Theoretical Sensing Performance for Detection of Cyclophosphamide Drug by Using Aluminum Carbide (CAl) Monolayer: a DFT Study.

Because nanomaterials are highly reactive and electronically sensitive towards a variety of drug molecules, they are thought of as efficient drug sensors. In the present research study, an aluminum carbide (CAl) monolayer is employed and its interaction is examined with cyclophosphamide (CP) by performing DFT computations. The CAl monolayer is highly reactive and sensitive towards CP according to the computations.

Application of zinc oxide nano-tube as drug-delivery vehicles of anticancer drug.

Context: Zinc oxide nano-tube (ZnONT) nano-structures, which possess chemical stability and non-toxicity in the human body, are considered promising for delivering different drugs. Within this work, we scrutinized the drug delivery capability of the ZnONT and its adsorptional properties as a drug delivery vehicle (DDV) for hydroxyurea (HU) as an anti-cancer drug through density functional theory along with the solvent impacts. Based on the optimized structures, it can be suggested that Zn atoms of ZnONT are the ideal sites on this nano-tube for the adsorption of HU.

Ovine Pasteurellosis Vaccine: Assessment of the Protective Antibody Titer and Recognition of the Prevailing Serotypes.

Sheep husbandry is considered one of the most important activities in the socio-economic development in the Middle East region, especially in Iraq and Islamic Republic of Iran (IRI). Therefore this study was designed to evaluate the level of ovine pasteurellosis vaccine protective antibody titer and identification of the prevailing serotypes in Iraq (Basrah, Baghdad, Tikrit, Mosul, Erbil). The vaccine was made from Bio-type A and the serotypes of .

The Potential Benefits of Legumes Germ and Cereal Grains on Roosters' Reproductive Performance.

Vit E is known as one of the most important antioxidant. It has been previously approved that cereal grains and leafy plants are considered as the main source for α-tocopherol (Vit E). One of the recommended therapies for male infertility would be the Vit E therapy.

The Influence of Rumen-Protected Choline and α-tocopherol Supplementation on Early Lactating Dairy Cows Metabolism.

It is well documented that choline is known as one of the essential ingredients of phospholipids. Choline acts as a determinative element for appropriate cell membrane functions. On the other hand α-tocopherol (Vit E) is a fat-soluble vitamin.

Analysis of the protection of copper corrosion by using amino acid inhibitors.

Since the human body is one of the highly aggressive environments, the materials utilized for an implant should have high resistance to degradation and corrosion. One of the commonly used biomaterials in medicine is copper (Cu). The Cu corrosion can result in the release of ions in the body with high toxicity, thereby causing inflammatory diseases.

BeO nanotube as a promising material for anticancer drugs delivery system.

In this research, the application of BeO nanotube (BeONT) as a nanocarrier for Fluorouracil (5-FU) anticancer drug has been studied by density functional theory (DFT) approach. The method B97XD with 6-31 G** basis set were employed. A precise surface study, shows that there are two directions for 5-FU adsorption that did not deliver any of the imaginary frequency vibrational spectra, identifying that all relaxation structures are at the lowest energy level.

Identify Biomarkers and Design Effective Multi-Target Drugs in Ovarian Cancer: Hit Network-Target Sets Model Optimizing.

Epithelial ovarian cancer (EOC) is highly aggressive with poor patient outcomes, and a deeper understanding of ovarian cancer tumorigenesis could help guide future treatment development. We proposed an optimized hit network-target sets model to systematically characterize the underlying pathological mechanisms and intra-tumoral heterogeneity in human ovarian cancer. Using TCGA data, we constructed an epithelial ovarian cancer regulatory network in this study.

Circulating and dietary advanced glycation end products and obesity in an adult population: A paradox of their detrimental effects in obesity.

Background: The detrimental role of advanced glycation end products (AGEs) against cardio-metabolic health has been revealed in several previous reports. However, the results of studies regarding the association between AGEs and obesity measurements are inconsistent. In the current meta-analysis, we aimed to quantitatively summarize the results of studies that evaluated the association between circulating and dietary AGEs with obesity measurements among the adult population.

Direct selenosulfonylation of unsaturated compounds: a review.

In this review, we have discussed recent developments on the direct selenosulfonylation of unsaturated compounds which lead to the formation of two new carbon-sulfur and carbon-selenium bonds in a single operation. The reactions were classified based on the type of starting unsaturated compound and product. Thus, the review is divided into three major sections.

Recent advances in atezolizumab-based programmed death-ligand 1 (PD-L1) blockade therapy for breast cancer.

Breast cancer, the most common cancer in women worldwide, is curable in ∼ 70-80 % of patients with early-stage, non-metastatic disorder. However, advanced breast cancer with distant organ metastases is incurable with available therapeutics. Thus, scientists have sought emerging strategies for treating metastatic breast cancers.

Ketoprofen suppresses triple negative breast cancer cell growth by inducing apoptosis and inhibiting autophagy.

Background: Triple-negative breast cancer (TNBC) is an invasive phenotype with undesirable clinical features, poor prognosis, and therapy resistance. Ketoprofen is a Non-steroidal anti-inflammatory drug (NSAID) with anti-tumor properties.

Aim: To investigate the effects of Ketoprofen on apoptosis and autophagy in TNBC cell line MDA-MB-231.

Adsorption of Thiotepa anticancer drugs on the BC nanotube as a promising nanocarriers for drug delivery.

