160 results match your criteria: "Al Jouf University[Affiliation]"

Comparative Study of Serum Lipid Profiles in Nepalese Cancer Patients Attending a Tertiary Care Hospital.

Asian Pac J Cancer Prev

February 2018

Department of Clinical Laboratory Science, College of Applied Medical Sciences, Al Jouf University, Saudi Arabia. Email:

Significant efforts have been made to study cancer at the biochemical and cellular level and identify factors associated with progression. The aim of this hospital based randomized comparative study at the Nepalese Army Institute of Health science hospital was to assess factors in 52 people diagnosed with different types of cancer and 56 normal control persons. Fasting blood samples were analyzed for serum total cholesterol (TC), high density lipoprotein (HDL), triglycerides (TG) and low density lipoprotein (LDL).

View Article and Find Full Text PDF

Incidence and Pattern of Mandible Fractures in the Madinah Region: A Retrospective Study.

J Nat Sci Biol Med

January 2018

Department of Oral Medicine and Radiology, College of Dentistry, Al Jouf University, Sakakah, Kingdom of Saudi Arabia.

Objectives: The objective of the study is to study the incidence and pattern of mandible fractures in the holy city of Madinah in the Kingdom of Saudi Arabia over a retrospective period of 3 years from 2013 (1434H) to 2016 (1436H) and to compare the results with those from other regions of Saudi Arabia and elsewhere.

Materials And Methods: Relevant data of patients admitted to the King Fahad Hospital, Madinah with a fracture of the mandible during the study were collected from their medical records and radiographs. The age, gender, etiology, role of the patient, site, and number of fractures in the patients were evaluated.

View Article and Find Full Text PDF

Brucellosis is a zoonotic infectious disease that is known endemic infection in Saudi Arabia. Yet, this infection has not been reported as evident cause of prostatic abscess. we present a new case of prostatic abscess caused by brucella organism proven using pus culture and serology.

View Article and Find Full Text PDF

Traditionally, periodontics has been instrumental in treating hard- and soft-tissue defect. Surgical and regenerative periodontal procedures can reconstruct the three-dimensional architecture of the hard- and soft-tissue defect. However, at times, these invasive procedures leave the patients with an esthetic problem.

View Article and Find Full Text PDF

Objective: To evaluate the students' experience with problem-based learning.

Methods: This cross-sectional, qualitative study was conducted at the College of Medicine, Al Jouf University, Sakakah, Saudi Arabia, in October 2015, and comprised medical students of the 1st to 5th levels. Interviews were conducted using Students' Course Experience Questionnaire.

View Article and Find Full Text PDF

Background: During the recent decade, several studies about prevalence of symptom-based GERD have revealed increase of its prevalence. In addition to the highly disturbing typical symptoms, it has a series of known consequences and may affect the quality of life.

Objective: To determine the prevalence of gastroesophageal reflux disease (GERD) as well as their main characteristics and risk factors among the population of Arar City, Northern Saudi Arabia.

View Article and Find Full Text PDF

Introduction: The aim of this study was to evaluate the effect of low-level laser irradiation applied at 3-week intervals on orthodontic tooth movement and pain associated with orthodontic tooth movement using self-ligating brackets.

Methods: Twenty-two patients (11 male, 11 female; mean age, 19.8 ± 3.

View Article and Find Full Text PDF

SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress.

Antioxid Redox Signal

May 2018

1 Instituto de Investigaciones Biomédicas Alberto Sols (Centro Mixto CSIC-UAM) , Madrid, Spain .

Aims: Sirtuin 1 (SIRT1) is a key player in liver physiology and a therapeutic target against hepatic inflammation. We evaluated the role of SIRT1 in the proinflammatory context and oxidative stress during acetaminophen (APAP)-mediated hepatotoxicity.

Results: SIRT1 protein levels decreased in human and mouse livers following APAP overdose.

View Article and Find Full Text PDF

Background: Recent advancements in clinical dentistry have increased the possibilities of surgical procedures in the mental region. A detailed knowledge of mental foramen (MF) morphometry is significant to preserve integrity of the mental nerve trunk in surgical interventions such as orthognathic surgery, implant placement and anaesthetic block.

Objective: The aim of this study was to determine the most accurate position of the mental foramen by using new assessment approach in a sample of dental patients presenting to the specialist dental clinic, College of Dentistry, Al Jouf University, Saudi Arabia.

View Article and Find Full Text PDF

Objectives: Assessment of treatment outcome is the only non-invasive approach to identify the effects of cleft lip and palate repair and modify management accordingly. Here the aim is to assess the outcome of complete unilateral cleft lip and palate (CUCLP) patients using EUROCRAN index and to check whether there are any factors associated with the treatment outcome.

Materials And Methods: It is a retrospective cross sectional study.

View Article and Find Full Text PDF

In this work, the adsorption of chemical oxygen demand (COD) and biological oxygen demand (BOD) from treated sewage with low-cost activated carbon prepared from date palm shell waste by chemical activation method was studied. Different parameters affecting the adsorption process such as carbon dose, pH, contact time, agitation rate, and temperature were studied. Adsorption equilibrium was attained after 150 min at pH 6.

View Article and Find Full Text PDF

Formulation and optimization of lacidipine loaded niosomal gel for transdermal delivery: In-vitro characterization and in-vivo activity.

