63 results match your criteria: "Allina Health Minneapolis Heart Institute[Affiliation]"

Transcatheter Edge-to-Edge Repair in Patients With Complex Tricuspid Valve Anatomy.

JACC Cardiovasc Interv

December 2024

University of Virginia, Charlottesville, Virginia, USA. Electronic address: https://twitter.com/psorajja.

Article Synopsis
  • Untreated severe tricuspid regurgitation (TR) is linked to poor health outcomes, making effective treatment essential.
  • The study evaluated the 1-year results of transcatheter edge-to-edge repair (TEER) using the TriClip system in patients with complex tricuspid valve issues, finding significant improvements in patient survival and quality of life.
  • Results showed that 81% of patients experienced a reduction in TR to moderate or less after one year, with no major adverse effects noted in the first 30 days post-procedure.
View Article and Find Full Text PDF

Despite the challenges associated with periprocedural imaging, transcatheter tricuspid valve interventions have shown important impact on outcomes. A comprehensive understanding of the anatomy of the right heart and surrounding structures is crucial. One way to optimize these interventions is by identifying the optimal fluoroscopic viewing angles along the S-curve of the tricuspid valve.

View Article and Find Full Text PDF
Article Synopsis
  • Peripartum cardiomyopathy (PPCM) poses serious health risks, and while recovery of heart function is important, it doesn't guarantee better long-term outcomes; additional assessments using cardiac MRI (CMR) can reveal further risks.
  • The study analyzed 51 PPCM patients, highlighting that lower left ventricular ejection fraction (LVEF), peak global longitudinal strain (GLS), and higher extracellular volume (ECV) were linked to worse outcomes, including the need for heart assist devices or transplants.
  • Findings suggest CMR might help identify patients at higher risk for serious adverse outcomes beyond what LVEF can indicate, potentially revealing future treatment targets like diffuse myocardial fibrosis.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on the impact of tricuspid regurgitation (TR) on heart remodeling, comparing outcomes in patients treated with the TriClip device versus those receiving standard medical therapy in a randomized controlled trial.
  • Researchers utilized advanced imaging techniques, including cardiac magnetic resonance and 4D-CT, to assess heart changes at baseline, 30 days, and one year follow-ups.
  • Results showed that the TriClip significantly reduced TR volume by 70% at 30 days, leading to notable reductions in right ventricular size and area, with these improvements maintained after one year, unlike the control group.
View Article and Find Full Text PDF

The Next Era of Quality Improvement: Owning the Challenge.

Circ Cardiovasc Qual Outcomes

November 2024

Cardiology Division, Department of Internal Medicine, O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas (S.R.D.).

View Article and Find Full Text PDF

Background: Lipoprotein (a) is an independent risk factor for atherosclerotic cardiovascular disease. However, lipoprotein (a) testing remains variable and it is unclear what factors influence testing and if testing changes clinical management.

Methods And Results: A retrospective study using electronic medical record data from 5 health systems identified an atherosclerotic cardiovascular disease cohort divided into those with and without a lipoprotein (a) test between 2019 and 2021.

View Article and Find Full Text PDF
Article Synopsis
  • - The TRILUMINATE Pivotal trial assessed the effects of tricuspid transcatheter edge-to-edge repair (T-TEER) on reducing tricuspid regurgitation (TR), a significant heart condition linked to increased health risks.
  • - Involving 572 patients, mostly elderly women with prior heart conditions, the trial found that T-TEER effectively improved quality of life, with nearly half of those treated experiencing significant improvements in heart health assessments.
  • - Results showed that while the treatment and control groups had similar rates of survival and heart-related surgeries, those who underwent T-TEER had notably better outcomes in TR severity and overall quality of life.
View Article and Find Full Text PDF

Background: Although guidelines recommend low-density lipoprotein cholesterol (LDL-C) to be < 70 mg/dL in patients with atherosclerotic cardiovascular disease (ASCVD), the rate of achieving this goal remains suboptimal. We sought to understand real world contemporary practice patterns of LDL-C management in patients with ASCVD, and whether LDL-C testing influenced management across US health systems.

Methods: A retrospective cohort study utilizing electronic medical record data from five health systems participating in the CardioHealth Alliance was performed on patients with an LDL-C measurement in 2021 and prior ASCVD.

View Article and Find Full Text PDF

Background: Transcarotid artery revascularization (TCAR) has emerged as an alternative therapeutic modality to carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TFCAS) for the management of patients with carotid artery stenosis. However, certain issues regarding the indications and contraindications of TCAR remain unanswered or unresolved. The aim of this international, expert-based Delphi consensus document was to attempt to provide some guidance on these topics.

View Article and Find Full Text PDF

Atrial Mechanics, Atrial Cardiomyopathy and Impact of Atrial Interventions.

