance, extended-spectrum β-lactamase production, virulence genes, multidrug resistance and biofilm formation.

Enhanced removal of organic dyes from aqueous solutions by new magnetic HKUST-1: facile strategy for synthesis.

A novel, magnetic HKUST-1 MOF based on MgFeO-NH was designed and synthesized in two steps and applied effective removal of malachite green (MG), crystal violet (CV), and methylene blue (MB) from water samples. Characterization of the newly synthesized MgFeO-NH-HKUST-1 was performed by various techniques such as Fourier transform infrared spectroscopy, X-ray diffraction, Field emission scanning electron microscopy, Brunauer-Emmett-Teller, Thermal gravimetric analysis, and Vibration sampling magnetometry. Malachite green, crystal violet and methylene blue are toxic and mutagenic dyes that can be released into the water in different ways and cause many problems for human health and the environment.

Molecular genetics, seed morphology and fatty acids diversity in castor (Ricinus communis L., Euphorbiaceae) Iranian populations.

Background: Castor (Ricinus communis L.) seeds contain a large amount of oil that has several biological activities. In the current research, phytogeographic distribution, seed morphological characteristics, molecular genetic diversity and structure, and fatty acid composition were investigated in nine Iranian castor populations.

Ionothermal synthesis of magnetic N-doped porous carbon to immobilize Pd nanoparticles as an efficient nanocatalyst for the reduction of nitroaromatic compounds.

Carbon materials play important roles as catalysts or catalyst supports for reduction reactions owing to their high porosity, large specific surface area, great electron conductivity, and excellent chemical stability. In this paper, a mesoporous N-doped carbon substrate (exhibited as N-C) has been synthesized by ionothermal carbonization of glucose in the presence of histidine. The N-C substrate was modified by FeO nanoparticles (N-C/FeO), and then Pd nanoparticles were stabilized on the magnetic substrate to synthesize an eco-friendly Pd catalyst with high efficiency, magnetic, reusability, recoverability, and great stability.

Preparation of magnetic biochar functionalized by polyvinyl imidazole and palladium nanoparticles for the catalysis of nitroarenes hydrogenation and Sonogashira reaction.

Catalysts are essential materials in biotechnology, medicine, industry, and chemistry. On the other hand, recycling and using waste materials is important in economic efficiency and green chemistry. Thus, biochar was prepared from the stem and roots of the Spear Thistle to recover waste.

Nanoarchitectonics of doxycycline-loaded vitamin E-D-α-tocopheryl polyethylene glycol 1000 succinate micelles for ovarian cancer stem cell treatment.

This study aim to develop doxycycline within the D-α-tocopheryl polyethylene glycol 1000 succinate micelle platform as an anticancer stem cell agent. The optimized nanomicelle formulation was prepared using the solvent casting method and evaluated through physicochemical and biological characterization. Nanomicelles exhibited mean particle sizes of 14.

Pyrazole-promoted synthesis of pyrrolo[3,4-c] quinoline-1,3-diones in a novel diketene-based reaction.

We describe the first classic example of green synthesis of pyrrolo[3,4-c]quinolones scaffolds by catalyst-free unusual reaction of diketene, isatin, and primary amines in ethanol in the presence of pyrazole as a promoter for 4 h. The whole structure of the new product was confirmed by X-ray analysis. The overall transformation involves the cleavage and generation of multiple carbon-nitrogen and carbon-carbon bonds.

Psychometric properties of persian version of escapism scale among Iranian adolescents.

The aim of this study was to assess the psychometric properties of the Persian version of the Escapism Scale among Iranian adolescents aged 14-18. Between January 2021 and August 2021, cross-sectional study was conducted using a convenience sampling method to select 566 participants (340 girls and 226 boys) to investigate the relationship between physical activity and mental health in adolescents. The participants completed several questionnaires, including the Escapism Scale, Erikson Psychosocial Stage Inventory (EPSI), Satisfaction with Life Scale (SWLS), Hope Scale (AHS), Smartphone Addiction Scale-Short Version (SAS-SV), and General Self-efficacy (GSE).

Novel probe based on rhodamine B and quinoline as a naked-eye colorimetric probe for dual detection of nickel and hypochlorite ions.

This work demonstrates the design and straightforward syntheses of several novel probe-based on rhodamine B and 2-mercaptoquinoline-3-carbaldehydes as a naked-eye colorimetric probe, indicating a sensitive and selective recognition towards nickel (II) with a limit of detection 0.30 μmol L (0.02 mg L).

The relationship between perfectionism and interpersonal sensitivity with self-compassion in university students: the mediation of repetitive negative thinking.

Self-compassion is a construct of positive psychology related to personality and cognitive factors. Perfectionism and interpersonal sensitivity are prevalent personality traits among university students and are associated with low self-compassion. Further research is required to comprehend how these mechanisms work in creating self-compassion.

Efficient oxidation of sulfides to sulfoxides catalyzed by heterogeneous Zr-containing polyoxometalate grafted on graphene oxide.

In this study, a tri-component composite named Zr/SiW/GO was meticulously prepared through an ultrasonic-assisted method. This composite incorporates zirconium nanoparticles (Lewis acid), a negatively charged Keggin type polyoxometalate, and graphene oxide, and serves as a remarkable heterogeneous catalyst. The Keggin component plays multiple roles as reducing, encapsulating, and bridging agents, resulting in a cooperative effect among the three components that significantly enhances the catalytic activity.

The mediating role of outgroup perspective-taking in the relationship of the sense of global social responsibility with negative stereotypes and intergroup anxiety.

Existing literature has extensively explored attitudes toward refugees; however, to the best of our knowledge, no study has specifically examined the relationship between the sense of global social responsibility and attitudes toward refugees. Therefore, this study investigated the mediating role of outgroup perspective-taking in the relationship of the sense of global social responsibility with negative stereotypes and intergroup anxiety. The data for this study were collected from a sample of 325 participants, with 53.

Evaluation of reliability and validity of the Persian version of Peters et al. delusions inventory (PDI-40) in iranian non-clinical and clinical samples.

Background: Some individuals may manifest psychotic symptoms that do not fulfill the requisite clinical criteria for a formal diagnosis of psychosis. The assessment of susceptibility to delusions, encompassing both clinical and non-clinical cohorts, frequently makes use of the Peters et al. Delusions Inventory (PDI-40).

Effect of alloying Li on lithium-ion batteries applicability of two-dimensional TiN and TiC as novel electrode materials: a first principle study.

The two-dimensional structures of transition metal nitride and carbide, TiN, and TiC have been alloyed with lithium (Li) in replacement of Ti, and their Li-ion applicability has been investigated using density functional theory and general gradient approximation. The alloy composition of [Formula: see text], 0.25, 0.

Heteropolyacid supported on ionic liquid decorated hierarchical faujasite zeolite as an efficient catalyst for glycerol acetalization to solketal.

To handle huge amount of glycerol produced in biodiesel industry, glycerol is transformed to value-added products. In this regard, glycerol acetalization to solketal is industrially attractive. As in this process various by-products can be formed, designing highly selective catalysts is of great importance.