Biomed Pharmacother

September 2017

Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India. Electronic address:

The aim of the present research work is to formulate lacidipine (LAC) loaded niosomes formulation for the management of hypertension by thin film hydration technique. The developed formulations were statistically optimized by four factors, three levels Box-Behnken design and were evaluated for vesicle size, entrapment efficiency, and flux. The optimized LAC niosomes was further evaluated for permeation depth by confocal laser scanning microscopy (CLSM) and converted to gel formulation.

View Article and Find Full Text PDF

The wax sculpting of a maxillofacial prosthesis is challenging, time-consuming, and requires great skill. Rapid prototyping (RP) systems allow these hurdles to be overcome by enabling the creation of a customized 3D model of the desired prosthesis. Geomagic and Mimics are the most suitable software programs with which to design such prostheses.

View Article and Find Full Text PDF

Introduction: Primary osteosarcoma of the breast is extremely rare, and an osteosarcoma arising from an intraductal papilloma is exceptional.

Case Presentation: A 72-year-old Saudi Arabian woman presented with a solid, bone-containing breast mass that was diagnosed as primary osteosarcoma of the breast on biopsy. She had a history of untreated intraductal papilloma.

View Article and Find Full Text PDF

Introduction: Xerostomia is a subjective feeling of dryness commonly seen in elderly populations which impairs the quality of life. Due to loss of lubricating property of saliva the buccal mucosa, tongue and lips tend to stick leading to dry, freckled, ulcerated and sore mucosa which is of major concern to the patient to use complete denture.

Aim: The aim of the study was to assess the relation between oral dryness score and denture satisfaction among elderly patients.

View Article and Find Full Text PDF

Molecular interactions of dioxins and DLCs with the xenosensors (PXR and CAR): An in silico risk assessment approach.

J Mol Recognit

December 2017

Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.

Dioxins and dioxin-like compounds (DLCs) are known to cause endocrine disruption in humans and animals. Being lipophilic xenobiotic chemicals, they can be easily absorbed into the biological system from the surrounding environments, thereby causing various health dysfunctions. In the present study, a total of 100 dioxins and DLCs were taken, and their binding pattern was assessed with the xenosensors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) in comparison with the corresponding known inhibitors and a well-studied endocrine disrupting xenobiotic, bisphenol A (BPA).

View Article and Find Full Text PDF

Tinospora species: An overview of their modulating effects on the immune system.

J Ethnopharmacol

July 2017

Pharmaceutical Chemistry Department, College of Pharmacy, Al Jouf University, Sakaka Al Jouf 2014, Saudi Arabia.

Ethnopharmacological Relevance: Studies on the effects of natural immunomodulators to heal various diseases related to the immune system have been a growing interest in recent years. Amongst the medicinal plants, Tinospora species (family; Menispermaceae) have been one of the widely investigated plants for their modulating effects on the immune system due to their wide use in ethnomedicine to treat various ailments related to immune-related diseases. However, their ethnopharmacological uses are mainly with limited or without scientific basis.

View Article and Find Full Text PDF

Nano-carriers for the Treatment of Tuberculosis.

Recent Pat Antiinfect Drug Discov

July 2018

Glocal School of Pharmacy, Glocal University, Saharanpur-247121, Uttar Pradesh, India.

Background: Nano size based drug delivery systems are an emerging technique with the potential to develop new strategies involving handling of drugs at the nanometer scale. There are many nano-based drug delivery systems that have been extensively reported as drug carriers for the treatment of tuberculosis.

Methods: There are numerous nano sized drug delivery systems like lipid nanoparticles, polymeric micelle, carbon nanotubes and polymeric nanoparticles that have been reported for a long time to treat diseases.

View Article and Find Full Text PDF

Background: The manifestations of oral changes and disorders affecting the geriatric population are different from the rest of the population. Inaccessibility to dental care is a compelling impediment to avail oral health services.

Objective: The aims were to assess the dental and oral problems and to find out the determinants of oral health seeking behaviour among elderly population of Al-Jouf province, Saudi Arabia.

View Article and Find Full Text PDF

Statement Of Problem: The detrimental effect of extruded excess cement on peri-implant tissue has been well documented. Although several techniques have been proposed to reduce this effect by decreasing the amount of extruded cement, how the space size of the abutment screw access channel (SAC) affects the amount of extruded cement and marginal accuracy is unclear.

Purpose: The purpose of this in vitro study was to evaluate the effect of the size of the unfilled space of the abutment SAC on the amount of extruded excess cement and the marginal accuracy of zirconia copings.

View Article and Find Full Text PDF

Present study, was an effort to scrutinize the molecular and biochemical role of ibuprofen and thiamine combination in diethylnitrosamine (DEN)-induced HCC in Wistar rats. Single intraperitoneal injection of DEN (200 mg/kg) was used for induction of HCC in rats. The rats were divided into eight various groups.

View Article and Find Full Text PDF

Background: Leathery Murdah, Terminalia coriacea (Roxb.) Wight & Arn. from family Combretaceae is used in Ayurveda and Siddha traditional systems of medicine to heal ulcers.

View Article and Find Full Text PDF

Purpose: At present, commercially available antiurolithic drugs have more adverse effects than potential therapeutic or preventive effects with chronic use. With this in mind, the present study was designed to assess the antiurolithic effect of olive oil in a mouse model of ethylene glycol (EG)-induced urolithiasis.

Materials And Methods: Adult albino mice were divided into 6 groups.

View Article and Find Full Text PDF

Background: Cleft lip and palate (CLP) is one of the most common birth defects. Multiple factors are believed to be responsible for an unfavorable dental arch relationship in CLP. Facial growth (maxillary) retardation, which results in class III malocclusion, is the primary challenge that CLP patients face.

View Article and Find Full Text PDF