Role of nitric oxide in urinary bladder function: effect of L-arginine.

Background: Evidence indicates that decreased blood flow to the bladder plays a major role in obstructive bladder dysfunction in the rabbit model of partial bladder outlet obstruction (PBOO), and that nitric oxide (NO) regulation of blood flow may be important in modulating the degree of obstructive bladder dysfunction. The specific aim of our study is to determine the effect of feeding rabbits a diet high in L-arginine on the response to PBOO.

Materials And Methods: Sixteen male NZ White rabbits were separated into 4 groups of 4 each.