Implementing Lifestyle Medicine Competencies in Didactic and Clinical Settings for Allied Health Professionals: A Call to Action.

In this article, we discuss and reflect on the essential components of our concurrent session presentation at the American College of Lifestyle Medicine (ACLM) annual conference LM2023, "Implementing Lifestyle Medicine Competencies in Didactic and Clinical Settings for Allied Health Professionals." We illustrate the necessity of interdisciplinary lifestyle medicine approaches through a conscious fusion of analysis and storytelling. This review concludes with a call to action empowering the medical community to embrace interdisciplinary lifestyle medicine approaches in effort to increase access to equitable healthcare.

PPROM in the late preterm period: an argument for expectant management.

Preterm prelabor rupture of membranes (PPROM) is associated with significant neonatal risks. When PPROM occurs during the late preterm period (between 34 0/7 and 36 6/7 weeks gestation), the optimal gestational age for delivery is unclear and varies by regional practice. In 2020 the American College of Obstetrician and Gynecologists (ACOG) published guidelines indicating that both expectant management and immediate delivery were considered reasonable options.

Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments.

Trastuzumab (TZM) is a monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2) and is clinically used for the treatment of HER2-positive breast tumors. However, the tumor microenvironment can limit the access of TZM to the HER2 targets across the whole tumor and thereby compromising TZM's therapeutic efficacy. An imaging methodology that can non-invasively quantify the binding of TZM-HER2, which is required for therapeutic action, and distribution within tumors with varying tumor microenvironments is much needed.

Post-Operative Urinary Tract Infections After Radical Cystectomy: Incidence, Pathogens, and Risk Factors.

: The incidence of urinary tract infections (UTIs) after radical cystectomy (RC) with urinary diversion (UD), the typical pathogens, and associated patient risk factors have not been well documented. In this study, we examined the incidence of post-op UTIs after RC to identify associated risk factors. : Single-center, retrospective case series of 386 patients with bladder cancer who underwent RC with UD between 2012 and 2024.

Nanoparticle-Mediated Delivery of Deferasirox: A Promising Strategy Against Invasive Aspergillosis.

Background: Invasive aspergillosis (IA) is a deadly fungal lung infection. Antifungal resistance and treatment side effects are major concerns. Iron chelators are vital for IA management, but systemic use can cause side effects.

Long-term Outcomes of a Modified Straight-line Palate Repair Technique: Low Speech Correcting Surgery and Fistula Rates.

Background: The goal of cleft palate (CP) repair is to restore normal speech, however, rates of velopharyngeal insufficiency (VPI) after palatoplasty remain high. We present a modified straight-line palate repair (SLR) technique that facilitates velum length to alleviate VPI. The technique releases nasal mucosa with the levator muscle off the hard palate.

Pan-cancer analysis identifies the oncogenic role of in human cancers.

Objective: To investigate expression, prognosis, immune cell infiltration of C () in cancer.

Methods: We used TIMER and GEPIA datasets to analyze the differential expression of in multiple tumors. GEPIA and Kaplan-Meier plotter databases were utilized to observe the prognostic significance of in cancer.

Rapamycin improves satellite cells' autophagy and muscle regeneration during hypercapnia.

Both CO2 retention, or hypercapnia, and skeletal muscle dysfunction predict higher mortality in critically ill patients. Mechanistically, muscle injury and reduced myogenesis contribute to critical illness myopathy, and while hypercapnia causes muscle wasting, no research has been conducted on hypercapnia-driven dysfunctional myogenesis in vivo. Autophagy flux regulates myogenesis by supporting skeletal muscle stem cell - satellite cell - activation, and previous data suggest that hypercapnia inhibits autophagy.

Large Language Models to Identify Advance Care Planning in Patients With Advanced Cancer.

Context: Efficiently tracking Advance Care Planning (ACP) documentation in electronic heath records (EHRs) is essential for quality improvement and research efforts. The use of large language models (LLMs) offers a novel approach to this task.

Objectives: To evaluate the ability of LLMs to identify ACP in EHRs for patients with advanced cancer and compare performance to gold-standard manual chart review and natural language processing (NLP).

American College of Medical Genetics and Genomics ACT Sheets Are a Vital Resource for State Newborn Screening Programs.

The American College of Medical Genetics and Genomics (ACMG) and the National Coordinating Center for the Regional Genetics Networks (NCC)-developed ACT sheets are a vital resource for state newborn screening (NBS) programs. They allow NBS programs to be able to provide up-to-date, just-in-time disorder information to primary care providers (PCPs). Their continued availability is necessary to ensure that all babies identified by newborn screening receive appropriate evaluation and care.

