469 results match your criteria: "AlZahra Hospital[Affiliation]"

Background: Cancer development is aided by the role of long noncoding RNAs (lncRNAs) that act as competing endogenous RNAs (ceRNAs) absorbing microRNAs (miRNAs). We aimed to discover a novel regulatory axis in colorectal cancer (CRC) and potential biomarkers based on miR-616-3p.

Materials And Methods: The gene expression omnibus database was mined for differentially expressed lncRNAs (DELs) and mRNAs.

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Article Synopsis
  • - The study analyzed stool samples from colorectal cancer patients to compare hotspot mutations between Iranian and Finnish populations.
  • - The Iranian group had 35 distinct mutations, while the Finnish group showed 13 mutations; some mutations were unique to each cohort.
  • - Higher mutation frequencies were found in genes related to MAPK and PI3K-MAPK pathways in the Iranian cohort, suggesting potential implications for treatment strategies.
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We investigated the relationship between dietary phytochemical index (DPI) and migraine headaches in Iranian patients, analyzing both clinical and psychological traits. A cross-sectional study was conducted using non-obese adults aged 20-50 years who were diagnosed with migraine. The study used a validated 168-item food frequency questionnaire to assess the usual dietary intake of participants.

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Background: Pregnant women's knowledge about labor analgesia and the acceptance rate of this method are still undesirable in developing countries.

Objectives: This study aimed to examine pregnant women's knowledge, attitude, and acceptance of painless labor.

Methods: The present observational study was conducted in a referral university hospital in Northern Iran from September 2022 to April 2023.

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Aims: In this study, we aimed to evaluate the relationship between the dietary inflammatory index (DII) and mental health outcomes among patients with migraine headaches.

Methods: In this cross-sectional study, 262 subjects were included. The dietary intakes were collected using a validated 168-item semi-quantitative food frequency questionnaire.

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Despite the benefits of spinal anesthesia and the preference of anesthesiologists for this technique, it is less accepted by urologists due to the proximity of the stone place in the ureter and the possibility of pain, restlessness, and occasional movements of the patient during surgery. The current study investigated the success of bupivacaine plus intrathecal fentanyl in patients undergoing transurethral lithotripsy (TUL). In this randomized clinical trial, from April 2021 to September 2021, 54 patients with proximal urolithiasis candidates for TUL were enrolled.

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Aims: There is a paucity of evidence regarding the benefit of royal jelly (RJ) on post-stroke complications in patients with ischemic stroke. To address this knowledge gap, this randomized, triple-blind, placebo-controlled clinical trial was carried out to determine the effects of RJ consumption on post-stroke clinical outcomes.

Methods: Of 64 eligible ischemic stroke patients (45-80 years), 32 were randomized to the RJ and 32 to the placebo groups and completed a 12-week intervention.

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Objective: To examine the contribution of preterm birth and size-for-gestational age in stillbirths using six 'newborn types'.

Design: Population-based multi-country analyses.

Setting: Births collected through routine data systems in 13 countries.

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Cerebrovascular diseases comprise a significant portion of neurological disorders related to coronavirus disease 2019 (COVID-19). We evaluated the clinical and imaging characteristics of a cohort of COVID-19 patients with stroke and also identified patients with watershed infarcts. In this cross-sectional study, seventy-three COVID-19 patients with ischemic stroke were included between October 2020 and January 2021.

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Advances in human reproductive biomarkers.

Clin Chim Acta

January 2024

Division of Pharmacology and toxicology Department of Basic Sciences, Faculty of Veterinary Medicine University of Tabriz, Tabriz, Iran.

Reproductive biomarkers are important regulators in women, especially during pregnancy and childbirth. Because of their essential role in women's health, the discovery and quantification of reproductive biomarkers is of great clinical importance. Nowadays, there are many detection strategies to detect these biomarkers, including VEGF, human chorionic gonadotropin (hCG), etc.

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Introduction: The reciprocation between systemic inflammatory markers (SIMs), dyslipidemia, and hot flashes (HFs) can play a part in the pathogenesis of endothelial dysfunction through menopause. This study intended to determine the association between some SIMs, lipids, and HFs in healthy menopausal women.

Materials And Methods: We designed a cross-sectional study in which 160 healthy menopausal women aged 40-60 were enrolled.

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Background: Coronavirus disease 2019 (COVID-19) was detected in the throat, urine, and feces but has little evidence documented of sexual transmission.

Objective: Here, we aimed to diagnose the presence of COVID-19 in vaginal fluids and menses blood. Menstrual cycle duration and sexual desire were the other aims.

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Development of preeclampsia in pregnant women with white-coat hypertension: a systematic review and meta-analysis.

Arch Gynecol Obstet

March 2024

Women Reproductive Health Research Center, Tabriz University of Medical Sciences, Alzahra Hospital, South Artesh St., Tabriz, Iran.

