Sirtuin 1 Expression Enhances the Inflammatory Response in Allergic Rhinitis Combined with Asthma.

Asthma (ASTH) is a chronic inflammatory disease that affects the lung airway and leads to occasional breathing difficulties. Previous studies have presented links between allergic rhinitis (AR) and ASTH. Recently, it was suggested that , a NAD-dependent class III histone deacetylase protein, was involved in the pathogenesis of ASTH.