481 results match your criteria: "Alopecia Mucinosa"
Unilesional folliculotropic mycosis fungoides associated with follicular mucinosis in children: 2 cases and literature review.
Ann Dermatol Venereol
December 2024
Department of Dermatology, Saint-Vincent-de-Paul Hospital, Lille Catholic University, Lille, France.
A Case Report of Folliculotropic Mycosis Fungoides: Diagnostic Criteria and Treatment Strategy.
Cureus
October 2024
Department of Dermatology, Scientific/Research National Center of Dermatology and Venereology "Kanveni", Tbilisi, GEO.
Folliculotropic mycosis fungoides (F-MF) is considered a unique variant of mycosis fungoides (MF), which is a form of cutaneous T-cell lymphomas (CTCLs). F-MF can appear in various forms, including patches, papules, plaques, nodules, and tumors. It often affects the face and extremities, with some cases involving the eyebrows.
View Article and Find Full Text PDFHistopathologic Comparisons of Discoid Lupus Erythematosus and Folliculotropic Mycosis Fungoides in a Series of 43 Cases.
J Cutan Pathol
November 2024
Oakland University William Beaumont School of Medicine, Rochester Hills, Michigan, USA.
Background: Folliculotropic mycosis fungoides (FMF) is a rare cutaneous malignancy that can be mistaken for inflammatory diseases, such as discoid lupus erythematosus (DLE), due to the variability of histopathological findings.
Methods: This study aims to provide dermatopathologists with evidence-based histopathologic criteria to distinguish DLE from FMF by reporting overlapping and distinguishing microscopic features. Forty-three biopsies from patients with a confirmed diagnosis of DLE or FMF were graded for the presence or absence of 18 histopathologic features.
Article Synopsis
- Follicular Mycosis Fungoides (F-MF) is a rare variant of Mycosis Fungoides (MF), which is a type of skin lymphoma and should be considered when diagnosing hair loss.
- Accurate diagnosis of F-MF relies on a detailed medical history, physical exams, and a combination of immunohistological and molecular analyses.
- A case study of a 52-year-old man with recurrent scalp lesions demonstrated typical symptoms and histological features that led to a diagnosis of F-MF, highlighting the complexity of identifying this condition.
A case of generalized eosinophilic pustular folliculitis: treatment with JAK inhibitor.
J Dermatolog Treat
December 2024
Hospital for Skin Diseases, Shandong First Medical University, Jinan, Shandong, China.
Article Synopsis
- The case study investigates the effectiveness and safety of a Janus kinase (JAK) inhibitor for treating generalized eosinophilic pustular folliculitis (EPF) in a 16-year-old patient who did not respond to traditional treatments.
- The patient was initially treated with oral tofacitinib, resulting in significant symptom relief, but a relapse occurred when the dosage was reduced.
- A switch to the more selective JAK1 inhibitor upadacitinib led to complete recovery, suggesting that JAK inhibitors could be a viable option for EPF patients resistant to standard therapies.
The realistic positioning of UVA1 phototherapy after 25 years of clinical experience and the availability of new biologics and small molecules: a retrospective clinical study.
Front Med (Lausanne)
November 2023
Department of Dermatology, University of Brescia, Brescia, Italy.
Article Synopsis
- Ultraviolet (UVA) A1 phototherapy has been an effective treatment for various skin conditions since the 1990s, yet its application remains limited to a few dermatology centers even after 30 years.
- A study at a single center reviewed 740 patients treated from 1998 to 2022, assessing treatment outcomes and side effects, revealing significant improvements in several conditions, including morphea and skin sarcoidosis.
- Despite showing good efficacy, the usage of UVA1 phototherapy has decreased over the years due to multiple factors, including possible changes in clinical practices and alternatives available.
Folliculotropic Mycosis Fungoides In A Child: A Rare Case.
J Pak Med Assoc
November 2023
Department of Dermatology, PNS Shifa Hospital, Karachi, Pakistan.
Article Synopsis
- Folliculotropic mycosis fungoides (FMF) is a type of skin cancer that affects hair follicles, typically manifests as plaques and tumors, especially on the head and neck.
- It presents a variety of symptoms including prurigo-like lesions, cysts, and areas of scarring alopecia, with an average diagnosis age of 60 years, making it rare in younger people.
- A case study of a 12-year-old boy revealed an infiltrating plaque on his face that, upon biopsy, showed specific immune cell patterns confirming FMF diagnosis.
Patchy hair loss over the leg: a case of primary follicular mucinosis.
BMJ Case Rep
November 2023
Dermatology, All India Institute of Medical Sciences, Nagpur, Maharashtra, India.
Brownish-Yellow Dots as a Dermoscopic Sign of Follicular Mucinosis.
Dermatol Pract Concept
July 2023
Dermatology Department, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Papulonodular nonalopecic primary follicular mucinosis successfully treated with tacrolimus ointment.
Indian J Dermatol Venereol Leprol
November 2023
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
A novel application of dupilumab in treatment-resistant follicular mucinosis.
JAAD Case Rep
April 2023
Department of Dermatology, Icahn School of Medicine at Mount Sinai.
An atypical case of eosinophilic pustular folliculitis with associated secondary follicular mucinosis treated with indomethacin.
JAAD Case Rep
April 2023
Department of Dermatology, University of Utah Health, Salt Lake City, Utah.
Generalized lichen spinulosus and secondary follicular mucinosis.