Achievement of the patient acceptable symptom state following total shoulder arthroplasty with nonspherical humeral head and inlay glenoid.

Background: Total shoulder arthroplasty (TSA) with a nonspherical humeral head component and inlay glenoid is a bone preserving treatment for glenohumeral arthritis. This study aims to describe minimum two year patient reported outcomes, patient acceptable symptomatic state (PASS) achievement, and complications following TSA with this prosthesis.

Methods: A retrospective review of patients undergoing TSA with nonspherical humeral head and inlay glenoid was performed.

Anti-obesity and other health benefits of bioprocessed black rice bran in combination with green tea extract in 3T3-L1 preadipocyte cells and in mice on a high-fat diet.

Black rice bran, a waste product from the commercial milling of black rice that removes the bran and germ leaving the starchy endosperm, contains bioactive anthocyanin, phenolic, and phytosteroid compounds that may have health benefits. This study determined the effect of a polysaccharide-rich bioprocessed (fermented) black rice bran and a green tea extract individually and in combination on weight loss in orally fed mice on a high-fat diet and on concurrent changes in blood glucose and insulin as well as in cholesterol, triglyceride, and high-density and low-density lipoproteins (HDL and LDL). At the end of the eight-week feeding study, the combination diet resulted in a 67% lower weight gain than mice on a high-fat diet alone, a greater effect than that of bioprocessed black rice bran or green tea extract individually.

Flu-Phobia: Influenza Vaccine Hesitancy in a Rural Primary Care Setting.

The sentiments expressed by individuals, such as "I do not trust vaccines," "I do not believe in vaccines," and "I do not want a shot," are commonly encountered by physicians during the annual influenza season. This study investigates vaccine hesitancy regarding the influenza vaccine within a rural primary care setting in New York State. Observations of subjective comments from community members prompted an inquiry into whether the contentious discourse surrounding the COVID-19 vaccine has influenced patients' decisions about the influenza vaccination.

Adjunctive Middle Meningeal Artery Embolization for Subdural Hematoma.

Background: Subacute and chronic subdural hematomas are common and frequently recur after surgical evacuation. The effect of adjunctive middle meningeal artery embolization on the risk of reoperation remains unclear.

Methods: In a prospective, multicenter, interventional, adaptive-design trial, we randomly assigned patients with symptomatic subacute or chronic subdural hematoma with an indication for surgical evacuation to undergo middle meningeal artery embolization plus surgery (treatment group) or surgery alone (control group).

Operative complications of open and minimally invasive adnexal surgery compared with cases with hysterectomy: A narrative review.

The decision to add hysterectomy to planned adnexectomy is often nuanced and likely increases the complexity of the planned procedure; however, these risks are not well characterized in practice. We conducted a comprehensive search in the PubMed database for English-language articles from 1997 to 2022, identifying studies reporting complication rates for open and minimally invasive surgery (MIS) hysterectomy and adnexal surgeries. We calculated medians and first and third quartiles for each complication and used a Mann-Whitney U test to calculate differences between complications for minimally invasive hysterectomy and adnexal case data.

Moving Toward an Online Thematic Apperception Test (TAT): The Impact of Administration Modifications on Narrative Length and Story Richness.

The Thematic Apperception Test (TAT) is the second most commonly used performance-based task. However, traditional TAT administration is time-consuming and raises accessibility issues. Research exploring administration modifications has found that within a lab setting, having participants type their own narratives leads to richer responses than when participants narrate the stories out loud to an examiner.

The Effect of Medicaid Expansion on Access to Anti-incontinence Surgery.

Importance: Medicaid expansion broadened access to care; however, limited data about the effect on access to anti-incontinence surgical procedures exist.

Objective: Since the Affordable Care Act (ACA) Medicaid expansion in 2014, some regions have had more states adopt expansion (NE-Northeast, W-West) than other regions (S-South, MW-Midwest). We aimed to determine if the proportion of Medicaid funded anti-incontinence procedures increased after Medicaid expansion and whether increases were different by U.

Premaxillary Setback in the Management of Patients With Bilateral Cleft Lip: A 2 Decade Review.

Objective: This study analyzes indications and outcomes of premaxillary setback (PS) and presents an algorithm for its use in patients with bilateral cleft lip and/or palate (BCL ± P).

Design: Retrospective review.

Setting: Children's Hospital Los Angeles.