By applying periodic DFT computations, the possible employment of BC nanotube (BCNT) as a drug delivery system (DDS) for Thiotepa (TPA) anticancer medicine has been examined. Quantum mechanics computations by the B3LYP-6-31 +G(d,p) method with dispersion correction including to be used for calculation the details of electronic, geometric, and energetic features of the interactions between TPA drug and BCNT. The appropriate orientation for the TPA interacting with BCNT has been assessed and adsorption energies (ΔE) have been computed.

Isolation insult during COVID-19 pandemic on the psychological status of medical students.

Background: COVID-19 is a newly discovered infectious disease that spread and caused a global health problem. Medical students, especially those in clinical stages are among groups exposed to the disease. The study aimed to show the impact of social distancing on the mental health of Iraqi medical students.

Intrapartum cardiotocography trace pattern pre-processing, features extraction and fetal health condition diagnoses based on RCOG guideline.

Context: The computerization of both fetal heart rate (FHR) and intelligent classification modeling of the cardiotocograph (CTG) is one of the approaches that are utilized in assisting obstetricians in conducting initial interpretation based on (CTG) analysis. CTG tracing interpretation is crucial for the monitoring of the fetal status during weeks into the pregnancy and childbirth. Most contemporary studies rely on computer-assisted fetal heart rate (FHR) feature extraction and CTG categorization to determine the best precise diagnosis for tracking fetal health during pregnancy.

Regulation of Nrf2 and Nrf2-related proteins by ganoderma lucidum ın hepatocellular carcinoma.

Background: HCC is among the most common cancer. Ganoderma lucidum (G.lucidum) has been essential in preventing and treating cancer.

Deep Sentiment Analysis of Twitter Data Using a Hybrid Ghost Convolution Neural Network Model.

Several problems remain, despite the evident advantages of sentiment analysis of public opinion represented on Twitter and Facebook. On complicated training data, hybrid approaches may reduce sentiment mistakes. This research assesses the dependability of numerous hybrid approaches on a variety of datasets.

lncRNA-miRNA-mRNA ceRNA Network Involved in Sheep Prolificacy: An Integrated Approach.

Understanding the molecular pattern of fertility is considered as an important step in breeding of different species, and despite the high importance of the fertility, little success has been achieved in dissecting the interactome basis of sheep fertility. However, the complex mechanisms associated with prolificacy in sheep have not been fully understood. Therefore, this study aimed to use competitive endogenous RNA (ceRNA) networks to evaluate this trait to better understand the molecular mechanisms responsible for fertility.

The Practices of Solid Waste Utility and Thriving Conditions of Logistics (a Case of Tepi Town): A Study to Treat the Healthy Environment.

Unwanted remains, discarded residues, and byproduct materials that are not required by the initial user are known as wastes. In Ethiopia, improper solid waste management becomes endemic and it affects the health conditions, comforts, and freedom of town communities. Improper solid waste management can also adversely affect infrastructure damages, socioeconomic conditions, and environmental and health problems.

Assessing Deep Learning Techniques for the Recognition of Tropical Disease in Images from Parasitological Exams.

is one of the tropical diseases with the greatest epidemic reach in the world. One of the WHO guidelines is the prior and efficient diagnosis for mapping foci and applying the appropriate treatment of infected people. The current process for diagnosis still depends on an analysis of parasitological exams performed by a human being under a laboratory microscope.

ASSESSMENT OF INTERNS' TRAINING IN THE TEACHING HOSPITALS OF BAGHDAD MEDICAL CITY COMPLEX.

Objective: The aim: The aim of this study is to assess the training of medical interns in Baghdad Medical City Complex.

Patients And Methods: Materials and methods: A cross-sectional observational study was conducted in the Medical City Complex, Baghdad. The study targeted all the medical interns who finished year one of internship.

PRETERM DETECTION OF CONGENITAL ANOMALIES BY ULTRASOUND AND CORRELATION WITH POSSIBLE ASSOCIATED RISK FACTORS.

Objective: The aim: This descriptive, cross-sectional study aims to determine the prevalence of congenital anomalies in the Iraqi population, the associated risk factors & to emphasize the importance of ultrasound examination during pregnancy especially in the high-risk group.

Patients And Methods: Materials and methods: Data were collected from three private ultrasound clinics in different areas in Baghdad, where many pregnant women were examined over one year and those who had abnormal fetus were questioned about any possible risk factor.

Results: Results: The study revealed a prevalence of (14/1000).

FACTORS ASSOCIATED WITH ANEMIA IN WOMEN OF REPRODUCTIVE AGE IN IRAQI FEMALES SAMPLE.

Objective: The aim of this study: to determine the different causes of anemia among anemic women of reproductive age and to define associations between severity of anemia with different patient characteristics.

Patients And Methods: Materials and methods: This is a community based cross-sectional study that was conducted between October and December 2020 among a sample of anemic women at reproductive age between (14-49 years), who attended the private clinic in Baghdad city. The sample consisted of 120 participants (100 non-pregnant women and 20 pregnant women).

Remotely Monitoring COVID-19 Patient Health Condition Using Metaheuristics Convolute Networks from IoT-Based Wearable Device Health Data.

Today, COVID-19-patient health monitoring and management are major public health challenges for technologies. This research monitored COVID-19 patients by using the Internet of Things. IoT-based collected real-time GPS helps alert the patient automatically to reduce risk factors.