J Card Fail

October 2024

Division of Cardiology, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Durham, NC, USA; Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland. Electronic address:

Article Synopsis
  • Our understanding of how the atria (upper chambers of the heart) work and how they can become dysfunctional (atrial cardiomyopathy) has improved, especially regarding their impact on various heart conditions.
  • Different atrial medical procedures can affect the way the atria function, and it's important for healthcare professionals to be aware of potential negative effects that may not show up right away.
  • By identifying early signs of atrial dysfunction, clinicians can intervene sooner, potentially preventing serious changes in atrial structure and function before they lead to visible health issues.
View Article and Find Full Text PDF
Article Synopsis
  • An interatrial shunt is being studied as a potential treatment for heart failure, aimed at lowering left atrial pressure and improving symptoms and outcomes for patients.
  • In a clinical trial involving 508 patients, participants were randomly assigned to receive either the shunt or a placebo, with their progress tracked over a maximum of two years.
  • Results showed that while the shunt had no major safety issues, it did not significantly improve overall effectiveness compared to the placebo, although it appeared to reduce adverse cardiovascular events in patients with reduced left ventricular ejection fraction.
View Article and Find Full Text PDF

Pericardial Diseases: International Position Statement on New Concepts and Advances in Multimodality Cardiac Imaging.

JACC Cardiovasc Imaging

August 2024

Department of Medicine, University of Udine, Udine, Italy; Cardiothoracic Department, University Hospital Santa Maria della Misericordia, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.

Pericardial diseases have gained renewed clinical interest, leading to a renaissance in the field. There have been many recent advances in pericardial diseases in both multimodality cardiac imaging of diagnoses, such as recurrent, transient constrictive and effusive-constrictive pericarditis, and targeted therapeutics, especially anti-interleukin (IL)-1 agents that affect the inflammasome as part of autoinflammatory pathophysiology. There remains a large educational gap for clinicians, leading to variability in evaluation and management of these patients.

View Article and Find Full Text PDF

Changing Context and Goals for Transcatheter Mitral Therapy.

JACC Cardiovasc Interv

July 2024

Valve Science Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA; Allina Health Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, Minnesota, USA. Electronic address:

View Article and Find Full Text PDF

Although current studies support the use of prophylactic distal perfusion catheters (DPCs) to decrease limb ischemia in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO), methods for monitoring limb ischemia differ between studies. We evaluated the safety of a selective rather than prophylactic DPC strategy at a single center with a well-established protocol for limb ischemia monitoring. Distal perfusion catheters were placed selectively if there was evidence of hypoperfusion at any point until decannulation.

View Article and Find Full Text PDF

The diagnostic approach toward the management of cardiac implantable electronic device-related tricuspid regurgitation is challenging and undefined. Functional cardiac computed tomography angiography provides a complementary role to echocardiography in the evaluation of lead-leaflet interaction which can help the clinical decision-making process, as presented in this case series.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focused on evaluating the safety and effectiveness of the APTURE transcatheter shunt system in patients with heart failure and left ventricular ejection fraction (LVEF) greater than 40%.
  • - Results showed that the APTURE shunt had a low incidence of serious complications (2.6%) and helped improve heart function, as indicated by reduced pulmonary capillary wedge pressure and improved quality of life scores over a year.
  • - Overall, the findings suggest that the APTURE shunt is a promising option for managing heart failure in patients with mildly reduced or preserved ejection fraction.
View Article and Find Full Text PDF
Article Synopsis
  • Surgical mitral valve repairs may not hold up over time, leading to potential repeat surgeries; transcatheter mitral valve-in-ring (MViR) offers a new option for high-risk patients.
  • A study analyzed outcomes of MViR involving 820 patients, with most in poor heart function classes and significant mitral regurgitation; initial results showed a 30-day mortality rate of 8.3% and a 1-year rate of 22.4%.
  • At one year, MViR patients experienced improvements in heart function and reduced mitral regurgitation, but there were concerns about elevated pressure gradients and a 9.1% reintervention rate, affirming MViR as a viable
View Article and Find Full Text PDF

Background: Inadequate inclusion in clinical trial enrollment may contribute to health inequities by evaluating interventions in cohorts that do not fully represent target populations.

Objectives: The aim of this study was to determine if characteristics of patients with heart failure (HF) enrolled in a pivotal trial are associated with who receives an intervention after approval.

Methods: Demographics from 2,017,107 Medicare patients hospitalized for HF were compared with those of the first 10,631 Medicare beneficiaries who received implantable pulmonary artery pressure sensors.

View Article and Find Full Text PDF

Aims: Despite increased temporary mechanical circulatory support (tMCS) utilization for acute myocardial infarction complicated by cardiogenic shock (AMI-CS), data regarding efficacy and optimal timing for tMCS support are limited. This study aimed to describe outcomes based on tMCS timing in AMI-CS and to identify predictors of 30-day mortality and readmission.

Methods And Results: Patients with AMI-CS identified in the National Readmissions Database were grouped according to the use of tMCS and early (<24 h) vs.

View Article and Find Full Text PDF

Self-Apposing Stents in Coronary Chronic Total Occlusions: A Pilot Study.

Heart Lung Circ

April 2024

Department of Cardiology, Aswan Heart Centre, Magdi Yacoub Global Heart Foundation, Aswan, Egypt.

Objectives: This pilot study assessed the 12-month angiographic and clinical outcomes of self-apposing (SA) stents in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Background: Self-apposing (SA) stents may decrease incomplete strut apposition and stent strut coverage that are common after CTO PCI.

Methods: We compared 20 patients who underwent CTO PCI using SA drug-eluting stents (DESs) with 20 matched control patients who underwent CTO PCI using balloon-expandable (BE)-DESs.

View Article and Find Full Text PDF