The impact of TeO content on radiation shielding properties for zinc-tellurite borosilicate glasses.

A novel Zinc-Tellurite borosilicate (ZTBS) glass system was successfully synthesized via the melt quench process. Its chemical composition is represented by the formula (44SiO-25BO-18NaO-6CaO-1ZrO-(6-x)ZnO-xTeO), and its weight fraction (x = 0, 2, 4, 6 wt%). The shielding properties, there is perfect agreement between the results of the theoretical calculation of the mass attenuation coefficient using the Phy-X/PSD and the compatible values derived from the WinXCom databases.

FCRL1 and BAFF mRNA Expression as Novel Diagnostic and Prognostic Biomarkers in Diffuse Large B-Cell Lymphoma: Expression Signatures Predict R-CHOP Therapy Response and Survival.

This study investigated the diagnostic, prognostic, and therapeutic significance of Fc receptor-like 1 () and B-cell activating factor () mRNA expression in Egyptian patients with diffuse large B-cell lymphoma (DLBCL) undergoing the standard R-CHOP regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) using quantitative real-time PCR (RT-qPCR). The results demonstrated that and mRNA expression were significantly elevated in DLBCL patients compared to healthy controls. A strong positive correlation existed between and expression levels.

Influence of different polymeric materials of implant and attachment on stress distribution in implant-supported overdentures: a three-dimensional finite element study.

Purpose: Investigating high performance thermoplastic polymers as substitutes to titanium alloy, in fabrication of implants and attachments to support mandibular overdenture, aiming to overcome stress shielding effect of titanium alloy implants. AIM OF STUDY: Assessment of stress distribution in polymeric prosthetic components and bone around polymeric implants, in case of implant-supported mandibular overdenture.

Materials And Methods: 3D finite element model was established for mandibular overdenture, supported bilaterally by two implants at canine region, and retained by two ball attachments.

Pyrroloquinoline quinone-loaded coaxial nanofibers prevent oxidative stress after spinal cord injury.

Oxidative stress plays a major role in the secondary injury of the spinal cord tissue due to the high lipid content of nervous tissue. In the present study, coaxial nanofibers were loaded with the natural antioxidant pyrroloquinoline quinone (PQQ) and used as an implantable drug-delivery system and a scaffold post-SCI. The obtained data show that the concentration of NO and the activity of inducible nitric oxide synthase (iNOS) were significantly ( < 0.

Trastuzumab Induces Apoptosis and Cell Cycle Arrest in Triple-Negative Breast Cancer, Suggesting Repurposing Potential.

Background: Breast cancer remains the most common invasive cancer in women worldwide. Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options. Trastuzumab (Tz) is typically used to treat HER2-positive breast cancers, but its potential in TNBC is unclear.

Electrospun zinc oxide nanoscaffolds: a targeted and selective anticancer approach.

This study aims to prepare, characterize, and evaluate zinc oxide nanoscaffolds (ZnO NSs) as a potential anticancer drug that selectively targets malignant cells while remaining non-toxic to normal cells. Electrospun NSs were fabricated and loaded with varying concentrations of ZnO nanoparticles (NPs). The uniform morphology of the fabricated samples was confirmed through Field Emission Scanning Electron Microscope (FESEM) imaging.

Advanced biomaterials for regenerative medicine and their possible therapeutic significance in treating COVID-19: a critical overview.

The potential of biomaterials in medical sciences has attracted much interest, especially in promoting tissue regeneration and controlling immune responses. As the COVID-19 pandemic broke out, there was an increased interest in understanding more about how biomaterials could be employed to fight this dreaded disease, especially in the context of regenerative medicine. Out of the numerous regenerative medicine possibilities, stem cells and scaffolding (grafting) technology are two major areas in modern medicine and surgery.

Effect of adding systematic desensitization to goal-directed paradigm on risk of falling in patients with stroke: a randomized controlled trial.

Background: Improvement in rehabilitation outcomes for patients suffering from chronic stroke can be attained through systematic desensitization of their fear of falling, which in turn reduces the risk of falling.

Purpose: This study aimed to examine the effect of adding systematic desensitization to a goal-directed paradigm on functional performance, balance, risk of falling, and fear of falling among chronic ischemic stroke patients.

Methodology: Two equally sized groups, each comprising 40 stroke patients of both sexes, were randomly divided.

Effect of Extracorporeal Shock Wave on Upper Trapezius Trigger Points in Patients With Cervicogenic Headache: A Randomized Clinical Trial.

Objective: A recent study was designed to ascertain the impact of extracorporeal shock wave therapy on upper trapezius trigger points in cervicogenic headaches patients.

Design: A double-blinded randomized controlled trial study, in which 50 participants (11 male and 39 female) aged between 20-40 with cervicogenic headache were subdivided with randomization to group (A), which received traditional physical therapy and sham shock wave therapy, and group (B), which received traditional physical therapy and actual shock wave therapy. All assessments were performed by a therapist before and after the treatment program (4 wks).

Effect of home-based pulmonary rehabilitation on exercise capacity in post COVID-19 patients: a randomized controlled trail.

Background: Coronavirus 2019 (COVID-19) is an epidemic condition that compromises various consequences. The goal of this study was to investigate the effect of home-based pulmonary rehabilitation on exercise capacity in patients with post COVID-19 syndrome.

Methods: The study was designed as a randomized control trial.

FolE gene expression for folic acid productivity from optimized and characterized probiotic Lactobacillus delbrueckii.

Background: Lactobacillus delbrueckii was one of the most common milk lactic acid bacterial strains (LAB) which characterized as probiotic with many health influencing properties.

Results: Among seven isolates, KH1 isolate was the best producer of folic acid with 100 µg/ml after 48 h of incubation; FolE gene expression after 24 h of incubation was in the highest value in case of KH1 with three folds. Lactose was the best carbon source for this KH1, besides the best next isolates KH80 and KH98.