CO₂ Supercritical Extraction of Essential Oil of Jordanian Rosemary.

Experimental investigation of supercritical fluid extraction (SFE) of active ingredients from rosemary herb has been performed. Carbon dioxide (CO₂) was used as a solvent with ethanol as a trapping agent. This work showed that the SFE can be an exceptional alternative to the use of chemical solvents.

A Descriptive Review of the Prevalence and Usage of Traditional and Complementary Medicine among Saudi Diabetic Patients.

Diabetes mellitus represents a major burden in Saudi Arabia where seven million (20% of population) are living with diabetes. This article reviews the literature on usage of traditional and complementary medicine (T&CM) therapies among Saudi diabetic patients, focusing in particular on identifying the prevalence as well as discussing their safety and efficacy. Three databases (PubMed, Cochrane, and ScienceDirect) were searched prior to December 10, 2017, for articles published in peer-reviewed journals that reported primary data on the use of traditional and complementary medicine therapies among diabetic patients in Saudi Arabia.

RADIATION DOSE DETERMINATION IN ABDOMINAL CT EXAMINATIONS OF CHILDREN AT SUDANESE HOSPITALS USING SIZE-SPECIFIC DOSE ESTIMATES.

In this study, we thought to estimate the radiation exposure of children undergoing multi-detector CT examinations using size-specific dose estimates (SSDE). Console-displayed volume computed tomography dose index (CTDIvol) were recorded for a total of 78 paediatric abdominal CT examinations performed in six hospitals. Measurements of the patient diameters were taken from the mid-slice location on the transverse and scout CT images.

HLA-DQB1*06:02 allele frequency and clinic-polysomnographic features in Saudi Arabian patients with narcolepsy.

Background: Narcolepsy is an uncommon neurological disorder characterised by irresistible spells of sleep associated with abnormal rapid eye movement (REM) sleep. The association between narcolepsy and human leukocyte antigen HLA- DQB1*06:02 has been established elsewhere but remains to be investigated among Saudi Arabian patients with narcolepsy.

Methods: A total of 29 Saudi patients with type I or type 2 narcolepsy comprising of 23 (79%) males and 6 (21%) females with a mean age of 17.

The health of Saudi older adults; results from the Saudi National Survey for Elderly Health (SNSEH) 2006-2015.

Objectives: To Describe the Saudi older adult (SOA) characteristics and Introduce the Saudi National Survey for Elderly Health (SNSEH).

Methods: The SNSEH, a population-based nationally-representative survey, was used. Subjects were included in 2006-2007, using random-cluster sampling utilizing probability proportional to size approach, and followed-up to determine their vital status until June 2015.

Top 10 most used drugs in the Kingdom of Saudi Arabia 2010-2015.

Medications usage has become a significant part of contemporary life. Many studies indicate that there is an excessive use and a considerable waste of medicines. This descriptive study aims at identifying the most used medicines in Saudi Arabia from 2010 to 2015 according to the statistics of specialized companies in the field.

Fabrication of hybrid nanocomposite derived from chitosan as efficient electrode materials for supercapacitor.

A novel high-performance supercapacitor was fabricated using spinal (nickel ferrite) nanoparticles uniformly implanted into nitrogen-doped carbon matrix. The nanocomposite was fabricated with bimetallic polymer complexes for the first time. The fabricated nanocomposite was characterized using FTIR, TGA, Raman, XRD, BET, XPS, SEM and TEM technique.

Quantum Quantifiers for an Atom System Interacting with a Quantum Field Based on Pseudoharmonic Oscillator States.

We develop a useful model considering an atom-field system interaction in the framework of pseudoharmonic oscillators. We examine qualitatively the different physical quantities for a two-level atom (TLA) system interacting with a quantized coherent field in the context of photon-added coherent states of pseudoharmonic oscillators. Using these coherent states, we solve the model that exhibits the interaction between the TLA and field associated with these kinds of potentials.

Effect of the LEGe detector collimators on K-series peaks and Compton scattering in XRF analysis using gamma rays.

The effect of a low-energy germanium detector collimator with different diameters on the measurement of the X-ray fluorescence of palladium (Pd) was studied experimentally. Changes in the Pd K-series and Compton scattering peaks were measured and analysed with and without a detector collimator, where for the former, collimators with different diameters were used. The signal-to-noise ratio increased when a shielding collimator was used with a narrow detector collimator.

A brief illustration of the official national standards for the safe use of cupping therapy (Hijama) in Saudi Arabia.

Cupping therapy (Hijama in Arabic) is a popular traditional treatment especially in Asia, the Middle East and Central Europe. Traditionally, cupping therapy has been one of the most used practices in Saudi Arabia. Standardization of the practice of cupping therapy is a very important step to eliminate or reduce any adverse events related to cupping.

Impact of p53 arg72pro SNP on Breast Cancer Risk in North Indian Population.

Background: Genetic changes in p53 gene contribute to breast cancer susceptibility.

Objective And Methods: A case-control study and a meta-analysis were performed to investigate the role of p53 codon72 SNP with breast cancer susceptibility in Indian women.

Results: p53 heterozygous arginine variant was associated with decreased risk of breast cancer in total cohort.

The efficacy and safety of anticoagulation in cerebral vein thrombosis: A systematic review and meta-analysis.

Background: Anticoagulation with unfractionated heparin (UFH) or low molecular weight heparin (LMWH) is the mainstay for the treatment of patients with acute cerebral vein thrombosis (CVT) with or without intracranial hemorrhage (ICH).