Objective: Hypertensive disorders during pregnancy are a significant cause of maternal and perinatal mortality and morbidity worldwide. White coat hypertension (WCH) is a hypertensive disease characterized by an increased clinic blood pressure but normal home or workplace blood pressure. Due to variable prevalence, a subset of women with WCH may be incorrectly diagnosed with chronic hypertension, highlighting the need for accurate diagnosis.

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Background: Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication of infertility treatment. Vulvar edema is a disease with various causes and frequent phenomena seen in physiological and pathologic conditions like pregnancy, inflammatory disorders, tumors, idiopathic reasons, and most importantly, in the severe form of OHSS.

Case Presentation: Here, we report a 26-yr-old woman with severe OHSS, recombinant follicle-stimulating hormone therapy.

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Background: Poor sleep quality is a common issue among patients with end-stage renal disease (ESRD) who undergo dialysis. Nutritional habits are associated with sleep hygiene in patients undergoing dialysis. The objective of this study was to examine the potential correlation between nutritional status and sleep quality in individuals receiving hemodialysis treatment.

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Hydatid cyst is a common disease between humans and animals. Foods that are contaminated with eggs of echinococcal species are the cause of hydatid disease. Although this parasite affects different organs, the liver and lungs are very susceptible but the cardiac hydatid disease is very rare.

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Background And Aims: Ectopic pregnancy (EP) is a potentially life-threatening emergency. We investigate the predictive value of serum βHCG level and it's changes from the baseline to the 4th and 7th days after single dose (SD) methotrexate (MTX) treatment in successful treatment of tubal EP. It is important for early diagnosis of EP.

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Aims: There is limited evidence on the link between diet quality and migraine headaches. The present study aimed to evaluate the association between dietary diversity score (DDS), as a good representative of overall diet quality, and clinical features of migraine headaches.

Methods: In total, 262 subjects (224 females and 34 males), aged 20 to 50  years old were included in the present cross-sectional study.

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Background: Infants undergo extremely painful procedures in a Neonatal Intensive Care Unit (NICU), which if left uncontrolled may cause complications. Therefore, this study was conducted to investigate gentle touch effect on cardiorespiratory indices and pain behaviors related to venipuncture and blood sampling in preterm infants.

Materials And Methods: A quasi-experimental study was undertaken in gentle touch and control groups in three stages.

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Aims: We evaluated associations between diet quality and migraine outcomes.

Methods: The current work represented a cross-sectional study on 262 patients with migraine (20-50 y). Diet quality was assessed using the standard healthy eating index 2015 (HEI-2015) and alternative healthy eating index 2010 (AHEI-2010).

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Mutational landscape of phenylketonuria in Iran.

J Cell Mol Med

September 2023

Department of Medical Genetics and Molecular Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

To date more than 1000 different variants in the PAH gene have been identified in patients with phenylketonuria (PKU). In Iran, several studies have been performed to investigate the genetics bases of the PKU in different parts of the country. In this study, we have analysed and present an update of the mutational landscape of the PAH gene as well as the population genetics and frequencies of detected variants for each cohort.

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Aims: The present study was conducted among Iranian individuals diagnosed with migraine headaches to investigate the association between plant-based eating patterns and the clinical features of a migraine headache.

Methods: In total, 262 patients aged 20-50 years who were diagnosed with migraine headaches were included in the current cross-sectional study. Participants' dietary intake was assessed using a validated 168-item, semi-quantitative food frequency questionnaire (FFQ).

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Article Synopsis
  • - The study investigated the outcomes of abdominal aortic aneurysm (AAA) repair surgeries, comparing open surgery with endovascular repair methods in 60 patients at Razi Hospital from 2010 to 2019.
  • - Results showed that patients who underwent endovascular repair had significantly lower rates of complications, shorter hospital stays, and reduced need for pain management compared to those who had open surgery.
  • - The conclusion highlighted that endovascular surgery is safer with fewer postoperative complications and in-hospital deaths than traditional open surgery for AAA repair.
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Objectives: Rhinoplasty is one of the most common cosmetic surgeries in the world. Lack of adequate local homeostasis may lead to excessive bleeding during the operation, which increases the time of operation and recovery period, and the prevalence of complications. This study investigated the effects of nasal desmopressin on the quality of the surgical field and the volume of bleeding during rhinoplasty.

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Background: Diastolic dysfunction (DD) is a risk factor for cardiovascular events in patients undergoing non-cardiac surgeries. Investigators aimed to assess the effect of physical activity level on the diastolic function of the left ventricle (LV) in patients attending the preoperative visit.

Methods: This analytic cross-sectional study was conducted on 228 patients referred to Poursina hospital from November 2021 to March 2022.

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