JAAD Case Rep
March 2023
Division of Anatomical Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University and National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa.
An update on long-term outcomes of pediatric follicular mucinosis over a 20-year period: a retrospective cohort study.
Int J Dermatol
August 2023
Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
Article Synopsis
- Follicular mucinosis (FM) is a rare skin condition involving mucin buildup, often seen in children, with debates about its causes and potential for becoming malignant.
- A study investigated the long-term health outcomes of 14 pediatric patients diagnosed with FM, collecting data on their diagnosis, treatments, and health status.
- The results showed that none of the patients developed mycosis fungoides or other blood cancers, suggesting that FM in children is typically benign.
Clinicopathological features, therapeutic options, and significance of CD103 expression in 15 patients with follicular mucinosis.
Front Med (Lausanne)
February 2023
Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Article Synopsis
- Follicular mucinosis (FM) can be classified into primary benign and secondary forms associated with mycosis fungoides, which require careful distinction.
- A study involving 15 cases revealed that mycosis fungoides-associated FM has more pronounced lymphoid infiltrates and higher CD103 expression compared to primary FM.
- Treatment varied among patients, with some experiencing resolution after surgery, while others showed improvement with medication or phototherapy, indicating the importance of tailoring treatment to the specific type of FM.
Identifying the potential origin of mucin in primary cutaneous mucinoses-A retrospective study and analysis using histopathology and multiplex fluorescence staining.
J Eur Acad Dermatol Venereol
July 2023
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Article Synopsis
- Primary cutaneous mucinoses (PCM) are uncommon skin disorders where mucin accumulates in the dermis or hair follicles, and this study aims to explore their characteristics and potential cell sources at a single-cell level.
- The research involved 31 patients diagnosed with different forms of PCM from 2010 to 2020, using various staining techniques to analyze mucin presence and its association with specific cell types.
- Results indicated that mucin deposits were primarily found in hair follicles of follicular mucinosis cases and that CD8+ T cells had a significant role in mucin production compared to other cell types, suggesting different origins in mucin production between follicular and dermal forms of PCM.
Multiple skin-colored facial papules in a child.
JAAD Case Rep
September 2022
Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Successful treatment of follicular mucinosis with low-dose UVA1 phototherapy.
Dermatol Ther
October 2022
Department of Dermatology, Hospital Universitario San Cecilio, Granada, Spain.
Carbamazepine-induced follicular mucinosis-like drug eruption.
Indian J Dermatol Venereol Leprol
December 2022
Department of Dermatology, Shandong Provincial Hospital for Skin Disease & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, China.
Follicular mucinosis successfully treated by photodynamic therapy: Two case reports.
Photodiagnosis Photodyn Ther
September 2022
Department of Dermatology, Hangzhou Third People's Hospital; Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University; Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine; West Lake Road 38, Hangzhou 310009, PRChina. Electronic address:
Article Synopsis
- * The report discusses two patients—one with primary and one with secondary follicular mucinosis—who both showed great improvement after undergoing photodynamic therapy.
- * Follow-up biopsies indicated that the treatment's effectiveness correlated with a decrease in CD103, a marker for certain immune cells, suggesting changes in the pathology as the patients healed.
T-cell prolymphocytic leukemia with follicular mucinosis.
Int J Dermatol
March 2023
Department of Dermatology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Localized Follicular Mucinosis in a Child Treated Successfully with Pimecrolimus and Targeted Phototherapy.
Case Rep Dermatol
April 2022
Department of Dermatology, Deenanath Mangeshkar Hospital, Pune, India.
Article Synopsis
- - Follicular mucinosis (FM), also known as alopecia mucinosa, is a rare skin condition in children, with few case reports available.
- - A case study reports a 3-year-old child diagnosed with FM confirmed by histopathology.
- - The child's lesion successfully resolved using topical pimecrolimus cream and targeted phototherapy, with no recurrence noted afterwards.
Article Synopsis
- - A 68-year-old man was diagnosed with follicular mucinosis, a skin condition.
- - Dermoscopic examination revealed distinct features, including round brownish-yellow dots with whitish rims in hair follicles and red dots in the surrounding skin.
- - This case report is notable as it is the first to document these specific dermoscopic findings associated with follicular mucinosis.
A Case Report of Necrotizing Eosinophilic Folliculitis Occurring After Rhus Ingestion.
Clin Cosmet Investig Dermatol
February 2022
Department of Dermatology, College of Medicine, Chungbuk National University, Cheongju, Korea.
Article Synopsis
- Necrotizing eosinophilic folliculitis is a rare and more severe variant of eosinophilic folliculitis, characterized by necrotizing ulcerative symptoms.
- A case involving a 48-year-old man is described, where painful skin lesions developed after he consumed Rhus, leading to symptoms like facial swelling and intense itching.
- The patient's skin biopsy revealed significant eosinophil presence, and treatment with systemic steroids and dapsone effectively cleared the lesions, highlighting the need for clinicians to recognize this condition after Rhus exposure for timely treatment.
Follicular mucinosis with novel dermoscopic finding: the toothpaste sign.
Clin Exp Dermatol
May 2022
Department of Dermatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.
Article Synopsis
- - A case of follicular mucinosis was observed, resulting in patchy hair loss in the eyebrows.
- - Dermoscopy revealed a white, gelatinous substance alongside the hair shafts in the affected areas, which is thought to be mucin.
- - The authors suggest naming this unique dermoscopic feature the 'toothpaste sign.'