Aim: We conducted a systematic review and meta-analysis to determine the efficacy and safety of LMWH compared to UFH for the treatment of acute CVT.

Methods: An electronic search of MEDLINE, Pubmed, CENTRAL and Google Scholar was performed.

Study on the interaction of antidiabetic drug Pioglitazone with calf thymus DNA using spectroscopic techniques.

Pioglitazone is an antidiabetic drug used to treat type 2 diabetes mellitus. Interaction of Pioglitazone with calf thymus DNA was investigated using multispectroscopic techniques and molecular docking study. Quenching and binding constant was calculated at 3 different temperatures.

Knowledge and practice regarding contact lens among Saudi urban contact lens users.

Purpose: To assess the level and determinants of knowledge and practice regarding contact lens (CL) and its accessories among adult Saudi CL users.

Methods: This survey was conducted in 2015 for Saudi contact lens users visiting a Mall in Riyadh, Saudi Arabia. The questions were related to knowledge about contact lenses, correct CL and accessories usage.

Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients.

Background: Nevus lipomatosis cutaneous superficialis (NLCS) is a rare hamartoma of mature adipose tissue characterized by solitary or multiple, soft, skin-colored or yellowish lobules that may coalesce to give rise to plaques with a cerebriform surface. There are two clinical types: (1) multiple lesions that are usually presented in a segmental distribution and (2) a solitary papule or nodule.

Aim And Objective: To study the clinical and histopathological features of 5 Saudi patients with NLCS.

Kleine-Levin syndrome is associated with LMOD3 variants.

Kleine-Levin syndrome (KLS) is a rare periodic hypersomnia with associated behavioural abnormalities but with often favourable prognosis. There is excess risk of KLS in first-degree relatives, suggesting a strong genetic contribution. So far, no mutation is identified in KLS and comprehensive genetic analysis of affected individuals is lacking.

How does the utilization of diabetes dietitian and educator service in Saudi Arabia affect glycemic outcomes?

Background: Despite the acknowledgment that the services of diabetes educator and dietician affect outcome, the level of utilization of these services in the Saudi Arabian public health-care system is not known. The aims of the study were to establish the percentage of patients with diabetes mellitus (DM) followed up by a diabetic educator and a dietician in a tertiary center in Saudi Arabia and associations between follow-up by a diabetic educator and a dietician and glycemic control.

Materials And Methods: This was a cross-sectional study of 490 diabetic patients who attended the diabetic outpatient clinic consecutively at a public health-care institution in Riyadh.

A Quality Model to Select Patients in Cupping Therapy Clinics: A New Tool for Ensuring Safety in Clinical Practice.

Cupping therapy is a popular treatment in various countries and regions, including Saudi Arabia. Cupping therapy is regulated in Saudi Arabia by the National Center for Complementary and Alternative Medicine, Ministry of Health. The authors recommend that this quality model to select patients in cupping clinics - version 1 (QMSPCC-1)-be used routinely as part of clinical practice and quality management in cupping clinics.

Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review.

Background: Malaria, Dengue and Chikungunya are vector borne diseases with shared endemic profiles and symptoms. Coinfections with any of these diseases could have fatal outcomes if left undiagnosed. Understanding the prevalence and distribution of coinfections is necessary to improve diagnosis and designing therapeutic interventions.

Evidence supporting a mechanistic role of sirtuins in mood and metabolic disorders.

Sirtuins are NAD-dependent histone deacetylases that play essential roles in cell survival, energy metabolism, inflammation, and aging; therefore, sirtuins are potential therapeutic targets in the treatment of type 2 diabetes, cancer, inflammatory and metabolic disorders, and neurodegenerative diseases. Available evidence provides the basis for hypothesizing that sirtuins 1, 2, and 3 (SIRT1, SIRT2, and SIRT3) may have a mechanistic role subserving mood disorders (i.e.

Application of phenolic compounds as natural dye extracted from date-pits: dyeing studies of modified acrylic fibres.

This research work involves the dyeing of acrylic fabric with natural dye extracted from date pits powders using Soxhlet extraction process. The effect of dye bath pH, salt concentration, dyeing time and temperature were studied. The optimal dyeing conditions where pH 4, 0 g/L salt, 60 min, and 80 °C.

The protective role of quercetin and arginine on gold nanoparticles induced hepatotoxicity in rats.

Background: The aim of the study was to confirm the hepatotoxicity induced by small-sized gold nanoparticles (GNPs) and evaluate the role of quercetin (Qur) and arginine (Arg) against hepatotoxicity caused by GNPs.

Methods: Twenty-five healthy male Wistar-Kyoto rats were used. GNPs were administered intraperitoneally to these rats at the dose of 50 μL for seven consecutive days.

MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells.

The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of angiogenesis-related genes, which can also play a major role in tumor propagation and increase its metastatic potential. In the present study, we have used the human angiogenesis RT² profiler PCR array to compare the gene expression profile between LNCaP and LNCaP-MST (MDM2 transfected) prostate cancer cells, along with LNCaP-MST cells treated with Nutlin-3, an MDM2 specific inhibitor.

To Decipher the Proteins Targeting into the Endoplasmic Reticulum and Their Implications in Prostate Cancer Etiology Using Next-Generation Sequencing Data.

Cancer was initially considered a genetic disease. However, recent studies have revealed the connection between bacterial infections and growth of different types of cancer. The enteroinvasive strain of alters the normal behavior of host cells that may result in the growth of prostate cancer.