Global Assessment of Training Needs in Addiction Medicine.

Introduction: A minority of addiction patients receive appropriate treatment directly from trained professionals in addiction medicine. Most countries have not recognized addiction medicine (AM) as a specialty in its own right or within psychiatry/other specialties. Therefore, the effectiveness and organization of AM training around the world need to be improved.

Evaluating the Sealing Performance of Endodontic Sealers: Insights Into Achieving Complete Sealing.

Background The importance of achieving optimal sealing in endodontic procedures cannot be overstated, as it directly influences the success and durability of root canal treatments. The objective of this research was to measure and identify the sealing ability of endodontic sealers by evaluating their adhesion to root canal dentin and the extent to which they achieve a complete seal. Methods A total of 60 extracted lower premolar teeth were randomly divided into three groups of 20 samples each.

An Observational Case-control Study for BDNF Val66Met Polymorphism and Serum BDNF in Patients with Major Depressive Disorder (MDD).

Background: The brain-derived neurotrophic factor (BDNF) has an important role in the growth of neurons and synaptic transmission. The BDNF gene Val66Met polymorphism (G/A) is associated with depression, but findings have not been consistently replicated. This study adopts a case-control design with an aim to investigate the association of Val66Met polymorphism and peripheral BDNF (serum) levels in patients of major depressive disorder (MDD) and healthy individuals (controls).

Cariprazine-Induced Extrapyramidal Symptoms and a Rare Downward Eye Deviation in Oculogyric Crisis: A Case Series.

Cariprazine is one of the newer generation antipsychotics with dopamine receptor partial agonist activity which has been approved for management of schizophrenia and bipolar affective disorder. It is known to have lesser propensity to cause extrapyramidal adverse effects due to D2 and D3 partial agonism. We intend to disseminate our newly acquired experience regarding tolerability and the adverse effect profile of cariprazine.

Efficacy of Theta Burst Stimulation in Bipolar Depression: A Systematic Review and Meta-analysis.

Purpose: Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising alternative therapeutic modality for bipolar depression. Theta Burst Stimulation (TBS) a novel variant of rTMS is currently evolving as an effective and safe therapeutic tool in the management of bipolar depression, although it is still in the initial phase. In the present systematic review and meta-analysis, data from various studies investigating the effectiveness and tolerability of TBS in individuals with bipolar depression were synthesized.

Translation, Cultural Adaptation, and Psychometric Properties of Hindi Rosenberg Self-esteem Scale in University Nursing Students.

Background: Rosenberg's Self-esteem Scale (RSES) has been widely used without proper translation, cultural adaptation, and testing psychometric properties in Indian studies. The study aimed to translate and culturally adapt the 10-item Rosenberg Self-esteem Scale into Hindi and find psychometric properties.

Material And Methods: We have translated the scale using World Health Organization (WHO) guidelines.

Mapping the Geographic Inequalities in Psychiatrist Distribution across Madhya Pradesh, India: An Exploratory Study.

Objective: The National Mental Health Survey identified a vast treatment gap across India. This treatment gap is partly attributed to the availability and accessibility of mental health services in different states. Accessibility to a psychiatrist in Madhya Pradesh (MP) is essential due to the significant disparity among urban, rural, and tribal regions across the state.

Obesity Awareness and Sensitization in Schools for Improving Weight Control and Reducing Obesity Stigma in Students: A Pilot Study.

Introduction: The prevalence of obesity is increasing rapidly in the world, including India. Since obesity is a risk factor for many diseases, the prevalence of obesity-related diseases is also increasing, resulting in decreased productivity and increased disease-related expenses, causing economic loss at the individual, family, and national levels. Government funds that could be utilized for national growth are channeled into the treatment of non-communicable diseases (NCDs).

Research Methodology and Biostatistics in the Postgraduate Curriculum: The AIIMS-Bhubaneswar Experience.

Inclusion of research methodology and biostatistics in the postgraduate curriculum by the National Medical Commission is a welcome step to improve the research milieu in medical colleges in India. This step will have a long-term impact on research outcomes and scientific publications. In 2019, AIIMS-Bhubaneswar implemented the revised postgraduate curriculum, which introduced a faculty-facilitated program on research methodology and biostatistics for all postgraduate students.

A comparison of clinical and radiological outcomes following laminectomy and laminectomy with fusion in patients of cervical spondylotic myelopathy: A systematic review and meta-analysis.

To conduct a systematic review and meta-analysis comparing the functional and radiological outcomes in cervical spondylotic myelopathy (CSM) when treated by Laminectomy (LC) vs. laminectomy with instrumented fusion (LCF). The systematic review was conducted in accordance with PRISMA guidelines.

Plasma Cell Gingivitis With Plasma Cell Cheilitis: A Diagnostic Challenge.

Plasma cell gingivitis and cheilitis are diagnostic challenges for dental practitioners. To the best of the authors' knowledge, concomitant plasma cell gingivitis and plasma cell cheilitis in the same patient has not been reported in the dental literature, although these conditions have been reported separately (on lips and gingiva) several times. Underreporting of these coexisting clinical conditions may be attributed to a lack of awareness of both conditions and underperformance of comprehensive histopathological examinations.

Multisystem inflammatory syndrome in adults hospitalizations in the United States; evaluating patient characteristics, COVID-19 associations, and mortality.

Introduction: Multisystem inflammatory syndrome in adults (MIS-A) is thought to be closely linked with COVID-19 infection. This study aims to elucidate the demographics and clinical characteristics of MIS-A, aiding in timely diagnosis and management.

Methods: Utilizing the National Inpatient Sample (NIS) database (2021), patients were stratified into MIS-A and non-MIS-A groups.

When a Child has Neck Mass, Consider a Choristoma too! Here's a Rare Instance: A Cervical Chondrocutaneous Branchial Remnant.

Cervical chondrocutaneous branchial remnants (CCBR) are rare causes of neck masses in young children. It is commonly associated with genitourinary and cardiac anomalies. We report a case of CCBR in a two-year-old male child who presented with a unilateral painless pedunculated neck mass.

Generation of Functional Neurons from Mesenchymal Stem Cells Using Neural Differentiator and Engineered Peptide Hydrogel: Potential Therapeutic Lead for Traumatic Brain Injury.

Traumatic brain injuries (TBIs) cause multifaceted disruption in the neural network, initiate huge inflammation processes, and form glial scars that result in severe damage to the brain. Thus, the treatment of TBI is a challenging task. To address this challenge, a newer and innovative approach is extremely important to develop a successful therapeutic strategy.

Utility of shear wave elastography in evaluation of children with chronic kidney disease.

Background: Shear wave elastography (SWE) is proven for liver fibrosis. However, there are challenges in assessing the kidney owing to its surrounding structures, retroperitoneal location, and visceral fat. Kidney biopsy is the gold standard for estimating fibrosis, but is associated with inherent risks of bleeding and sedation.

Outcomes and complications of hip arthroscopy for femoroacetabular impingement syndrome: A narrative review.

Hip arthroscopy has emerged as the primary surgical intervention for Femoroacetabular Impingement Syndrome (FAIS), a common cause of hip pain in young adults, particularly athletes. This narrative review examines the long-term outcomes, complications, and debates surrounding arthroscopic management of FAIS. Key findings include sustained improvements in patient-reported outcomes, return to sport, and functional recovery, particularly in younger patients and those with cam-type FAIS.